Intratumoral Administration and Convection-Enhanced Delivery

Handbook of Brain Tumor Chemotherapy

Volumn , Issue , 2006, Pages 295-304

  Chen, Mike Yue ^a   Chen, Zhi jian ^a   Gillies, George T ^a   Haar, Peter J ^a   Broaddus, William C ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33750615565     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012088410-0/50058-5     Document Type: Chapter

References (52)

1. C. Nicholson and J.M. Phillips (1981) Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum. J Physiol 321 225-257.
2. C. Nicholson (1985) Diffusion from an injected volume of a substance in brain tissue with arbitrary volume fraction and tortuosity. Brain Res 333(2), 325-329.
3. C. Nicholson (1993) Ion-selective microelectrodes and diffusion measurements as tools to explore the brain cell microenvironment. J Neurosci Methods 48(3), 199-213.
4. P.J. Basser (1992) Interstitial pressure, volume, and flow during infusion into brain tissue. Microvasc Res 44(2), 143-165.
5. P.F. Morrison, D.W. Laske, H. Bobo and R.L. Dedrick (1994) High-flow microinfusion: tissue penetration and pharmacodynamics. Am J Physiol 266(1), R292-R305.
6. S. Kalyanasundaram, V.D. Calhoun and K.W. Leong (1997) A finite element model for predicting the distribution of drugs delivered intracranially to the brain. Am J Physiol 273(5), R1810-R1821.
7. T. Nagashima, N. Tamaki, S. Matsumoto, B. Horwitz and Y. Seguchi (1987) Biomechanics of hydrocephalus: a new theoretical model. Neurosurgery 21(6), 898-904.
8. Z.J. Chen, W.C. Broaddus, R.R. Viswanathan, R. Raghavan and G. Gillies (2002) Intraparenchymal drug delivery via positive-pressure infusion: experimental and modeling studies of poroelasticity in brain phantom gels. IEEE Trans Biomed Eng 49(2), 85-96.
9. Z.J. Chen, G.T. Gillies, W.C. Broaddus, et al. (2004) A realistic brain tissue phantom for intraparenchymal infusion studies. J Neurosurg 101(2), 314-322.
10. R. Raghavan, T. Poston and R.R. Viswanathan (2005) A method and apparatus for targeting material delivery to tissue. U.S. Patent No.6,549,803, April 15, 2003
11. R.G. Thorne and W.H. Frey (2001) Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations. Clin Pharmacokinet 40(12), 907-946.
12. R.R. Kumari, J.S. Dhaliwal, M.A. Stoodley and N.R. Jones (1999) Perivascular CSF flow in the rat cerebellum. J Clin Neurosci 6(2), 143-146.
13. W.C. Broaddus, G.T. Gillies and J. Kucharczyk (2005) Image-guided intraparenchymal drug and cell therapy. R.E. Latchaw, J. Kucharczyk, M.E. Moseley (Eds) Imaging of the Nervous System: Diagnostic and Therapeutic Applications Vol. 2 New York: W. B. Saunders 1467-1476.
14. R.H. Bobo, D.W. Laske, A. Akbasak, P.F. Morrison, R.L. Dedrick and E.H. Oldfield (1994) Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci USA 91 2076-2080. 6
15. W.C. Broaddus, S.S. Prabhu, G.T. Gillies, et al. (1998) Distribution and stability of antisense phosphorothioate oligonucleotides in rodent brain following direct intraparenchymal controlled-rate infusion. J Neurosurg 88(4), 734-742.
16. J.N. Bruce, A. Falavigna, J.P. Johnson, et al. (2000) Intracerebral clysis in a rat glioma model. Neurosurgery 46(3), 683-691.
17. M.Y. Chen, R.R. Lonser, P.F. Morrison, L.S. Governale and E.H. Oldfield (1999) Variables affecting Convection-enhanced delivery to the striatum: a systematic examination of rate of infusion, cannula size, infusate concentration, and tissue-cannula sealing time. J Neurosurg 90(2), 315-320.
18. J. Cunningham, Y. Oiwa, D. Nagy, G. Podsakoff, P. Colosi and K.S. Bankiewicz (2000) Distribution of AAV-TK following intracranial Convection-enhanced delivery into rats. Cell Transplant 9(5), 585-594.
