-
1
-
-
0035190026
-
Cellular function of phosphoinositide 3-kinases: Implications for development, homeostasis, and cancer
-
Katso R, Okkenhaug K, Ahmadi K, White S, Timms J, Waterfield MD. Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer. Annu Rev Cell Dev Biol 2001;17:615-75.
-
(2001)
Annu Rev Cell Dev Biol
, vol.17
, pp. 615-675
-
-
Katso, R.1
Okkenhaug, K.2
Ahmadi, K.3
White, S.4
Timms, J.5
Waterfield, M.D.6
-
2
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
Samuels Y, Wang Z, Bardelli A, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004;304:554.
-
(2004)
Science
, vol.304
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
-
3
-
-
3442878125
-
Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas
-
Broderick DK, Di C, Parrett TJ, et al. Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas. Cancer Res 2004;64:5048-50.
-
(2004)
Cancer Res
, vol.64
, pp. 5048-5050
-
-
Broderick, D.K.1
Di, C.2
Parrett, T.J.3
-
4
-
-
7444250290
-
Mutation of the PIK3CA gene in ovarian and breast cancer
-
Campbell IG, Russell SE, Choong DY, et al. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res 2004;64:7678-81.
-
(2004)
Cancer Res
, vol.64
, pp. 7678-7681
-
-
Campbell, I.G.1
Russell, S.E.2
Choong, D.Y.3
-
5
-
-
28544452359
-
Mutation of the PIK3CA gene in anaplastic thyroid cancer
-
Garcia-Rostan G, Costa AM, Pereira-Castro I, et al. Mutation of the PIK3CA gene in anaplastic thyroid cancer. Cancer Res 2005;65:10199-207.
-
(2005)
Cancer Res
, vol.65
, pp. 10199-10207
-
-
Garcia-Rostan, G.1
Costa, A.M.2
Pereira-Castro, I.3
-
6
-
-
20044388328
-
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas
-
Lee JW, Soung YH, Kim SY, et al. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 2005;24:1477-80.
-
(2005)
Oncogene
, vol.24
, pp. 1477-1480
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
-
7
-
-
17144382038
-
Frequent mutation of the PIK3CA gene in ovarian and breast cancers
-
Levine DA, Bogomolniy F, Yee CJ, et al. Frequent mutation of the PIK3CA gene in ovarian and breast cancers. Clin Cancer Res 2005;11:2875-8.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2875-2878
-
-
Levine, D.A.1
Bogomolniy, F.2
Yee, C.J.3
-
8
-
-
28244490997
-
High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma
-
Oda K, Stokoe D, Taketani Y, McCormick F. High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma. Cancer Res 2005;65:10669-73.
-
(2005)
Cancer Res
, vol.65
, pp. 10669-10673
-
-
Oda, K.1
Stokoe, D.2
Taketani, Y.3
McCormick, F.4
-
9
-
-
24144452026
-
PIK3CA mutations in advanced ovarian carcinomas
-
Wang Y, Helland A, Holm R, Kristensen GB, Borresen-Dale AL. PIK3CA mutations in advanced ovarian carcinomas. Hum Mutat 2005;25:322.
-
(2005)
Hum Mutat
, vol.25
, pp. 322
-
-
Wang, Y.1
Helland, A.2
Holm, R.3
Kristensen, G.B.4
Borresen-Dale, A.L.5
-
10
-
-
22144493794
-
PIK3CA mutations in glioblastoma multiforme
-
Hartmann C, Bartels G, Gehlhaar C, Holtkamp N, von Deimling A. PIK3CA mutations in glioblastoma multiforme. Acta Neuropathol (Berl) 2005;109:639-42.
-
(2005)
Acta Neuropathol (Berl)
, vol.109
, pp. 639-642
-
-
Hartmann, C.1
Bartels, G.2
Gehlhaar, C.3
Holtkamp, N.4
Von Deimling, A.5
-
11
-
-
22144461014
-
Mutations of the PIK3CA gene are rare in human glioblastoma
-
Mueller W, Mizoguchi M, Silen E, D'Amore K, Nutt CL, Louis DN. Mutations of the PIK3CA gene are rare in human glioblastoma. Acta Neuropathol (Berl) 2005;109:654-5.
-
(2005)
Acta Neuropathol (Berl)
, vol.109
, pp. 654-655
-
-
Mueller, W.1
Mizoguchi, M.2
Silen, E.3
D'Amore, K.4
Nutt, C.L.5
Louis, D.N.6
-
12
-
-
25144522599
-
Genetic alteration and expression of the phosphoinositol-3-kinase/Akt pathway genes P1K3CA and PIKE in human glioblastomas
-
Knobbe CB, Trampe-Kieslich A, Reifenberger G. Genetic alteration and expression of the phosphoinositol-3-kinase/Akt pathway genes P1K3CA and PIKE in human glioblastomas. Neuropathol Appl Neurobiol 2005;31:486-90.
-
(2005)
Neuropathol Appl Neurobiol
, vol.31
, pp. 486-490
-
-
Knobbe, C.B.1
Trampe-Kieslich, A.2
Reifenberger, G.3
-
13
-
-
20144387695
-
PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma
-
Saal LH, Holm K, Maurer M, et al. PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. Cancer Res 2005;65:2554-9.
-
(2005)
Cancer Res
, vol.65
, pp. 2554-2559
-
-
Saal, L.H.1
Holm, K.2
Maurer, M.3
-
14
-
-
0034221629
-
Identification of PATCHED mutations in medulloblastomas by direct sequencing
-
Dong J, Gailani MR, Pomeroy SL, Reardon D, Bale AE. Identification of PATCHED mutations in medulloblastomas by direct sequencing. Hum Mutat 2000;16:89-90.
