메뉴 건너뛰기




Volumn 64, Issue 6, 2006, Pages 609-622

Decreased expression of VEGF-A in rat experimental autoimmune encephalomyelitis and in cerebrospinal fluid mononuclear cells from patients with multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; VASCULOTROPIN A; VASCULOTROPIN B; VASCULOTROPIN RECEPTOR;

EID: 33750688816     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2006.01851.x     Document Type: Article
Times cited : (38)

References (81)
  • 1
    • 0343920277 scopus 로고    scopus 로고
    • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    • Carmeliet P, Ferreira V, Breier G et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996;380:435-9.
    • (1996) Nature , vol.380 , pp. 435-439
    • Carmeliet, P.1    Ferreira, V.2    Breier, G.3
  • 2
    • 0030004485 scopus 로고    scopus 로고
    • Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
    • Ferrara N, Carver-Moore K, Chen H et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 1996;380:439-42.
    • (1996) Nature , vol.380 , pp. 439-442
    • Ferrara, N.1    Carver-Moore, K.2    Chen, H.3
  • 3
    • 0032931234 scopus 로고    scopus 로고
    • VEGF is required for growth and survival in neonatal mice
    • Gerber HP, Hillan KJ, Ryan AM et al. VEGF is required for growth and survival in neonatal mice. Development 1999;126:1149-59.
    • (1999) Development , vol.126 , pp. 1149-1159
    • Gerber, H.P.1    Hillan, K.J.2    Ryan, A.M.3
  • 4
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003;9:669-76.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 6
    • 0029103274 scopus 로고
    • Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer
    • Liu Y, Cox SR, Morita T, Kourembanas S. Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer. Circ Res 1995;77:638-43.
    • (1995) Circ Res , vol.77 , pp. 638-643
    • Liu, Y.1    Cox, S.R.2    Morita, T.3    Kourembanas, S.4
  • 7
    • 0025688912 scopus 로고
    • Vascular permeability factor: A tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration
    • Clauss M, Gerlach M, Gerlach H et al. Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med 1990;172:1535-45.
    • (1990) J Exp Med , vol.172 , pp. 1535-1545
    • Clauss, M.1    Gerlach, M.2    Gerlach, H.3
  • 8
    • 0033653221 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) stimulates monocyte migration through endothelial monolayers via increased integrin expression
    • Heil M, Clauss M, Suzuki K et al. Vascular endothelial growth factor (VEGF) stimulates monocyte migration through endothelial monolayers via increased integrin expression. Eur J Cell Biol 2000;79:850-7.
    • (2000) Eur J Cell Biol , vol.79 , pp. 850-857
    • Heil, M.1    Clauss, M.2    Suzuki, K.3
  • 9
    • 0346690400 scopus 로고    scopus 로고
    • Proinflammatory functions of vascular endothelial growth factor in alloimmunity
    • Reinders ME, Sho M, Izawa A et al. Proinflammatory functions of vascular endothelial growth factor in alloimmunity. J Clin Invest 2003;112:1655-65.
    • (2003) J Clin Invest , vol.112 , pp. 1655-1665
    • Reinders, M.E.1    Sho, M.2    Izawa, A.3
  • 10
    • 2342667380 scopus 로고    scopus 로고
    • VEGF-mediated inflammation precedes angiogenesis in adult brain
    • Croll SD, Ransohoff RM, Cai N et al. VEGF-mediated inflammation precedes angiogenesis in adult brain. Exp Neurol 2004;187:388-402.
    • (2004) Exp Neurol , vol.187 , pp. 388-402
    • Croll, S.D.1    Ransohoff, R.M.2    Cai, N.3
  • 11
    • 0032991449 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) modulates vascular permeability and inflammation in rat brain
    • Proescholdt MA, Heiss JD, Walbridge S et al. Vascular endothelial growth factor (VEGF) modulates vascular permeability and inflammation in rat brain. J Neuropathol Exp Neurol 1999;58:613-27.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 613-627
    • Proescholdt, M.A.1    Heiss, J.D.2    Walbridge, S.3
  • 12
    • 2342667384 scopus 로고    scopus 로고
    • New roles for VEGF in nervous tissue - Beyond blood vessels
    • Rosenstein JM, Krum JM. New roles for VEGF in nervous tissue - beyond blood vessels. Exp Neurol 2004;187:246-53.
