-
1
-
-
0035997222
-
Beta-amyloid (Abeta) protein in cerebrospinal fluid as a biomarker for Alzheimer's disease
-
N. Andreasen, and K. Blennow Beta-amyloid (Abeta) protein in cerebrospinal fluid as a biomarker for Alzheimer's disease Peptides 23 2002 1205 1214
-
(2002)
Peptides
, vol.23
, pp. 1205-1214
-
-
Andreasen, N.1
Blennow, K.2
-
2
-
-
0032857103
-
Cerebrospinal fluid tau and Abeta42 as predictors of development of Alzheimer's disease in patients with mild cognitive impairment
-
N. Andreasen, L. Minthon, E. Vanmechelen, H. Vanderstichele, P. Davidsson, B. Winblad, and K. Blennow Cerebrospinal fluid tau and Abeta42 as predictors of development of Alzheimer's disease in patients with mild cognitive impairment Neurosci. Lett. 273 1999 5 8
-
(1999)
Neurosci. Lett.
, vol.273
, pp. 5-8
-
-
Andreasen, N.1
Minthon, L.2
Vanmechelen, E.3
Vanderstichele, H.4
Davidsson, P.5
Winblad, B.6
Blennow, K.7
-
3
-
-
0033061647
-
Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: Differences between early- and late-onset Alzheimer disease and stability during the course of disease
-
N. Andreasen, C. Hesse, P. Davidsson, L. Minthon, A. Wallin, B. Winblad, H. Vanderstichele, E. Vanmechelen, and K. Blennow Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease Arch. Neurol. 56 1999 673 680
-
(1999)
Arch. Neurol.
, vol.56
, pp. 673-680
-
-
Andreasen, N.1
Hesse, C.2
Davidsson, P.3
Minthon, L.4
Wallin, A.5
Winblad, B.6
Vanderstichele, H.7
Vanmechelen, E.8
Blennow, K.9
-
4
-
-
0030499678
-
A vector for expressing foreign genes in the brains and hearts of transgenic mice
-
D.R. Borchelt, J. Davis, M. Fischer, M.K. Lee, H.H. Slunt, T. Ratovitsky, J. Regard, N.G. Copeland, N.A. Jenkins, S.S. Sisodia, and D.L. Price A vector for expressing foreign genes in the brains and hearts of transgenic mice Genet. Anal. 13 1996 159 163
-
(1996)
Genet. Anal.
, vol.13
, pp. 159-163
-
-
Borchelt, D.R.1
Davis, J.2
Fischer, M.3
Lee, M.K.4
Slunt, H.H.5
Ratovitsky, T.6
Regard, J.7
Copeland, N.G.8
Jenkins, N.A.9
Sisodia, S.S.10
Price, D.L.11
-
5
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
D.R. Borchelt, T. Ratovitski, J. van Lare, M.K. Lee, V. Gonzales, N.A. Jenkins, N.G. Copeland, D.L. Price, and S.S. Sisodia Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins Neuron 19 1997 939 945
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
6
-
-
13044265226
-
Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid
-
M.E. Calhoun, P. Burgermeister, A.L. Phinney, M. Stalder, M. Tolnay, K.H. Wiederhold, D. Abramowski, C. Sturchler-Pierrat, B. Sommer, M. Staufenbiel, and M. Jucker Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid Proc. Natl. Acad. Sci. U. S. A. 96 1999 14088 14093
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 14088-14093
-
-
Calhoun, M.E.1
Burgermeister, P.2
Phinney, A.L.3
Stalder, M.4
Tolnay, M.5
Wiederhold, K.H.6
Abramowski, D.7
Sturchler-Pierrat, C.8
Sommer, B.9
Staufenbiel, M.10
Jucker, M.11
-
7
-
-
0031902295
-
Alzheimer's disease: Etiologies, pathophysiology, cognitive reserve, and treatment opportunities
-
J.L. Cummings, H.V. Vinters, G.M. Cole, and Z.S. Khachaturian Alzheimer's disease: etiologies, pathophysiology, cognitive reserve, and treatment opportunities Neurology 51 1998 S2 17 (discussion S65-17)
-
(1998)
Neurology
, vol.51
-
-
Cummings, J.L.1
Vinters, H.V.2
Cole, G.M.3
Khachaturian, Z.S.4
-
8
-
-
0036319503
-
Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease
-
R.B. DeMattos, K.R. Bales, M. Parsadanian, M.A. O'Dell, E.M. Foss, S.M. Paul, and D.M. Holtzman Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease J. Neurochem. 81 2002 229 236
-
(2002)
