-
1
-
-
0028197325
-
Primary brain tumors: Review of etiology, diagnosis, and treatment
-
Newton HB. Primary brain tumors: review of etiology, diagnosis, and treatment. Am. Fam. Phys. 49, 787-797 (1994).
-
(1994)
Am. Fam. Phys.
, vol.49
, pp. 787-797
-
-
Newton, H.B.1
-
2
-
-
0035559064
-
Current epidemiological trends and surveillance issues in brain tumors
-
Davis FG, McCarthy BJ. Current epidemiological trends and surveillance issues in brain tumors. Expert Rev. AntiCancer Ther. 1, 395-401 (2001).
-
(2001)
Expert Rev. AntiCancer Ther.
, vol.1
, pp. 395-401
-
-
Davis, F.G.1
McCarthy, B.J.2
-
3
-
-
0036787611
-
Epidemiology of primary brain tumors: Current concepts and review of the literature
-
Wrensch M, Minn Y, Chew T, Bondy M, Berger MS. Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro-Oncol. 4, 278-299 (2002).
-
(2002)
Neuro-Oncol.
, vol.4
, pp. 278-299
-
-
Wrensch, M.1
Minn, Y.2
Chew, T.3
Bondy, M.4
Berger, M.S.5
-
5
-
-
0033557811
-
Neurological complications of systemic cancer
-
Newton HB. Neurological complications of systemic cancer. Am. Fam. Phys. 59, 878-886 (1999).
-
(1999)
Am. Fam. Phys.
, vol.59
, pp. 878-886
-
-
Newton, H.B.1
-
6
-
-
0033581097
-
Cancer surveillance series: Brain and other central nervous system cancers: recent trends in incidence and mortality
-
Legler JM, Ries LA, Smith MA et al. Cancer surveillance series: brain and other central nervous system cancers: recent trends in incidence and mortality. J. Natl Cancer Inst. 91, 1382-1390 (1999).
-
(1999)
J. Natl Cancer Inst.
, vol.91
, pp. 1382-1390
-
-
Legler, J.M.1
Ries, L.A.2
Smith, M.A.3
-
8
-
-
0027516695
-
Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults
-
Fine HA, Dear KBG, Loeffler JS, Black PM, Canellos GP. Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults. Cancer 71, 2585-2597 (1993).
-
(1993)
Cancer
, vol.71
, pp. 2585-2597
-
-
Fine, H.A.1
Dear, K.B.G.2
Loeffler, J.S.3
Black, P.M.4
Canellos, G.P.5
-
9
-
-
0037161024
-
Chemotherapy in adult high-grade glioma: A systematic review and meta-analysis of individual patient data from 12 randomized trials
-
Stewart LA, Burdett S, Parmar MKB et al. Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomized trials. Lancet 359, 1011-1018 (2002).
-
(2002)
Lancet
, vol.359
, pp. 1011-1018
-
-
Stewart, L.A.1
Burdett, S.2
Parmar, M.K.B.3
-
10
-
-
0242382624
-
Molecular neuro-oncology and the development of "targeted" therapeutic strategies for brain tumors. Part 1: Growth factor and ras signaling pathways
-
Newton HB. Molecular neuro-oncology and the development of "targeted" therapeutic strategies for brain tumors. Part 1: growth factor and ras signaling pathways. Expert Rev. AntiCancer Ther. 3, 595-614 (2003). Thorough review.
-
(2003)
Expert Rev. AntiCancer Ther.
, vol.3
, pp. 595-614
-
-
Newton, H.B.1
-
11
-
-
1142287357
-
Molecular neuro-oncology and the development of "targeted" therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH, and angiogenesis
-
Newton HB. Molecular neuro-oncology and the development of "targeted" therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH, and angiogenesis. Expert Rev. AntiCancer Ther. 4, 105-128 (2004). Thorough review.
-
(2004)
Expert Rev. AntiCancer Ther.
, vol.4
, pp. 105-128
-
-
Newton, H.B.1
-
12
-
-
17544366279
-
Molecular neuro-oncology and the development of "targeted" therapeutic strategies for brain tumors. Part 5: Apoptosis and cell cycle
-
Newton HB. Molecular neuro-oncology and the development of "targeted" therapeutic strategies for brain tumors. Part 5: apoptosis and cell cycle. Expert Rev. AntiCancer Ther. 5, 355-378 (2005). Thorough review.
-
(2005)
Expert Rev. AntiCancer Ther.
, vol.5
, pp. 355-378
-
-
Newton, H.B.1
-
13
-
-
31544481156
-
Targeted molecular therapy of malignant gliomas
-
Kesari S, Ramakrishna N, Sauvageot C, Stiles CD, Wen PY. Targeted molecular therapy of malignant gliomas. Curr. Oncol. Rep. 8, 58-70 (2006). Thorough review.
-
(2006)
Curr. Oncol. Rep.
, vol.8
, pp. 58-70
-
-
Kesari, S.1
Ramakrishna, N.2
Sauvageot, C.3
Stiles, C.D.4
Wen, P.Y.5
-
14
-
-
32944479646
-
Therapeutic advances in the treatment of glioblastoma: Rationale and potential role of targeted agents
-
Reardon DA, Wen PY. Therapeutic advances in the treatment of glioblastoma: rationale and potential role of targeted agents. Oncologist 11, 152-164 (2006).
-
(2006)
Oncologist
, vol.11
, pp. 152-164
-
-
Reardon, D.A.1
Wen, P.Y.2
-
15
-
-
32344446371
-
Development of the blood-brain barrier: A historical point of view
-
Ribatti D, Nico B, Crivellato E, Artico M. Development of the blood-brain barrier: a historical point of view. Anat. Rec. B New Anat. 289, 3-8 (2006).
-
(2006)
Anat. Rec. B New Anat.
, vol.289
, pp. 3-8
-
-
Ribatti, D.1
Nico, B.2
Crivellato, E.3
Artico, M.4
-
16
-
-
0033391691
-
Blood-brain barrier biology and methodology
-
Pardridge WM. Blood-brain barrier biology and methodology. J. Neurovirol. 5, 556-569 (1999).
-
(1999)
J. Neurovirol.
, vol.5
, pp. 556-569
-
-
Pardridge, W.M.1
-
17
-
-
26244456551
-
Molecular biology of the blood-brain barrier
-
Pardridge WM. Molecular biology of the blood-brain barrier. Mol. Biotechnol. 30, 57-70 (2005). Excellent review of blood-brain barrier (BBB) biology.
-
(2005)
Mol. Biotechnol.
