메뉴 건너뛰기




Volumn 7, Issue 1, 2006, Pages 65-74

Neuroscience nanotechnology: Progress, opportunities and challenges

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN; FREE RADICAL; MACROGOL; MRZ 2 576; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NANOPARTICLE; NEUROPEPTIDE; OLIGONUCLEOTIDE; POLY(BUTYLCYANOACRYLATE); POLYETHYLENEIMINE; POLYMER; POLYSORBATE 80; QUANTUM DOT; UNCLASSIFIED DRUG;

EID: 29244472857     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn1827     Document Type: Review
Times cited : (336)

References (100)
  • 1
    • 1642474289 scopus 로고    scopus 로고
    • DNA nanotubes self-assembled from triple-crossover tiles as templates for conductive nanowires
    • Liu, D., Park, S. H., Reif, J. H. & LaBean, T. H. DNA nanotubes self-assembled from triple-crossover tiles as templates for conductive nanowires. Proc. Natl Acad. Sci. USA 101, 717-722 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 717-722
    • Liu, D.1    Park, S.H.2    Reif, J.H.3    LaBean, T.H.4
  • 2
    • 0035902938 scopus 로고    scopus 로고
    • Nanowire nanosensors for highly sensitive and selective detection of biological and chemical species
    • Cui, Y., Wei, Q., Park, H. & Lieber, C. M. Nanowire nanosensors for highly sensitive and selective detection of biological and chemical species. Science 293, 1289-1292 (2001).
    • (2001) Science , vol.293 , pp. 1289-1292
    • Cui, Y.1    Wei, Q.2    Park, H.3    Lieber, C.M.4
  • 3
    • 15944402003 scopus 로고    scopus 로고
    • Nanotechnology approaches for the regeneration and neuroprotection of the central nervous system
    • Silva, G. A. Nanotechnology approaches for the regeneration and neuroprotection of the central nervous system. Surg. Neurol. 63, 301-306 (2005).
    • (2005) Surg. Neurol. , vol.63 , pp. 301-306
    • Silva, G.A.1
  • 4
    • 29244459088 scopus 로고    scopus 로고
    • Small neuroscience: The nanostructure of the central nervous system and emerging nanotechnology applications
    • Silva, G. A. Small neuroscience: the nanostructure of the central nervous system and emerging nanotechnology applications. Curr. Nanosci. 3, 225-236 (2005).
    • (2005) Curr. Nanosci. , vol.3 , pp. 225-236
    • Silva, G.A.1
  • 5
    • 0041387466 scopus 로고    scopus 로고
    • Biocompatibility of layer-by-layer self-assembled nanofilm on silicone rubber for neurons
    • Ai, H. et al. Biocompatibility of layer-by-layer self-assembled nanofilm on silicone rubber for neurons. J. Neurosci. Methods 128, 1-8 (2003).
    • (2003) J. Neurosci. Methods , vol.128 , pp. 1-8
    • Ai, H.1
  • 6
    • 0037109261 scopus 로고    scopus 로고
    • Culture of neural cells on silicon wafers with nano-scale surface topograph
    • Fan, Y. W. et al. Culture of neural cells on silicon wafers with nano-scale surface topograph. J. Neurosci. Methods 120, 17-23 (2002).
    • (2002) J. Neurosci. Methods , vol.120 , pp. 17-23
    • Fan, Y.W.1
  • 7
    • 9644274000 scopus 로고    scopus 로고
    • Conducting polymers grown in hydrogel scaffolds coated on neural prosthetic devices
    • Kim, D. H., Abidian, M. & Martin, D. C. Conducting polymers grown in hydrogel scaffolds coated on neural prosthetic devices. J. Biomed. Mater. Res. A 71, 577-585 (2004).
    • (2004) J. Biomed. Mater. Res. A , vol.71 , pp. 577-585
    • Kim, D.H.1    Abidian, M.2    Martin, D.C.3
  • 8
    • 5044235542 scopus 로고    scopus 로고
    • Micropatterning of nanoengineered surfaces to study neuronal cell attachment in vitro
    • Mohammed, J. S., DeCoster, M. A. & McShane, M. J. Micropatterning of nanoengineered surfaces to study neuronal cell attachment in vitro. Biomacromolecules 5, 1745-1755 (2004).
    • (2004) Biomacromolecules , vol.5 , pp. 1745-1755
    • Mohammed, J.S.1    DeCoster, M.A.2    McShane, M.J.3
  • 9
    • 2342460928 scopus 로고    scopus 로고
    • Preparation of protein gradients through the controlled deposition of protein-nanoparticle conjugates onto functionalized surfaces
    • Kramer, S. et al. Preparation of protein gradients through the controlled deposition of protein-nanoparticle conjugates onto functionalized surfaces. J. Am. Chem. Soc. 126, 5388-5395 (2004).
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 5388-5395
    • Kramer, S.1
  • 10
    • 2442719087 scopus 로고    scopus 로고
    • Nanostructured surface modification of ceramic-based microelectrodes to enhance biocompatibility for a direct brain-machine interface
    • Moxon, K. A. et al. Nanostructured surface modification of ceramic-based microelectrodes to enhance biocompatibility for a direct brain-machine interface. IEEE Trans. Biomed. Eng. 51, 881-889 (2004). A good example of electrode modification using nanoengineered materials to improve neuronal adhesion while limiting the effects of contaminating cells to improve the functionality of the electrodes.
