메뉴 건너뛰기




Volumn 12, Issue 43, 2006, Pages 6926-6932

Role of ethanol in the regulation of hepatic stellate cell function

Author keywords

Acetaldehyde; Ethanol; Hepatic stellate cells; Liver fibrosis; Transciption factors; Transforming growth factor 1; Type I collagen gene

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALPHA SMOOTH MUSCLE ACTIN; BASIC TRANSCRIPTION ELEMENT BINDING PROTEIN; CCAAT ENHANCER BINDING PROTEIN; COLLAGEN TYPE 1; GELATINASE A; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NUCLEAR FACTOR I; RETINOID; STRESS ACTIVATED PROTEIN KINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA1;

EID: 33751536833     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v12.i43.6926     Document Type: Review
Times cited : (47)

References (71)
  • 1
    • 14844304367 scopus 로고    scopus 로고
    • Metabolism of alcohol
    • Lieber CS. Metabolism of alcohol. Clin Liver Dis 2005; 9: 1-35
    • (2005) Clin Liver Dis , vol.9 , pp. 1-35
    • Lieber, C.S.1
  • 2
    • 12844288099 scopus 로고    scopus 로고
    • Alcoholic fatty liver: Its pathogenesis and mechanism of progression to inflammation and fibrosis
    • Lieber CS. Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis. Alcohol 2004; 34: 9-19
    • (2004) Alcohol , vol.34 , pp. 9-19
    • Lieber, C.S.1
  • 3
  • 4
    • 0035178103 scopus 로고    scopus 로고
    • Alcoholic liver injury: Pathogenesis and therapy in 2001
    • Lieber CS. Alcoholic liver injury: pathogenesis and therapy in 2001. Pathol Biol (Paris) 2001; 49: 738-752
    • (2001) Pathol Biol (Paris) , vol.49 , pp. 738-752
    • Lieber, C.S.1
  • 5
    • 0031035695 scopus 로고    scopus 로고
    • Ethanol metabolism, cirrhosis and alcoholism
    • Lieber CS. Ethanol metabolism, cirrhosis and alcoholism. Clin Chim Acta 1997; 257: 59-84
    • (1997) Clin Chim Acta , vol.257 , pp. 59-84
    • Lieber, C.S.1
  • 6
    • 0034975104 scopus 로고    scopus 로고
    • The role of acetaldehyde in the actions of alcohol (update 2000)
    • Eriksson CJ. The role of acetaldehyde in the actions of alcohol (update 2000). Alcohol Clin Exp Res 2001; 25: 15S-32S
    • (2001) Alcohol Clin Exp Res , vol.25
    • Eriksson, C.J.1
  • 7
    • 0037371816 scopus 로고    scopus 로고
    • Oxidants and antioxidants in alcohol-induced liver disease
    • Arteel GE. Oxidants and antioxidants in alcohol-induced liver disease. Gastroenterology 2003; 124: 778-790
    • (2003) Gastroenterology , vol.124 , pp. 778-790
    • Arteel, G.E.1
  • 8
    • 0033057124 scopus 로고    scopus 로고
    • Acetaldehyde-mediated collagen regulation in hepatic stellate cells
    • Greenwel P. Acetaldehyde-mediated collagen regulation in hepatic stellate cells. Alcohol Clin Exp Res 1999; 23: 930-933
    • (1999) Alcohol Clin Exp Res , vol.23 , pp. 930-933
    • Greenwel, P.1
  • 9
    • 0032989347 scopus 로고    scopus 로고
    • Stellate cell activation in alcoholic fibrosis - An overview
    • Friedman SL. Stellate cell activation in alcoholic fibrosis - an overview. Alcohol Clin Exp Res 1999; 23: 904-910
    • (1999) Alcohol Clin Exp Res , vol.23 , pp. 904-910
    • Friedman, S.L.1
  • 10
    • 0036139102 scopus 로고    scopus 로고
    • Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species
    • Nieto N, Friedman SL, Cederbaum AI. Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species. Hepatology 2002; 35: 62-73
    • (2002) Hepatology , vol.35 , pp. 62-73
    • Nieto, N.1    Friedman, S.L.2    Cederbaum, A.I.3
  • 12
    • 0025272680 scopus 로고
    • Sensitization of hepatic lipocytes by high-fat diet to stimulatory effects of Kupffer cell-derived factors: Implication in alcoholic liver fibrogenesis