, vol.30
, pp. 57-70
-
-
Pardridge, W.M.1
-
18
-
-
12344336803
-
Blood-brain barrier genomics, proteomics, and new transporter discovery
-
Shusta EV. Blood-brain barrier genomics, proteomics, and new transporter discovery. NeuroRx 2, 151-161 (2005).
-
(2005)
NeuroRx
, vol.2
, pp. 151-161
-
-
Shusta, E.V.1
-
19
-
-
0033526179
-
Carrier-mediated or specialized transport of drugs across the blood-brain barrier
-
Tsuji A, Tamai II. Carrier-mediated or specialized transport of drugs across the blood-brain barrier. Adv. Drug Deliv. Rev. 36, 277-290 (1999).
-
(1999)
Adv. Drug Deliv. Rev.
, vol.36
, pp. 277-290
-
-
Tsuji, A.1
Tamai, I.I.2
-
20
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
Abbott NJ, Ronnback L, Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci. 7, 41-53 (2006). Detailed review of astrocyte-endothelial interactions
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 41-53
-
-
Abbott, N.J.1
Ronnback, L.2
Hansson, E.3
-
21
-
-
0035576934
-
Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier
-
Huber JD, Egleton RD, Davis TP. Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier. Trends Neurosci. 24, 719-725 (2001).
-
(2001)
Trends Neurosci.
, vol.24
, pp. 719-725
-
-
Huber, J.D.1
Egleton, R.D.2
Davis, T.P.3
-
22
-
-
0036627211
-
Tight junctions of the blood-brain barrier: Development, composition, and regulation
-
Wolburg H, Lippoldt A. Tight junctions of the blood-brain barrier: development, composition, and regulation. Vascul. Pharmacol. 38, 223-337 (2002).
-
(2002)
Vascul. Pharmacol.
, vol.38
, pp. 223-337
-
-
Wolburg, H.1
Lippoldt, A.2
-
23
-
-
16844366165
-
Occludin: Structure, function, and regulation
-
Feldman GJ, Mullin JM, Ryan MP. Occludin: structure, function, and regulation. Adv. Drug Deliv. Rev. 57, 883-917 (2005).
-
(2005)
Adv. Drug Deliv. Rev.
, vol.57
, pp. 883-917
-
-
Feldman, G.J.1
Mullin, J.M.2
Ryan, M.P.3
-
24
-
-
33645963995
-
Claudins and epithelial paracellular transport
-
Van Itallie CM, Anderson JM. Claudins and epithelial paracellular transport. Ann. Rev. Physiol. 68, 403-429 (2006).
-
(2006)
Ann. Rev. Physiol.
, vol.68
, pp. 403-429
-
-
Van Itallie, C.M.1
Anderson, J.M.2
-
25
-
-
0141644213
-
The JAM family of junctional adhesion molecules
-
Bazzoni G. The JAM family of junctional adhesion molecules. Curr. Opin. Cell Biol. 15, 525-530 (2003).
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 525-530
-
-
Bazzoni, G.1
-
26
-
-
0029095287
-
Zonula occludens (ZO)-1 and ZO-2: Membrane-associated guanylate kinase homologues (MAGuKs) of the tight junction
-
Anderson JM, Fanning AS, Lapierre L, Van Itallie CM. Zonula occludens (ZO)-1 and ZO-2: membrane-associated guanylate kinase homologues (MAGuKs) of the tight junction. Biochem. Soc. Trans. 23, 470-475 (1995).
-
(1995)
Biochem. Soc. Trans.
, vol.23
, pp. 470-475
-
-
Anderson, J.M.1
Fanning, A.S.2
Lapierre, L.3
Van Itallie, C.M.4
-
28
-
-
0034674901
-
A family of drug transporters: The multidrug resistance-associated proteins
-
Borst P, Evers R, Kool M, Wijnholds J. A family of drug transporters: the multidrug resistance-associated proteins. J. Natl Cancer Inst. 92, 1295-1302 (2000).
-
(2000)
J. Natl Cancer Inst.
, vol.92
, pp. 1295-1302
-
-
Borst, P.1
Evers, R.2
Kool, M.3
Wijnholds, J.4
-
29
-
-
0032754657
-
Microvesesel organization and structure in experimental brain tumors: Microvessel populations with distinctive structural and functional properties
-
Schlageter KE, Molnar P, Lapin GD, Groothuis DR. Microvesesel organization and structure in experimental brain tumors: microvessel populations with distinctive structural and functional properties. Microvasc. Res. 58, 312-328 (1999).
-
(1999)
Microvasc. Res.
, vol.58
, pp. 312-328
-
-
Schlageter, K.E.1
Molnar, P.2
Lapin, G.D.3
Groothuis, D.R.4
-
30
-
-
0033755180
-
The blood-brain and blood-tumor barriers: A review of strategies for increasing drug delivery
-
Groothuis DR. The blood-brain and blood-tumor barriers: a review of strategies for increasing drug delivery. Neuro-oncol. 2, 45-59 (2000).
-
(2000)
Neuro-oncol.
, vol.2
, pp. 45-59
-
-
Groothuis, D.R.1
-
31
-
-
33750633200
-
Chemotherapy principles
-
Berger MS, Prados MD (Eds). Elsevier Saunders, PA, USA
-
Parney IF, Prados MD. Chemotherapy principles. In: Textbook of Neuro-oncol.ogy. Berger MS, Prados MD (Eds). Elsevier Saunders, PA, USA 11, 75-79 (2005).
-
(2005)
Textbook of Neuro-oncology
, vol.11
, pp. 75-79
-
-
Parney, I.F.1
Prados, M.D.2
-
32
-
-
0031959341
-
CNS drug design based on principles of blood-brain barrier transport
-
Pardridge WM. CNS drug design based on principles of blood-brain barrier transport. J. Neurochem. 70, 1781-1792 (1998).
-
(1998)
J. Neurochem.
, vol.70
, pp. 1781-1792
-
-
Pardridge, W.M.1
-
34
-
-
0019124032
-
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability
-
Levin VA. Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability. J. Med. Chem. 23, 682-684 (1980).
-
(1980)
J. Med. Chem.
, vol.23
, pp. 682-684
-
-
Levin, V.A.1
-
35
-
-
0022622673
-
Chemotherapy of brain tumors: Physiological and pharmacokinetic considerations
-
Blasberg RG, Groothuis DR. Chemotherapy of brain tumors: physiological and pharmacokinetic considerations. Semin. Oncol. 13, 70-82 (1986).
-
(1986)
Semin. Oncol.
