메뉴 건너뛰기




Volumn 20, Issue 5-6, 2002, Pages 801-809

Local treatment of brain tumors with targeted chimera cytotoxic proteins

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; CYTOKINE; CYTOTOXIC FACTOR; CYTOTOXIN; CYTOTOXIN A; CYTOTOXIN B; DENILEUKIN DIFTITOX; DIPHTHERIA TOXIN; HORMONE; IMMUNOTOXIN; INTERLEUKIN 13; MONOCLONAL ANTIBODY; PSEUDOMONAS EXOTOXIN; RICIN A; TRANSFERRIN; UNCLASSIFIED DRUG; LIGAND; PROTEIN; TRANSFERRIN RECEPTOR;

EID: 0036053691     PISSN: 07357907     EISSN: None     Source Type: Journal    
DOI: 10.1081/CNV-120003545     Document Type: Review
Times cited : (40)

References (76)
  • 3
    • 0031963921 scopus 로고    scopus 로고
    • Survival rates in patients with primary brain tumors stratified by patient age and tumor histological type: An analysis based on Surveillance, Epidemiology, and End Results (SEER) data, 1973-1991
    • Davis, F.G.; Freels, S.; Grutsch, J.; Barlas, S.; Brem, S. Survival Rates in Patients with Primary Brain Tumors Stratified by Patient Age and Tumor Histological Type: an Analysis Based on Surveillance, Epidemiology, and End Results (SEER) Data, 1973-1991. J. Neurosurg. 1998, 88, 1-10.
    • (1998) J. Neurosurg. , vol.88 , pp. 1-10
    • Davis, F.G.1    Freels, S.2    Grutsch, J.3    Barlas, S.4    Brem, S.5
  • 4
    • 0011902832 scopus 로고
    • Reports from the front
    • Marshall, E. "Reports from the Front" Science, 267, 1995, 1414.
    • (1995) Science , vol.267 , pp. 1414
    • Marshall, E.1
  • 5
    • 0015979018 scopus 로고
    • Infiltration of the leptomeninges by systemic cancer
    • Olson, M.E.; Chernik, N.L.; Posner, J.B. Infiltration of the Leptomeninges by Systemic Cancer. Arch. Neurol. 1974, 30, 122-136.
    • (1974) Arch. Neurol. , vol.30 , pp. 122-136
    • Olson, M.E.1    Chernik, N.L.2    Posner, J.B.3
  • 6
    • 0015291143 scopus 로고
    • Tumor angiogenesis: A quantitative method for histologic grading
    • Brem, S.; Cotran, R.; Folkman, J. Tumor Angiogenesis: a Quantitative Method for Histologic Grading. J. Natl Cancer Inst. 1972, 48, 347-356.
    • (1972) J. Natl. Cancer Inst. , vol.48 , pp. 347-356
    • Brem, S.1    Cotran, R.2    Folkman, J.3
  • 7
    • 0029912659 scopus 로고    scopus 로고
    • Characterization of the human invasion area in the rat intracerebral glioma
    • Ji, Y.; Powers, S.K.; Brown, J.T.; Miner, R. Characterization of the Human Invasion Area in the Rat Intracerebral Glioma. J. Neuro-Oncol. 1996, 30, 189-197.
    • (1996) J. Neuro-Oncol. , vol.30 , pp. 189-197
    • Ji, Y.1    Powers, S.K.2    Brown, J.T.3    Miner, R.4
  • 8
    • 0032729320 scopus 로고    scopus 로고
    • The effect of extent of resection on time to tumor progression and survival in patients with glioblastoma multiforme of the cerebral hemisphere
    • Keles, G.E.; Anderson, B.; Berger, M.S. The Effect of Extent of Resection on Time to Tumor Progression and Survival in Patients with Glioblastoma Multiforme of the Cerebral Hemisphere. Surg. Neurol. 1999, 52, 371-379.
    • (1999) Surg. Neurol. , vol.52 , pp. 371-379
    • Keles, G.E.1    Anderson, B.2    Berger, M.S.3
  • 9
    • 0028266108 scopus 로고
    • Contemporary approaches to the treatment of malignant gliomas with radiation therapy
    • Leibel, S.A.; Scott, C.B.; Loeffler, J.S. Contemporary Approaches to the Treatment of Malignant Gliomas with Radiation Therapy. Semin. Oncol. 1994, 21, 198-219.
    • (1994) Semin. Oncol. , vol.21 , pp. 198-219
    • Leibel, S.A.1    Scott, C.B.2    Loeffler, J.S.3
  • 10
    • 0028353403 scopus 로고
    • The chemotherapy of high-grade astrocytomas
    • Lesser, G.J.; Grossman, S. The Chemotherapy of High-Grade Astrocytomas. Semin. Oncol. 1994, 21, 220-235.
