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Volumn 65, Issue 1, 2006, Pages 26-36

Expression of vascular endothelial growth factor and its receptors in the central nervous system in amyotrophic lateral sclerosis

Author keywords

Amyotrophic lateral sclerosis (ALS); Immunohistochemistry; Motor neuron disease (MND); Neuropilin 1 (NRP1); Vascular endothelial growth factor (VEGF); VEGF receptor 2 (VEGFR2)

Indexed keywords

NEUROPILIN 1; SYNAPTOPHYSIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; VASCULOTROPIN; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN A;

EID: 33644913172     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.jnen.0000196134.51217.74     Document Type: Article
Times cited : (86)

References (32)
  • 1
    • 0028001606 scopus 로고
    • Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
    • Figlewicz DA, Krizus A, Martinoli MG, et al. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Hum Mol Genet 1994;3:1757-61
    • (1994) Hum Mol Genet , vol.3 , pp. 1757-1761
    • Figlewicz, D.A.1    Krizus, A.2    Martinoli, M.G.3
  • 2
    • 0037382240 scopus 로고    scopus 로고
    • Mutant dynactin in motor neuron disease
    • Puls I, Jonnakuty C, LaMonte BH, et al. Mutant dynactin in motor neuron disease. Nat Genet 2003;33:455-56
    • (2003) Nat Genet , vol.33 , pp. 455-456
    • Puls, I.1    Jonnakuty, C.2    LaMonte, B.H.3
  • 3
    • 0034785483 scopus 로고    scopus 로고
    • A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
    • Hadano S, Hand CK, Osuga H, et al. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat Genet 2001;29:166-73
    • (2001) Nat Genet , vol.29 , pp. 166-173
    • Hadano, S.1    Hand, C.K.2    Osuga, H.3
  • 4
    • 0034785509 scopus 로고    scopus 로고
    • The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
    • Yang Y, Hentati A, Deng HX, et al. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nat Genet 2001;29:160-65
    • (2001) Nat Genet , vol.29 , pp. 160-165
    • Yang, Y.1    Hentati, A.2    Deng, H.X.3
  • 5
    • 2442658908 scopus 로고    scopus 로고
    • DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)
    • Chen YZ, Bennett CL, Huynh HM, et al. DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4). Am J Hum Genet 2004;74:1128-35
    • (2004) Am J Hum Genet , vol.74 , pp. 1128-1135
    • Chen, Y.Z.1    Bennett, C.L.2    Huynh, H.M.3
  • 6
    • 6344257200 scopus 로고    scopus 로고
    • A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
    • Nishimura AL, Mitne-Neto M, Silva HC, et al. A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. Am J Hum Genet 2004;75:822-31
    • (2004) Am J Hum Genet , vol.75 , pp. 822-831
    • Nishimura, A.L.1    Mitne-Neto, M.2    Silva, H.C.3
  • 7
    • 23144448320 scopus 로고    scopus 로고
    • Molecular and cellular pathways of neurodegeneration in motor neurone disease
    • Shaw PJ. Molecular and cellular pathways of neurodegeneration in motor neurone disease. J Neurol Neurosurg Psychiatry 2005;76:1046-57
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 1046-1057
    • Shaw, P.J.1
  • 8
    • 3943102116 scopus 로고    scopus 로고
    • Unraveling the mechanisms involved in motor neuron degeneration in ALS
    • Bruijn LI, Miller TM, Cleveland DW. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci 2004;27:723-49
    • (2004) Annu Rev Neurosci , vol.27 , pp. 723-749
    • Bruijn, L.I.1    Miller, T.M.2    Cleveland, D.W.3
  • 9
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003;9:669-76
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 10
    • 0029039195 scopus 로고
    • Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
    • Levy AP, Levy NS, Wegner S, et al. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J Biol Chem 1995;270:13333-40
    • (1995) J Biol Chem , vol.270 , pp. 13333-13340
    • Levy, A.P.1    Levy, N.S.2    Wegner, S.3
  • 11
    • 0029103274 scopus 로고
    • Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer
