Toll-like receptors signaling and regulation of immune response

Progress in Biochemistry and Biophysics

Volumn 33, Issue 9, 2006, Pages 820-827

  Wang, Hai Kun ^a   Han, Dai Shu ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Adaptive immunity; Innate immunity; Signal transduction; Toll like receptor

Indexed keywords

EID: 33751210941     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (49)

1. Janeway CA Jr. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol, 1989, 54 Pt 1, 1-13
2. Lemaitre B. The road to Toll. Nat Rev Immunol, 2004, 4 (7): 521-527
3. Takeda K, Kaisho T, Akira S. Toll-like receptors. Annu Rev Immunol, 2003, 21: 335-376
4. Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol, 2004, 4 (7): 499-511
5. O'Neill L A. TLRs: Professor Mechnikov, sit on your hat. Trends Immunol, 2004, 25 (12): 687-693
6. Hacker H, Redecke V, Blagoev B, et al. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature, 2006, 439 (7073): 204-207
7. Adachi O, Kawai T, Takeda K, et al. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity. 1998, 9(1): 143-150
8. Liew F Y, Xu D, Brint E K, et al. Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol, 2005, 5 (6): 446-458
9. Kaisho T, Akira S. Toll-like receptor function and signaling. J Allergy Clin Immunol, 2006, 117 (5): 979-987
10. Kawai T, Adachi O, Ogawa T, et al. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity, 1999, 11(1): 115-122
11. Kawai T, Akira S. TLR signaling. Cell Death Differ, 2006, 13 (5): 816-825
12. Divanovic S, Trompette A, Atabani S F, et al. Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nat Immunol, 2005, 6 (6): 571-578
13. Mansell A, Smith R, Doyle S L, et al. Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation. Nat Immunol, 2006, 7 (2): 148-155
14. Wang Y, Tang Y, Teng L, et al. Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling. Nat Immunol, 2006, 7 (2): 139-147
15. Hayashi F, Means T K, Luster A D. Toll-like receptors stimulate human neutrophil function. Blood, 2003, 102 (7): 2660-2669
16. Hornung V, Rothenfusser S, Britsch S, et al. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol, 2002, 168 (9): 4531-4537
17. Nagase H, Okugawa S, Ota Y, et al. Expression and function of Toll-like receptors in eosinophils: activation by Toll-like receptor 7 ligand. J Immunol, 2003, 171 (8): 3977-3982
18. Zarember K A, Godowski P J. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol, 2002, 168 (2): 554-561
19. Lund J, Sato A, Akira S, et al. Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells. J Exp Med, 2003, 198 (3): 513-520
20. Diebold S S, Kaisho T, Hemmi H, et al. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science, 2004, 303 (5663): 1529-1531
21. Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol, 2004, 5 (10): 987-995
22. Huang Q, Liu D, Majewski P, et al. The plasticity of dendritic cell responses to pathogens and their components. Science, 2001, 294 (5543): 870-875
23. Mantovani A. The chemokine system: redundancy for robust outputs. Immunol Today, 1999, 20 (6): 254-257
24. Doyle S E, O'Connell R M, Miranda G A, et al. Toll-like receptors induce a phagocytic gene program through p38. J Exp Med, 2004, 199 (1): 81-90
25. Blander J M, Medzhitov R. Regulation of phagosome maturation by signals from toll-like receptors. Science, 2004, 304 (5673): 1014-1018
26. Thoma-Uszynski S, Stenger S, Takeuchi O, et al. Induction of direct antimicrobial activity through mammalian toll-like receptors. Science, 2001, 291 (5508): 1544-1547
27. Liu P T, Stenger S, Li H, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science, 2006, 311 (5768): 1770-1773
28. Ashkar A A, Bauer S, Mitchell W J, et al. Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2. J Virol, 2003, 77 (16): 8948-8956
29. Zhang D, Zhang G, Hayden M S, et al. A toll-like receptor that prevents infection by uropathogenic bacteria. Science, 2004, 303 (5663): 1522-1526
30. Zasloff M. Antimicrobial peptides of multicellular organisms. Nature, 2002, 415 (6870): 389-395
31. Ayabe T, Satchell D P, Wilson C L, et al. Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria. Nat Immunol, 2000, 1 (2): 113-118
32. Birchler T, Seibl R, Buchner K, et al. Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein. Eur J Immunol, 2001, 31 (11): 3131-3137
33. Schnare M, Barton G M, Holt A C, et al. Toll-like receptors control activation of adaptive immune responses. Nat Immunol, 2001, 2 (10): 947-950
34. Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol, 2001, 2 (8): 675-680
35. Sallusto F, Schaerli P, Loetscher P, et al. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur J Immunol, 1998, 28 (9): 2760-2769
36. Dieu M C, Vanbervliet B, Vicari A, et al. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J Exp Med, 1998, 188 (2): 373-386
37. Forster R, Schubel A, Breitfeld D, et al. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell, 1999, 99 (1): 23-33
38. Gunn M D, Kyuwa S, Tam C, et al. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J Exp Med, 1999, 189 (3): 451-460
39. Blander J M, Medzhitov R. Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature, 2006, 440 (7085): 808-812
40. + T cell-mediated suppression by dendritic cells. Science, 2003, 299 (5609): 1033-1036
41. Yang Y, Huang C T, Huang X, et al. Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. Nat Immunol, 2004, 5 (5): 508-515
42. Pasare C, Medzhitov R. Control of B-cell responses by Toll-like receptors. Nature, 2005, 438 (7066): 364-368
43. Hoshino K, Kaisho T, Iwabe T, et al. Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation. Int Immunol, 2002, 14 (10): 1225-1231
44. Hoebe K, Janssen E M, Kim S O, et al. Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat Immunol, 2003, 4(12): 1223-1229
45. Colonna M, Trinchieri G, Liu Y J. Plasmacytoid dendritic cells in immunity. Nat Immunol, 2004, 5 (12): 1219-1226
46. Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol, 2003, 3 (2): 133-146
47. Pulendran B, Kumar P, Cutler C W, et al. Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo. J Immunol, 2001, 167 (9): 5067-5076
48. Kaisho T, Hoshino K, Iwabe T, et al. Endotoxin can induce MyD88-deficient dendritic cells to support T(h)2 cell differentiation. Int Immunol, 2002, 14 (7): 695-700
49. Eisenbarth S C, Piggott D A, Huleatt J W, et al. Lipopolysaccharide- enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med, 2002, 196(12): 1645-1651