, vol.13
, pp. 70-82
-
-
Blasberg, R.G.1
Groothuis, D.R.2
-
36
-
-
0014682986
-
Molecular forces governing non-electrolyte permeation through cell membranes
-
Diamond JM, Wright EM. Molecular forces governing non-electrolyte permeation through cell membranes. Proc. R. Soc. Lond., B, Biol. Sci. 171, 273-316 (1969).
-
(1969)
Proc. R. Soc. Lond., B, Biol. Sci.
, vol.171
, pp. 273-316
-
-
Diamond, J.M.1
Wright, E.M.2
-
37
-
-
0023219734
-
Transport of molecules in the interstitium: A review
-
Jain RK. Transport of molecules in the interstitium: a review. Cancer Res. 47, 3039-3051 (1987).
-
(1987)
Cancer Res.
, vol.47
, pp. 3039-3051
-
-
Jain, R.K.1
-
38
-
-
0033870271
-
Oncotic pressure in solid tumors is elevated
-
Stohrer M, Boucher Y, Stangassinger M, Jain RK. Oncotic pressure in solid tumors is elevated. Cancer Res. 60, 4251-4255 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 4251-4255
-
-
Stohrer, M.1
Boucher, Y.2
Stangassinger, M.3
Jain, R.K.4
-
39
-
-
0030099527
-
Transporting therapeutics across the blood-brain barrier
-
Abbott NJ, Romero IA. Transporting therapeutics across the blood-brain barrier. Mol. Med. Today 2(3), 106-113 (1996).
-
(1996)
Mol. Med. Today
, vol.2
, Issue.3
, pp. 106-113
-
-
Abbott, N.J.1
Romero, I.A.2
-
40
-
-
0031965788
-
Outwitting the blood-brain barrier for therapeutic purposes: Osmotic opening and other means
-
Kroll RA, Neuwelt EA. Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means. Neurosurg. 42, 1083-1100 (1998).
-
(1998)
Neurosurg.
, vol.42
, pp. 1083-1100
-
-
Kroll, R.A.1
Neuwelt, E.A.2
-
41
-
-
0034756894
-
Brain drug targeting and gene technologies
-
Pardridge WM. Brain drug targeting and gene technologies. Jpn. J. Pharmacol. 87, 97-103 (2001).
-
(2001)
Jpn. J. Pharmacol.
, vol.87
, pp. 97-103
-
-
Pardridge, W.M.1
-
42
-
-
0036463371
-
Drug and gene targeting to the brain with molecular Trojan horses
-
Pardridge WM. Drug and gene targeting to the brain with molecular Trojan horses. Nature Rev. Drug Discov. 1, 131-139 (2002). Detailed overview of vector-mediated delivery approaches.
-
(2002)
Nature Rev. Drug Discov.
, vol.1
, pp. 131-139
-
-
Pardridge, W.M.1
-
43
-
-
0036144376
-
Targeting neurotherapeutic agents through the blood-brain barrier
-
Pardridge WM. Targeting neurotherapeutic agents through the blood-brain barrier. Arch. Neurol. 59, 35-40 (2002).
-
(2002)
Arch. Neurol.
, vol.59
, pp. 35-40
-
-
Pardridge, W.M.1
-
44
-
-
16644367919
-
Brain endothelial cells as pharmacological targets in brain tumors
-
Demeule M, Régina A, Annabi B, Bertrand Y, Bojanowski MW, Béleveau R. Brain endothelial cells as pharmacological targets in brain tumors. Mol. Neurobiol. 30, 157-183 (2004).
-
(2004)
Mol. Neurobiol.
, vol.30
, pp. 157-183
-
-
Demeule, M.1
Régina, A.2
Annabi, B.3
Bertrand, Y.4
Bojanowski, M.W.5
Béleveau, R.6
-
45
-
-
17344363713
-
Cell biology of the neurovascular unit: Implications for drug delivery across the blood-brain barrier
-
McCarty JH. Cell biology of the neurovascular unit: implications for drug delivery across the blood-brain barrier. Assay Drugs Dev. Technol. 3, 89-95 (2005).
-
(2005)
Assay Drugs Dev. Technol.
, vol.3
, pp. 89-95
-
-
McCarty, J.H.1
-
46
-
-
12344319635
-
Development of neuropeptide drugs that cross the blood-brain barrier
-
Egleton RD, Davis TP. Development of neuropeptide drugs that cross the blood-brain barrier. NeuroRx 2, 44-53 (2005).
-
(2005)
NeuroRx
, vol.2
, pp. 44-53
-
-
Egleton, R.D.1
Davis, T.P.2
-
47
-
-
12344273724
-
Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems
-
Tsuji A. Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems. NeuroRx 2, 54-62 (2005). Excellent review of carriermediated transport.
-
(2005)
NeuroRx
, vol.2
, pp. 54-62
-
-
Tsuji, A.1
-
48
-
-
12244300933
-
Drug delivery and in vitro models of the blood-brain barrier
-
Cucullo L, Aumayr B, Rapp E, Janigro D. Drug delivery and in vitro models of the blood-brain barrier. Curr. Opin. Drug Discov. Devel. 8, 89-99 (2005).
-
(2005)
Curr. Opin. Drug Discov. Devel.
, vol.8
, pp. 89-99
-
-
Cucullo, L.1
Aumayr, B.2
Rapp, E.3
Janigro, D.4
-
49
-
-
0028270064
-
Hydrogen bonding potential as a determinant of the in vitro and in situ blood-brain permeability of peptides
-
Chikhale EG, Ng KY, Burton PS, Borchardt RT. Hydrogen bonding potential as a determinant of the in vitro and in situ blood-brain permeability of peptides. Pharm. Res. 11, 412-419 (1994).
-
(1994)
Pharm. Res.
, vol.11
, pp. 412-419
-
-
Chikhale, E.G.1
Ng, K.Y.2
Burton, P.S.3
Borchardt, R.T.4
-
50
-
-
0028273935
-
Glycation increases the permeability of proteins across the blood-nerve and blood-brain barriers
-
Poduslo JF, Curran GL. Glycation increases the permeability of proteins across the blood-nerve and blood-brain barriers. Brain Res. Mol. Brain Res. 23, 157-162 (1994).
-
(1994)
Brain Res. Mol. Brain Res.
, vol.23
, pp. 157-162
-
-
Poduslo, J.F.1
Curran, G.L.2
-
51
-
-
0034693398
-
Improved bioavailability to the brain of glycosylated Met-enkephalin analogs
-
Egleton RD, Mitchell SA, Huber JD et al. Improved bioavailability to the brain of glycosylated Met-enkephalin analogs. Brain Res. 881, 37-46 (2000).