    • (2004) Exp Neurol , vol.187 , pp. 246-253
    • Rosenstein, J.M.1    Krum, J.M.2
  • 13
    • 0142116387 scopus 로고    scopus 로고
    • VEGF165 therapy exacerbates secondary damage following spinal cord injury
    • Benton RL, Whittemore SR. VEGF165 therapy exacerbates secondary damage following spinal cord injury. Neurochem Res 2003;28:1693-703.
    • (2003) Neurochem Res , vol.28 , pp. 1693-1703
    • Benton, R.L.1    Whittemore, S.R.2
  • 14
    • 0042133340 scopus 로고    scopus 로고
    • Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury
    • Widenfalk J, Lipson A, Jubran M et al. Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury. Neuroscience 2003;120:951-60.
    • (2003) Neuroscience , vol.120 , pp. 951-960
    • Widenfalk, J.1    Lipson, A.2    Jubran, M.3
  • 15
    • 0036205888 scopus 로고    scopus 로고
    • Correlation of VEGF and angiopoietin expression with disruption of blood-brain barrier and angiogenesis after focal cerebral ischemia
    • Zhang ZG, Zhang L, Tsang W et al. Correlation of VEGF and angiopoietin expression with disruption of blood-brain barrier and angiogenesis after focal cerebral ischemia. J Cereb Blood Flow Metab 2002;22:379-92.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 379-392
    • Zhang, Z.G.1    Zhang, L.2    Tsang, W.3
  • 16
    • 0041903805 scopus 로고    scopus 로고
    • VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
    • Lambrechts D, Storkebaum E, Morimoto M et al. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat Genet 2003;34:383-94.
    • (2003) Nat Genet , vol.34 , pp. 383-394
    • Lambrechts, D.1    Storkebaum, E.2    Morimoto, M.3
  • 17
    • 0034978562 scopus 로고    scopus 로고
    • Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
    • Oosthuyse B, Moons L, Storkebaum E et al. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat Genet 2001;28:131-8.
    • (2001) Nat Genet , vol.28 , pp. 131-138
    • Oosthuyse, B.1    Moons, L.2    Storkebaum, E.3
  • 18
    • 0035062394 scopus 로고    scopus 로고
    • The splice variants of vascular endothelial growth factor (VEGF) and their receptors
    • Robinson CJ, Stringer SE. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J Cell Sci 2001;114:853-65.
    • (2001) J Cell Sci , vol.114 , pp. 853-865
    • Robinson, C.J.1    Stringer, S.E.2
  • 19
    • 0242636164 scopus 로고    scopus 로고
    • Growing and shaping the vascular tree: Multiple roles for VEGF
    • Ruhrberg C. Growing and shaping the vascular tree: multiple roles for VEGF. Bioessays 2003;25:1052-60.
    • (2003) Bioessays , vol.25 , pp. 1052-1060
    • Ruhrberg, C.1
  • 20
    • 0034675037 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor and hypoxia-inducible factor-1 alpha by global ischemia in rat brain
    • Jin KL, Mao XO, Nagayama T, Goldsmith PC, Greenberg DA. Induction of vascular endothelial growth factor and hypoxia-inducible factor-1 alpha by global ischemia in rat brain. Neuroscience 2000;99:577-85.
    • (2000) Neuroscience , vol.99 , pp. 577-585
    • Jin, K.L.1    Mao, X.O.2    Nagayama, T.3    Goldsmith, P.C.4    Greenberg, D.A.5
  • 21
    • 0032899471 scopus 로고    scopus 로고
    • Simultaneous in vivo quantitation of vascular endothelial growth factor mRNA splice variants
    • Renner W, Pilger E. Simultaneous in vivo quantitation of vascular endothelial growth factor mRNA splice variants. J Vasc Res 1999;36:133-8.
    • (1999) J Vasc Res , vol.36 , pp. 133-138
    • Renner, W.1    Pilger, E.2
  • 22
    • 0043125643 scopus 로고    scopus 로고
    • VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization
    • Ishida S, Usui T, Yamashiro K et al. VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization. J Exp Med 2003;198:483-9.