    • Liu Y, Cox SR, Morita T, et al. Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer. Circ Res 1995;77:638-43
    • (1995) Circ Res , vol.77 , pp. 638-643
    • Liu, Y.1    Cox, S.R.2    Morita, T.3
  • 12
    • 0034978562 scopus 로고    scopus 로고
    • Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
    • Oosthuyse B, Moons L, Storkebaum E, et al. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat Genet 2001;28:131-38
    • (2001) Nat Genet , vol.28 , pp. 131-138
    • Oosthuyse, B.1    Moons, L.2    Storkebaum, E.3
  • 13
    • 0041903805 scopus 로고    scopus 로고
    • VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
    • Lambrechts D, Storkebaum E, Morimoto M, et al. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat Genet 2003;34:383-94
    • (2003) Nat Genet , vol.34 , pp. 383-394
    • Lambrechts, D.1    Storkebaum, E.2    Morimoto, M.3
  • 14
    • 20044384733 scopus 로고    scopus 로고
    • Screening of the regulatory and coding regions of vascular endothelial growth factor in amyotrophic lateral sclerosis
    • Brockington A, Kirby J, Eggitt D, et al. Screening of the regulatory and coding regions of vascular endothelial growth factor in amyotrophic lateral sclerosis. Neurogenetics 2004;6:101-4
    • (2004) Neurogenetics , vol.6 , pp. 101-104
    • Brockington, A.1    Kirby, J.2    Eggitt, D.3
  • 15
  • 16
    • 0032431037 scopus 로고    scopus 로고
    • Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors
    • U S A
    • Marti HH, Risau W. Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors. Proc Natl Acad Sci U S A 1998;95:15809-14
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 15809-15814
    • Marti, H.H.1    Risau, W.2
  • 17
    • 0027461981 scopus 로고
    • Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues
    • Monacci WT, Merrill MJ, Oldfield EH. Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues. Am J Physiol 1993;264:C995-C1002
    • (1993) Am J Physiol , vol.264
    • Monacci, W.T.1    Merrill, M.J.2    Oldfield, E.H.3
  • 18
    • 0141959268 scopus 로고    scopus 로고
    • Distribution of Flk-1 and Flt-1 receptors in neonatal and adult rat brains
    • Yang SZ, Zhang LM, Huang YL, et al. Distribution of Flk-1 and Flt-1 receptors in neonatal and adult rat brains. Anat Rec 2003;274A:851-56
    • (2003) Anat Rec , vol.274 A , pp. 851-856
    • Yang, S.Z.1    Zhang, L.M.2    Huang, Y.L.3
  • 19
    • 0032937146 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its receptor, KDR, in human brain tissue after ischemic stroke
    • Issa R, Krupinski J, Bujny T, et al. Vascular endothelial growth factor and its receptor, KDR, in human brain tissue after ischemic stroke. Lab Invest 1999;79:417-25
    • (1999) Lab Invest , vol.79 , pp. 417-425
    • Issa, R.1    Krupinski, J.2    Bujny, T.3
  • 20
    • 4344622781 scopus 로고    scopus 로고
    • Immunohistochemical localization of vascular endothelial growth factor receptors-1, -2 and -3 in human spinal cord: Altered expression in amyotrophic lateral sclerosis
    • Spliet WG, Aronica E, Ramkema M, et al. Immunohistochemical localization of vascular endothelial growth factor receptors-1, -2 and -3 in human spinal cord: Altered expression in amyotrophic lateral sclerosis. Neuropathol Appl Neurobiol 2004;30:351-59
    • (2004) Neuropathol Appl Neurobiol , vol.30 , pp. 351-359
    • Spliet, W.G.1    Aronica, E.2    Ramkema, M.3
  • 21
    • 0037451069 scopus 로고    scopus 로고
    • VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death
    • Li B, Xu W, Luo C, et al. VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death. Brain Res Mol Brain Res 2003;111:155-64
    • (2003) Brain Res Mol Brain Res , vol.111 , pp. 155-164
    • Li, B.1    Xu, W.2    Luo, C.3
  • 22
    • 16644382257 scopus 로고    scopus 로고
    • Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
    • Storkebaum E, Lambrechts D, Dewerchin M, et al. Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS. Nat Neurosci 2005;8:85-92
    • (2005) Nat Neurosci , vol.8 , pp. 85-92