J. Neurochem.
, vol.81
, pp. 229-236
-
-
Demattos, R.B.1
Bales, K.R.2
Parsadanian, M.3
O'Dell, M.A.4
Foss, E.M.5
Paul, S.M.6
Holtzman, D.M.7
-
9
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
J. Hardy, and D.J. Selkoe The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics Science 297 2002 353 356
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
10
-
-
0030000603
-
The consortium to establish a registry for Alzheimer's disease (CERAD). Part XIV: Demographic and clinical predictors of survival in patients with Alzheimer's disease
-
A. Heyman, B. Peterson, G. Fillenbaum, and C. Pieper The consortium to establish a registry for Alzheimer's disease (CERAD). Part XIV: demographic and clinical predictors of survival in patients with Alzheimer's disease Neurology 46 1996 656 660
-
(1996)
Neurology
, vol.46
, pp. 656-660
-
-
Heyman, A.1
Peterson, B.2
Fillenbaum, G.3
Pieper, C.4
-
11
-
-
0037038814
-
Abeta immunization and anti-Abeta antibodies: Potential therapies for the prevention and treatment of Alzheimer's disease
-
D.M. Holtzman, K.R. Bales, S.M. Paul, and R.B. DeMattos Abeta immunization and anti-Abeta antibodies: potential therapies for the prevention and treatment of Alzheimer's disease Adv. Drug Deliv. Rev. 54 2002 1603 1613
-
(2002)
Adv. Drug Deliv. Rev.
, vol.54
, pp. 1603-1613
-
-
Holtzman, D.M.1
Bales, K.R.2
Paul, S.M.3
Demattos, R.B.4
-
12
-
-
1642555780
-
Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: Evidence for augmentation of a 42-specific gamma secretase
-
J.L. Jankowsky, D.J. Fadale, J. Anderson, G.M. Xu, V. Gonzales, N.A. Jenkins, N.G. Copeland, M.K. Lee, L.H. Younkin, S.L. Wagner, S.G. Younkin, and D.R. Borchelt Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase Hum. Mol. Genet. 13 2004 159 170
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 159-170
-
-
Jankowsky, J.L.1
Fadale, D.J.2
Anderson, J.3
Xu, G.M.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Lee, M.K.8
Younkin, L.H.9
Wagner, S.L.10
Younkin, S.G.11
Borchelt, D.R.12
-
13
-
-
0034837627
-
Transgenic mouse models of Alzheimer's disease
-
C. Janus, and D. Westaway Transgenic mouse models of Alzheimer's disease Physiol. Behav. 73 2001 873 886
-
(2001)
Physiol. Behav.
, vol.73
, pp. 873-886
-
-
Janus, C.1
Westaway, D.2
-
14
-
-
0345291176
-
Cerebrospinal fluid a beta42 is increased early in sporadic Alzheimer's disease and declines with disease progression
-
M. Jensen, J. Schroder, M. Blomberg, B. Engvall, J. Pantel, N. Ida, H. Basun, L.O. Wahlund, E. Werle, M. Jauss, K. Beyreuther, L. Lannfelt, and T. Hartmann Cerebrospinal fluid A beta42 is increased early in sporadic Alzheimer's disease and declines with disease progression Ann. Neurol. 45 1999 504 511
-
(1999)
Ann. Neurol.