-
(2000)
Brain Res.
, vol.881
, pp. 37-46
-
-
Egleton, R.D.1
Mitchell, S.A.2
Huber, J.D.3
-
52
-
-
0344420226
-
Pharmacokinetic and biodistribution properties of poly(ethyleneglycol)- protein conjugates
-
Caliceti P, Veronese FM. Pharmacokinetic and biodistribution properties of poly(ethyleneglycol)-protein conjugates. Adv. Drug Deliv. Rev. 26, 1261-1277 (2003).
-
(2003)
Adv. Drug Deliv. Rev.
, vol.26
, pp. 1261-1277
-
-
Caliceti, P.1
Veronese, F.M.2
-
54
-
-
4644301510
-
Conjugates of peptides and proteins to polyethylene glycols
-
Morpurgo M, Veronese FM. Conjugates of peptides and proteins to polyethylene glycols. Methods Mol. Biol. 283, 45-70 (2004).
-
(2004)
Methods Mol. Biol.
, vol.283
, pp. 45-70
-
-
Morpurgo, M.1
Veronese, F.M.2
-
55
-
-
0031901771
-
Combined use of carboxyl-directed protein pegylation and vector-mediated blood-brain barrier drug delivery system optimizes brain uptake of brain-derived neurotropic factor following intravenous administration
-
Pardridge WM, Wu D, Sakane T. Combined use of carboxyl-directed protein pegylation and vector-mediated blood-brain barrier drug delivery system optimizes brain uptake of brain-derived neurotropic factor following intravenous administration. Pharm. Res. 15, 576-582 (1998).
-
(1998)
Pharm. Res.
, vol.15
, pp. 576-582
-
-
Pardridge, W.M.1
Wu, D.2
Sakane, T.3
-
56
-
-
0043261498
-
Pegylation: Engineering improved biopharmaceuticals for oncology
-
Molineux G. Pegylation: engineering improved biopharmaceuticals for oncology. Pharmacother. 23, S3-S8 (2003).
-
(2003)
Pharmacother.
, vol.23
-
-
Molineux, G.1
-
57
-
-
0032894155
-
Retention of biologic activity of human epidermal growth factor following conjugation to a blood-brain barrier drug delivery vector via an extended poly(ethylene glycol) linker
-
Deguche Y, Kurihara A, Pardridge WM. Retention of biologic activity of human epidermal growth factor following conjugation to a blood-brain barrier drug delivery vector via an extended poly(ethylene glycol) linker. Bioconjugate Chem. 10, 32-37 (1999).
-
(1999)
Bioconjugate Chem.
, vol.10
, pp. 32-37
-
-
Deguche, Y.1
Kurihara, A.2
Pardridge, W.M.3
-
58
-
-
0038399929
-
Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: Laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport
-
Borlongan CV, Emerich DF. Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport. Brain Res. Bull. 60, 297-306 (2003).
-
(2003)
Brain Res. Bull.
, vol.60
, pp. 297-306
-
-
Borlongan, C.V.1
Emerich, D.F.2
-
59
-
-
0037388250
-
A randomized, double-blind, placebo-controlled, Phase 2 study of RMP-7 in combination with carboplatin administered intravenously for the treatment of recurrent malignant glioma
-
Prados MD, Schold SC, Fine HA et al. A randomized, double-blind, placebo-controlled, Phase 2 study of RMP-7 in combination with carboplatin administered intravenously for the treatment of recurrent malignant glioma. Neuro-oncol. 5, 96-103 (2003).
-
(2003)
Neuro-oncol.
, vol.5
, pp. 96-103
-
-
Prados, M.D.1
Schold, S.C.2
Fine, H.A.3
-
60
-
-
0035937595
-
Nanoparticulate systems for brain delivery of drugs
-
Kreuter J. Nanoparticulate systems for brain delivery of drugs. Adv. Drug Deliv. Rev. 47, 65-81 (2001).
-
(2001)
Adv. Drug Deliv. Rev.
, vol.47
, pp. 65-81
-
-
Kreuter, J.1
-
61
-
-
0036205158
-
Nanoparticle technology for drug delivery across the blood-brain barier
-
Lockman PR, Mumper RJ, Khan MA, Allen DD. Nanoparticle technology for drug delivery across the blood-brain barier. Drug Dev. Ind. Pharm. 28, 1-13 (2002).
-
(2002)
Drug Dev. Ind. Pharm.
, vol.28
, pp. 1-13
-
-
Lockman, P.R.1
Mumper, R.J.2
Khan, M.A.3
Allen, D.D.4
-
62
-
-
12344307628
-
Drug transport to brain with targeted nanoparticles
-
Olivier JC. Drug transport to brain with targeted nanoparticles. NeuroRx 2, 108-119 (2005).
-
(2005)
NeuroRx
, vol.2
, pp. 108-119
-
-
Olivier, J.C.1
-
63
-
-
29244472857
-
Neuroscience nanotechnology: Progress, opportunities, and challenges
-
Silva GA. Neuroscience nanotechnology: progress, opportunities, and challenges. Nature Rev. Neurosci. 7, 65-74 (2006).
-
(2006)
Nature Rev. Neurosci.
, vol.7
, pp. 65-74
-
-
Silva, G.A.1
-
64
-
-
33646673555
-
A review of nanocarrier-based CNS delivery systems
-
Tiwari SB, Amiji MM. A review of nanocarrier-based CNS delivery systems. Curr. Drug Deliv. 3, 219-232 (2006). Detailed review of nanocarrier-based CNS delivery.
-
(2006)
Curr. Drug Deliv.
, vol.3
, pp. 219-232
-
-
Tiwari, S.B.1
Amiji, M.M.2
-
65
-
-
0029360414
-
The controlled intravenous delivery of drugs using PEG-coated sterically stabilized nanospheres
-
Gref R, Domb A, Quellec P et al. The controlled intravenous delivery of drugs using PEG-coated sterically stabilized nanospheres. Adv. Drug Deliv. Rev. 16, 215-233 (1995).
-
(1995)
Adv. Drug Deliv. Rev.
, vol.16
, pp. 215-233
-
-
Gref, R.1
Domb, A.2
Quellec, P.3
-
66
-
-
24144461213
-
Nanotechnology-based drug delivery for cancer
-
Jain KK. Nanotechnology-based drug delivery for cancer. Technol. Cancer Res. Treat. 4, 407-416 (2005).
-
(2005)
Technol. Cancer Res. Treat.