19. D.R. Groothuis, S. Ward, A.C. Itskovich, et al. (1999) Comparison of 14C-sucrose delivery to the brain by intravenous, intraventricular, and convection-enhanced intracerebral infusion. J Neurosurg 90(2), 321-331.
20. D.R. Groothuis, H. Benalcazar, C.V. Allen, et al. (2000) Comparison of cytosine arabinoside delivery to rat brain by intravenous, intrathecal, intraventricular and intraparenchymal routes of administration. Brain Res 856(1–2), 281-290.
21. P.J. Haar, J.E. Stewart, G.T. Gillies, S.S. Prabhu and W.C. Broaddus (2001) Quantitative three-dimensional analysis and diffusion modeling of oligonucleotide concentrations after direct intraparenchymal brain infusion. IEEE Transactions on Biomedical Engineering 48(5), 560-569.
22. M.G. Kaiser, A.T. Parsa, R.L. Fine, J.S. Hall, I. Chakrabarti and J. Bruce (2000) Tissue distribution and antitumor activity of topotecan delivered by intracerebral clysis in a rat glioma model. Neurosurgery 47(6), 1391-1398.
23. R.A. Kroll, M.A. Pagel, L.L. Muldoon, S. Roman-Goldstein and E.A. Neuwelt (1996) Increasing volume of distribution to the brain with interstitial infusion: dose, rather than convection, might be the most important factor. Neurosurgery 38(4), 746-752.
24. D.M. Lieberman, D.W. Laske, P.F. Morrison, K.S. Bankiewicz and E.H. Oldfield (1995) Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion. J Neurosurg 82(6), 1021-1029.
25. J.B. Nguyen, R. Sanchez-Pernaute, J. Cunningham and K.S. Bankiewicz (2001) Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain. Neuroreport 12(9), 1961-1964.
26. S.S. Prabhu, W.C. Broaddus, G.T. Gillies, W.G. Loudon, Z.J. Chen and B. Smith (1998) Distribution of macromolecular dyes in brain using positive pressure infusion: a model for direct controlled delivery of therapeutic agents. Surg Neurol 50(4), 367-375.
27. G.C. Zirzow, O.A. Sanchez, G.J. Murray, R.O. Brady and E.H. Oldfield (1999) Delivery, distribution, and neuronal uptake of exogenous mannose-terminal glucocerebrosidase in the intact rat brain. Neurochem Res 24(2), 301-305.
28. K.S. Bankiewicz, J.L. Eberling, M. Kohutnicka, et al. (2000) Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach. Exp Neurol 164(1), 2-14.
29. D.W. Laske, P.F. Morrison, D.M. Lieberman, et al. (1997) Chronic interstitial infusion of protein to primate brain: determination of drug distribution and clearance with single-photon emission computerized tomography imaging. J Neurosurg 87(4), 586-594.
30. D.M. Lieberman, M.E. Corthesy, A. Cummins and E.H. Oldfield (1999) Reversal of experimental parkinsonism by using selective chemical ablation of the medial globus pallidus. J Neurosurg 90(5), 928-934.
31. R.R. Lonser, M.E. Corthesy, P.F. Morrison, N. Gogate and E.H. Oldfield (1999) Convection-enhanced selective excitotoxic ablation of the neurons of the globus pallidus internus for treatment of parkinsonism in nonhuman primates. J Neurosurg 91(2), 294-302.
32. R.R. Lonser, S. Walbridge, K. Garmestani, et al. (2002) Successful and safe perfusion of the primate brainstem: in vivo magnetic resonance imaging of macromolecular distribution during infusion. J Neurosurg 97(4), 905-913.
33. Chen, M. Y., Hoffer, A., Morrison, P. F. et al. Surface Properties, more than size, limit convective distribution of viral-sized particles and viruses in the CNS. J Neurosurg in press.
34. W. Yang, R.F. Barth, D.M. Adams, et al. (2002) Convection-enhanced delivery of boronated epidermal growth factor for molecular targeting of EGF receptor-positive gliomas. Cancer Res 62(22), 6552-6558.