    • (2004) IEEE Trans. Biomed. Eng. , vol.51 , pp. 881-889
    • Moxon, K.A.1
  • 11
    • 2942674806 scopus 로고    scopus 로고
    • A novel MEA/AFM platform for measurement of real-time, nanometric morphological alterations of electrically stimulated neuroblastoma cells
    • Shenai, M. B. et al. A novel MEA/AFM platform for measurement of real-time, nanometric morphological alterations of electrically stimulated neuroblastoma cells. IEEE Trans. Nanobioscience 3, 111-117 (2004).
    • (2004) IEEE Trans. Nanobioscience , vol.3 , pp. 111-117
    • Shenai, M.B.1
  • 12
    • 9644302948 scopus 로고    scopus 로고
    • Activation of membrane receptors by a neurotransmitter conjugate designed for surface attachment
    • Vu, T. Q. et al. Activation of membrane receptors by a neurotransmitter conjugate designed for surface attachment. Biomaterials 26, 1895-1903 (2005). An excellent example of a nanoengineered cell-signalling platform technology designed to selectively and controllably stimulate target neurons by immobilizing neurotransmitter molecules on a surface.
    • (2005) Biomaterials , vol.26 , pp. 1895-1903
    • Vu, T.Q.1
  • 13
    • 0141447818 scopus 로고    scopus 로고
    • Assembly and characterization of biofunctional neurotransmitter- immobilized surfaces for interaction with postsynaptic membrane receptors
    • Saifuddin, U. et al. Assembly and characterization of biofunctional neurotransmitter-immobilized surfaces for interaction with postsynaptic membrane receptors. J. Biomed. Mater. Res. A 66, 184-191 (2003).
    • (2003) J. Biomed. Mater. Res. A , vol.66 , pp. 184-191
    • Saifuddin, U.1
  • 15
    • 0142116238 scopus 로고    scopus 로고
    • Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking
    • Dahan, M. et al. Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking. Science 302, 442-445 (2003). First major work showing the application of functionalized quantum dots to target neurons in the investigation of a specific neurophysiological process. The authors took advantage of the physical properties of quantum dots to achieve single-particle tracking of glycine receptors.
    • (2003) Science , vol.302 , pp. 442-445
    • Dahan, M.1
  • 16
    • 19644391139 scopus 로고    scopus 로고
    • Targeting quantum dots to surface proteins in living cells with biotin ligase
    • Howarth, M., Takao, K., Hayashi, Y. & Ting, A. Y. Targeting quantum dots to surface proteins in living cells with biotin ligase. Proc. Natl Acad. Sci. USA 102, 7583-7588 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 7583-7588
    • Howarth, M.1    Takao, K.2    Hayashi, Y.3    Ting, A.Y.4
  • 17
    • 18144414655 scopus 로고    scopus 로고
    • Surfactant-assisted synthesis of water-soluble and biocompatible semiconductor quantum dot micelles
    • Fan, H. et al. Surfactant-assisted synthesis of water-soluble and biocompatible semiconductor quantum dot micelles. Nano. Lett. 5, 645-648 (2005).
    • (2005) Nano. Lett. , vol.5 , pp. 645-648
    • Fan, H.1
  • 18
    • 18144391953 scopus 로고    scopus 로고
    • Peptide-conjugated quantum dots activate neuronal receptors and initiate downstream signaling of neurite growth
    • Vu, T. Q. et al. Peptide-conjugated quantum dots activate neuronal receptors and initiate downstream signaling of neurite growth. Nano. Lett. 5, 603-607 (2005).
    • (2005) Nano. Lett. , vol.5 , pp. 603-607
    • Vu, T.Q.1
  • 19
    • 33644533247 scopus 로고    scopus 로고
    • Quantum dot applications in neuroscience: New tools for probing neurons and glia
    • in the press
    • Pathak, S., Cao, E., Davidson, M., Jin, S.-H. & Silva, G. A. Quantum dot applications in neuroscience: new tools for probing neurons and glia. J. Neurosci. (in the press).
    • J. Neurosci.
    • Pathak, S.1    Cao, E.2    Davidson, M.3    Jin, S.-H.4    Silva, G.A.5
  • 20
    • 0346500607 scopus 로고    scopus 로고
    • Fabrication of nano-structured porous PLLA scaffold intended for nerve tissue engineering
    • Yang, F. et al. Fabrication of nano-structured porous PLLA scaffold intended for nerve tissue engineering. Biomaterials 25, 1891-1900 (2004).
    • (2004) Biomaterials , vol.25 , pp. 1891-1900
    • Yang, F.1
  • 21
    • 1442281238 scopus 로고    scopus 로고
    • Selective differentiation of neural progenitor cells by high-epitope density nanofibers
    • Silva, G. A. et al. Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science 303, 1352-1355 (2004). First major work describing the application of a nanoengineered material designed specifically for neural regeneration that had multiple, functional properties, including in vitro self-assembly under physiological conditions and preferential differentiation of neurons over astrocytes.
    • (2004) Science , vol.303 , pp. 1352-1355
    • Silva, G.A.1
  • 22
    • 0035028276 scopus 로고    scopus 로고
    • Fullerene-based antioxidants and neurodegenerative disorders
    • Dugan, L. L. et al. Fullerene-based antioxidants and neurodegenerative disorders. Parkinsonism Relat. Disord. 7, 243-246 (2001).