, vol.4
, pp. 407-416
-
-
Jain, K.K.1
-
67
-
-
0036690684
-
Synthesis of pegylated immunonanoparticles
-
Olivier JC, Huertas R, Lee HJ, Calon F, Pardridge WM. Synthesis of pegylated immunonanoparticles. Pharm. Res. 19, 1137-1143 (2002).
-
(2002)
Pharm. Res.
, vol.19
, pp. 1137-1143
-
-
Olivier, J.C.1
Huertas, R.2
Lee, H.J.3
Calon, F.4
Pardridge, W.M.5
-
68
-
-
0037168963
-
Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma
-
Gelperina SE, Khalansky AS, Skidan IN et al. Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma. Toxicol. Lett. 126, 131-141 (2002).
-
(2002)
Toxicol. Lett.
, vol.126
, pp. 131-141
-
-
Gelperina, S.E.1
Khalansky, A.S.2
Skidan, I.N.3
-
69
-
-
12144288634
-
Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles
-
Steininger SC, Kreuter J, Khalanskyi AS et al. Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles. Int. J. Cancer 109, 759-767 (2004).
-
(2004)
Int. J. Cancer
, vol.109
, pp. 759-767
-
-
Steininger, S.C.1
Kreuter, J.2
Khalanskyi, A.S.3
-
70
-
-
4544240398
-
Paclitaxel nanoparticles for the potential treatment of brain tumors
-
Koziara JM, Lockman PR, Allen DD, Mumper RJ. Paclitaxel nanoparticles for the potential treatment of brain tumors. J. Control Release 99, 259-269 (2004).
-
(2004)
J. Control Release
, vol.99
, pp. 259-269
-
-
Koziara, J.M.1
Lockman, P.R.2
Allen, D.D.3
Mumper, R.J.4
-
71
-
-
7444256573
-
Negative preclinical results with stealth nanospheres-encapsulated doxorubicin in an orthotopic murine brain tumor model
-
Brigger I, Morizet J, Laudani L et al. Negative preclinical results with stealth nanospheres-encapsulated doxorubicin in an orthotopic murine brain tumor model. J. Control Release 100, 29-40 (2004).
-
(2004)
J. Control Release
, vol.100
, pp. 29-40
-
-
Brigger, I.1
Morizet, J.2
Laudani, L.3
-
72
-
-
11244266036
-
Liposomal anticancer therapy: Pharmacokinetic and clinical aspects
-
Di Paolo A. Liposomal anticancer therapy: pharmacokinetic and clinical aspects. J. Chemother. 16, 90-93 (2004).
-
(2004)
J. Chemother.
, vol.16
, pp. 90-93
-
-
Di Paolo, A.1
-
73
-
-
13844294438
-
Entrapment of small molecules and nucleic acid-based drugs in liposomes
-
Fenske DB, Cullis PR. Entrapment of small molecules and nucleic acid-based drugs in liposomes. Methods Enzymol. 391, 7-40 (2005). Thorough review of liposomal technology.
-
(2005)
Methods Enzymol.
, vol.391
, pp. 7-40
-
-
Fenske, D.B.1
Cullis, P.R.2
-
74
-
-
12344262085
-
Drug transport to brain with targeted liposomes
-
Schnyder A, Huwyler J. Drug transport to brain with targeted liposomes. NeuroRx 2, 99-107 (2005).
-
(2005)
NeuroRx
, vol.2
, pp. 99-107
-
-
Schnyder, A.1
Huwyler, J.2
-
75
-
-
33645540053
-
Liposomal drug delivery system from laboratory to clinic
-
Kshirsagar NA, Pandya SK, Kirodian BG, Sanath S. Liposomal drug delivery system from laboratory to clinic. J. Postgrad. Med. 51(Suppl. 1), S5-S15 (2005).
-
(2005)
J. Postgrad. Med.
, vol.51
, Issue.SUPPL. 1
-
-
Kshirsagar, N.A.1
Pandya, S.K.2
Kirodian, B.G.3
Sanath, S.4
-
76
-
-
24644455541
-
The formulation of lipid-based nanotechnologies for the delivery of fixed dose anticancer drug combinations
-
Ramsay EC, Dos Santos N, Dragowska WH, Laskin JJ, Bally MB. The formulation of lipid-based nanotechnologies for the delivery of fixed dose anticancer drug combinations. Curr. Drug Deliv. 2, 341-351 (2005).
-
(2005)
Curr. Drug Deliv.
, vol.2
, pp. 341-351
-
-
Ramsay, E.C.1
Dos Santos, N.2
Dragowska, W.H.3
Laskin, J.J.4
Bally, M.B.5
-
77
-
-
0028222291
-
Long-circulating (sterically stabilized) liposomes for targeted drug delivery
-
Allen TM. Long-circulating (sterically stabilized) liposomes for targeted drug delivery. Trends Pharmacol. Sci. 15, 215-220 (1994).
-
(1994)
Trends Pharmacol. Sci.
, vol.15
, pp. 215-220
-
-
Allen, T.M.1
-
78
-
-
0030447660
-
Brain drug delivery of small molecules using immunoliposomes
-
Huwyler J, Wu D, Pardridge WM. Brain drug delivery of small molecules using immunoliposomes. Proc. Natl Acad. Sci. USA 93, 14164-14169 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 14164-14169
-
-
Huwyler, J.1
Wu, D.2
Pardridge, W.M.3
-
79
-
-
0036665418
-
Antisense gene therapy of brain cancer with an artificial virus gene delivery system
-
Zhang Y, Zhu C, Pardridge WM. Antisense gene therapy of brain cancer with an artificial virus gene delivery system. Mol. Ther. 6, 67-72 (2002).
-
(2002)
Mol. Ther.
, vol.6
, pp. 67-72
-
-
Zhang, Y.1
Zhu, C.2
Pardridge, W.M.3
-
80
-
-
13844298737
-
The liposomal formulation of doxorubicin
-
Abraham SA, Waterhouse DN, Mayer LD, Cullis PR, Madden TD, Bally MB. The liposomal formulation of doxorubicin. Meth. Enzymol. 391, 71-97 (2005).
-
(2005)
Meth. Enzymol.
, vol.391
, pp. 71-97
-
-
Abraham, S.A.1
Waterhouse, D.N.2
Mayer, L.D.3
Cullis, P.R.4
Madden, T.D.5
Bally, M.B.6
-
81
-
-
11144310022
-
Advantages of liposomal delivery systems for anthracyclines
-
Allen TM, Martin FJ. Advantages of liposomal delivery systems for anthracyclines. Sem. in Oncol. 31, 5-15 (2004).
-
(2004)
Sem. in Oncol.