    • (1994) Semin. Oncol. , vol.21 , pp. 220-235
    • Lesser, G.J.1    Grossman, S.2
  • 11
    • 0025688669 scopus 로고
    • Structure, function, and clinical significance of human tumor antigens
    • Herlyn, M.; Menrad, A.; Koprowski, H. Structure, Function, and Clinical Significance of Human Tumor Antigens. J. Natl Cancer Inst. 1990, 82, 1883-1889.
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 1883-1889
    • Herlyn, M.1    Menrad, A.2    Koprowski, H.3
  • 12
    • 0026709285 scopus 로고
    • Monoclonal antibody C242-pseudomonas exotoxin A: A specific and potent immunotoxin with anti-tumor activity on a human colon cancer xenograft in nude mice
    • Debinski, W.; Karlsson, B.; Lindholm, L.; Siegall, C.B.; Willingham, M.C.; FitzGerald, D.; Pastan, I. Monoclonal Antibody C242-Pseudomonas Exotoxin A: A Specific and Potent Immunotoxin with Anti-tumor Activity on a Human Colon Cancer Xenograft in Nude Mice. J. Clin. Investig. 1992, 90, 405-411.
    • (1992) J. Clin. Investig. , vol.90 , pp. 405-411
    • Debinski, W.1    Karlsson, B.2    Lindholm, L.3    Siegall, C.B.4    Willingham, M.C.5    FitzGerald, D.6    Pastan, I.7
  • 13
    • 0021932240 scopus 로고
    • Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
    • Libermann, T.A.; Nusbaum, H.R.; Razon, N.; Kris, R.; Lax, I.; Soreq, H. Amplification, Enhanced Expression and Possible Rearrangement of EGF Receptor Gene in Primary Human Brain Tumours of Glial Origin. Nature 1985, 313, 144-147.
    • (1985) Nature , vol.313 , pp. 144-147
    • Libermann, T.A.1    Nusbaum, H.R.2    Razon, N.3    Kris, R.4    Lax, I.5    Soreq, H.6
  • 14
    • 0026022139 scopus 로고
    • Substitution of foreign protein sequences into a chimeric toxin composed of transforming growth factor α and pseudomonas exotoxin
    • Debinski, W.; Siegall, C.B.; FitzGerald, D.; Pastan, I. Substitution of Foreign Protein Sequences into a Chimeric Toxin Composed of Transforming Growth Factor α and Pseudomonas Exotoxin. Mol. Cell. Biol. 1991, 11, 1751-1753.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1751-1753
    • Debinski, W.1    Siegall, C.B.2    FitzGerald, D.3    Pastan, I.4
  • 15
    • 0027315711 scopus 로고
    • A wide range of human cancers express interleukin 4 (IL4) receptors that can be targeted with chimeric toxin composed of IL4 and pseudomonas exotoxin
    • Debinski, W.; Puri, R.K.; Kreitman, R.J.; Pastan, I. A Wide Range of Human Cancers Express Interleukin 4 (IL4) Receptors that can be Targeted with Chimeric Toxin Composed of IL4 and Pseudomonas Exotoxin. J. Biol. Chem. 1993, 268, 14065-14070.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14065-14070
    • Debinski, W.1    Puri, R.K.2    Kreitman, R.J.3    Pastan, I.4
  • 16
    • 0029041783 scopus 로고
    • A novel chimeric protein composed of interleukin 13 and pseudomonas exotoxin is highly cytotoxic to human carcinoma cells expressing receptors for interleukin 13 and interleukin 4
    • Debinski, W.; Obiri, N.I.; Pastan, I.; Puri, R.K. A Novel Chimeric Protein Composed of Interleukin 13 and Pseudomonas Exotoxin is Highly Cytotoxic to Human Carcinoma Cells Expressing Receptors for Interleukin 13 and Interleukin 4. J. Biol. Chem. 1995, 270, 16775-16780.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16775-16780
    • Debinski, W.1    Obiri, N.I.2    Pastan, I.3    Puri, R.K.4
  • 17
    • 0030832167 scopus 로고    scopus 로고
    • Cell surface localization and density of the tumor-associated variant of the epidermal growth factor receptor, EGFRvIII
    • Wikstrand, C.J.; McLendon, R.E.; Friedman, A.H.; Bigner, D.D. Cell Surface Localization and Density of the Tumor-Associated Variant of the Epidermal Growth Factor Receptor, EGFRvIII. Cancer Res. 1997, 57, 4130-4140.
    • (1997) Cancer Res. , vol.57 , pp. 4130-4140
    • Wikstrand, C.J.1    McLendon, R.E.2    Friedman, A.H.3    Bigner, D.D.4
  • 19
    • 0027421951 scopus 로고
    • Cytotoxicity and antitumor effects of growth factor-toxin fusion proteins on human glioblastoma multiforme cells
    • Kunwar, S.; Pai, L.H.; Pastan, I. Cytotoxicity and Antitumor Effects of Growth Factor-Toxin Fusion Proteins on Human Glioblastoma Multiforme Cells. J. Neurosurg. 1993, 79, 569-576.