    • (2003) J Exp Med , vol.198 , pp. 483-489
    • Ishida, S.1    Usui, T.2    Yamashiro, K.3
  • 23
    • 0942287258 scopus 로고    scopus 로고
    • VEGF164(165) as the pathological isoform: Differential leukocyte and endothelial responses through VEGFR1 and VEGFR2
    • Usui T, Ishida S, Yamashiro K et al. VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2. Invest Ophthalmol Vis Sci 2004;45:368-74.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 368-374
    • Usui, T.1    Ishida, S.2    Yamashiro, K.3
  • 24
    • 19144366076 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human gene related to vascular endothelial growth factor
    • Grimmond S, Lagercrantz J, Drinkwater C et al. Cloning and characterization of a novel human gene related to vascular endothelial growth factor. Genome Res 1996;6:124-31.
    • (1996) Genome Res , vol.6 , pp. 124-131
    • Grimmond, S.1    Lagercrantz, J.2    Drinkwater, C.3
  • 25
    • 9244227572 scopus 로고    scopus 로고
    • Vascular endothelial growth factor B, a novel growth factor for endothelial cells
    • Olofsson B, Pajusola K, Kaipainen A et al. Vascular endothelial growth factor B, a novel growth factor for endothelial cells. Proc Natl Acad Sci U S A 1996;93:2576-81.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 2576-2581
    • Olofsson, B.1    Pajusola, K.2    Kaipainen, A.3
  • 26
    • 27744471912 scopus 로고    scopus 로고
    • Transgenic overexpression of vascular endothelial growth factor-B isoforms by endothelial cells potentiates postnatal vessel growth in vivo and in vitro
    • Mould AW, Greco SA, Cahill MM et al. Transgenic overexpression of vascular endothelial growth factor-B isoforms by endothelial cells potentiates postnatal vessel growth in vivo and in vitro. Circ Res 2005;97:e60-70.
    • (2005) Circ Res , vol.97
    • Mould, A.W.1    Greco, S.A.2    Cahill, M.M.3
  • 27
    • 0035902538 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect
    • Aase K, von Euler G, Li X et al. Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect. Circulation 2001;104:358-64.
    • (2001) Circulation , vol.104 , pp. 358-364
    • Aase, K.1    Von Euler, G.2    Li, X.3
  • 28
    • 18844473540 scopus 로고    scopus 로고
    • Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia
    • Bellomo D, Headrick JP, Silins GU et al. Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia. Circ Res 2000;86:E29-35.
    • (2000) Circ Res , vol.86
    • Bellomo, D.1    Headrick, J.P.2    Silins, G.U.3
  • 29
    • 4944253249 scopus 로고    scopus 로고
    • Increased severity of cerebral ischemic injury in vascular endothelial growth factor-B-deficient mice
    • Sun Y, Jin K, Childs JT et al. Increased severity of cerebral ischemic injury in vascular endothelial growth factor-B-deficient mice. J Cereb Blood Flow Metab 2004;24:1146-52.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 1146-1152
    • Sun, Y.1    Jin, K.2    Childs, J.T.3
  • 30
    • 0141788312 scopus 로고    scopus 로고
    • Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis
    • Mould AW, Tonks ID, Cahill MM et al. Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis. Arthritis Rheum 2003;48:2660-9.
    • (2003) Arthritis Rheum , vol.48 , pp. 2660-2669
    • Mould, A.W.1    Tonks, I.D.2    Cahill, M.M.3
  • 31
    • 0036306121 scopus 로고    scopus 로고
    • Vascular growth factors and lymphangiogenesis
    • Jussila L, Alitalo K. Vascular growth factors and lymphangiogenesis. Physiol Rev 2002;82:673-700.
    • (2002) Physiol Rev , vol.82 , pp. 673-700
    • Jussila, L.1    Alitalo, K.2
  • 32
    • 0037703184 scopus 로고    scopus 로고
    • Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
    • Autiero M, Waltenberger J, Communi D et al. Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat Med 2003;9:936-43.
    • (2003) Nat Med , vol.9 , pp. 936-943
    • Autiero, M.1    Waltenberger, J.2    Communi, D.3
  • 33
    • 0038692867 scopus 로고    scopus 로고
    • VEGF-A(164/165) and PlGF: Roles in angiogenesis and arteriogenesis
    • Nagy JA, Dvorak AM, Dvorak HF. VEGF-A(164/165) and PlGF: roles in angiogenesis and arteriogenesis. Trends Cardiovasc Med 2003;13:169-75.