, vol.31
, pp. 5-15
-
-
Allen, T.M.1
Martin, F.J.2
-
82
-
-
11144289529
-
Pegylated liposomal doxorubicin: Proof of principle using preclinical animal models and pharmacokinetic studies
-
Vail DM, Amantea MA, Colbern GT, Martin FJ, Hilger RA, Working PK. Pegylated liposomal doxorubicin: proof of principle using preclinical animal models and pharmacokinetic studies. Sem. in Oncol. 31, 16-35 (2004).
-
(2004)
Sem. in Oncol.
, vol.31
, pp. 16-35
-
-
Vail, D.M.1
Amantea, M.A.2
Colbern, G.T.3
Martin, F.J.4
Hilger, R.A.5
Working, P.K.6
-
83
-
-
0029585915
-
Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: Biodistribution and therapeutic efficacy
-
Siegal T, Horowitz A, Gabizon A. Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: biodistribution and therapeutic efficacy. J. Neurosurg. 83, 1029-1037 (1995).
-
(1995)
J. Neurosurg.
, vol.83
, pp. 1029-1037
-
-
Siegal, T.1
Horowitz, A.2
Gabizon, A.3
-
84
-
-
0030770632
-
Liposome-mediated therapy of intracranial brain tumors in a rat model
-
Sharma US, Sharma A, Chau RI, Straubinger RM. Liposome-mediated therapy of intracranial brain tumors in a rat model. Pharm. Res. 14, 992-998 (1997).
-
(1997)
Pharm. Res.
, vol.14
, pp. 992-998
-
-
Sharma, U.S.1
Sharma, A.2
Chau, R.I.3
Straubinger, R.M.4
-
85
-
-
11144355073
-
Distribution of liposomes into brain and rat brain tumor models by convection-enhanced delivery monitored with magnetic resonance imaging
-
Saito R, Bringas JR, McKnight TR et al. Distribution of liposomes into brain and rat brain tumor models by convection-enhanced delivery monitored with magnetic resonance imaging. Cancer Res. 64, 2572-2579 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 2572-2579
-
-
Saito, R.1
Bringas, J.R.2
McKnight, T.R.3
-
86
-
-
0033734065
-
High intratumoral accumulation of stealth liposomal doxorubicin (Caelyx) in glioblastomas and in metastatic brain tumors
-
Koukourakis MI, Koukouraki S, Fezoulidis I et al. High intratumoral accumulation of stealth liposomal doxorubicin (Caelyx) in glioblastomas and in metastatic brain tumors. Br. J. Cancer 83, 1281-1286 (2000).
-
(2000)
Br. J. Cancer
, vol.83
, pp. 1281-1286
-
-
Koukourakis, M.I.1
Koukouraki, S.2
Fezoulidis, I.3
-
87
-
-
0035477616
-
Long-term stabilization in patients with malignant glioma after treatment with liposomal doxorubicin
-
Fabel K, Dietrich J, Hau P et al. Long-term stabilization in patients with malignant glioma after treatment with liposomal doxorubicin. Cancer 92, 1936-1942 (2001).
-
(2001)
Cancer
, vol.92
, pp. 1936-1942
-
-
Fabel, K.1
Dietrich, J.2
Hau, P.3
-
88
-
-
12144291225
-
Pegylated liposomal doxorubicin-efficacy in patients with recurrent high-grade glioma
-
Hau P, Fabel K, Baumgart U et al. Pegylated liposomal doxorubicin-efficacy in patients with recurrent high-grade glioma. Cancer 100, 1199-1207 (2004).
-
(2004)
Cancer
, vol.100
, pp. 1199-1207
-
-
Hau, P.1
Fabel, K.2
Baumgart, U.3
-
89
-
-
0942277091
-
Phase 2 study of temozolomide and Caelyx in patients with recurrent glioblastoma multiforme
-
Chua SL, Rosenthal RA, Wong SS et al. Phase 2 study of temozolomide and Caelyx in patients with recurrent glioblastoma multiforme. Neuro-oncol. 6, 38-43 (2004).
-
(2004)
Neuro-oncol.
, vol.6
, pp. 38-43
-
-
Chua, S.L.1
Rosenthal, R.A.2
Wong, S.S.3
-
90
-
-
13844275414
-
Liposome-mediated suicide gene therapy in humans
-
Reszka RC, Jacobs A, Voges J. Liposome-mediated suicide gene therapy in humans. Methods Enzymol. 391, 200-208 (2005).
-
(2005)
Methods Enzymol.
, vol.391
, pp. 200-208
-
-
Reszka, R.C.1
Jacobs, A.2
Voges, J.3
-
91
-
-
23444437213
-
Convection-enhanced delivery of macromolecules in the brain
-
Bobo RH, Laske DW, Akbasak A, Morrison PF, Dedrick RL, Oldfield EH. Convection-enhanced delivery of macromolecules in the brain. Proc. Natl Acad. Sci. USA 91, 2076-2080 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 2076-2080
-
-
Bobo, R.H.1
Laske, D.W.2
Akbasak, A.3
Morrison, P.F.4
Dedrick, R.L.5
Oldfield, E.H.6
-
92
-
-
0029001712
-
Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion
-
Lieberman DM, Laske DW, Morrison PF, Bandiewicz KS, Oldfield EH. Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion. J. Neurosurg. 82, 1021-1029 (1995).
-
(1995)
J. Neurosurg.
, vol.82
, pp. 1021-1029
-
-
Lieberman, D.M.1
Laske, D.W.2
Morrison, P.F.3
Bandiewicz, K.S.4
Oldfield, E.H.5
-
93
-
-
4344601659
-
Extensive distribution of liposomes in rodent brains and brain tumors following convection-enhanced delivery
-
Mamot C, Nguyen JB, Pourdehnad M et al. Extensive distribution of liposomes in rodent brains and brain tumors following convection-enhanced delivery. J. Neuro-oncol. 68, 1-9 (2004).
-
(2004)
J. Neuro-oncol.
, vol.68
, pp. 1-9
-
-
Mamot, C.1
Nguyen, J.B.2
Pourdehnad, M.3
-
95
-
-
33646828478
-
Convection-enhanced delivery of targeted toxins for malignant glioma
-
Hall WA, Scherr GT. Convection-enhanced delivery of targeted toxins for malignant glioma. Expert Opin. Drug Deliv. 3, 371-377 (2006).
-
(2006)
Expert Opin. Drug Deliv.