    • (1993) J. Neurosurg. , vol.79 , pp. 569-576
    • Kunwar, S.1    Pai, L.H.2    Pastan, I.3
  • 20
    • 0027474795 scopus 로고
    • Efficacy of transferrin receptor-targeted immunotoxins in brain tumor cell lines and pediatric brain tumors
    • Martell, L.A.; Agrawal, A.; Ross, D.A.; Muraszko, K.M. Efficacy of Transferrin Receptor-Targeted Immunotoxins in Brain Tumor Cell Lines and Pediatric Brain Tumors. Cancer Res. 1993, 53, 1348-1353.
    • (1993) Cancer Res. , vol.53 , pp. 1348-1353
    • Martell, L.A.1    Agrawal, A.2    Ross, D.A.3    Muraszko, K.M.4
  • 21
    • 0028332782 scopus 로고
    • Fibroblast growth factor receptor gene expression and immunoreactivity are elevated in human glioblastoma multiforme
    • Morrison, R.S.; Yamaguchi, F.; Bruner, M.M.; Tang, M.; McKeehan, W.; Berger, M.S. Fibroblast Growth Factor Receptor Gene Expression and Immunoreactivity are Elevated in Human Glioblastoma Multiforme. Cancer Res. 1994, 54, 2794-2799.
    • (1994) Cancer Res. , vol.54 , pp. 2794-2799
    • Morrison, R.S.1    Yamaguchi, F.2    Bruner, M.M.3    Tang, M.4    McKeehan, W.5    Berger, M.S.6
  • 22
    • 0039655148 scopus 로고    scopus 로고
    • Exploitation of the antibody repertoire of cancer patients for the identification of human tumor antigens
    • Tureci, O.; Sahin, U.; Zwick, C.; Neumann, F.; Pfreundschuh, M. Exploitation of the Antibody Repertoire of Cancer Patients for the Identification of Human Tumor Antigens. Hybridoma 1999, 18, 23-28.
    • (1999) Hybridoma , vol.18 , pp. 23-28
    • Tureci, O.1    Sahin, U.2    Zwick, C.3    Neumann, F.4    Pfreundschuh, M.5
  • 23
    • 0034184409 scopus 로고    scopus 로고
    • Molecular expression analysis of restrictive receptor for interleukin 13, a brain tumor-associated cancer/testis antigen
    • Debinski, W.; Gibo, D.M. Molecular Expression Analysis of Restrictive Receptor for Interleukin 13, a Brain Tumor-Associated Cancer/Testis Antigen. Mol. Med. 2000, 6, 440-449.
    • (2000) Mol. Med. , vol.6 , pp. 440-449
    • Debinski, W.1    Gibo, D.M.2
  • 24
    • 0014931204 scopus 로고
    • Selective destruction of target cells by diphtheria toxin conjugated to antibody directed against antigen on the cells
    • Moolten, F.L.; Cooperband, S.R. Selective Destruction of Target Cells by Diphtheria Toxin Conjugated to Antibody Directed Against Antigen on the Cells. Science 1970, 169 (July), 68-70.
    • (1970) Science , vol.169 , Issue.JULY , pp. 68-70
    • Moolten, F.L.1    Cooperband, S.R.2
  • 26
    • 0029925934 scopus 로고    scopus 로고
    • Treatment of advanced solid tumors with immunotoxin LMB-1: An antibody linked to pseudomonas exotoxin
    • Pai, L.H.; Wittes, R.; Setser, A.; Willingham, M.C.; Pastan, I. Treatment of Advanced Solid Tumors With Immunotoxin LMB-1: An Antibody Linked to Pseudomonas Exotoxin. Nature Med. 1996, 2, 350-353.
    • (1996) Nature Med. , vol.2 , pp. 350-353
    • Pai, L.H.1    Wittes, R.2    Setser, A.3    Willingham, M.C.4    Pastan, I.5
  • 27
    • 0031451777 scopus 로고    scopus 로고
    • Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors
    • Laske, D.W.; Youle, R.J.; Oldfield, E.H. Tumor Regression with Regional Distribution of the Targeted Toxin TF-CRM107 in Patients with Malignant Brain Tumors. Nature Med. 1997, 3, 1362-1368.