    • Matsuoka M, Zhang MY, Tsukamoto H. Sensitization of hepatic lipocytes by high-fat diet to stimulatory effects of Kupffer cell-derived factors: implication in alcoholic liver fibrogenesis. Hepatology 1990; 11: 173-182
    • (1990) Hepatology , vol.11 , pp. 173-182
    • Matsuoka, M.1    Zhang, M.Y.2    Tsukamoto, H.3
  • 13
    • 0029938025 scopus 로고    scopus 로고
    • Effects of dietary polyunsaturated fat on ethanol-induced Ito cell activation
    • Tsukamoto H, Cheng S, Blaner WS. Effects of dietary polyunsaturated fat on ethanol-induced Ito cell activation. Am J Physiol 1996; 270: G581-G586
    • (1996) Am J Physiol , vol.270
    • Tsukamoto, H.1    Cheng, S.2    Blaner, W.S.3
  • 15
    • 0029794132 scopus 로고    scopus 로고
    • A decade of molecular biology of retinoic acid receptors
    • Chambon P. A decade of molecular biology of retinoic acid receptors. FASEB J 1996; 10: 940-954
    • (1996) FASEB J , vol.10 , pp. 940-954
    • Chambon, P.1
  • 17
    • 0032973664 scopus 로고    scopus 로고
    • Alcohol, vitamin A, and beta-carotene: Adverse interactions, including hepatotoxicity and carcinogenicity
    • Leo MA, Lieber CS. Alcohol, vitamin A, and beta-carotene: adverse interactions, including hepatotoxicity and carcinogenicity. Am J Clin Nutr 1999; 69: 1071-1085
    • (1999) Am J Clin Nutr , vol.69 , pp. 1071-1085
    • Leo, M.A.1    Lieber, C.S.2
  • 18
    • 0032973636 scopus 로고    scopus 로고
    • Chronic alcohol intake interferes with retinoid metabolism and signaling
    • Wang XD. Chronic alcohol intake interferes with retinoid metabolism and signaling. Nutr Rev 1999; 57: 51-59
    • (1999) Nutr Rev , vol.57 , pp. 51-59
    • Wang, X.D.1
  • 21
    • 0034177719 scopus 로고    scopus 로고
    • Effect of retinoic acid on the enhancing effect of acetaldehyde on mouse type I collagen expression
    • Wang L, Attard FA, Tankersley LR, Potter JJ, Mezey E. Effect of retinoic acid on the enhancing effect of acetaldehyde on mouse type I collagen expression. Arch Biochem Biophys 2000; 376: 191-198
    • (2000) Arch Biochem Biophys , vol.376 , pp. 191-198
    • Wang, L.1    Attard, F.A.2    Tankersley, L.R.3    Potter, J.J.4    Mezey, E.5
  • 22
    • 0037666327 scopus 로고    scopus 로고
    • The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells
    • Li J, Hu W, Baldassare JJ, Bora PS, Chen S, Poulos JE, O'Neill R, Britton RS, Bacon BR. The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life Sci 2003; 73: 1083-1096
    • (2003) Life Sci , vol.73 , pp. 1083-1096
    • Li, J.1    Hu, W.2    Baldassare, J.J.3    Bora, P.S.4    Chen, S.5    Poulos, J.E.6    O'Neill, R.7    Britton, R.S.8    Bacon, B.R.9
  • 23
    • 0023847633 scopus 로고
    • Effects of ethanol, acetaldehyde, and lactate on proteoglycan synthesis and proliferation of cultured rat liver fat-storing cells
    • Gressner AM, Althaus M. Effects of ethanol, acetaldehyde, and lactate on proteoglycan synthesis and proliferation of cultured rat liver fat-storing cells. Gastroenterology 1988; 94: 797-807
    • (1988) Gastroenterology , vol.94 , pp. 797-807
    • Gressner, A.M.1    Althaus, M.2
  • 24
    • 0033117629 scopus 로고    scopus 로고
    • Dilinoleoylphospha tidylcholine decreases hepatic stellate cell activation
    • Poniachik J, Baraona E, Zhao J, Lieber CS. Dilinoleoylphospha tidylcholine decreases hepatic stellate cell activation. J Lab Clin Med 1999; 133: 342-348
    • (1999) J Lab Clin Med , vol.133 , pp. 342-348
    • Poniachik, J.1    Baraona, E.2    Zhao, J.3    Lieber, C.S.4
  • 26
    • 0032552869 scopus 로고    scopus 로고