, vol.3
, pp. 371-377
-
-
Hall, W.A.1
Scherr, G.T.2
-
96
-
-
33747174300
-
Convection-enhanced delivery of immunotoxins and radioisotopes for treatment of malignant gliomas
-
Vandergrift WA, Patel SJ, Nicholas JS, Varma AK. Convection-enhanced delivery of immunotoxins and radioisotopes for treatment of malignant gliomas. Neurosurg. Focus 20, E13 (2006).
-
(2006)
Neurosurg. Focus
, vol.20
-
-
Vandergrift, W.A.1
Patel, S.J.2
Nicholas, J.S.3
Varma, A.K.4
-
97
-
-
33750615565
-
Intratumoral administration and convection-enhanced delivery
-
Newton HB (Ed.). Elsevier Medical Publishers - Academic Press, London, UK
-
Chen MY, Chen ZJ, Gillies GT, Haar PJ, Broaddus WC. Intratumoral administration and convection-enhanced delivery. In: Handbook of Brain Tumor Chemotherapy. Newton HB (Ed.). Elsevier Medical Publishers - Academic Press, London, UK, 19, 295-304 (2006).
-
(2006)
Handbook of Brain Tumor Chemotherapy
, vol.19
, pp. 295-304
-
-
Chen, M.Y.1
Chen, Z.J.2
Gillies, G.T.3
Haar, P.J.4
Broaddus, W.C.5
-
98
-
-
0002951467
-
Polymer-based drug delivery to the brain
-
Brem H, Langer R. Polymer-based drug delivery to the brain. Science Med. 3, 2-11 (1996).
-
(1996)
Science Med.
, vol.3
, pp. 2-11
-
-
Brem, H.1
Langer, R.2
-
99
-
-
17844380277
-
Local delivery of antineoplastic agents by controlled-release polymers for the treatment of malignant brain tumours
-
Raza SM, Pradilla G, Legnani FG et al. Local delivery of antineoplastic agents by controlled-release polymers for the treatment of malignant brain tumours. Expert Opin. Biol. Ther. 5, 477-494 (2005). Detailed review of the topic.
-
(2005)
Expert Opin. Biol. Ther.
, vol.5
, pp. 477-494
-
-
Raza, S.M.1
Pradilla, G.2
Legnani, F.G.3
-
100
-
-
33750607310
-
Interstitial chemotherapy and polymer-drug delivery
-
Newton HB (Ed.). Elsevier Medical Publishers - Academic Press, London, UK
-
Haque RM, Amundson E, Dorsi M, Brem H. Interstitial chemotherapy and polymer-drug delivery. In: Handbook of Brain Tumor Chemotherapy. Newton HB (Ed.). Elsevier Medical Publishers - Academic Press, London, UK, 20, 274-294 (2006). Thorough overview of polymer-drug delivery.
-
(2006)
Handbook of Brain Tumor Chemotherapy
, vol.20
, pp. 274-294
-
-
Haque, R.M.1
Amundson, E.2
Dorsi, M.3
Brem, H.4
-
101
-
-
0028917333
-
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery of biodegradable polymers of chemotherapy for recurrent gliomas
-
The Polymer-Brain Tumor Treatment Group
-
Brem H, Piantadosi S, Burger PC et al. Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery of biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-Brain Tumor Treatment Group. Lancet 345, 1008-1012 (1995).
-
(1995)
Lancet
, vol.345
, pp. 1008-1012
-
-
Brem, H.1
Piantadosi, S.2
Burger, P.C.3
-
102
-
-
0030929137
-
Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: A randomized double-blind study
-
Valtonen S, Timonen U, Toivanen P et al. Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: a randomized double-blind study. Neurosurg. 41, 44-48 (1997).
-
(1997)
Neurosurg.
, vol.41
, pp. 44-48
-
-
Valtonen, S.1
Timonen, U.2
Toivanen, P.3
-
103
-
-
0037384037
-
A Phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma
-
Westphal M, Hilt DC, Bortey E et al. A Phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma. Neuro-oncol. 5, 79-88 (2003).
-
(2003)
Neuro-oncol.
, vol.5
, pp. 79-88
-
-
Westphal, M.1
Hilt, D.C.2
Bortey, E.3
-
105
-
-
0030845872
-
Recent progress in radioimmunotherapy of cancer
-
Meredith RF, LoBuglio AF. Recent progress in radioimmunotherapy of cancer. Oncology 11, 979-987 (1997).
-
(1997)
Oncology
, vol.11
, pp. 979-987
-
-
Meredith, R.F.1
LoBuglio, A.F.2
-
106
-
-
0024463062
-
Antibody guided diagnosis and therapy of brain gliomas using radiolabeled monoclonal antibodies against epidermal growth factor receptor and placental alkaline phosphatase
-
Kalofonos HP, Pawlikowska TR, Hemingway A et al. Antibody guided diagnosis and therapy of brain gliomas using radiolabeled monoclonal antibodies against epidermal growth factor receptor and placental alkaline phosphatase. J. Nucl. Med. 30, 1636-1645 (1989).
-
(1989)
J. Nucl. Med.
, vol.30
, pp. 1636-1645
-
-
Kalofonos, H.P.1
Pawlikowska, T.R.2
Hemingway, A.3
-
107
-
-
0031456943
-
Local application of radiolabeled monoclonal antibodies in the treatment of high grade malignant gliomas. A six-year clinical experience
-
Riva P, Franceschi G, Arista A et al. Local application of radiolabeled monoclonal antibodies in the treatment of high grade malignant gliomas. A six-year clinical experience. Cancer 80, 2733-2742 (1997).
-
(1997)
Cancer
, vol.80
, pp. 2733-2742
-
-
Riva, P.1
Franceschi, G.2
Arista, A.3
-
108
-
-
0031801502
-
Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: Phase I trial results
-
Bigner DD, Brown MT, Friedman AH et al. Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: Phase I trial results. J. Clin. Oncol. 16, 2202-2212 (1998).
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 2202-2212
-
-
Bigner, D.D.1
Brown, M.T.2
Friedman, A.H.3
-
109
-
-
0034669697
-
Phase trial results of iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with newly diagnosed malignant gliomas
-
Cokgor I, Akabani G, Kuan CT et al. Phase trial results of iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with newly diagnosed malignant gliomas. J. Clin. Oncol. 18, 3862-3872 (2000).
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 3862-3872
-
-
Cokgor, I.1
Akabani, G.2
Kuan, C.T.3
-
110
-
-
0036498790
-
131I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas
-
131I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. J. Clin. Oncol. 20, 1389-1397 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 1389-1397
-
-
Reardon, D.A.1
Akabani, G.2
Colemen, R.E.3
-
111
-
-
33646564104
-
(131)I-chTNT-1/B mAb: Tumour necrosis therapy for malignant astrocytic glioma
-
Shapiro WR, Carpenter SP, Roberts K, Shan JS. (131)I-chTNT-1/B mAb: tumour necrosis therapy for malignant astrocytic glioma. Expert Opin. Biol. Ther. 6, 539-545 (2006).