    • (1997) Nature Med. , vol.3 , pp. 1362-1368
    • Laske, D.W.1    Youle, R.J.2    Oldfield, E.H.3
  • 29
    • 0001618425 scopus 로고    scopus 로고
    • Modulation of molecular mechanisms involved in protein synthesis machinery as a new tool for the control of cell proliferation
    • Caraglia, M.; Budillon, A.; Vitale, G.; Lupoli, G.; Tagliaferri, P.; Abbruzzese, A. Modulation of Molecular Mechanisms Involved in Protein Synthesis Machinery as a New Tool for the Control of Cell Proliferation. Eur. J. Biochem. 2000, 267, 3919-3936.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 3919-3936
    • Caraglia, M.1    Budillon, A.2    Vitale, G.3    Lupoli, G.4    Tagliaferri, P.5    Abbruzzese, A.6
  • 30
    • 0028273552 scopus 로고
    • Efficacy of direct intratumoral therapy with targeted protein toxins for solid human gliomas in nude mice
    • Laske, D.W.; Ilercil, O.; Akbasak, A.; Youle, R.J.; Oldfield, E.H. Efficacy of Direct Intratumoral Therapy with Targeted Protein Toxins for Solid Human Gliomas in Nude Mice. J. Neurosurg. 1994, 80, 520-526.
    • (1994) J. Neurosurg. , vol.80 , pp. 520-526
    • Laske, D.W.1    Ilercil, O.2    Akbasak, A.3    Youle, R.J.4    Oldfield, E.H.5
  • 31
    • 0025165507 scopus 로고
    • Potent cytotoxicity of an antihuman transferrin receptor-ricin A-chain immunotoxin on human glioma cells in vitro
    • Recht, L.D.; Griffin, T.W.; Raso, V.; Salimi, A.R. Potent Cytotoxicity of an Antihuman Transferrin Receptor-Ricin A-Chain Immunotoxin on Human Glioma Cells In Vitro. Cancer Res. 1990, 50, 6696-6700,
    • (1990) Cancer Res. , vol.50 , pp. 6696-6700
    • Recht, L.D.1    Griffin, T.W.2    Raso, V.3    Salimi, A.R.4
  • 32
    • 0028859363 scopus 로고
    • Human glioma cells over-express receptor for interleukin 13 and are extremely sensitive to a novel chimeric protein composed of interleukin 13 and pseudomonas exotoxin
    • Debinski, W.; Obiri, N.I.; Powers, S.K.; Pastan, I.; Puri, R.K. Human Glioma Cells Over-Express Receptor for Interleukin 13 and Are Extremely Sensitive to a Novel Chimeric Protein Composed of Interleukin 13 and Pseudomonas Exotoxin. Clin. Cancer Res. 1995, 1, 1253-1258.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 1253-1258
    • Debinski, W.1    Obiri, N.I.2    Powers, S.K.3    Pastan, I.4    Puri, R.K.5
  • 33
    • 0023485290 scopus 로고
    • Redesigning nature's poison to create anti-tumor reagents
    • Vitetta, E.S.; Fulton, R.J.; May, R.D.; Till, M.; Uhr, J.W. Redesigning Nature's Poison to Create Anti-tumor Reagents. Science 1987, 238, 1098-1104.
    • (1987) Science , vol.238 , pp. 1098-1104
    • Vitetta, E.S.1    Fulton, R.J.2    May, R.D.3    Till, M.4    Uhr, J.W.5
  • 34
    • 0039992932 scopus 로고
    • Anti-thy 1.2 monoclonal antibody linked to ricin is a potent cell-type-specific toxin
    • Youle, R.J.; Neville, D.M. Anti-thy 1.2 Monoclonal Antibody Linked to Ricin is a Potent Cell-Type-Specific Toxin. Proc. Natl Acad. Sci. USA 1980, 77, 5483-5486.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 5483-5486
    • Youle, R.J.1    Neville, D.M.2
  • 35
    • 0029044821 scopus 로고
    • Assessment of ganciclovir toxicity to experimental intracranial gliomas following recombinant adenoviral-mediated transfer of the herpes simlex virus thymidine kinase gene by magnetic resonance imaging and proton magnetic resonance spectroscopy
    • Ross, B.D.; Kim, B.; Davidson, B.L. Assessment of Ganciclovir Toxicity to Experimental Intracranial Gliomas Following Recombinant Adenoviral-Mediated Transfer of the Herpes Simlex Virus Thymidine Kinase Gene by Magnetic Resonance Imaging and Proton Magnetic Resonance Spectroscopy. Clin. Cancer Res. 1995, 1, 651-657.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 651-657
    • Ross, B.D.1    Kim, B.2    Davidson, B.L.3
  • 37
    • 0030020689 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of the P53 gene produces rapid and generalized death of human glioma cells via apoptosis
    • Advances in Brief
    • Gomez-Manzano, C.; Fueyo, J.; Kyritsis, A.P.; Steck, P.A.; Roth, J.A.; McDonnell, T.J.; Steck, K.D.; Levin, V.A.; Yung, W.K.A. Adenovirus-Mediated Transfer of the P53 Gene Produces Rapid and Generalized Death of Human Glioma Cells via Apoptosis. Cancer Res. 1996, 56, 694-699, Advances in Brief.