    • (2001) Parkinsonism Relat. Disord. , vol.7 , pp. 243-246
    • Dugan, L.L.1
  • 23
    • 0030130429 scopus 로고    scopus 로고
    • Buckminsterfullerenol free radical scavengers reduce excitotoxic and apoptotic death of cultured cortical neurons
    • Dugan, L. L., Gabrielsen, J. K., Yu, S. P., Lin, T. S. & Choi, D. W. Buckminsterfullerenol free radical scavengers reduce excitotoxic and apoptotic death of cultured cortical neurons. Neurobiol. Dis. 3, 129-135 (1996).
    • (1996) Neurobiol. Dis. , vol.3 , pp. 129-135
    • Dugan, L.L.1    Gabrielsen, J.K.2    Yu, S.P.3    Lin, T.S.4    Choi, D.W.5
  • 24
    • 0001897915 scopus 로고    scopus 로고
    • Carboxyfullerenesas neuroprotective agents
    • Dugan, L. L. et al. Carboxyfullerenesas neuroprotective agents. Proc. Natl Acad. Sci. USA 94, 9434-9439 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9434-9439
    • Dugan, L.L.1
  • 25
    • 0034668386 scopus 로고    scopus 로고
    • 60, fullerenols, as glutamate receptor antagonists and neuroprotective agents
    • 60, fullerenols, as glutamate receptor antagonists and neuroprotective agents. J. Neurosci. Res. 62, 600-607 (2000).
    • (2000) J. Neurosci. Res. , vol.62 , pp. 600-607
    • Jin, H.1
  • 26
    • 0035028276 scopus 로고    scopus 로고
    • Dugan, L. L. et al. Fullerene-based antioxidants and neurodegenerative disorders. 7, 243-246 (2001). A good example of the application of fullerene-derived nanoparticles intended to protect the CNS from free radical toxicity following injury. This and related research have shown promising initial results in vivo.
    • (2001) Fullerene-based Antioxidants and Neurodegenerative Disorders , vol.7 , pp. 243-246
    • Dugan, L.L.1
  • 27
    • 0036205158 scopus 로고    scopus 로고
    • Nanoparticle technology for drug delivery across the blood-brain barrier
    • Lockman, P. R., Mumper, R. J., Khan, M. A. & Allen, D. D. Nanoparticle technology for drug delivery across the blood-brain barrier. Drug Dev. Ind. Pharm. 28, 1-13 (2002). Reviews current strategies for delivering drugs and other small molecules across the BBB.
    • (2002) Drug Dev. Ind. Pharm. , vol.28 , pp. 1-13
    • Lockman, P.R.1    Mumper, R.J.2    Khan, M.A.3    Allen, D.D.4
  • 29
    • 0344185347 scopus 로고    scopus 로고
    • In situ blood-brain barrier transport of nanoparticles
    • Koziara, J. M., Lockman, P. R., Allen, D. D. & Mumper, R. J. In situ blood-brain barrier transport of nanoparticles. Pharm. Res. 20, 1772-1778 (2003).
    • (2003) Pharm. Res. , vol.20 , pp. 1772-1778
    • Koziara, J.M.1    Lockman, P.R.2    Allen, D.D.3    Mumper, R.J.4
  • 30
    • 0035994314 scopus 로고    scopus 로고
    • Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate
    • Olbrich, C., Gessner, A., Kayser, O. & Muller, R. H. Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate. J. Drug Target. 10, 387-396 (2002).
    • (2002) J. Drug Target. , vol.10 , pp. 387-396
    • Olbrich, C.1    Gessner, A.2    Kayser, O.3    Muller, R.H.4
  • 31
    • 0031765572 scopus 로고    scopus 로고
    • Nanoparticle technology for delivery of drugs across the blood-brain barrier
    • Schroeder, U., Sommerfeld, P., Ulrich, S. & Sabel, B. A. Nanoparticle technology for delivery of drugs across the blood-brain barrier. J. Pharm. Sci. 87, 1305-1307 (1998).
    • (1998) J. Pharm. Sci. , vol.87 , pp. 1305-1307
    • Schroeder, U.1    Sommerfeld, P.2    Ulrich, S.3    Sabel, B.A.4
  • 32
    • 0037335187 scopus 로고    scopus 로고
    • Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
    • Kreuter, J. et al. Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles. Pharm. Res. 20, 409-416 (2003).
    • (2003) Pharm. Res. , vol.20 , pp. 409-416
    • Kreuter, J.1
  • 33
    • 0035937595 scopus 로고    scopus 로고
    • Nanoparticulate systems for brain delivery of drugs
    • Kreuter, J. Nanoparticulate systems for brain delivery of drugs. Adv. Drug Deliv. Rev. 47, 65-81 (2001).
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , pp. 65-81
    • Kreuter, J.1
  • 34
    • 0034887157 scopus 로고    scopus 로고
    • Interaction of poly(butylcyanoacrylate) nanoparticles with the blood-brain barrier in vivo and in vitro
    • Alyaudtin, R. N. et al. Interaction of poly(butylcyanoacrylate) nanoparticles with the blood-brain barrier in vivo and in vitro. J. Drug Target. 9, 209-221 (2001).
    • (2001) J. Drug Target. , vol.9 , pp. 209-221
    • Alyaudtin, R.N.1
  • 35
    • 0036896915 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting
    • Brigger, I. et al. Poly(ethylene glycol)-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting. J. Pharmacol. Exp. Ther. 303, 928-936 (2002).
