Aldehydes potentiate α2(I) collagen gene activity by JNK in hepatic stellate cells

Free Radical Biology and Medicine

Volumn 30, Issue 8, 2001, Pages 846-857

  Anania, Frank A ^b,c   Womack, Lawrence ^a   Jiang, Mingde ^a   Saxena, Neeraj K ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

Author keywords

Acetaldehyde; Collagen; Fibrosis; Free radicals; JNK; Malondialdehyde; Oxidative stress; Signal transduction; Stellate cells

Indexed keywords

ACETALDEHYDE; ALCOHOL; COLLAGEN TYPE 1; COLLAGEN TYPE 1 ALPHA 2; MALONALDEHYDE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EXPRESSION VECTOR; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LIPID PEROXIDATION; LIVER CELL; LIVER INJURY; MALE; METABOLITE; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STELLATE CELL; TRANSGENE;

ACETALDEHYDE; ANIMALS; CELLS, CULTURED; COLLAGEN; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER; MALE; MALONDIALDEHYDE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; PHOSPHORYLATION; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TRANSGENES;

EID: 0035871817     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00470-1     Document Type: Article

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