35. R. Saito, J.R. Bringas, A. Panner, et al. (2004) Convection-enhanced delivery of tumor necrosis factor-related apoptosis-inducing ligand with systemic administration of temozolomide prolongs survival in an intracranial glioblastoma xenograft model. Cancer Res 64(19), 6858-6862.
36. D. Brust, J. Feden, J. Farnsworth, C. Amir, W.C. Broaddus and K. Valerie (2000) Radiosensitization of rat glioma with bromodeoxycytidine and adenovirus expressing herpes simplex virus-thymidine kinase delivered by slow, rate-controlled positive pressure infusion. Cancer Gene Ther 7(5), 778-788.
37. C. Mamot, J.B. Nguyen, M. Pourdehnad, et al. (2004) Extensive distribution of liposomes in rodent brains and brain tumors following Convection-enhanced delivery. J Neurooncol 68(1), 1-9.
38. M. Vavra, M.J. Ali, E.W. Kang, et al. (2004) Comparative pharmacokinetics of 14C-sucrose in RG-2 rat gliomas after intravenous and Convection-enhanced delivery. Neuro-oncol 6(2), 104-112.
39. D.W. Laske, R.J. Youle and E.H. Oldfield (1997) Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors. Nat Med 3(12), 1362-1368.
40. W.A. Hall, E. Rustamzadeh and A.L. Asher (2003) CED in clinical trials. Neurosurg Focus 14(2), 1-4.
41. S. Kunwar (2003) Convection enhanced delivery of IL13-PE38QQR for treatment of recurrent malignant glioma: presentation of interim findings from ongoing phase 1 studies. Acta Neurochir Suppl 88 105-111.
42. S.R. Husain and R.K. Puri (2003) Interleukin-13 receptor-directed cytotoxin for malignant glioma therapy: from bench to bedside. J Neurooncol 65(1), 37-48.
43. F.W. Weber, F. Floeth, A. Asher, et al. (2003) Local convection enhanced delivery of IL4-Pseudomonas exotoxin (NBI-3001) for treatment of patients with recurrent malignant glioma. Acta Neurochir Suppl 88 93-103.
44. D. Pietronigro, F. Drnovsky, H. Cravioto and J. Ransohoff (2003) DTI-015 produces cures in T9 gliosarcoma. Neoplasia 5(1), 17-22.
45. S.J. Hassenbusch, E.M. Nardone, V.A. Levin, N. Leeds and D. Pietronigro (2003) Stereotactic injection of DTI-015 into recurrent malignant gliomas: phase I/II trial. Neoplasia 5(1), 9-16.
46. Z. Lidar, Y. Mardor, T. Jonas, et al. (2004) Convection-enhanced delivery of paclitaxel for the treatment of recurrent malignant glioma: a phase I/II clinical study. J Neurosurg 100(3), 472-479.
47. A. Merlo, O. Hausmann, M. Wasner, et al. (1999) Locoregional regulatory peptide receptor targeting with the diffusible somatostatin analogue 90Y-labeled DOTA0-D-Phe1-Tyr3-octreotide (DOTATOC): a pilot study in human gliomas. Clin Cancer Res 5(5), 1025-1033.
48. V. Papanastassiou, B.L. Pizer, H.B. Coakham, J. Bullimore, T. Zananiri and J.T. Kemshead (1993) Treatment of recurrent and cystic malignant gliomas by a single intracavity injection of 131I monoclonal antibody: feasibility, pharmacokinetics and dosimetry. Br J Cancer 67(1), 144-151.
49. P. Riva, A. Arista, G. Franceschi, et al. (1995) Local treatment of malignant gliomas by direct infusion of specific monoclonal antibodies labeled with 131I: comparison of the results obtained in recurrent and newly diagnosed tumors. Cancer Res 55(23), 5952s-5956s. Suppl
50. P. Hadaczek, H. Mirek, M.S. Berger and K. Bankiewicz (2005) Limited efficacy of gene transfer in herpes simplex virus-thymidine kinase/ganciclovir gene therapy for brain tumors. J Neurosurg 102(2), 328-335.
51. J. Voges, R. Reszka, A. Gossmann, et al. (2003) Imaging-guided Convection-enhanced delivery and gene therapy of glioblastoma. Ann Neurol 54(4), 479-487.
52. J. Kucharczyk, W.C. Broaddus, H.L. Fillmore and G.T. Gillies (2005) Cell Delivery Catheter and Method. U.S. Patent No.6,599,274, July 29, 2003