    • (1996) Cancer Res. , vol.56 , pp. 694-699
    • Gomez-Manzano, C.1    Fueyo, J.2    Kyritsis, A.P.3    Steck, P.A.4    Roth, J.A.5    McDonnell, T.J.6    Steck, K.D.7    Levin, V.A.8    Yung, W.K.A.9
  • 38
    • 0029839018 scopus 로고    scopus 로고
    • Receptor for IL 13 does not interact with IL4 but receptor for IL4 interacts with IL13 on human glioma cells
    • Debinski, W.; Miner, R.; Obiri, N.I.; Puri, R.K. Receptor for IL 13 does Not Interact with IL4 but Receptor for IL4 Interacts with IL13 on human Glioma Cells. J. Biol. Chem. 1996, 271, 22428-22433.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22428-22433
    • Debinski, W.1    Miner, R.2    Obiri, N.I.3    Puri, R.K.4
  • 39
    • 0032394928 scopus 로고    scopus 로고
    • Role of caspases in immunotoxin-induced apoptosis of cancer cells
    • Keppler-Hafkemeyer, A.; Brinkmann, U.; Pastan, I. Role of Caspases in Immunotoxin-Induced Apoptosis of Cancer Cells. Biochemistry 1998, 37 (48), 16934-16942.
    • (1998) Biochemistry , vol.37 , Issue.48 , pp. 16934-16942
    • Keppler-Hafkemeyer, A.1    Brinkmann, U.2    Pastan, I.3
  • 40
    • 0034119870 scopus 로고    scopus 로고
    • Apoptosis induced by immunotoxins used in the treatment of hematologic malignancies
    • Keppler-Hafkemeyer, A.; Kreitman, R.J.; Pastan, I. Apoptosis Induced by Immunotoxins used in the Treatment of Hematologic Malignancies. Int. J. Cancer 2000, 87, 86-94.
    • (2000) Int. J. Cancer , vol.87 , pp. 86-94
    • Keppler-Hafkemeyer, A.1    Kreitman, R.J.2    Pastan, I.3
  • 41
    • 0029151759 scopus 로고
    • Recombinant F(ab) C242-pseudomonas exotoxin, but not the whole antibody-based immunotoxin, causes regression of a human colorectal tumor xenograft
    • Debinski, W.; Pastan, I. Recombinant F(ab) C242-Pseudomonas Exotoxin, But Not the Whole Antibody-Based Immunotoxin, Causes Regression of a Human Colorectal Tumor Xenograft. Clin. Cancer Res. 1995, 1, 1015-1022.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 1015-1022
    • Debinski, W.1    Pastan, I.2
  • 42
    • 0026688453 scopus 로고
    • Monovalent immunotoxin containing truncated form of pseudomonas exotoxin as potent antitumor agent
    • Debinski, W.; Pastan, I. Monovalent Immunotoxin Containing Truncated Form of Pseudomonas Exotoxin as Potent Antitumor Agent. Cancer Res. 1992, 52, 5379-5385,
    • (1992) Cancer Res. , vol.52 , pp. 5379-5385
    • Debinski, W.1    Pastan, I.2
  • 43
    • 0032403273 scopus 로고    scopus 로고
    • Recombinant Fv immunotoxins and Fv fragments as novel agents for cancer therapy and diagnosis
    • Reiter, Y.; Pastan, I, Recombinant Fv Immunotoxins and Fv Fragments as Novel Agents for Cancer Therapy and Diagnosis. Trends Biotechnol. 1998, 16, 513-520.
    • (1998) Trends Biotechnol. , vol.16 , pp. 513-520
    • Reiter, Y.1    Pastan, I.2
  • 44
    • 0000838807 scopus 로고
    • NAD-dependent inhibition of protein synthesis by pseudomonas aeruginosa toxin
    • Iglewski, B.H.; Kabat, D. NAD-Dependent Inhibition of Protein Synthesis by Pseudomonas aeruginosa Toxin. Proc. Natl Acad. Sci., USA 1975, 72, 2284-2288.
    • (1975) Proc. Natl. Acad. Sci., USA , vol.72 , pp. 2284-2288
    • Iglewski, B.H.1    Kabat, D.2
  • 46
    • 0030447660 scopus 로고    scopus 로고
    • Brain drug delivery of small molecules using immunoliposomes
    • Huwyler, J.; Dafang, W.; Pardridge, W.M. Brain Drug Delivery of Small Molecules Using Immunoliposomes. Proc. Natl Acad. Sci. USA 1996, 93, 14164-14169.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14164-14169
    • Huwyler, J.1    Dafang, W.2    Pardridge, W.M.3
  • 47
    • 0014739014 scopus 로고
    • Capillary ultrastructure and the blood-brain barrier in human malignant brain tumors
    • Long, D.M, Capillary Ultrastructure and the Blood-Brain Barrier in Human Malignant Brain Tumors. J. Neurosurg. 1970, 32, 127-144.