    • (2002) J. Pharmacol. Exp. Ther. , vol.303 , pp. 928-936
    • Brigger, I.1
  • 36
    • 20744435120 scopus 로고    scopus 로고
    • A relevant in vitro rat model for the evaluation of blood-brain barrier translocation of nanoparticles
    • Garcia-Garcia, E. et al. A relevant in vitro rat model for the evaluation of blood-brain barrier translocation of nanoparticles. Cell. Mol. Life Sci. 62, 1400-1408 (2005).
    • (2005) Cell. Mol. Life Sci. , vol.62 , pp. 1400-1408
    • Garcia-Garcia, E.1
  • 37
    • 0037168963 scopus 로고    scopus 로고
    • Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma
    • Gelperina, S. E. et al. Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma. Toxicol. Lett. 126, 131-141 (2002). Describes a practical example of the delivery of the anticancer drug doxorubicin across the BBB in vivo and illustrates the significant potential these technologies have for drug delivery to the CNS.
    • (2002) Toxicol. Lett. , vol.126 , pp. 131-141
    • Gelperina, S.E.1
  • 38
    • 0035984812 scopus 로고    scopus 로고
    • Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier
    • Kreuter, J. et al. Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier. J. Drug Target. 10, 317-325 (2002).
    • (2002) J. Drug Target. , vol.10 , pp. 317-325
    • Kreuter, J.1
  • 39
    • 0037357723 scopus 로고    scopus 로고
    • Integration of cell culture and microfabrication technology
    • Park, T. H. & Shuler, M. L. Integration of cell culture and microfabrication technology. Biotechnol. Prog. 19, 243-253 (2003).
    • (2003) Biotechnol. Prog. , vol.19 , pp. 243-253
    • Park, T.H.1    Shuler, M.L.2
  • 40
    • 0142084877 scopus 로고    scopus 로고
    • Patterning axonal guidance molecules using a novel strategy for microcontact printing
    • Oliva, A. A. Jr, James, C. D., Kingman, C. E., Craighead, H. G. & Banker, G. A. Patterning axonal guidance molecules using a novel strategy for microcontact printing. Neurochem. Res. 28, 1639-1648 (2003).
    • (2003) Neurochem. Res. , vol.28 , pp. 1639-1648
    • Oliva Jr., A.A.1    James, C.D.2    Kingman, C.E.3    Craighead, H.G.4    Banker, G.A.5
  • 41
    • 1942502193 scopus 로고    scopus 로고
    • Microfabrication and microfluidics for tissue engineering: State of the art and future opportunities
    • Andersson, H. & van den Berg, A. Microfabrication and microfluidics for tissue engineering: state of the art and future opportunities. Lab. Chip 4, 98-103 (2004).
    • (2004) Lab. Chip , vol.4 , pp. 98-103
    • Andersson, H.1    Van Den Berg, A.2
  • 42
    • 0034055302 scopus 로고    scopus 로고
    • Long-term maintenance of patterns of hippocampal pyramidal cells on substrates of polyethylene glycol and microstamped polylysine
    • Branch, D. W., Wheeler, B. C., Brewer, G. J. & Leckband, D. E. Long-term maintenance of patterns of hippocampal pyramidal cells on substrates of polyethylene glycol and microstamped polylysine. IEEE Trans. Biomed. Eng. 47, 290-300 (2000). An excellent example of classical microscale-patterning approaches for controlling the growth and connections of patterned neurons.
    • (2000) IEEE Trans. Biomed. Eng. , vol.47 , pp. 290-300
    • Branch, D.W.1    Wheeler, B.C.2    Brewer, G.J.3    Leckband, D.E.4
  • 43
    • 0033084115 scopus 로고    scopus 로고
    • Microcontact printing for precise control of nerve cell growth in culture
    • Wheeler, B. C., Corey, J. M., Brewer, G. J. & Branch, D. W. Microcontact printing for precise control of nerve cell growth in culture. J. Biomech. Eng. 121, 73-78 (1999).
    • (1999) J. Biomech. Eng. , vol.121 , pp. 73-78
    • Wheeler, B.C.1    Corey, J.M.2    Brewer, G.J.3    Branch, D.W.4
  • 44
    • 0034874431 scopus 로고    scopus 로고
    • Modulation of neural network activity by patterning
    • Chang, J. C., Brewer, G. J. & Wheeler, B. C. Modulation of neural network activity by patterning. Biosens. Bioelectron. 16, 527-533 (2001).
    • (2001) Biosens. Bioelectron. , vol.16 , pp. 527-533
    • Chang, J.C.1    Brewer, G.J.2    Wheeler, B.C.3
  • 45
    • 2942516287 scopus 로고    scopus 로고
    • Atomic force microscopy imaging and pulling of nucleic acids
    • Hansma, H. G., Kasuya, K. & Oroudjev, E. Atomic force microscopy imaging and pulling of nucleic acids. Curr. Opin. Struct. Biol. 14, 380-385 (2004).
    • (2004) Curr. Opin. Struct. Biol. , vol.14 , pp. 380-385
    • Hansma, H.G.1    Kasuya, K.2    Oroudjev, E.3
  • 46
    • 1242271244 scopus 로고    scopus 로고
    • An overview of the biophysical applications of atomic force microscopy
    • Santos, N. C. & Castanho, M. A. An overview of the biophysical applications of atomic force microscopy. Biophys. Chem. 107, 133-149 (2004).
    • (2004) Biophys. Chem. , vol.107 , pp. 133-149
    • Santos, N.C.1    Castanho, M.A.2
  • 47
    • 0642366760 scopus 로고    scopus 로고
    • Engineered nanomaterials for biophotonics applications: Improving sensing, imaging, and therapeutics
    • West, J. L. & Halas, N. J. Engineered nanomaterials for biophotonics applications: improving sensing, imaging, and therapeutics. Annu. Rev. Biomed. Eng. 5, 285-292 (2003).