    • Alcohol stimulates the expression of L-type voltage-operated Ca2+ channels in hepatic stellate cells
    • Itatsu T, Oide H, Watanabe S, Tateyama M, Ochi R, Sato N. Alcohol stimulates the expression of L-type voltage-operated Ca2+ channels in hepatic stellate cells. Biochem Biophys Res Commun 1998; 251: 533-537
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 533-537
    • Itatsu, T.1    Oide, H.2    Watanabe, S.3    Tateyama, M.4    Ochi, R.5    Sato, N.6
  • 27
    • 0347297564 scopus 로고    scopus 로고
    • The antioxidant (-) -epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression
    • Chen A, Zhang L, Xu J, Tang J. The antioxidant (-) -epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression. Biochem J 2002; 368: 695-704
    • (2002) Biochem J , vol.368 , pp. 695-704
    • Chen, A.1    Zhang, L.2    Xu, J.3    Tang, J.4
  • 28
    • 0034814405 scopus 로고    scopus 로고
    • Extracellular matrix degradation and the role of hepatic stellate cells
    • Benyon RC, Arthur MJ. Extracellular matrix degradation and the role of hepatic stellate cells. Semin Liver Dis 2001; 21: 373-384
    • (2001) Semin Liver Dis , vol.21 , pp. 373-384
    • Benyon, R.C.1    Arthur, M.J.2
  • 29
    • 0031593180 scopus 로고    scopus 로고
    • Ethanol induces the expression of alpha 1(I) procollagen mRNA in a co-culture system containing a liver stellate cell-line and freshly isolated hepatocytes
    • Fontana L, Jerez D, Rojas-Valencia L, Solis-Herruzo JA, Greenwel P, Rojkind M. Ethanol induces the expression of alpha 1(I) procollagen mRNA in a co-culture system containing a liver stellate cell-line and freshly isolated hepatocytes. Biochim Biophys Acta 1997; 1362: 135-144
    • (1997) Biochim Biophys Acta , vol.1362 , pp. 135-144
    • Fontana, L.1    Jerez, D.2    Rojas-Valencia, L.3    Solis-Herruzo, J.A.4    Greenwel, P.5    Rojkind, M.6
  • 30
    • 0025485813 scopus 로고
    • Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes
    • Moshage H, Casini A, Lieber CS. Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes. Hepatology 1990; 12: 511-518
    • (1990) Hepatology , vol.12 , pp. 511-518
    • Moshage, H.1    Casini, A.2    Lieber, C.S.3
  • 31
    • 0026544698 scopus 로고
    • Polyunsaturated lecithin prevents acetaldehyde-mediated hepatic collagen accumulation by stimulating collagenase activity in cultured lipocytes
    • Li J, Kim CI, Leo MA, Mak KM, Rojkind M, Lieber CS. Polyunsaturated lecithin prevents acetaldehyde-mediated hepatic collagen accumulation by stimulating collagenase activity in cultured lipocytes. Hepatology 1992; 15: 373-381
    • (1992) Hepatology , vol.15 , pp. 373-381
    • Li, J.1    Kim, C.I.2    Leo, M.A.3    Mak, K.M.4    Rojkind, M.5    Lieber, C.S.6
  • 32
    • 0025752432 scopus 로고
    • Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism
    • Casini A, Cunningham M, Rojkind M, Lieber CS. Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism. Hepatology 1991; 13: 758-765
    • (1991) Hepatology , vol.13 , pp. 758-765
    • Casini, A.1    Cunningham, M.2    Rojkind, M.3    Lieber, C.S.4
  • 33
    • 0033965330 scopus 로고    scopus 로고
    • Hydrogen peroxide: A link between acetaldehyde-elicited alpha1(I) collagen gene up-regulation and oxidative stress in mouse hepatic stellate cells
    • Greenwel P, Dominguez-Rosales JA, Mavi G, Rivas-Estilla AM, Rojkind M. Hydrogen peroxide: a link between acetaldehyde-elicited alpha1(I) collagen gene up-regulation and oxidative stress in mouse hepatic stellate cells. Hepatology 2000; 31: 109-116
    • (2000) Hepatology , vol.31 , pp. 109-116