, vol.45
, pp. 504-511
-
-
Jensen, M.1
Schroder, J.2
Blomberg, M.3
Engvall, B.4
Pantel, J.5
Ida, N.6
Basun, H.7
Wahlund, L.O.8
Werle, E.9
Jauss, M.10
Beyreuther, K.11
Lannfelt, L.12
Hartmann, T.13
-
15
-
-
0031020909
-
Amyloid precursor protein processing and a beta42 deposition in a transgenic mouse model of Alzheimer disease
-
K. Johnson-Wood, M. Lee, R. Motter, K. Hu, G. Gordon, R. Barbour, K. Khan, M. Gordon, H. Tan, D. Games, I. Lieberburg, D. Schenk, P. Seubert, and L. McConlogue Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease Proc. Natl. Acad. Sci. U. S. A. 94 1997 1550 1555
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 1550-1555
-
-
Johnson-Wood, K.1
Lee, M.2
Motter, R.3
Hu, K.4
Gordon, G.5
Barbour, R.6
Khan, K.7
Gordon, M.8
Tan, H.9
Games, D.10
Lieberburg, I.11
Schenk, D.12
Seubert, P.13
McConlogue, L.14
-
16
-
-
0035863055
-
Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease
-
T. Kawarabayashi, L.H. Younkin, T.C. Saido, M. Shoji, K.H. Ashe, and S.G. Younkin Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease J. Neurosci. 21 2001 372 381
-
(2001)
J. Neurosci.
, vol.21
, pp. 372-381
-
-
Kawarabayashi, T.1
Younkin, L.H.2
Saido, T.C.3
Shoji, M.4
Ashe, K.H.5
Younkin, S.G.6
-
17
-
-
0035147098
-
The load and distribution of beta-amyloid in brain tissue of patients with Alzheimer's disease
-
M. Kraszpulski, H. Soininen, S. Helisalmi, and I. Alafuzoff The load and distribution of beta-amyloid in brain tissue of patients with Alzheimer's disease Acta Neurol. Scand. 103 2001 88 92
-
(2001)
Acta Neurol. Scand.
, vol.103
, pp. 88-92
-
-
Kraszpulski, M.1
Soininen, H.2
Helisalmi, S.3
Alafuzoff, I.4
-
18
-
-
0032033833
-
Biochemical diagnostic markers to detect early Alzheimer's disease
-
L. Lannfelt Biochemical diagnostic markers to detect early Alzheimer's disease Neurobiol. Aging 19 1998 165 167
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 165-167
-
-
Lannfelt, L.1
-
19
-
-
0028971443
-
Amyloid beta-peptide in cerebrospinal fluid in individuals with the Swedish Alzheimer amyloid precursor protein mutation
-
L. Lannfelt, H. Basun, C. Vigo-Pelfrey, L.O. Wahlund, B. Winblad, I. Lieberburg, and D. Schenk Amyloid beta-peptide in cerebrospinal fluid in individuals with the Swedish Alzheimer amyloid precursor protein mutation Neurosci. Lett. 199 1995 203 206
-
(1995)
Neurosci. Lett.
, vol.199
, pp. 203-206
-
-
Lannfelt, L.1
Basun, H.2
Vigo-Pelfrey, C.3
Wahlund, L.O.4
Winblad, B.5
Lieberburg, I.6
Schenk, D.7
-
20
-
-
0036433445
-
Fimbria-fornix lesion does not affect APP levels and amyloid deposition in the hippocampus of APP+PS1 double transgenic mice
-
L. Liu, S. Ikonen, T. Tapiola, H. Tanila, and T. van Groen Fimbria-fornix lesion does not affect APP levels and amyloid deposition in the hippocampus of APP+PS1 double transgenic mice Exp. Neurol. 177 2002 565 574
-
(2002)
Exp. Neurol.
, vol.177
, pp. 565-574
-
-
Liu, L.1
Ikonen, S.2
Tapiola, T.3
Tanila, H.4
Van Groen, T.5
-
21
-
-
0036174969
-
The effects of long-term treatment with metrifonate, a cholinesterase inhibitor, on cholinergic activity, amyloid pathology, and cognitive function in APP and PS1 doubly transgenic mice
-
L. Liu, S. Ikonen, T. Heikkinen, T. Tapiola, T. van Groen, and H. Tanila The effects of long-term treatment with metrifonate, a cholinesterase inhibitor, on cholinergic activity, amyloid pathology, and cognitive function in APP and PS1 doubly transgenic mice Exp. Neurol. 173 2002 196 204
-
(2002)
Exp. Neurol.