    • (2003) Annu. Rev. Biomed. Eng. , vol.5 , pp. 285-292
    • West, J.L.1    Halas, N.J.2
  • 48
    • 0036788582 scopus 로고    scopus 로고
    • Optical sensing with quantum dots
    • Murphy, C. J. Optical sensing with quantum dots. Anal. Chem. 74, 520A-526A (2002).
    • (2002) Anal. Chem. , vol.74
    • Murphy, C.J.1
  • 49
    • 0032566763 scopus 로고    scopus 로고
    • Quantum dot bioconjugates for ultrasensitive nonisotopic detection
    • Chan, W. C. & Nie, S. Quantum dot bioconjugates for ultrasensitive nonisotopic detection. Science 281, 2016-2018 (1998).
    • (1998) Science , vol.281 , pp. 2016-2018
    • Chan, W.C.1    Nie, S.2
  • 50
    • 17444429675 scopus 로고    scopus 로고
    • Electron-conducting quantum dot solids: Novel materials based on colloidal semiconductor nanocrystals
    • Vanmaekelbergh, D. & Liljeroth, P. Electron-conducting quantum dot solids: novel materials based on colloidal semiconductor nanocrystals. Chem. Soc. Rev. 34, 299-312 (2005).
    • (2005) Chem. Soc. Rev. , vol.34 , pp. 299-312
    • Vanmaekelbergh, D.1    Liljeroth, P.2
  • 51
    • 0030956033 scopus 로고    scopus 로고
    • Single-particle tracking: Applications to membrane dynamics
    • Saxton, M. J. & Jacobson, K. Single-particle tracking: applications to membrane dynamics. Annu. Rev. Biophys. Biomol. Struct. 26, 373-399 (1997).
    • (1997) Annu. Rev. Biophys. Biomol. Struct. , vol.26 , pp. 373-399
    • Saxton, M.J.1    Jacobson, K.2
  • 52
    • 17144395175 scopus 로고    scopus 로고
    • A multiple target approach for single quantum dot tracking
    • Arlington, Virginia, USA, 15-18 April
    • Bonneau, S., Cohen, L. D. & Dahan, M. A multiple target approach for single quantum dot tracking. IEEE Int. Symp. Biomed Imaging, Arlington, Virginia, USA, 15-18 April, 664-667 (2004).
    • (2004) IEEE Int. Symp. Biomed. Imaging , pp. 664-667
    • Bonneau, S.1    Cohen, L.D.2    Dahan, M.3
  • 53
    • 26444459812 scopus 로고    scopus 로고
    • Single quantum dot tracking based on perceptual grouping using minimal paths in a spatiotemporal volume
    • Bonneau, S., Dahan, M. & Cohen, L. D. Single quantum dot tracking based on perceptual grouping using minimal paths in a spatiotemporal volume. IEEE Trans. Image Process. 14, 1384-1395 (2005).
    • (2005) IEEE Trans. Image Process. , vol.14 , pp. 1384-1395
    • Bonneau, S.1    Dahan, M.2    Cohen, L.D.3
  • 54
    • 17644411099 scopus 로고    scopus 로고
    • Quantum dots in bio-imaging: Revolution by the small
    • Arya, H. et al. Quantum dots in bio-imaging: revolution by the small. Biochem. Biophys. Res. Commun. 329, 1173-1177 (2005).
    • (2005) Biochem. Biophys. Res. Commun. , vol.329 , pp. 1173-1177
    • Arya, H.1
  • 55
    • 0347004627 scopus 로고    scopus 로고
    • In vitro sliding of actin filaments labelled with single quantum dots
    • Mansson, A. et al. In vitro sliding of actin filaments labelled with single quantum dots. Biochem. Biophys. Res. Commun. 314, 529-534 (2004).
    • (2004) Biochem. Biophys. Res. Commun. , vol.314 , pp. 529-534
    • Mansson, A.1
  • 56
    • 0742270981 scopus 로고    scopus 로고
    • Quantum dot ligands provide new insights into erbB/HER receptor-mediated signal transduction
    • Lidke, D. S. et al. Quantum dot ligands provide new insights into erbB/HER receptor-mediated signal transduction. Nature Biotechnol. 22, 198-203 (2004).
    • (2004) Nature Biotechnol. , vol.22 , pp. 198-203
    • Lidke, D.S.1
  • 58
    • 0037225979 scopus 로고    scopus 로고
    • Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots
    • Wu, X. et al. Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots. Nature Biotechnol. 21, 41-46 (2003).
    • (2003) Nature Biotechnol. , vol.21 , pp. 41-46
    • Wu, X.1
  • 59
    • 0037314241 scopus 로고    scopus 로고
    • Lighting up cells with quantum dots
    • Watson, A., Wu, X. & Bruchez, M. Lighting up cells with quantum dots. Biotechniques 34, 296-300, 302-303 (2003).
    • (2003) Biotechniques , vol.34 , pp. 296-300
    • Watson, A.1    Wu, X.2    Bruchez, M.3
  • 60
    • 0042913276 scopus 로고    scopus 로고
    • Development and application of quantum dots for immunocytochemistry of human erythrocytes
    • Tokumasu, F. & Dvorak, J. Development and application of quantum dots for immunocytochemistry of human erythrocytes. J. Microsc. 211, 256-261 (2003).