    • Greenwel, P.1    Dominguez-Rosales, J.A.2    Mavi, G.3    Rivas-Estilla, A.M.4    Rojkind, M.5
  • 34
    • 0030586328 scopus 로고    scopus 로고
    • Activation by acetaldehyde of the promoter of the mouse alpha2(I) collagen gene when transfected into rat activated stellate cells
    • Anania FA, Potter JJ, Rennie-Tankersley L, Mezey E. Activation by acetaldehyde of the promoter of the mouse alpha2(I) collagen gene when transfected into rat activated stellate cells. Arch Biochem Biophys 1996; 331: 187-193
    • (1996) Arch Biochem Biophys , vol.331 , pp. 187-193
    • Anania, F.A.1    Potter, J.J.2    Rennie-Tankersley, L.3    Mezey, E.4
  • 35
    • 0035029397 scopus 로고    scopus 로고
    • Intracellular signaling pathways involved in acetaldehyde-induced collagen and fibronectin gene expression in human hepatic stellate cells
    • Svegliati-Baroni G, Ridolfi F, Di Sario A, Saccomanno S, Bendia E, Benedetti A, Greenwel P. Intracellular signaling pathways involved in acetaldehyde-induced collagen and fibronectin gene expression in human hepatic stellate cells. Hepatology 2001; 33: 1130-1140
    • (2001) Hepatology , vol.33 , pp. 1130-1140
    • Svegliati-Baroni, G.1    Ridolfi, F.2    Di Sario, A.3    Saccomanno, S.4    Bendia, E.5    Benedetti, A.6    Greenwel, P.7
  • 36
    • 0027965344 scopus 로고
    • Acetaldehyde regulates the gene expression of matrix-metalloproteinase-1 and -2 in human fat-storing cells
    • Casini A, Ceni E, Salzano R, Milani S, Schuppan D, Surrenti C. Acetaldehyde regulates the gene expression of matrix-metalloproteinase-1 and -2 in human fat-storing cells. Life Sci 1994; 55: 1311-1316
    • (1994) Life Sci , vol.55 , pp. 1311-1316
    • Casini, A.1    Ceni, E.2    Salzano, R.3    Milani, S.4    Schuppan, D.5    Surrenti, C.6
  • 37
    • 0035871817 scopus 로고    scopus 로고
    • Aldehydes potentiate alpha(2)(I) collagen gene activity by JNK in hepatic stellate cells
    • Anania FA, Womack L, Jiang M, Saxena NK. Aldehydes potentiate alpha(2)(I) collagen gene activity by JNK in hepatic stellate cells. Free Radic Biol Med 2001; 30: 846-857
    • (2001) Free Radic Biol Med , vol.30 , pp. 846-857
    • Anania, F.A.1    Womack, L.2    Jiang, M.3    Saxena, N.K.4
  • 38
    • 0037115736 scopus 로고    scopus 로고
    • Acetaldehyde stimulates the activation of latent transforming growth factor-beta1 and induces expression of the type II receptor of the cytokine in rat cultured hepatic stellate cells
    • Chen A. Acetaldehyde stimulates the activation of latent transforming growth factor-beta1 and induces expression of the type II receptor of the cytokine in rat cultured hepatic stellate cells. Biochem J 2002; 368: 683-693
    • (2002) Biochem J , vol.368 , pp. 683-693
    • Chen, A.1
  • 39
    • 0032986374 scopus 로고    scopus 로고
    • Acetaldehyde enhances murine alpha2(I) collagen promoter activity by Ca2+-independent protein kinase C activation in cultured rat hepatic stellate cells
    • Anania FA, Womack L, Potter JJ, Mezey E. Acetaldehyde enhances murine alpha2(I) collagen promoter activity by Ca2+-independent protein kinase C activation in cultured rat hepatic stellate cells. Alcohol Clin Exp Res 1999; 23: 279-284
    • (1999) Alcohol Clin Exp Res , vol.23 , pp. 279-284
    • Anania, F.A.1    Womack, L.2    Potter, J.J.3    Mezey, E.4
  • 40
    • 0028360492 scopus 로고
    • Acetaldehyde induces c-fos and c-jun proto-oncogenes in fat-storing cell cultures through protein kinase C activation
    • Casini A, Galli G, Salzano R, Ceni E, Franceschelli F, Rotella CM, Surrenti C. Acetaldehyde induces c-fos and c-jun proto-oncogenes in fat-storing cell cultures through protein kinase C activation. Alcohol Alcohol 1994; 29: 303-314