, vol.173
, pp. 196-204
-
-
Liu, L.1
Ikonen, S.2
Heikkinen, T.3
Tapiola, T.4
Van Groen, T.5
Tanila, H.6
-
22
-
-
0037454478
-
Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice
-
L. Liu, T. Tapiola, S.K. Herukka, M. Heikkila, and H. Tanila Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice NeuroReport 14 2003 163 166
-
(2003)
NeuroReport
, vol.14
, pp. 163-166
-
-
Liu, L.1
Tapiola, T.2
Herukka, S.K.3
Heikkila, M.4
Tanila, H.5
-
23
-
-
0035693097
-
Cerebrospinal fluid amyloid beta(1-42) levels in the mild cognitive impairment stage of Alzheimer's disease
-
M. Maruyama, H. Arai, M. Sugita, H. Tanji, M. Higuchi, N. Okamura, T. Matsui, S. Higuchi, S. Matsushita, H. Yoshida, and H. Sasaki Cerebrospinal fluid amyloid beta(1-42) levels in the mild cognitive impairment stage of Alzheimer's disease Exp. Neurol. 172 2001 433 436
-
(2001)
Exp. Neurol.
, vol.172
, pp. 433-436
-
-
Maruyama, M.1
Arai, H.2
Sugita, M.3
Tanji, H.4
Higuchi, M.5
Okamura, N.6
Matsui, T.7
Higuchi, S.8
Matsushita, S.9
Yoshida, H.10
Sasaki, H.11
-
24
-
-
0030966462
-
A new technique: Serial puncture of the cisterna magna for obtaining cerebrospinal fluid in the mouse-application in a model of herpes simplex virus encephalitis
-
U. Meyding-Lamade, K. Ehrhart, H.L. de Ruiz, R. Kehm, and W. Lamade A new technique: serial puncture of the cisterna magna for obtaining cerebrospinal fluid in the mouse-application in a model of herpes simplex virus encephalitis J. Exp. Anim. Sci. 38 1996 77 81
-
(1996)
J. Exp. Anim. Sci.
, vol.38
, pp. 77-81
-
-
Meyding-Lamade, U.1
Ehrhart, K.2
De Ruiz, H.L.3
Kehm, R.4
Lamade, W.5
-
25
-
-
0031871740
-
Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy
-
M. Pitschke, R. Prior, M. Haupt, and D. Riesner Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy Nat. Med. 4 1998 832 834
-
(1998)
Nat. Med.
, vol.4
, pp. 832-834
-
-
Pitschke, M.1
Prior, R.2
Haupt, M.3
Riesner, D.4
-
26
-
-
0031921466
-
Mutant genes in familial Alzheimer's disease and transgenic models
-
D.L. Price, and S.S. Sisodia Mutant genes in familial Alzheimer's disease and transgenic models Annu. Rev. Neurosci. 21 1998 479 505
-
(1998)
Annu. Rev. Neurosci.
, vol.21
, pp. 479-505
-
-
Price, D.L.1
Sisodia, S.S.2
-
27
-
-
0036235633
-
Hippocampal a beta 42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice
-
J. Puolivali, J. Wang, T. Heikkinen, M. Heikkila, T. Tapiola, T. van Groen, and H. Tanila Hippocampal A beta 42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice Neurobiol. Dis. 9 2002 339 347
-
(2002)
Neurobiol. Dis.