    • (2003) J. Microsc. , vol.211 , pp. 256-261
    • Tokumasu, F.1    Dvorak, J.2
  • 61
    • 0043246612 scopus 로고    scopus 로고
    • Combined tyramide signal amplification and quantum dots for sensitive and photostable immunofluorescence detection
    • Ness, J. M., Akhtar, R. S., Latham, C. B. & Roth, K. A. Combined tyramide signal amplification and quantum dots for sensitive and photostable immunofluorescence detection. J. Histochem. Cytochem. 51, 981 -987 (2003).
    • (2003) J. Histochem. Cytochem. , vol.51 , pp. 981-987
    • Ness, J.M.1    Akhtar, R.S.2    Latham, C.B.3    Roth, K.A.4
  • 62
    • 0348087040 scopus 로고    scopus 로고
    • Long-term multiple color imaging of live cells using quantum dot bioconjugates
    • Jaiswal, J. K., Mattoussi, H., Mauro, J. M. & Simon, S. M. Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nature Biotechnol. 21, 47-51 (2003).
    • (2003) Nature Biotechnol. , vol.21 , pp. 47-51
    • Jaiswal, J.K.1    Mattoussi, H.2    Mauro, J.M.3    Simon, S.M.4
  • 63
    • 0041424802 scopus 로고    scopus 로고
    • Molecular profiling of single cells and tissue specimens with quantum dots
    • Gao, X. & Nie, S. Molecular profiling of single cells and tissue specimens with quantum dots. Trends Biotechnol. 21, 371-373 (2003).
    • (2003) Trends Biotechnol. , vol.21 , pp. 371-373
    • Gao, X.1    Nie, S.2
  • 64
    • 0036469182 scopus 로고    scopus 로고
    • Luminescent quantum dots for multiplexed biological detection and imaging
    • Chan, W. C. et al. Luminescent quantum dots for multiplexed biological detection and imaging. Curr. Opin. Biotechnol. 13, 40-46 (2002).
    • (2002) Curr. Opin. Biotechnol. , vol.13 , pp. 40-46
    • Chan, W.C.1
  • 66
    • 19944433260 scopus 로고    scopus 로고
    • Quantum dots for live cells, in vivo imaging, and diagnostics
    • Michalet, X. et al. Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307, 538-544 (2005).
    • (2005) Science , vol.307 , pp. 538-544
    • Michalet, X.1
  • 67
    • 27944489615 scopus 로고    scopus 로고
    • In vitro cytotoxicity of nanoparticles in mammalian germ-line stem cells
    • Braydich-Stolle, L., Hussain, S., Schlager, J. & Hofmann, M. C. In vitro cytotoxicity of nanoparticles in mammalian germ-line stem cells. Toxicol. Sci. 88, 412-419 (2005).
    • (2005) Toxicol. Sci. , vol.88 , pp. 412-419
    • Braydich-Stolle, L.1    Hussain, S.2    Schlager, J.3    Hofmann, M.C.4
  • 68
    • 23044459574 scopus 로고    scopus 로고
    • Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots
    • Lovric, J. et al. Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots. J. Mol. Med. 83, 377-385 (2005).
    • (2005) J. Mol. Med. , vol.83 , pp. 377-385
    • Lovric, J.1
  • 69
    • 4644237609 scopus 로고    scopus 로고
    • Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy
    • Voura, E. B., Jaiswal, J. K., Mattoussi, H. & Simon, S. M. Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy. Nature Med. 10, 993-998 (2004).
    • (2004) Nature Med. , vol.10 , pp. 993-998
    • Voura, E.B.1    Jaiswal, J.K.2    Mattoussi, H.3    Simon, S.M.4
  • 70
    • 19044381228 scopus 로고    scopus 로고
    • Collagen nerve conduits - Assessment of biocompatibility and axonal regeneration
    • Stang, F., Fansa, H., Wolf, G. & Keilhoff, G. Collagen nerve conduits - assessment of biocompatibility and axonal regeneration. Biomed. Mater. Eng. 15, 3-12 (2005).
    • (2005) Biomed. Mater. Eng. , vol.15 , pp. 3-12
    • Stang, F.1    Fansa, H.2    Wolf, G.3    Keilhoff, G.4
  • 71
    • 9344237120 scopus 로고    scopus 로고
    • Photofabricated gelatin-based nerve conduits: Nerve tissue regeneration potentials
    • Gamez, E. et al. Photofabricated gelatin-based nerve conduits: nerve tissue regeneration potentials. Cell Transplant. 13, 549-564 (2004).
    • (2004) Cell Transplant. , vol.13 , pp. 549-564
    • Gamez, E.1
  • 72
    • 7444236080 scopus 로고    scopus 로고
    • CNS stem and progenitor cell differentiation into functional neuronal circuits in three-dimensional collagen gels
    • Ma, W. et al. CNS stem and progenitor cell differentiation into functional neuronal circuits in three-dimensional collagen gels. Exp. Neurol. 190, 276-288 (2004).
    • (2004) Exp. Neurol. , vol.190 , pp. 276-288
    • Ma, W.1
  • 73
    • 0036842501 scopus 로고    scopus 로고
    • The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue
    • Park, K. I., Teng, Y. D. & Snyder, E. Y. The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue. Nature Biotechnol. 20, 1111-1117 (2002).