    • (2003) Trends Cardiovasc Med , vol.13 , pp. 169-175
    • Nagy, J.A.1    Dvorak, A.M.2    Dvorak, H.F.3
  • 34
    • 0037441439 scopus 로고    scopus 로고
    • Hypoxia-like tissue injury as a component of multiple sclerosis lesions
    • Lassmann H. Hypoxia-like tissue injury as a component of multiple sclerosis lesions. J Neurol Sci 2003;206:187-91.
    • (2003) J Neurol Sci , vol.206 , pp. 187-191
    • Lassmann, H.1
  • 35
    • 0242667881 scopus 로고    scopus 로고
    • Molecular changes in normal appearing white matter in multiple sclerosis are characteristic of neuroprotective mechanisms against hypoxic insult
    • Graumann U, Reynolds R, Steck AJ, Schaeren-Wiemers N. Molecular changes in normal appearing white matter in multiple sclerosis are characteristic of neuroprotective mechanisms against hypoxic insult. Brain Pathol 2003;13:554-73.
    • (2003) Brain Pathol , vol.13 , pp. 554-573
    • Graumann, U.1    Reynolds, R.2    Steck, A.J.3    Schaeren-Wiemers, N.4
  • 36
    • 0242574486 scopus 로고    scopus 로고
    • VEGF and vascular changes in chronic neuroinflammation
    • Kirk SL, Karlik SJ. VEGF and vascular changes in chronic neuroinflammation. J Autoimmun 2003;21:353-63.
    • (2003) J Autoimmun , vol.21 , pp. 353-363
    • Kirk, S.L.1    Karlik, S.J.2
  • 37
    • 0036794017 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is expressed in multiple sclerosis plaques and can induce inflammatory lesions in experimental allergic encephalomyelitis rats
    • Proescholdt MA, Jacobson S, Tresser N, Oldfield EH, Merrill MJ. Vascular endothelial growth factor is expressed in multiple sclerosis plaques and can induce inflammatory lesions in experimental allergic encephalomyelitis rats. J Neuropathol Exp Neurol 2002;61:914-25.
    • (2002) J Neuropathol Exp Neurol , vol.61 , pp. 914-925
    • Proescholdt, M.A.1    Jacobson, S.2    Tresser, N.3    Oldfield, E.H.4    Merrill, M.J.5
  • 38
    • 33645092394 scopus 로고    scopus 로고
    • Upregulation of vascular growth factors in multiple sclerosis: Correlation with MRI findings
    • Su JJ, Osoegawa M, Matsuoka T et al. Upregulation of vascular growth factors in multiple sclerosis: correlation with MRI findings. J Neurol Sci 2006;243:21-30.
    • (2006) J Neurol Sci , vol.243 , pp. 21-30
    • Su, J.J.1    Osoegawa, M.2    Matsuoka, T.3
  • 39
    • 0347057814 scopus 로고    scopus 로고
    • Vascular proliferation and angiogenesis in MS: Clinical and pathogenic implications
    • Ludwin S. Vascular proliferation and angiogenesis in MS: clinical and pathogenic implications. J Neuropath Exp Neurol 2001;60:505.
    • (2001) J Neuropath Exp Neurol , vol.60 , pp. 505
    • Ludwin, S.1
  • 40
    • 0027363911 scopus 로고
    • Human mesangial cells and peripheral blood mononuclear cells produce vascular permeability factor
    • Iijima K, Yoshikawa N, Connolly DT, Nakamura H. Human mesangial cells and peripheral blood mononuclear cells produce vascular permeability factor. Kidney Int 1993;44:959-66.
    • (1993) Kidney Int , vol.44 , pp. 959-966
    • Iijima, K.1    Yoshikawa, N.2    Connolly, D.T.3    Nakamura, H.4
  • 41
    • 1642348866 scopus 로고    scopus 로고
    • Angiogenesis-inflammation crosstalk: Vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization
    • Mor F, Quintana FJ, Cohen IR. Angiogenesis-inflammation crosstalk: vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization. J Immunol 2004;172:4618-23.