    • (1970) J. Neurosurg. , vol.32 , pp. 127-144
    • Long, D.M.1
  • 48
    • 0030947678 scopus 로고    scopus 로고
    • Intratumoral infusion of the monoclonal antibody, mAb 425, against the epidermal-growth-factor receptor in patients with advanced malignant glioma
    • Wersall, P.; Ohlsson, I.; Biberfeld, P.; Collins, V.; von Krusenstjerna; Larsson, S.; Mellstebt, H.; Boethims, J. Intratumoral Infusion of the Monoclonal Antibody, mAb 425, Against the Epidermal-Growth-Factor Receptor in Patients with Advanced Malignant Glioma. Cancer Immunol. Immunother. 1997, 44, 157-164.
    • (1997) Cancer Immunol. Immunother. , vol.44 , pp. 157-164
    • Wersall, P.1    Ohlsson, I.2    Biberfeld, P.3    Collins, V.4    Von Krusenstjerna5    Larsson, S.6    Mellstebt, H.7    Boethims, J.8
  • 49
    • 0031238701 scopus 로고    scopus 로고
    • Effects of needle insertion in tumors on interstitial fluid pressure
    • Griffon-Etienne, G.; Boucher, Y.; Jain, R.K.; Suite, H.D. Effects of Needle Insertion in Tumors on Interstitial Fluid Pressure. Microvasc. Res. 1997, 54, 174-177,
    • (1997) Microvasc. Res. , vol.54 , pp. 174-177
    • Griffon-Etienne, G.1    Boucher, Y.2    Jain, R.K.3    Suite, H.D.4
  • 50
    • 0033616693 scopus 로고    scopus 로고
    • Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome
    • Baluna, R.; Rizo, J.; Gordon, B.E.; Ghetie, V.; Vitetta, E.S. Evidence for a Structural Motif in Toxins and Interleukin-2 that May Be Responsible for Binding to Endothelial Cells and Initiating Vascular Leak Syndrome. Proc. Natl Acad. Sci. USA 1999, 96, 3957-3962.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3957-3962
    • Baluna, R.1    Rizo, J.2    Gordon, B.E.3    Ghetie, V.4    Vitetta, E.S.5
  • 51
    • 0022508973 scopus 로고
    • The distribution of transferrin immunoreactivity in the rat central nervous system
    • Connor, J.R.; Fine, R.E. The Distribution of Transferrin Immunoreactivity in the Rat Central Nervous System. Brain Res. 1986, 368, 319-328.
    • (1986) Brain Res. , vol.368 , pp. 319-328
    • Connor, J.R.1    Fine, R.E.2
  • 52
    • 0000819723 scopus 로고
    • Transferrin receptor in rat brain: Neuropeptide-like pattern and relationship to iron distribution
    • Hill, J.M.; Ruff, M.R.; Weber, R.J.; Pert, C.B. Transferrin Receptor in Rat Brain: Neuropeptide-Like Pattern and Relationship to Iron Distribution. Proc. Natl Acad. Sci. USA 1985, 82, 4553-4557.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 4553-4557
    • Hill, J.M.1    Ruff, M.R.2    Weber, R.J.3    Pert, C.B.4
  • 53
    • 0033781254 scopus 로고    scopus 로고
    • Expression of a restrictive receptor for interleukin 13 is associated with glial transformation
    • Debinski, W.; Slagle, B.; Gibo, D.M.; Powers, S.K.; Gillespie, G.Y. Expression of a Restrictive Receptor for Interleukin 13 Is Associated with Glial Transformation. J. Neuro-Oncol. 2000, 48, 103-111.
    • (2000) J. Neuro-Oncol. , vol.48 , pp. 103-111
    • Debinski, W.1    Slagle, B.2    Gibo, D.M.3    Powers, S.K.4    Gillespie, G.Y.5
  • 54
    • 0023194662 scopus 로고
    • Potent and specific killing of human maligant brain tumor cells by an anti-transferrin receptor antibody-ricin immunotoxin
    • Zovickian, J.; Johnson, V.G.; Youle, R.J. Potent and Specific Killing of Human Maligant Brain Tumor Cells by an Anti-transferrin Receptor Antibody-Ricin Immunotoxin. J. Neurosurg. 1987, 66, 850-861.
    • (1987) J. Neurosurg. , vol.66 , pp. 850-861
    • Zovickian, J.1    Johnson, V.G.2    Youle, R.J.3
  • 55
    • 0025298818 scopus 로고
    • Transferrin receptor in normal and neoplastic brain tissue: Implications for brain-tumor immunotherapy
    • Recht, L.; Torres, C.O.; Smith, T.W.; Raso, V.; Griffin, T.W. Transferrin Receptor in Normal and Neoplastic Brain Tissue: Implications for Brain-Tumor Immunotherapy. J. Neurosurg. 1990, 72, 941-945.