    • (1994) Alcohol Alcohol , vol.29 , pp. 303-314
    • Casini, A.1    Galli, G.2    Salzano, R.3    Ceni, E.4    Franceschelli, F.5    Rotella, C.M.6    Surrenti, C.7
  • 41
    • 0036107548 scopus 로고    scopus 로고
    • Transcriptional regulation of hepatic stellate cell activation
    • Mann DA, Smart DE. Transcriptional regulation of hepatic stellate cell activation. Gut 2002; 50: 891-896
    • (2002) Gut , vol.50 , pp. 891-896
    • Mann, D.A.1    Smart, D.E.2
  • 42
    • 0034813009 scopus 로고    scopus 로고
    • Transcriptional regulation in hepatic stellate cells
    • Eng FJ, Friedman SL. Transcriptional regulation in hepatic stellate cells. Semin Liver Dis 2001; 21: 385-395
    • (2001) Semin Liver Dis , vol.21 , pp. 385-395
    • Eng, F.J.1    Friedman, S.L.2
  • 43
    • 0034033855 scopus 로고    scopus 로고
    • The DNA binding protein BTEB mediates acetaldehyde-induced, jun N-terminal kinase-dependent alphaI(I) collagen gene expression in rat hepatic stellate cells
    • Chen A, Davis BH. The DNA binding protein BTEB mediates acetaldehyde-induced, jun N-terminal kinase-dependent alphaI(I) collagen gene expression in rat hepatic stellate cells. Mol Cell Biol 2000; 20: 2818-2826
    • (2000) Mol Cell Biol , vol.20 , pp. 2818-2826
    • Chen, A.1    Davis, B.H.2
  • 44
    • 0034213670 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein beta mediates the activation of the murine alpha1(I) collagen promoter by acetaldehyde
    • Attard FA, Wang L, Potter JJ, Rennie-Tankersley L, Mezey E. CCAAT/ enhancer binding protein beta mediates the activation of the murine alpha1(I) collagen promoter by acetaldehyde. Arch Biochem Biophys 2000; 378: 57-64
    • (2000) Arch Biochem Biophys , vol.378 , pp. 57-64
    • Attard, F.A.1    Wang, L.2    Potter, J.J.3    Rennie-Tankersley, L.4    Mezey, E.5
  • 45
    • 0034809307 scopus 로고    scopus 로고
    • Identification of new sites of binding and activation of the murine alpha1(I) collagen promoter by CCAAT/enhancer binding protein beta
    • Attard FA, Wang L, Potter JJ, Rennie-Tankersley L, Mezey E. Identification of new sites of binding and activation of the murine alpha1(I) collagen promoter by CCAAT/enhancer binding protein beta. DNA Cell Biol 2001; 20: 455-463
    • (2001) DNA Cell Biol , vol.20 , pp. 455-463
    • Attard, F.A.1    Wang, L.2    Potter, J.J.3    Rennie-Tankersley, L.4    Mezey, E.5
  • 46
    • 0029032389 scopus 로고
    • Effects of acetaldehyde on nuclear protein binding to the nuclear factor I consensus sequence in the alpha 2(I) collagen promoter
    • Anania FA, Potter JJ, Rennie-Tankersley L, Mezey E. Effects of acetaldehyde on nuclear protein binding to the nuclear factor I consensus sequence in the alpha 2(I) collagen promoter. Hepatology 1995; 21: 1640-1648
    • (1995) Hepatology , vol.21 , pp. 1640-1648
    • Anania, F.A.1    Potter, J.J.2    Rennie-Tankersley, L.3    Mezey, E.4
  • 47
    • 0031149330 scopus 로고    scopus 로고
    • Effect of acetaldehyde on Sp1 binding and activation of the mouse alpha 2(I) collagen promoter
    • Miao K, Potter JJ, Anania FA, Rennie-Tankersley L, Mezey E. Effect of acetaldehyde on Sp1 binding and activation of the mouse alpha 2(I) collagen promoter. Arch Biochem Biophys 1997; 341: 140-152
    • (1997) Arch Biochem Biophys , vol.341 , pp. 140-152
    • Miao, K.1    Potter, J.J.2    Anania, F.A.3    Rennie-Tankersley, L.4    Mezey, E.5
  • 49
    • 1442299357 scopus 로고    scopus 로고
    • MAP kinase signaling in diverse effects of ethanol
