Mechanisms of disease: Regulation of glucocorticoid and receptor levels - Impact on the metabolic syndrome

Nature Clinical Practice Endocrinology and Metabolism

Volumn 2, Issue 11, 2006, Pages 621-631

  Witchel, Selma F ^a   DeFranco, Donald B ^b  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

11 hydroxysteroid dehydrogenase; Downregulation; Glucocorticoid receptor; Glucocorticoids; Metabolic syndrome

Indexed keywords

GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR;

CYTOPLASM; DISEASE COURSE; DOWN REGULATION; HUMAN; LIVER; METABOLIC SYNDROME X; MOLECULAR DYNAMICS; MUSCLE; NONHUMAN; PANCREAS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; REVIEW;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; FETAL DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOCORTICOIDS; HUMANS; INFLAMMATION; LIVER; METABOLIC SYNDROME X; MODELS, BIOLOGICAL; MUSCLES; OBESITY; ORGAN SPECIFICITY; PANCREAS; POLYMORPHISM, GENETIC; PROTEIN DENATURATION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, GLUCOCORTICOID;

EID: 33750620067     PISSN: 17458366     EISSN: 17458374     Source Type: Journal    
DOI: 10.1038/ncpendmet0323     Document Type: Review

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