    • (1990) J. Neurosurg. , vol.72 , pp. 941-945
    • Recht, L.1    Torres, C.O.2    Smith, T.W.3    Raso, V.4    Griffin, T.W.5
  • 56
    • 0027474795 scopus 로고
    • Efficacy of transferrin receptor-targeted immunotoxins in brain tumor cell lines and pediatric brain tumors
    • Martell, L.A.; Agrawal, A.; Ross, D.A.; Muraszko, K.M. Efficacy of Transferrin Receptor-Targeted Immunotoxins in Brain Tumor Cell Lines and Pediatric Brain Tumors. Cancer Res. 1993, 53, 1348-1353.
    • (1993) Cancer Res. , vol.53 , pp. 1348-1353
    • Martell, L.A.1    Agrawal, A.2    Ross, D.A.3    Muraszko, K.M.4
  • 58
    • 0031969574 scopus 로고    scopus 로고
    • Novel way to increase targeting specificity to a human glioblastoma-associated receptor for interleukin 13
    • Debinski, W.; Miner, R.; Gibo, D.; Puri, R.K. Novel Way to Increase Targeting Specificity to a Human Glioblastoma-Associated Receptor for Interleukin 13. Int. J. Cancer 1998, 76, 547-551.
    • (1998) Int. J. Cancer , vol.76 , pp. 547-551
    • Debinski, W.1    Miner, R.2    Gibo, D.3    Puri, R.K.4
  • 61
    • 0029057002 scopus 로고
    • Immunotoxins that target an oncogenic mutant epidermal growth factor receptor expressed in human tumors
    • Lorimer, I.A.; Wikstrand, C.J.; Batra, S.K.; Bigner, D.D.; Pastan, I. Immunotoxins that Target an Oncogenic Mutant Epidermal Growth Factor Receptor Expressed in Human Tumors. Clin. Cancer Res. 1995, 1, 859-864.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 859-864
    • Lorimer, I.A.1    Wikstrand, C.J.2    Batra, S.K.3    Bigner, D.D.4    Pastan, I.5
  • 64
    • 0028084025 scopus 로고
    • An immunotoxin with increased activity and homogeneity produced by reducing the number of lysine residues in recombinant pseudomonas exotoxin
    • Debinski, W.; Pastan, I. An Immunotoxin with Increased Activity and Homogeneity Produced by Reducing the Number of Lysine Residues in Recombinant Pseudomonas Exotoxin. Bioconjug. Chem. 1994, 5, 40-46.
    • (1994) Bioconjug. Chem. , vol.5 , pp. 40-46
    • Debinski, W.1    Pastan, I.2
  • 65
    • 0032455431 scopus 로고    scopus 로고
    • An immune regulatory cytokine receptor and glioblastoma multiforme: An unexpected link
    • Debinski, W. An Immune Regulatory Cytokine Receptor and Glioblastoma Multiforme: An Unexpected Link. Crit. Rev. Oncogen. 1998, 9, 255-268.
    • (1998) Crit. Rev. Oncogen. , vol.9 , pp. 255-268
    • Debinski, W.1
  • 66
    • 0031898505 scopus 로고    scopus 로고
    • Novel anti-brain tumor cytotoxins specific for cancer cells
    • Debinski, W.; Gibo, D.M.; Kealiher, A.; Puri, R.K. Novel Anti-brain Tumor Cytotoxins Specific for Cancer Cells. Nature Biotcchnol. 1998, 16, 449-453.
    • (1998) Nature Biotechnol. , vol.16 , pp. 449-453
    • Debinski, W.1    Gibo, D.M.2    Kealiher, A.3    Puri, R.K.4
  • 67
    • 0032901749 scopus 로고    scopus 로고
    • Receptor for interleukin 13 is a marker and therapeutic target for human high-grade gliomas
    • Debinski, W.; Gibo, D.M.; Hulet, S.W.; Connor, J.R.; Gillespie, G.Y. Receptor for Interleukin 13 is a Marker and Therapeutic Target for Human High-Grade Gliomas. Clin. Cancer Res. 1999, 5, 985-990.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 985-990
    • Debinski, W.1    Gibo, D.M.2    Hulet, S.W.3    Connor, J.R.4    Gillespie, G.Y.5
  • 68
    • 0033190674 scopus 로고    scopus 로고
    • Receptor for interleukin 13 is abundantly and specifically over-expressed in patients with glioblastoma multiforme
    • Debinski, W.; Gibo, D.M.; Slagle, B.; Powers, S.K.; Gillespie, G.Y. Receptor for Interleukin 13 is Abundantly and Specifically Over-expressed in Patients with Glioblastoma Multiforme. Int. J. Oncol. 1999, 15, 481-486.