, vol.9
, pp. 339-347
-
-
Puolivali, J.1
Wang, J.2
Heikkinen, T.3
Heikkila, M.4
Tapiola, T.5
Van Groen, T.6
Tanila, H.7
-
28
-
-
0036846604
-
Cerebrospinal fluid tau and beta-amyloid 42 proteins identify Alzheimer disease in subjects with mild cognitive impairment
-
M. Riemenschneider, N. Lautenschlager, S. Wagenpfeil, J. Diehl, A. Drzezga, and A. Kurz Cerebrospinal fluid tau and beta-amyloid 42 proteins identify Alzheimer disease in subjects with mild cognitive impairment Arch. Neurol. 59 2002 1729 1734
-
(2002)
Arch. Neurol.
, vol.59
, pp. 1729-1734
-
-
Riemenschneider, M.1
Lautenschlager, N.2
Wagenpfeil, S.3
Diehl, J.4
Drzezga, A.5
Kurz, A.6
-
29
-
-
0022401271
-
Quantitative morphology and regional and laminar distributions of senile plaques in Alzheimer's disease
-
J. Rogers, and J.H. Morrison Quantitative morphology and regional and laminar distributions of senile plaques in Alzheimer's disease J. Neurosci. 5 1985 2801 2808
-
(1985)
J. Neurosci.
, vol.5
, pp. 2801-2808
-
-
Rogers, J.1
Morrison, J.H.2
-
30
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
D.J. Selkoe Alzheimer's disease: genes, proteins, and therapy Physiol. Rev. 81 2001 741 766
-
(2001)
Physiol. Rev.
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
31
-
-
0037986691
-
Advances in the detection of Alzheimer's disease-use of cerebrospinal fluid biomarkers
-
M. Sjogren, N. Andreasen, and K. Blennow Advances in the detection of Alzheimer's disease-use of cerebrospinal fluid biomarkers Clin. Chim. Acta 332 2003 1 10
-
(2003)
Clin. Chim. Acta
, vol.332
, pp. 1-10
-
-
Sjogren, M.1
Andreasen, N.2
Blennow, K.3
-
32
-
-
0036250622
-
Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid
-
C.E. Teunissen, J. de Vente, H.W. Steinbusch, and C. De Bruijn Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid Neurobiol. Aging 23 2002 485 508
-
(2002)
Neurobiol. Aging
, vol.23
, pp. 485-508
-
-
Teunissen, C.E.1
De Vente, J.2
Steinbusch, H.W.3
De Bruijn, C.4
-
33
-
-
0037756809
-
Diffuse amyloid deposition, but not plaque number, is reduced in amyloid precursor protein/presenilin 1 double-transgenic mice by pathway lesions
-
T. van Groen, L. Liu, S. Ikonen, and I. Kadish Diffuse amyloid deposition, but not plaque number, is reduced in amyloid precursor protein/presenilin 1 double-transgenic mice by pathway lesions Neuroscience 119 2003 1185 1197
-
(2003)
Neuroscience
, vol.119
, pp. 1185-1197
-
-
Van Groen, T.1
Liu, L.2
Ikonen, S.3
Kadish, I.4
-
34
-
-
0037474039
-
Altered auditory-evoked potentials in mice carrying mutated human amyloid precursor protein and presenilin-1 transgenes
-
J. Wang, S. Ikonen, K. Gurevicius, T. Van Groen, and H. Tanila Altered auditory-evoked potentials in mice carrying mutated human amyloid precursor protein and presenilin-1 transgenes Neuroscience 116 2003 511 517
-
(2003)
Neuroscience
, vol.116
, pp. 511-517
-
-
Wang, J.1
Ikonen, S.2
Gurevicius, K.3
Van Groen, T.4
Tanila, H.5
-
35
-
-
0033801852
-
Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease
-
H.L. Weiner, C.A. Lemere, R. Maron, E.T. Spooner, T.J. Grenfell, C. Mori, S. Issazadeh, W.W. Hancock, and D.J. Selkoe Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease Ann. Neurol. 48 2000 567 579
-
(2000)
Ann. Neurol.
, vol.48
, pp. 567-579
-
-
Weiner, H.L.1
Lemere, C.A.2
Maron, R.3
Spooner, E.T.4
Grenfell, T.J.5
Mori, C.6
Issazadeh, S.7
Hancock, W.W.8
Selkoe, D.J.9
|