-
1
-
-
0030799706
-
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
-
Stokoe D, Stephens LR, Copeland T, et al. Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. Science 1997;277:567-70.
-
(1997)
Science
, vol.277
, pp. 567-570
-
-
Stokoe, D.1
Stephens, L.R.2
Copeland, T.3
-
2
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
Stambolic V, Suzuki A, de la Pompa JL, et al. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 1998;95:29-39.
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
De La Pompa, J.L.3
-
3
-
-
84984777123
-
PTEN1 is frequently mutated in primary endometrial carcinomas
-
Kong D, Suzuki A, Zou TT, et al. PTEN1 is frequently mutated in primary endometrial carcinomas. Nat Genet 1997;17:143-4.
-
(1997)
Nat Genet
, vol.17
, pp. 143-144
-
-
Kong, D.1
Suzuki, A.2
Zou, T.T.3
-
4
-
-
0034802755
-
PTEN mutation located only outside exons 5, 6, and 7 is an independent predictor of favorable survival in endometrial carcinomas
-
Minaguchi T, Yoshikawa H, Oda K, et al. PTEN mutation located only outside exons 5, 6, and 7 is an independent predictor of favorable survival in endometrial carcinomas. Clin Cancer Res 2001;7:2636-42.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2636-2642
-
-
Minaguchi, T.1
Yoshikawa, H.2
Oda, K.3
-
5
-
-
0038615946
-
Analysis of the phosphatidylinositol 3′-kinase signaling pathway in glioblastoma patients in vivo
-
Choe G, Horvath S, Cloughesy TF, et al. Analysis of the phosphatidylinositol 3′-kinase signaling pathway in glioblastoma patients in vivo. Cancer Res 2003;63:2742-6.
-
(2003)
Cancer Res
, vol.63
, pp. 2742-2746
-
-
Choe, G.1
Horvath, S.2
Cloughesy, T.F.3
-
6
-
-
0032590011
-
PIK3CA is implicated as an oncogene in ovarian cancer
-
Shayesteh L, Lu Y, Kuo WL, et al. PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet 1999;21:99-102.
-
(1999)
Nat Genet
, vol.21
, pp. 99-102
-
-
Shayesteh, L.1
Lu, Y.2
Kuo, W.L.3
-
7
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
Samuels Y, Wang Z, Bardelli A, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004;304:554.
-
(2004)
Science
, vol.304
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
-
8
-
-
14144252004
-
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic
-
Kang S, Bader AG, Vogt PK. Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. Proc Natl Acad Sci U S A 2005;102:802-7.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 802-807
-
-
Kang, S.1
Bader, A.G.2
Vogt, P.K.3
-
9
-
-
3442878125
-
Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas
-
Broderick DK, Di C, Parrett TJ, et al. Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas. Cancer Res 2004;64:5048-50.
-
(2004)
Cancer Res
, vol.64
, pp. 5048-5050
-
-
Broderick, D.K.1
Di, C.2
Parrett, T.J.3
-
10
-
-
20144387695
-
PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma
-
Saal LH, Holm K, Maurer M, et al. PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. Cancer Res 2005;65:2554-9.
-
(2005)
Cancer Res
, vol.65
, pp. 2554-2559
-
-
Saal, L.H.1
Holm, K.2
Maurer, M.3
-
11
-
-
0035179871
-
Assembly of microarrays for genome-wide measurement of DNA copy number
-
Snijders AM, Nowak N, Segraves R, et al. Assembly of microarrays for genome-wide measurement of DNA copy number. Nat Genet 2001;29:263-4.
-
(2001)
Nat Genet
, vol.29
, pp. 263-264
-
-
Snijders, A.M.1
Nowak, N.2
Segraves, R.3
-
12
-
-
7444250290
-
Mutation of the PIK3CA gene in ovarian and breast cancer
-
Campbell IG, Russell SE, Choong DY, et al. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res 2004;64:7678-81.
-
(2004)
Cancer Res
, vol.64
, pp. 7678-7681
-
-
Campbell, I.G.1
Russell, S.E.2
Choong, D.Y.3
-
13
-
-
20044388328
-
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas
-
Lee JW, Soung YH, Kim SY, et al. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 2005;24:1477-80.
-
(2005)
Oncogene
, vol.24
, pp. 1477-1480
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
-
14
-
-
0027988421
-
Analysis of clonality by amplification of short tandem repeats. Carcinomas of the female reproductive tract
-
Enomoto T, Fujita M, Inoue M, Tanizawa O, Nomura T, Shroyer KR. Analysis of clonality by amplification of short tandem repeats. Carcinomas of the female reproductive tract. Diagn Mol Pathol 1994;3:292-7.
-
(1994)
Diagn Mol Pathol
, vol.3
, pp. 292-297
-
-
Enomoto, T.1
Fujita, M.2
Inoue, M.3
Tanizawa, O.4
Nomura, T.5
Shroyer, K.R.6
-
15
-
-
1242284600
-
Regulation of cell migration by the C2 domain of the tumor suppressor PTEN
-
Raftopoulou M, Etienne Manneville S, Self A, Nicholls A, Hall A. Regulation of cell migration by the C2 domain of the tumor suppressor PTEN. Science 2004;303:1179-81.
-
(2004)
Science
, vol.303
, pp. 1179-1181
-
-
Raftopoulou, M.1
Etienne Manneville, S.2
Self, A.3
Nicholls, A.4
Hall, A.5
-
16
-
-
0041450058
-
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms
-
Freeman DJ, Li AG, Wei CT, et al. PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms. Cancer Cell 2003;3:117-30.
-
(2003)
Cancer Cell
, vol.3
, pp. 117-130
-
-
Freeman, D.J.1
Li, A.G.2
Wei, C.T.3
-
17
-
-
14544282456
-
Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor
-
Okumura K, Zhao M, Depinho RA, Furnari FB, Cavenee WK. Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor. Proc Natl Acad Sci U S A 2005;102:2703-6.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 2703-2706
-
-
Okumura, K.1
Zhao, M.2
Depinho, R.A.3
Furnari, F.B.4
Cavenee, W.K.5
-
18
-
-
0035190026
-
Cellular function of phosphoinositide 3-kinases: Implications for development, homeostasis, and cancer
-
Katso R, Okkenhaug K, Ahmadi K, White S, Timms J, Waterfield MD. Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer. Annu Rev Cell Dev Biol 2001;17:615-75.
-
(2001)
Annu Rev Cell Dev Biol
, vol.17
, pp. 615-675
-
-
Katso, R.1
Okkenhaug, K.2
Ahmadi, K.3
White, S.4
Timms, J.5
Waterfield, M.D.6
-
19
-
-
20444374445
-
Mutant PIK3CA promotes cell growth and invasion of human cancer cells
-
Samuels Y, Diaz LA, Jr., Schmidt Kittler O, et al. Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Cancer Cell 2005;7:561-73.
-
(2005)
Cancer Cell
, vol.7
, pp. 561-573
-
-
Samuels, Y.1
Diaz Jr., L.A.2
Schmidt Kittler, O.3
-
20
-
-
2542619821
-
Genomic aberrations in carcinomas of the uterine corpus
-
Micci F, Tebteira MR, Haugom L, Kristensen G, Abeler VM, Heim S. Genomic aberrations in carcinomas of the uterine corpus. Genes Chromosomes Cancer 2004;40:229-46.
-
(2004)
Genes Chromosomes Cancer
, vol.40
, pp. 229-246
-
-
Micci, F.1
Tebteira, M.R.2
Haugom, L.3
Kristensen, G.4
Abeler, V.M.5
Heim, S.6
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