    • (2004) J Immunol , vol.172 , pp. 4618-4623
    • Mor, F.1    Quintana, F.J.2    Cohen, I.R.3
  • 42
    • 0035707638 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis in the rat: Lessons in T-cell immunology and autoreactivity
    • Swanborg RH. Experimental autoimmune encephalomyelitis in the rat: lessons in T-cell immunology and autoreactivity. Immunol Rev 2001;184:129-35.
    • (2001) Immunol Rev , vol.184 , pp. 129-135
    • Swanborg, R.H.1
  • 43
    • 0031985168 scopus 로고    scopus 로고
    • Molecular and genetic requirements for preferential recruitment of TCRBV8S2+ T cells in Lewis rat experimental autoimmune encephalomyelitis
    • Weissert R, Svenningsson A, Lobell A et al. Molecular and genetic requirements for preferential recruitment of TCRBV8S2+ T cells in Lewis rat experimental autoimmune encephalomyelitis. J Immunol 1998;160:681-90.
    • (1998) J Immunol , vol.160 , pp. 681-690
    • Weissert, R.1    Svenningsson, A.2    Lobell, A.3
  • 44
    • 0036226510 scopus 로고    scopus 로고
    • Differential expression of neurotrophic factors and inflammatory cytokines by myelin basic protein-specific and other recruited T cells infiltrating the central nervous system during experimental autoimmune encephalomyelitis
    • Muhallab S, Lundberg C, Gielen AW et al. Differential expression of neurotrophic factors and inflammatory cytokines by myelin basic protein-specific and other recruited T cells infiltrating the central nervous system during experimental autoimmune encephalomyelitis. Scand J Immunol 2002;55:264-73.
    • (2002) Scand J Immunol , vol.55 , pp. 264-273
    • Muhallab, S.1    Lundberg, C.2    Gielen, A.W.3
  • 45
    • 0034955141 scopus 로고    scopus 로고
    • Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis
    • McDonald WI, Compston A, Edan G et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001;50:121-7.
    • (2001) Ann Neurol , vol.50 , pp. 121-127
    • McDonald, W.I.1    Compston, A.2    Edan, G.3
  • 46
    • 2442704124 scopus 로고    scopus 로고
    • T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis
    • Khademi M, Illes Z, Gielen AW et al. T Cell Ig- and mucin-domain- containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis. J Immunol 2004;172:7169-76.
    • (2004) J Immunol , vol.172 , pp. 7169-7176
    • Khademi, M.1    Illes, Z.2    Gielen, A.W.3
  • 47
    • 9144224425 scopus 로고    scopus 로고
    • Selection and validation of endogenous reference genes using a high throughput approach
    • Jin P, Zhao Y, Ngalame Y et al. Selection and validation of endogenous reference genes using a high throughput approach. BMC Genomics 2004;5:55.
    • (2004) BMC Genomics , vol.5 , pp. 55
    • Jin, P.1    Zhao, Y.2    Ngalame, Y.3
  • 48
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J, De Preter K, Pattyn F et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002;3:RESEARCH0034.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3
  • 49
    • 0036065151 scopus 로고    scopus 로고
    • Upregulation of VEGF-A without angiogenesis in a mouse model of dilated cardiomyopathy caused by mitochondrial dysfunction
    • Tham E, Wang J, Piehl F, Weber G. Upregulation of VEGF-A without angiogenesis in a mouse model of dilated cardiomyopathy caused by mitochondrial dysfunction. J Histochem Cytochem 2002;50:935-44.
    • (2002) J Histochem Cytochem , vol.50 , pp. 935-944
    • Tham, E.1    Wang, J.2    Piehl, F.3    Weber, G.4
  • 50
    • 0033429458 scopus 로고    scopus 로고
    • Expression of nonclassical MHC class I (RT1-U) in certain neuronal populations of the central nervous system
    • Lidman O, Olsson T, Piehl F. Expression of nonclassical MHC class I (RT1-U) in certain neuronal populations of the central nervous system. Eur J Neurosci 1999;11:4468-72.
    • (1999) Eur J Neurosci , vol.11 , pp. 4468-4472
    • Lidman, O.1    Olsson, T.2    Piehl, F.3
  • 51
    • 20444444553 scopus 로고    scopus 로고
    • Expression of T cell immunoglobulin-and mucin-domain-containing molecules-1 and -3 (TIM-1 and -3) in the rat nervous and immune systems
    • Gielen AW, Lobell A, Lidman O et al. Expression of T cell immunoglobulin-and mucin-domain-containing molecules-1 and -3 (TIM-1 and -3) in the rat nervous and immune systems. J Neuroimmunol 2005;164:93-104.