-
(2006)
Expert Opin. Biol. Ther.
, vol.6
, pp. 539-545
-
-
Shapiro, W.R.1
Carpenter, S.P.2
Roberts, K.3
Shan, J.S.4
-
112
-
-
0026598909
-
Immunotoxins and central nervous system neoplasia
-
Hall WA, Fodstad O. Immunotoxins and central nervous system neoplasia. J. Neurosurg. 76, 1-12 (1992).
-
(1992)
J. Neurosurg.
, vol.76
, pp. 1-12
-
-
Hall, W.A.1
Fodstad, O.2
-
113
-
-
0036053691
-
Local treatment of brain tumors with targeted chimera cytotoxic proteins
-
Debinski W. Local treatment of brain tumors with targeted chimera cytotoxic proteins. Cancer Investig. 20, 801-809 (2002).
-
(2002)
Cancer Investig.
, vol.20
, pp. 801-809
-
-
Debinski, W.1
-
114
-
-
0037295311
-
DAB389EGF fusion protein therapy of refractory glioblastoma multiforme
-
Cohen KA, Liu T, Bissonette R, Puri RK, Frankel AE. DAB389EGF fusion protein therapy of refractory glioblastoma multiforme. Curr. Pharm. Biotechnol. 4, 39-49 (2003).
-
(2003)
Curr. Pharm. Biotechnol.
, vol.4
, pp. 39-49
-
-
Cohen, K.A.1
Liu, T.2
Bissonette, R.3
Puri, R.K.4
Frankel, A.E.5
-
116
-
-
0031451777
-
Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors
-
Laske DW, Youle RJ, Oldfield EH. Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors. Nature Med. 3, 1362-1368 (1997).
-
(1997)
Nature Med.
, vol.3
, pp. 1362-1368
-
-
Laske, D.W.1
Youle, R.J.2
Oldfield, E.H.3
-
117
-
-
0344876636
-
Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas
-
Weaver M, Laske DW. Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas. J. Neuro-oncol. 65, 3-13 (2003).
-
(2003)
J. Neuro-oncol.
, vol.65
, pp. 3-13
-
-
Weaver, M.1
Laske, D.W.2
-
118
-
-
10744219583
-
Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-α and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors
-
Sampson JH, Akabani G, Archer GE et al. Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-α and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors. J. Neuro-Oncol. 65, 27-35 (2003).
-
(2003)
J. Neuro-Oncol.
, vol.65
, pp. 27-35
-
-
Sampson, J.H.1
Akabani, G.2
Archer, G.E.3
-
119
-
-
0041562430
-
Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma
-
Weber F, Asher A, Bucholz R et al. Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma. J. Neuro-oncol. 64, 125-137 (2003).
-
(2003)
J. Neuro-oncol.
, vol.64
, pp. 125-137
-
-
Weber, F.1
Asher, A.2
Bucholz, R.3
-
120
-
-
9944264848
-
Intratumoral convection-enhanced delivery of IL13-PE38QQR cytotoxin for recurrent malignant glioma without planned resection: A Phase I/II study
-
Weingart J, Tatter S, Rosenfeld S et al. Intratumoral convection-enhanced delivery of IL13-PE38QQR cytotoxin for recurrent malignant glioma without planned resection: a Phase I/II study. Neuro-oncol. 5, 357 (2003).
-
(2003)
Neuro-oncol.
, vol.5
, pp. 357
-
-
Weingart, J.1
Tatter, S.2
Rosenfeld, S.3
-
121
-
-
28844462115
-
Final results of Phase I/II studies of IL13-PE38QQR administered intratumorally (IT) and/or peritumorally (PT) via convection-enhanced delivery (CED) in patients undergoing tumor resection for recurrent malignant glioma
-
Prados M, Kunwar S, Lang FF et al. Final results of Phase I/II studies of IL13-PE38QQR administered intratumorally (IT) and/or peritumorally (PT) via convection-enhanced delivery (CED) in patients undergoing tumor resection for recurrent malignant glioma. Proc. Am. Soc. Clin. Oncol. 23, S115 (2005).
-
(2005)
Proc. Am. Soc. Clin. Oncol.
, vol.23
-
-
Prados, M.1
Kunwar, S.2
Lang, F.F.3
-
123
-
-
0031570025
-
Functional and pharmacokinetic properties of antibody/avidin fusion proteins
-
Shin SU, Wu D, Ramanathan R, Pardridge WM, Morrison SL. Functional and pharmacokinetic properties of antibody/avidin fusion proteins. J. Immunol. 158, 4797-4804 (1997).
-
(1997)
J. Immunol.
, vol.158
, pp. 4797-4804
-
-
Shin, S.U.1
Wu, D.2
Ramanathan, R.3
Pardridge, W.M.4
Morrison, S.L.5
-
124
-
-
0025828176
-
Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier
-
Friden PM, Walus LR, Musso GF, Taylor MA, Malfroy B, Starzyk RM. Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier. Proc. Natl Acad. Sci. USA 88, 4771-4775 (1991).
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 4771-4775
-
-
Friden, P.M.1
Walus, L.R.2
Musso, G.F.3
Taylor, M.A.4
Malfroy, B.5
Starzyk, R.M.6
-
125
-
-
0025836586
-
Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier in vivo
-
Pardridge WM, Buciak JL, Friden PM. Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier in vivo. J. Pharmacol. Exp. Ther. 259, 66-70 (1991).
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.259
, pp. 66-70
-
-
Pardridge, W.M.1
Buciak, J.L.2
Friden, P.M.3
-
126
-
-
0033996507
-
Transport across the primate blood-brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor
-
Coloma MJ, Lee HJ, Kurihara A et al. Transport across the primate blood-brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor. Pharm. Res. 17, 266-274 (2000).
-
(2000)
Pharm. Res.
, vol.17
, pp. 266-274
-
-
Coloma, M.J.1
Lee, H.J.2
Kurihara, A.3
-
127
-
-
0042899083
-
Blood-brain barrier drug targeting: The future of brain drug development
-
Pardridge WM. Blood-brain barrier drug targeting: the future of brain drug development. Mol. Interven. 3, 90-105 (2003).
-
(2003)
Mol. Interven.
, vol.3
, pp. 90-105
-
-
Pardridge, W.M.1
|