    • Aroor AR, Shukla SD. MAP kinase signaling in diverse effects of ethanol. Life Sci 2004; 74: 2339-2364
    • (2004) Life Sci , vol.74 , pp. 2339-2364
    • Aroor, A.R.1    Shukla, S.D.2
  • 51
    • 0034733746 scopus 로고    scopus 로고
    • Ethanol and arachidonic acid increase alpha 2(I) collagen expression in rat hepatic stellate cells overexpressing cytochrome P450 2E1. Role of H2O2 and cyclooxygenase-2
    • Nieto N, Greenwel P, Friedman SL, Zhang F, Dannenberg AJ, Cederbaum AI. Ethanol and arachidonic acid increase alpha 2(I) collagen expression in rat hepatic stellate cells overexpressing cytochrome P450 2E1. Role of H2O2 and cyclooxygenase-2. J Biol Chem 2000; 275: 20136-20145
    • (2000) J Biol Chem , vol.275 , pp. 20136-20145
    • Nieto, N.1    Greenwel, P.2    Friedman, S.L.3    Zhang, F.4    Dannenberg, A.J.5    Cederbaum, A.I.6
  • 53
    • 0023851736 scopus 로고
    • Characteristics of alcohol dehydrogenase in fat-storing (Ito) cells of rat liver
    • Yamauchi M, Potter JJ, Mezey E. Characteristics of alcohol dehydrogenase in fat-storing (Ito) cells of rat liver. Gastroenterology 1988; 94: 163-169
    • (1988) Gastroenterology , vol.94 , pp. 163-169
    • Yamauchi, M.1    Potter, J.J.2    Mezey, E.3
  • 54
    • 0015840893 scopus 로고
    • Induction of hepatic microsomal reduced nicotinamide adenine dinucleotide phosphate-dependent production of hydrogen peroxide by chronic prior treatment with ethanol
    • Thurman RG. Induction of hepatic microsomal reduced nicotinamide adenine dinucleotide phosphate-dependent production of hydrogen peroxide by chronic prior treatment with ethanol. Mol Pharmacol 1973; 9: 670-675
    • (1973) Mol Pharmacol , vol.9 , pp. 670-675
    • Thurman, R.G.1
  • 56
    • 0345240945 scopus 로고    scopus 로고
    • Acetaldehyde increases the activity and gene expression of urokinase type plasminogen activator in a hepatic stellate cell line
    • Rodriguez-Fragoso L, Alvarez R, Reyes-Esparza JA, Garces ME. Acetaldehyde increases the activity and gene expression of urokinase type plasminogen activator in a hepatic stellate cell line. Toxicology 1999; 137: 1-11
    • (1999) Toxicology , vol.137 , pp. 1-11
    • Rodriguez-Fragoso, L.1    Alvarez, R.2    Reyes-Esparza, J.A.3    Garces, M.E.4
  • 57
    • 0036471578 scopus 로고    scopus 로고
    • Effect of malondialdehyde-acetaldehyde-protein adducts on the protein kinase C-dependent secretion of urokinase-type plasminogen activator in hepatic stellate cells
    • Kharbanda KK, Shubert KA, Wyatt TA, Sorrell MF, Tuma DJ. Effect of malondialdehyde-acetaldehyde-protein adducts on the protein kinase C-dependent secretion of urokinase-type plasminogen activator in hepatic stellate cells. Biochem Pharmacol 2002; 63: 553-562
    • (2002) Biochem Pharmacol , vol.63 , pp. 553-562
    • Kharbanda, K.K.1    Shubert, K.A.2    Wyatt, T.A.3    Sorrell, M.F.4    Tuma, D.J.5
  • 58
    • 0027682714 scopus 로고
    • Contribution of sinusoidal endothelial liver cells to liver fibrosis: Expression of transforming growth factor-beta 1 receptors and modulation of plasmin-generating enzymes by transformng growth factor-beta 1
    • Rieder H, Armbrust T, Meyer zum Buschenfelde KH, Ramadori G. Contribution of sinusoidal endothelial liver cells to liver fibrosis: expression of transforming growth factor-beta 1 receptors and modulation of plasmin-generating enzymes by transformng growth factor-beta 1. Hepatology 1993; 18: 937-944
    • (1993) Hepatology , vol.18 , pp. 937-944
    • Rieder, H.1    Armbrust, T.2    Meyer zum Buschenfelde, K.H.3    Ramadori, G.4
  • 59
    • 0036434480 scopus 로고    scopus 로고