    • (2005) J Neuroimmunol , vol.164 , pp. 93-104
    • Gielen, A.W.1    Lobell, A.2    Lidman, O.3
  • 53
    • 0036893519 scopus 로고    scopus 로고
    • Pulmonary hypertension in TNF-alpha-overexpressing mice is associated with decreased VEGF gene expression
    • Fujita M, Mason RJ, Cool C et al. Pulmonary hypertension in TNF-alpha-overexpressing mice is associated with decreased VEGF gene expression. J Appl Physiol 2002;93:2162-70.
    • (2002) J Appl Physiol , vol.93 , pp. 2162-2170
    • Fujita, M.1    Mason, R.J.2    Cool, C.3
  • 54
    • 0033949988 scopus 로고    scopus 로고
    • Effects of interferon-gamma on secretion of vascular endothelial growth factor by endometrial stromal cells
    • Kawano Y, Matsui N, Kamihigashi S, Narahara H, Miyakawa I. Effects of interferon-gamma on secretion of vascular endothelial growth factor by endometrial stromal cells. Am J Reprod Immunol 2000;43:47-52.
    • (2000) Am J Reprod Immunol , vol.43 , pp. 47-52
    • Kawano, Y.1    Matsui, N.2    Kamihigashi, S.3    Narahara, H.4    Miyakawa, I.5
  • 55
    • 0036616886 scopus 로고    scopus 로고
    • IL-4 and interferon-gamma differentially modulate vascular endothelial growth factor release from normal human keratinocytes and fibroblasts
    • Trompezinski S, Denis A, Vinche A, Schmitt D, Viac J. IL-4 and interferon-gamma differentially modulate vascular endothelial growth factor release from normal human keratinocytes and fibroblasts. Exp Dermatol 2002;11:224-31.
    • (2002) Exp Dermatol , vol.11 , pp. 224-231
    • Trompezinski, S.1    Denis, A.2    Vinche, A.3    Schmitt, D.4    Viac, J.5
  • 56
    • 33745021587 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality
    • Yano K, Liaw PC, Mullington JM et al. Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality. J Exp Med 2006;203:1447-58.
    • (2006) J Exp Med , vol.203 , pp. 1447-1458
    • Yano, K.1    Liaw, P.C.2    Mullington, J.M.3
  • 57
    • 33644913172 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors in the central nervous system in amyotrophic lateral sclerosis
    • Brockington A, Wharton SB, Fernando M et al. Expression of vascular endothelial growth factor and its receptors in the central nervous system in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2006;65:26-36.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 26-36
    • Brockington, A.1    Wharton, S.B.2    Fernando, M.3
  • 59
    • 0033404669 scopus 로고    scopus 로고
    • VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain
    • van Bruggen N, Thibodeaux H, Palmer JT et al. VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain. J Clin Invest 1999;104:1613-20.
    • (1999) J Clin Invest , vol.104 , pp. 1613-1620
    • Van Bruggen, N.1    Thibodeaux, H.2    Palmer, J.T.3
  • 60
    • 33646142053 scopus 로고    scopus 로고
    • Contraindications of VEGF-based therapeutic angiogenesis: Effects on macrophage density and histology of normal and ischemic brains
    • Manoonkitiwongsa PS, Schultz RL, Whitter EF, Lyden PD. Contraindications of VEGF-based therapeutic angiogenesis: effects on macrophage density and histology of normal and ischemic brains. Vascul Pharmacol 2006;44:316-25.
    • (2006) Vascul Pharmacol , vol.44 , pp. 316-325
    • Manoonkitiwongsa, P.S.1    Schultz, R.L.2    Whitter, E.F.3    Lyden, P.D.4
  • 61
    • 0029867554 scopus 로고    scopus 로고
    • Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
    • Barleon B, Sozzani S, Zhou D et al. Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 1996;87:3336-43.
    • (1996) Blood , vol.87 , pp. 3336-3343
    • Barleon, B.1    Sozzani, S.2    Zhou, D.3
  • 62
    • 0032925156 scopus 로고    scopus 로고
    • Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
    • Carmeliet P, Ng YS, Nuyens D et al. Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Nat Med 1999;5:495-502.