    • (2002) Nature Biotechnol. , vol.20 , pp. 1111-1117
    • Park, K.I.1    Teng, Y.D.2    Snyder, E.Y.3
  • 74
    • 0035105945 scopus 로고    scopus 로고
    • Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures
    • Balgude, A. P., Yu, X., Szymanski, A. & Bellamkonda, R. V. Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures. Biomaterials 22, 1077-1084 (2001).
    • (2001) Biomaterials , vol.22 , pp. 1077-1084
    • Balgude, A.P.1    Yu, X.2    Szymanski, A.3    Bellamkonda, R.V.4
  • 75
    • 0031713951 scopus 로고    scopus 로고
    • The influence of physical structure and charge on neurite extension in a 3D hydrogel scaffold
    • Dillon, G. P., Yu, X., Sridharan, A., Ranieri, J. P. & Bellamkonda, R. V. The influence of physical structure and charge on neurite extension in a 3D hydrogel scaffold. J. Biomater. Sci. Polym. Ed. 9, 1049-1069 (1998).
    • (1998) J. Biomater. Sci. Polym. Ed. , vol.9 , pp. 1049-1069
    • Dillon, G.P.1    Yu, X.2    Sridharan, A.3    Ranieri, J.P.4    Bellamkonda, R.V.5
  • 76
    • 26844583003 scopus 로고    scopus 로고
    • Coil-reinforced hydrogel tubes promote nerve regeneration equivalent to that of nerve autografts
    • 2006
    • Katayama, Y. et al. Coil-reinforced hydrogel tubes promote nerve regeneration equivalent to that of nerve autografts. Biomaterials 27, 505-518 (2006).
    • Biomaterials , vol.27 , pp. 505-518
    • Katayama, Y.1
  • 77
    • 26844526040 scopus 로고    scopus 로고
    • Matrix inclusion within synthetic hydrogel guidance channels improves specific supraspinal and local axonal regeneration after complete spinal cord transection
    • 2006
    • Tsai, E. C., Dalton, P. D., Shoichet, M. S. & Tator, C. H. Matrix inclusion within synthetic hydrogel guidance channels improves specific supraspinal and local axonal regeneration after complete spinal cord transection. Biomaterials 27, 519-533 (2006).
    • Biomaterials , vol.27 , pp. 519-533
    • Tsai, E.C.1    Dalton, P.D.2    Shoichet, M.S.3    Tator, C.H.4
  • 78
    • 23644455504 scopus 로고    scopus 로고
    • Macroporous interconnected dextran scaffolds of controlled porosity for tissue-engineering applications
    • Levesque, S. G., Lim, R. M. & Shoichet, M. S. Macroporous interconnected dextran scaffolds of controlled porosity for tissue-engineering applications. Biomaterials 26, 7436-7446 (2005).
    • (2005) Biomaterials , vol.26 , pp. 7436-7446
    • Levesque, S.G.1    Lim, R.M.2    Shoichet, M.S.3
  • 79
    • 7444267844 scopus 로고    scopus 로고
    • Guided cell adhesion and outgrowth in peptide-modified channels for neural tissue engineering
    • Yu, T. T. & Shoichet, M. S. Guided cell adhesion and outgrowth in peptide-modified channels for neural tissue engineering. Biomaterials 26, 1507-1514 (2005).
    • (2005) Biomaterials , vol.26 , pp. 1507-1514
    • Yu, T.T.1    Shoichet, M.S.2
  • 80
    • 0024443667 scopus 로고
    • A synthetic peptide containing the IKVAV sequence from the A chain of laminin mediates cell attachment, migration, and neurite outgrowth
    • Tashiro, K. et al. A synthetic peptide containing the IKVAV sequence from the A chain of laminin mediates cell attachment, migration, and neurite outgrowth. J. Biol. Chem. 264, 16174-16182 (1989).
    • (1989) J. Biol. Chem. , vol.264 , pp. 16174-16182
    • Tashiro, K.1
  • 81
    • 0029030898 scopus 로고
    • Structure-activity study of a laminin α1 chain active peptide segment Ile-Lys-Val-Ala-Val (IKVAV)
    • Nomizu, M. et al. Structure-activity study of a laminin α1 chain active peptide segment Ile-Lys-Val-Ala-Val (IKVAV). FEBS Lett. 365, 227-231 (1995).
    • (1995) FEBS Lett. , vol.365 , pp. 227-231
    • Nomizu, M.1
  • 82
    • 0034254296 scopus 로고    scopus 로고
    • Neural cell response to multiple novel sites on laminin-1
    • Powell, S. K. et al. Neural cell response to multiple novel sites on laminin-1. J. Neurosci. Res. 61, 302-312 (2000).
    • (2000) J. Neurosci. Res. , vol.61 , pp. 302-312
    • Powell, S.K.1
  • 84
    • 0042388101 scopus 로고    scopus 로고
    • Cerebrometabolic abnormalities in Alzheimer's disease
    • Blass, J. P. Cerebrometabolic abnormalities in Alzheimer's disease. Neurol. Res. 25, 556-566 (2003).
    • (2003) Neurol. Res. , vol.25 , pp. 556-566
    • Blass, J.P.1
  • 85
    • 0033624367 scopus 로고    scopus 로고
    • Neuroprotection, excitotoxicity and NMDA antagonists
    • Gagliardi, R. J. Neuroprotection, excitotoxicity and NMDA antagonists. Arq. Neuropsiquiatr. 58, 583-588 (2000).
