Identification of potential genomic biomarkers of hepatotoxicity caused by reactive metabolites of N-methylformamide: Application of stable isotope labeled compounds in toxicogenomic studies

Chemical Research in Toxicology

Volumn 19, Issue 10, 2006, Pages 1270-1283

  Mutlib, Abdul ^a   Jiang, Ping ^a   Atherton, Jim ^a   Obert, Leslie ^a   Kostrubsky, Seva ^a   Madore, Steven ^a   Nelson, Sidney ^b  

^a PFIZER INC   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; DEUTERIUM; METHYL ISOCYANATE; N METHYLFORMAMIDE; STABLE ISOTOPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD CHEMISTRY; CELL CYCLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DATA BASE; DEVICE; GENE EXPRESSION; GENOMICS; HISTOPATHOLOGY; ISOTOPE LABELING; LIVER METABOLISM; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA TRANSCRIPTION; STATISTICAL SIGNIFICANCE;

ANIMALS; BIOLOGICAL MARKERS; DOWN-REGULATION; FORMAMIDES; GENOME; ISOTOPE LABELING; KINETICS; LIVER; MALE; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; TIME FACTORS; TOXICOGENETICS; UP-REGULATION;

ANIMALIA;

EID: 33750213132     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx060093j     Document Type: Article

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