    • (1999) Nat Med , vol.5 , pp. 495-502
    • Carmeliet, P.1    Ng, Y.S.2    Nuyens, D.3
  • 63
    • 0037108152 scopus 로고    scopus 로고
    • Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis
    • Ruhrberg C, Gerhardt H, Golding M et al. Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis. Genes Dev 2002;16:2684-98.
    • (2002) Genes Dev , vol.16 , pp. 2684-2698
    • Ruhrberg, C.1    Gerhardt, H.2    Golding, M.3
  • 64
    • 0036174063 scopus 로고    scopus 로고
    • Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms
    • Stalmans I, Ng YS, Rohan R et al. Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms. J Clin Invest 2002;109:327-36.
    • (2002) J Clin Invest , vol.109 , pp. 327-336
    • Stalmans, I.1    Ng, Y.S.2    Rohan, R.3
  • 65
    • 4644234505 scopus 로고    scopus 로고
    • VEGF: Once regarded as a specific angiogenic factor, now implicated in neuroprotection
    • Storkebaum E, Lambrechts D, Carmeliet P. VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection. Bioessays 2004;26:943-54.
    • (2004) Bioessays , vol.26 , pp. 943-954
    • Storkebaum, E.1    Lambrechts, D.2    Carmeliet, P.3
  • 66
    • 0037716760 scopus 로고    scopus 로고
    • Inhibition of endogenous VEGF impedes revascularization and astroglial proliferation: Roles for VEGF in brain repair
    • Krum JM, Khaibullina A. Inhibition of endogenous VEGF impedes revascularization and astroglial proliferation: roles for VEGF in brain repair. Exp Neurol 2003;181:241-57.
    • (2003) Exp Neurol , vol.181 , pp. 241-257
    • Krum, J.M.1    Khaibullina, A.2
  • 67
    • 0031826273 scopus 로고    scopus 로고
    • Reduction of ischemic damage by application of vascular endothelial growth factor in rat brain after transient ischemia
    • Hayashi T, Abe K, Itoyama Y. Reduction of ischemic damage by application of vascular endothelial growth factor in rat brain after transient ischemia. J Cereb Blood Flow Metab 1998;18:887-95.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 887-895
    • Hayashi, T.1    Abe, K.2    Itoyama, Y.3
  • 68
    • 16644382257 scopus 로고    scopus 로고
    • Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
    • Storkebaum E, Lambrechts D, Dewerchin M et al. Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS. Nat Neurosci 2005;8:85-92.
    • (2005) Nat Neurosci , vol.8 , pp. 85-92
    • Storkebaum, E.1    Lambrechts, D.2    Dewerchin, M.3
  • 69
    • 2942627907 scopus 로고    scopus 로고
    • Low levels of the vascular endothelial growth factor in CSF from early ALS patients
    • Devos D, Moreau C, Lassalle P et al. Low levels of the vascular endothelial growth factor in CSF from early ALS patients. Neurology 2004;62:2127-9.
    • (2004) Neurology , vol.62 , pp. 2127-2129
    • Devos, D.1    Moreau, C.2    Lassalle, P.3
  • 70
    • 20044378293 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene variability is associated with increased risk for AD
    • Del Bo R, Scarlato M, Ghezzi S et al. Vascular endothelial growth factor gene variability is associated with increased risk for AD. Ann Neurol 2005;57:373-80.
    • (2005) Ann Neurol , vol.57 , pp. 373-380
    • Del Bo, R.1    Scarlato, M.2    Ghezzi, S.3
  • 71
    • 0035882381 scopus 로고    scopus 로고
    • Acute neuronal apoptosis in a rat model of multiple sclerosis
    • Meyer R, Weissert R, Diem R et al. Acute neuronal apoptosis in a rat model of multiple sclerosis. J Neurosci 2001;21:6214-20.
    • (2001) J Neurosci , vol.21 , pp. 6214-6220
    • Meyer, R.1    Weissert, R.2    Diem, R.3
  • 72
    • 0033963231 scopus 로고    scopus 로고
    • Autoimmune encephalomyelitis ameliorated by AMPA antagonists
    • Smith T, Groom A, Zhu B, Turski L. Autoimmune encephalomyelitis ameliorated by AMPA antagonists. Nat Med 2000;6:62-6.