    • (2000) Arq. Neuropsiquiatr. , vol.58 , pp. 583-588
    • Gagliardi, R.J.1
  • 86
    • 84984763363 scopus 로고    scopus 로고
    • Mechanisms, challenges and opportunities in stroke
    • Lo, E. H., Dalkara, T. & Moskowitz, M. A. Mechanisms, challenges and opportunities in stroke. Nature Rev. Neurosci. 4, 399-415 (2003).
    • (2003) Nature Rev. Neurosci. , vol.4 , pp. 399-415
    • Lo, E.H.1    Dalkara, T.2    Moskowitz, M.A.3
  • 87
    • 0029923725 scopus 로고    scopus 로고
    • Free radical pathology and antioxidant defense in schizophrenia: A review
    • Mahadik, S. P. & Mukherjee, S. Free radical pathology and antioxidant defense in schizophrenia: a review. Schizophr. Res. 19, 1-17 (1996).
    • (1996) Schizophr. Res. , vol.19 , pp. 1-17
    • Mahadik, S.P.1    Mukherjee, S.2
  • 88
    • 0032906975 scopus 로고    scopus 로고
    • Cellular mechanisms of hypoxic injury in the developing brain
    • Mishra, O. P. & Delivoria-Papadopoulos, M. Cellular mechanisms of hypoxic injury in the developing brain. Brain Res. Bull. 48, 233-238 (1999).
    • (1999) Brain Res. Bull. , vol.48 , pp. 233-238
    • Mishra, O.P.1    Delivoria-Papadopoulos, M.2
  • 89
    • 0034509313 scopus 로고    scopus 로고
    • Photochemistry of supramolecular systems containing C60
    • Gust, D., Moore, T. A. & Moore, A. L. Photochemistry of supramolecular systems containing C60. J. Photochem. Photobiol. B 58, 63-71 (2000).
    • (2000) J. Photochem. Photobiol. B , vol.58 , pp. 63-71
    • Gust, D.1    Moore, T.A.2    Moore, A.L.3
  • 91
    • 15044363147 scopus 로고    scopus 로고
    • Nanobiotechnology: The promise and reality of new approaches to molecular recognition
    • Fortina, P., Kricka, L. J., Surrey, S. & Grodzinski, P. Nanobiotechnology: the promise and reality of new approaches to molecular recognition. Trends Biotechnol. 23, 168-173 (2005).
    • (2005) Trends Biotechnol. , vol.23 , pp. 168-173
    • Fortina, P.1    Kricka, L.J.2    Surrey, S.3    Grodzinski, P.4
  • 92
    • 4944255161 scopus 로고    scopus 로고
    • Methods for the chemical synthesis of fullerenes
    • Scott, L. T. Methods for the chemical synthesis of fullerenes. Angew. Chem. Int. Ed. Engl. 43, 4994-5007 (2004).
    • (2004) Angew. Chem. Int. Ed. Engl. , vol.43 , pp. 4994-5007
    • Scott, L.T.1
  • 93
    • 0035901526 scopus 로고    scopus 로고
    • New concepts in tetrathiafulvalene chemistry
    • Segura, J. L. & Martin, N. New concepts in tetrathiafulvalene chemistry. Angew. Chem. Int. Ed. Engl. 40, 1372-1409 (2001).
    • (2001) Angew. Chem. Int. Ed. Engl. , vol.40 , pp. 1372-1409
    • Segura, J.L.1    Martin, N.2
  • 95
    • 0036166823 scopus 로고    scopus 로고
    • Domain structure and organisation in extracellular matrix proteins
    • Hohenester, E. & Engel, J. Domain structure and organisation in extracellular matrix proteins. Matrix Biol. 21, 115-128 (2002).
    • (2002) Matrix Biol. , vol.21 , pp. 115-128
    • Hohenester, E.1    Engel, J.2
  • 96
    • 3943056896 scopus 로고    scopus 로고
    • Size matters when it comes to safety, report warns
    • Giles, J. Size matters when it comes to safety, report warns. Nature 430, 599 (2004).
    • (2004) Nature , vol.430 , pp. 599
    • Giles, J.1
  • 97
    • 0346096515 scopus 로고    scopus 로고
    • Nanotechnology: What is there to fear from something so small?
    • Giles, J. Nanotechnology: what is there to fear from something so small? Nature 426, 750 (2003).
    • (2003) Nature , vol.426 , pp. 750
    • Giles, J.1
  • 98
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles
    • Oberdorster, G., Oberdorster, E. & Oberdorster, J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect. 113, 823-839 (2005).
    • (2005) Environ. Health Perspect. , vol.113 , pp. 823-839
    • Oberdorster, G.1    Oberdorster, E.2    Oberdorster, J.3
  • 99
    • 0037117498 scopus 로고    scopus 로고
    • Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials
    • Hartgerink, J. D., Beniash, E. & Stupp, S. I. Peptide-amphiphile nanofibers: a versatile scaffold for the preparation of self-assembling materials. Proc. Natl Acad. Sci. USA 99, 5133-5138 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5133-5138
    • Hartgerink, J.D.1    Beniash, E.2    Stupp, S.I.3
  • 100
    • 0035941074 scopus 로고    scopus 로고
    • Self-assembly and mineralization of peptide-amphiphile nanofibers
    • Hartgerink, J. D., Beniash, E. & Stupp, S. I. Self-assembly and mineralization of peptide-amphiphile nanofibers. Science 294, 1684-1688 (2001).
    • (2001) Science , vol.294 , pp. 1684-1688
    • Hartgerink, J.D.1    Beniash, E.2    Stupp, S.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.