    • (1999) Int. J. Oncol. , vol.15 , pp. 481-486
    • Debinski, W.1    Gibo, D.M.2    Slagle, B.3    Powers, S.K.4    Gillespie, G.Y.5
  • 69
    • 0141716980 scopus 로고    scopus 로고
    • Rationally designed multiply mutated interleukin 13-based cytotoxins for the treatment of gliomas
    • Debinski, W.; Nash, K.T.; Thompson, J.P. Rationally Designed Multiply Mutated Interleukin 13-Based Cytotoxins for the Treatment of Gliomas. Neuro-Oncology 2000, 2, 259.
    • (2000) Neuro-Oncology , vol.2 , pp. 259
    • Debinski, W.1    Nash, K.T.2    Thompson, J.P.3
  • 70
    • 0033993651 scopus 로고    scopus 로고
    • Cancer genetics/epigenetics and the X chromosome: Possible new links for malignant glioma pathogenesis and immune-based therapies
    • Mintz, A.; Debinski, W. Cancer Genetics/Epigenetics and the X Chromosome: Possible New Links for Malignant Glioma Pathogenesis and Immune-Based Therapies. Crit. Rev. Oncogen. 2000, 11, 77-95.
    • (2000) Crit. Rev. Oncogen. , vol.11 , pp. 77-95
    • Mintz, A.1    Debinski, W.2
  • 71
    • 0029927153 scopus 로고    scopus 로고
    • Cloning and characterization of a specific interleukin (Il)-13 binding protein structurally related to the IL-5 receptor α chain
    • Caput, D.; Laurent, P.; Kaghad, M.; Lelias, J.-M.; Lefort, S.; Vita, N.; Ferrara, P. Cloning and Characterization of a Specific Interleukin (IL)-13 Binding Protein Structurally Related to the IL-5 Receptor α Chain. J. Biol. Chem. 1996, 271, 16921-16926.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16921-16926
    • Caput, D.1    Laurent, P.2    Kaghad, M.3    Lelias, J.-M.4    Lefort, S.5    Vita, N.6    Ferrara, P.7
  • 72
    • 0030068217 scopus 로고    scopus 로고
    • Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
    • Hilton, D.J.; Zhang, J.-G.; Metcalf, D.; Alexander, W.S.; Nicola, N.A.; Wilson, T.A. Cloning and Characterization of a Binding Subunit of the Interleukin 13 Receptor That is Also a Component of the Interleukin 4 Receptor. Proc. Natl Acad. Sci. USA 1996, 93, 497-501.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 497-501
    • Hilton, D.J.1    Zhang, J.-G.2    Metcalf, D.3    Alexander, W.S.4    Nicola, N.A.5    Wilson, T.A.6
  • 73
    • 0027274890 scopus 로고
    • Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction
    • Zurawski, S.M.; Vega, F., Jr.; Huyghe, B.; Zurawski, G. Receptors for Interleukin-13 and Interleukin-4 Are Complex and Share a Novel Component That Functions in Signal Transduction. EMBO J. 1993, 12, 2663-2670.
    • (1993) EMBO J. , vol.12 , pp. 2663-2670
    • Zurawski, S.M.1    Vega F., Jr.2    Huyghe, B.3    Zurawski, G.4
  • 74
    • 0031570315 scopus 로고    scopus 로고
    • Chromosome mapping and expression of the human interleukin-13 receptor
    • Guo, J.; Apiou, F.; Mellerin, M.-P.; Lebeau, B.; Jacques, Y.; Minvielle, S. Chromosome Mapping and Expression of the Human Interleukin-13 Receptor. Genomics 1997, 42, 141-145.
    • (1997) Genomics , vol.42 , pp. 141-145
    • Guo, J.1    Apiou, F.2    Mellerin, M.-P.3    Lebeau, B.4    Jacques, Y.5    Minvielle, S.6
  • 76
    • 0028350677 scopus 로고
    • Interstitial taxol delivered from a biodegradable polymer implant against experimental malignant glioma
    • Walter, K.A.; Cahan, M.A.; Gur, A.; Tyler, B.; Hilton, J.; Colvin, O.M.; Burger, P.C.; Domb, A.; Brem, H. Interstitial Taxol Delivered from a Biodegradable Polymer Implant Against Experimental Malignant Glioma. Cancer Res. 1994, 54, 2207-2212.
    • (1994) Cancer Res. , vol.54 , pp. 2207-2212
    • Walter, K.A.1    Cahan, M.A.2    Gur, A.3    Tyler, B.4    Hilton, J.5    Colvin, O.M.6    Burger, P.C.7    Domb, A.8    Brem, H.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.