-
(2000)
Hum Mutat
, vol.16
, pp. 89-90
-
-
Dong, J.1
Gailani, M.R.2
Pomeroy, S.L.3
Reardon, D.4
Bale, A.E.5
-
15
-
-
18444394315
-
Comparison of DNA- and RNA-based methods for detection of truncating BRCA1 mutations
-
Andrulis IL, Anton-Culver H, Beck J, et al. Comparison of DNA- and RNA-based methods for detection of truncating BRCA1 mutations. Hum Mutat 2002;20:65-73.
-
(2002)
Hum Mutat
, vol.20
, pp. 65-73
-
-
Andrulis, I.L.1
Anton-Culver, H.2
Beck, J.3
-
16
-
-
31944444234
-
Cancer-specific mutations in PIK3CA are oncogenic in vivo
-
Bader AG, Kang S, Vogt PK. Cancer-specific mutations in PIK3CA are oncogenic in vivo. Proc Natl Acad Sci U S A 2006;103:1475-9.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 1475-1479
-
-
Bader, A.G.1
Kang, S.2
Vogt, P.K.3
-
17
-
-
21144457217
-
Functional analysis of PIK3CA gene mutations in human colorectal cancer
-
Ikenoue T, Kanai F, Hikiba Y, et al. Functional analysis of PIK3CA gene mutations in human colorectal cancer. Cancer Res 2005;65:4562-7.
-
(2005)
Cancer Res
, vol.65
, pp. 4562-4567
-
-
Ikenoue, T.1
Kanai, F.2
Hikiba, Y.3
-
18
-
-
14144252004
-
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic
-
Kang S, Bader AG, Vogt PK. Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. Proc Natl Acad Sci U S A 2005;102:802-7.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 802-807
-
-
Kang, S.1
Bader, A.G.2
Vogt, P.K.3
-
19
-
-
20444374445
-
Mutant PIK3CA promotes cell growth and invasion of human cancer cells
-
Samuels Y, Diaz LA, Jr., Schmidt-Kittler O, et al. Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Cancer Cell 2005;7:561-73.
-
(2005)
Cancer Cell
, vol.7
, pp. 561-573
-
-
Samuels, Y.1
Diaz Jr., L.A.2
Schmidt-Kittler, O.3
-
20
-
-
29444449785
-
The oncogenic properties of mutant p110α and p110β phosphatidylinositol 3-kinases in human mammary epithelial cells
-
Zhao JJ, Liu Z, Wang L, Shin E, Loda MF, Roberts TM. The oncogenic properties of mutant p110α and p110β phosphatidylinositol 3-kinases in human mammary epithelial cells. Proc Natl Acad Sci USA 2005;102:18443-8.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18443-18448
-
-
Zhao, J.J.1
Liu, Z.2
Wang, L.3
Shin, E.4
Loda, M.F.5
Roberts, T.M.6
-
21
-
-
27544515272
-
Somatic mutation and gain of copy number of PIK3CA in human breast cancer
-
Wu G, Xing M, Mambo E, et al. Somatic mutation and gain of copy number of PIK3CA in human breast cancer. Breast Cancer Res 2005;7:R609-16.
-
(2005)
Breast Cancer Res
, vol.7
-
-
Wu, G.1
Xing, M.2
Mambo, E.3
-
22
-
-
26444481568
-
Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas
-
Rand V, Huang J, Stockwell T, et al. Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas. Proc Natl Acad Sci U S A 2005;102:14344-9.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 14344-14349
-
-
Rand, V.1
Huang, J.2
Stockwell, T.3
-
23
-
-
0034998193
-
Detection of multiple gene amplifications in glioblastoma multiforme using array-based comparative gcnomic hybridization
-
Hui AB, Lo KW, Yin XL, Poon WS, Ng HK. Detection of multiple gene amplifications in glioblastoma multiforme using array-based comparative gcnomic hybridization. Lab Invest 2001;81:717-23.
-
(2001)
Lab Invest
, vol.81
, pp. 717-723
-
-
Hui, A.B.1
Lo, K.W.2
Yin, X.L.3
Poon, W.S.4
Ng, H.K.5
-
24
-
-
8744259822
-
Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas
-
Mizoguchi M, Nun CL, Mohapatra G, Louis DN. Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas. Brain Pathol 2004;14:372-7.
-
(2004)
Brain Pathol
, vol.14
, pp. 372-377
-
-
Mizoguchi, M.1
Nun, C.L.2
Mohapatra, G.3
Louis, D.N.4
-
25
-
-
0242499482
-
Genetic alterations and aberrant expression of genes related to the phosphatidyl-inositol-3′-kinase/protein kinase B (Akt) signal transduction pathway in glioblastomas
-
Knobbe CB, Reifenberger G. Genetic alterations and aberrant expression of genes related to the phosphatidyl-inositol-3′-kinase/protein kinase B (Akt) signal transduction pathway in glioblastomas. Brain Pathol 2003;13:507-18.
-
(2003)
Brain Pathol
, vol.13
, pp. 507-518
-
-
Knobbe, C.B.1
Reifenberger, G.2
-
26
-
-
0001843063
-
Glioblastoma
-
Kleihues P, Cavenee WK, editors. Lyon: IARC Press
-
Kleihues P, Burger PC, Collins VP, Newcomb EW, Ohgaki H, Cavenee WK. Glioblastoma. In: Kleihues P, Cavenee WK, editors. Pathology and genetics of tumours of the nervous system. Lyon: IARC Press; 2000. p. 29-39.
-
(2000)
Pathology and Genetics of Tumours of the Nervous System
, pp. 29-39
-
-
Kleihues, P.1
Burger, P.C.2
Collins, V.P.3
Newcomb, E.W.4
Ohgaki, H.5
Cavenee, W.K.6
|