    • (2000) Nat Med , vol.6 , pp. 62-66
    • Smith, T.1    Groom, A.2    Zhu, B.3    Turski, L.4
  • 73
    • 0035166271 scopus 로고    scopus 로고
    • Evidence of axonal damage in the early stages of multiple sclerosis and its relevance to disability
    • De Stefano N, Narayanan S, Francis GS et al. Evidence of axonal damage in the early stages of multiple sclerosis and its relevance to disability. Arch Neurol 2001;58:65-70.
    • (2001) Arch Neurol , vol.58 , pp. 65-70
    • De Stefano, N.1    Narayanan, S.2    Francis, G.S.3
  • 74
    • 21544476476 scopus 로고    scopus 로고
    • Association of the HLA region with multiple sclerosis as confirmed by a genome screen using <10,000 SNPs on DNA chips
    • Godde R, Rohde K, Becker C et al. Association of the HLA region with multiple sclerosis as confirmed by a genome screen using <10,000 SNPs on DNA chips. J Mol Med 2005;83:486-94.
    • (2005) J Mol Med , vol.83 , pp. 486-494
    • Godde, R.1    Rohde, K.2    Becker, C.3
  • 75
    • 27144538977 scopus 로고    scopus 로고
    • A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis
    • Lincoln MR, Montpetit A, Cader MZ et al. A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis. Nat Genet 2005;37:1108-12.
    • (2005) Nat Genet , vol.37 , pp. 1108-1112
    • Lincoln, M.R.1    Montpetit, A.2    Cader, M.Z.3
  • 76
    • 0032537456 scopus 로고    scopus 로고
    • A comparative study of the expression patterns for VEGF, VEGF-B/VRF and VEGF-C in the developing and adult mouse
    • Lagercrantz J, Farnebo F, Larsson C et al. A comparative study of the expression patterns for VEGF, VEGF-B/VRF and VEGF-C in the developing and adult mouse. Biochim Biophys Acta 1998;1398:157-63.
    • (1998) Biochim Biophys Acta , vol.1398 , pp. 157-163
    • Lagercrantz, J.1    Farnebo, F.2    Larsson, C.3
  • 77
    • 19244379078 scopus 로고    scopus 로고
    • Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
    • Carmeliet P, Moons L, Luttun A et al. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med 2001;7:575-83.
    • (2001) Nat Med , vol.7 , pp. 575-583
    • Carmeliet, P.1    Moons, L.2    Luttun, A.3
  • 78
    • 0029745025 scopus 로고    scopus 로고
    • VEGF and flt. Expression time kinetics in rat brain infarct
    • discussion 72-3
    • Kovacs Z, Ikezaki K, Samoto K, Inamura T, Fukui M. VEGF and flt. Expression time kinetics in rat brain infarct. Stroke 1996;27:1865-72; discussion 72-3.
    • (1996) Stroke , vol.27 , pp. 1865-1872
    • Kovacs, Z.1    Ikezaki, K.2    Samoto, K.3    Inamura, T.4    Fukui, M.5
  • 79
    • 0028123770 scopus 로고
    • Monoclonal antibody to murine PECAM-1 (CD31) blocks acute inflammation in vivo
    • Bogen S, Pak J, Garifallou M, Deng X, Muller WA. Monoclonal antibody to murine PECAM-1 (CD31) blocks acute inflammation in vivo. J Exp Med 1994;179:1059-64.
    • (1994) J Exp Med , vol.179 , pp. 1059-1064
    • Bogen, S.1    Pak, J.2    Garifallou, M.3    Deng, X.4    Muller, W.A.5
  • 80
    • 0027248750 scopus 로고
    • PECAM-1 is required for transendothelial migration of leukocytes
    • Muller WA, Weigl SA, Deng X, Phillips DM. PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med 1993;178:449-60.
    • (1993) J Exp Med , vol.178 , pp. 449-460
    • Muller, W.A.1    Weigl, S.A.2    Deng, X.3    Phillips, D.M.4
  • 81
    • 0036167828 scopus 로고    scopus 로고
    • Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice
    • Graesser D, Solowiej A, Bruckner M et al. Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice. J Clin Invest 2002;109:383-92.
    • (2002) J Clin Invest , vol.109 , pp. 383-392
    • Graesser, D.1    Solowiej, A.2    Bruckner, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.