    • Pentoxifylline diminished acetaldehyde-induced collagen production in hepatic stellate cells by decreasing interleukin-6 expression
    • Hernandez E, Correa A, Bucio L, Souza V, Kershenobich D, Gutierrez-Ruiz MC. Pentoxifylline diminished acetaldehyde-induced collagen production in hepatic stellate cells by decreasing interleukin-6 expression. Pharmacol Res 2002; 46: 435-443
    • (2002) Pharmacol Res , vol.46 , pp. 435-443
    • Hernandez, E.1    Correa, A.2    Bucio, L.3    Souza, V.4    Kershenobich, D.5    Gutierrez-Ruiz, M.C.6
  • 62
    • 0035672819 scopus 로고    scopus 로고
    • Malondialdehyde-acetaldehyde-protein adducts increase secretion of chemokines by rat hepatic stellate cells
    • Kharbanda KK, Todero SL, Shubert KA, Sorrell MF, Tuma DJ. Malondialdehyde-acetaldehyde-protein adducts increase secretion of chemokines by rat hepatic stellate cells. Alcohol 2001; 25: 123-128
    • (2001) Alcohol , vol.25 , pp. 123-128
    • Kharbanda, K.K.1    Todero, S.L.2    Shubert, K.A.3    Sorrell, M.F.4    Tuma, D.J.5
  • 63
    • 0001309476 scopus 로고    scopus 로고
    • MAA adducts increase chemokine production and the expression of cell adhesion molecule, ICAM-1, in hepatic stellate cells
    • Kharbanda KK, Todero SL, Sorrell MF, Tuma DJ. MAA adducts increase chemokine production and the expression of cell adhesion molecule, ICAM-1, in hepatic stellate cells. Hepatology 1998; 28 (Suppl): 311A
    • (1998) Hepatology , vol.28 , Issue.SUPPL.
    • Kharbanda, K.K.1    Todero, S.L.2    Sorrell, M.F.3    Tuma, D.J.4
  • 68
    • 0036082384 scopus 로고    scopus 로고
    • Alcohol activates activator protein-1 and mitogen-activated protein kinases in rat pancreatic stellate cells
    • Masamune A, Kikuta K, Satoh M, Satoh A, Shimosegawa T. Alcohol activates activator protein-1 and mitogen-activated protein kinases in rat pancreatic stellate cells. J Pharmacol Exp Ther 2002; 302: 36-42
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 36-42
    • Masamune, A.1    Kikuta, K.2    Satoh, M.3    Satoh, A.4    Shimosegawa, T.5
  • 69
    • 0037302934 scopus 로고    scopus 로고
    • Rat pancreatic stellate cells secrete matrix metalloproteinases: Implications for extracellular matrix turnover
    • Phillips PA, McCarroll JA, Park S, Wu MJ, Pirola R, Korsten M, Wilson JS, Apte MV. Rat pancreatic stellate cells secrete matrix metalloproteinases: implications for extracellular matrix turnover. Gut 2003; 52: 275-282
    • (2003) Gut , vol.52 , pp. 275-282
    • Phillips, P.A.1    McCarroll, J.A.2    Park, S.3    Wu, M.J.4    Pirola, R.5    Korsten, M.6    Wilson, J.S.7    Apte, M.V.8
  • 70
    • 0041592595 scopus 로고    scopus 로고
    • Pancreatic stellate cell activation by ethanol and acetaldehyde: Is it mediated by the mitogen-activated protein kinase signaling pathway?
    • McCarroll JA, Phillips PA, Park S, Doherty E, Pirola RC, Wilson JS, Apte MV. Pancreatic stellate cell activation by ethanol and acetaldehyde: is it mediated by the mitogen-activated protein kinase signaling pathway? Pancreas 2003; 27: 150-160
    • (2003) Pancreas , vol.27 , pp. 150-160
    • McCarroll, J.A.1    Phillips, P.A.2    Park, S.3    Doherty, E.4    Pirola, R.C.5    Wilson, J.S.6    Apte, M.V.7
  • 71
    • 33645968395 scopus 로고    scopus 로고
    • Mechanisms of alcohol-induced hepatic fibrosis: A summary of the Ron Thurman Symposium
    • Purohit V, Brenner DA. Mechanisms of alcohol-induced hepatic fibrosis: a summary of the Ron Thurman Symposium. Hepatology 2006; 43: 872-878
    • (2006) Hepatology , vol.43 , pp. 872-878
    • Purohit, V.1    Brenner, D.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.