    • Storkebaum, E.1    Lambrechts, D.2    Dewerchin, M.3
  • 23
    • 2642526164 scopus 로고    scopus 로고
    • VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model
    • Azzouz M, Ralph GS, Storkebaum E, et al. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model. Nature 2004;429:413-17
    • (2004) Nature , vol.429 , pp. 413-417
    • Azzouz, M.1    Ralph, G.S.2    Storkebaum, E.3
  • 24
    • 12144286872 scopus 로고    scopus 로고
    • Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in motor neuron degeneration
    • Sopher BL, Thomas PS, LaFevre-Bernt MA, et al. Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in motor neuron degeneration. Neuron 2004;41:687-91
    • (2004) Neuron , vol.41 , pp. 687-691
    • Sopher, B.L.1    Thomas, P.S.2    LaFevre-Bernt, M.A.3
  • 25
    • 2942627907 scopus 로고    scopus 로고
    • Low levels of the vascular endothelial growth factor in CSF from early ALS patients
    • Devos D, Moreau C, Lassalle P, et al. Low levels of the vascular endothelial growth factor in CSF from early ALS patients. Neurology 2004;62:2127-29
    • (2004) Neurology , vol.62 , pp. 2127-2129
    • Devos, D.1    Moreau, C.2    Lassalle, P.3
  • 26
    • 0029068713 scopus 로고
    • Quantitative study of synaptophysin immunoreactivity of cerebral cortex and spinal cord in motor neuron disease
    • Ince PG, Slade J, Chinnery RM, et al. Quantitative study of synaptophysin immunoreactivity of cerebral cortex and spinal cord in motor neuron disease. J Neuropathol Exp Neurol 1995;54:673-79
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 673-679
    • Ince, P.G.1    Slade, J.2    Chinnery, R.M.3
  • 27
  • 28
    • 0031577277 scopus 로고    scopus 로고
    • Differential involvement of synaptic vesicle and presynaptic plasma membrane proteins in Alzheimer's disease
    • Shimohama S, Kamiya S, Taniguchi T, et al. Differential involvement of synaptic vesicle and presynaptic plasma membrane proteins in Alzheimer's disease. Biochem Biophys Res Commun 1997;236:239-42
    • (1997) Biochem Biophys Res Commun , vol.236 , pp. 239-242
    • Shimohama, S.1    Kamiya, S.2    Taniguchi, T.3
  • 29
    • 0036934956 scopus 로고    scopus 로고
    • Differential expression between synaptic vesicle proteins and presynaptic plasma membrane proteins in the anterior horn of amyotrophic lateral sclerosis
    • Berl
    • Ikemoto A, Nakamura S, Akiguchi I, et al. Differential expression between synaptic vesicle proteins and presynaptic plasma membrane proteins in the anterior horn of amyotrophic lateral sclerosis. Acta Neuropathol (Berl) 2002;103:179-87
    • (2002) Acta Neuropathol , vol.103 , pp. 179-187
    • Ikemoto, A.1    Nakamura, S.2    Akiguchi, I.3
  • 30
    • 0032547036 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression in transient focal cerebral ischemia in the rat
    • Cobbs CS, Chen J, Greenberg DA, et al. Vascular endothelial growth factor expression in transient focal cerebral ischemia in the rat. Neurosci Lett 1998;249:79-82
    • (1998) Neurosci Lett , vol.249 , pp. 79-82
    • Cobbs, C.S.1    Chen, J.2    Greenberg, D.A.3
  • 31
    • 0032921140 scopus 로고    scopus 로고
    • Vascular endothelial growth/permeability factor in spinal cord injury
    • Vaquero J, Zurita M, de Oya S, et al. Vascular endothelial growth/permeability factor in spinal cord injury. J Neurosurg 1999;90:220-23
    • (1999) J Neurosurg , vol.90 , pp. 220-223
    • Vaquero, J.1    Zurita, M.2    De Oya, S.3
  • 32
    • 0032903416 scopus 로고    scopus 로고
    • Vascular, glial and neuronal effects of vascular endothelial growth factor in mesencephalic expiant cultures
    • Silverman WF, Krum JM, Mani N, et al. Vascular, glial and neuronal effects of vascular endothelial growth factor in mesencephalic expiant cultures. Neuroscience 1999;90:1529-41
    • (1999) Neuroscience , vol.90 , pp. 1529-1541
    • Silverman, W.F.1    Krum, J.M.2    Mani, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.