메뉴 건너뛰기




Volumn 20, Issue 10, 2006, Pages 2265-2277

Androgen activation of the sterol regulatory element-binding protein pathway: Current insights

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; GROWTH FACTOR; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR;

EID: 33749356751     PISSN: 08888809     EISSN: 08888809     Source Type: Journal    
DOI: 10.1210/me.2005-0479     Document Type: Short Survey
Times cited : (113)

References (100)
  • 1
    • 0022931034 scopus 로고
    • Hormonal control of sexual development
    • George FW, Wilson JD 1986 Hormonal control of sexual development. Vitam Horm 43:145-196
    • (1986) Vitam Horm , vol.43 , pp. 145-196
    • George, F.W.1    Wilson, J.D.2
  • 3
    • 84984385774 scopus 로고
    • Permanent effects of foetal and neonatal testosterone secretion on steroid metabolism and binding
    • De Moor P, Verhoeven G, Heyns W 1973 Permanent effects of foetal and neonatal testosterone secretion on steroid metabolism and binding. Differentiation 1:241-253
    • (1973) Differentiation , vol.1 , pp. 241-253
    • De Moor, P.1    Verhoeven, G.2    Heyns, W.3
  • 4
    • 0028283503 scopus 로고
    • Molecular mechanisms of action of steroid/thyroid receptor superfamily members
    • Tsai MJ, O'Malley BW 1994 Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem 63:451-486
    • (1994) Annu Rev Biochem , vol.63 , pp. 451-486
    • Tsai, M.J.1    O'Malley, B.W.2
  • 5
    • 0030790495 scopus 로고    scopus 로고
    • Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF
    • McEwan IJ, Gustafsson J 1997 Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF. Proc Natl Acad Sci USA 94:8485-8490
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8485-8490
    • McEwan, I.J.1    Gustafsson, J.2
  • 6
    • 0004080381 scopus 로고    scopus 로고
    • From androgen receptor to the general transcription factor TFIIH. Identification of cdk activating kinase (CAK) as an androgen receptor NH(2)-terminal associated coactivator
    • Lee DK, Duan HO, Chang C 2000 From androgen receptor to the general transcription factor TFIIH. Identification of cdk activating kinase (CAK) as an androgen receptor NH(2)-terminal associated coactivator. J Biol Chem 275:9308-9313
    • (2000) J Biol Chem , vol.275 , pp. 9308-9313
    • Lee, D.K.1    Duan, H.O.2    Chang, C.3
  • 7
    • 0037229956 scopus 로고    scopus 로고
    • Molecular communication between androgen receptor and general transcription machinery
    • Lee DK, Chang C 2003 Molecular communication between androgen receptor and general transcription machinery. J Steroid Biochem Mol Biol 84:41-49
    • (2003) J Steroid Biochem Mol Biol , vol.84 , pp. 41-49
    • Lee, D.K.1    Chang, C.2
  • 8
    • 0036219918 scopus 로고    scopus 로고
    • Androgen receptor (AR) coregulators: An overview
    • Heinlein CA, Chang C 2002 Androgen receptor (AR) coregulators: an overview. Endocr Rev 23:175-200
    • (2002) Endocr Rev , vol.23 , pp. 175-200
    • Heinlein, C.A.1    Chang, C.2
  • 9
    • 2342558431 scopus 로고    scopus 로고
    • Androgen receptor in prostate cancer
    • Heinlein CA, Chang C 2004 Androgen receptor in prostate cancer. Endocr Rev 25:276-308
    • (2004) Endocr Rev , vol.25 , pp. 276-308
    • Heinlein, C.A.1    Chang, C.2
  • 10
    • 17144432214 scopus 로고    scopus 로고
    • Androgen receptor corepressors: An overview
    • Wang L, Hsu CL, Chang C 2005 Androgen receptor corepressors: an overview. Prostate 63:117-130
    • (2005) Prostate , vol.63 , pp. 117-130
    • Wang, L.1    Hsu, C.L.2    Chang, C.3
  • 11
    • 0033602857 scopus 로고    scopus 로고
    • Indirect mechanisms and cascades of androgen action
    • Verhoeven G, Swinnen JV 1999 Indirect mechanisms and cascades of androgen action. Mol Cell Endocrinol 151:205-212
    • (1999) Mol Cell Endocrinol , vol.151 , pp. 205-212
    • Verhoeven, G.1    Swinnen, J.V.2
  • 12
    • 0030666828 scopus 로고    scopus 로고
    • Coordinate regulation of lipogenic gene expression by androgens: Evidence for a cascade mechanism involving sterol regulatory element binding proteins
    • Swinnen JV, Ulrix W, Heyns W, Verhoeven G 1997 Coordinate regulation of lipogenic gene expression by androgens: evidence for a cascade mechanism involving sterol regulatory element binding proteins. Proc Natl Acad Sci USA 94:12975-12980
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12975-12980
    • Swinnen, J.V.1    Ulrix, W.2    Heyns, W.3    Verhoeven, G.4
  • 13
    • 0027190308 scopus 로고
    • Nuclear protein that binds to sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence
    • Briggs MR, Yokoyama C, Wang X, Brown MS, Goldstein JL 1993 Nuclear protein that binds to sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence. J Biol Chem 268:14490-14496
    • (1993) J Biol Chem , vol.268 , pp. 14490-14496
    • Briggs, M.R.1    Yokoyama, C.2    Wang, X.3    Brown, M.S.4    Goldstein, J.L.5
  • 14
    • 0027167918 scopus 로고
    • Nuclear protein that binds sterol regulatory element of the low density lipoprotein receptor promoter. II. Purification and characterisation
    • Wang X, Briggs MR, Hua X, Yokoyama C, Goldstein JL, Brown MS 1993 Nuclear protein that binds sterol regulatory element of the low density lipoprotein receptor promoter. II. Purification and characterisation. J Biol Chem 268:14497-14504
    • (1993) J Biol Chem , vol.268 , pp. 14497-14504
    • Wang, X.1    Briggs, M.R.2    Hua, X.3    Yokoyama, C.4    Goldstein, J.L.5    Brown, M.S.6
  • 15
    • 0027648820 scopus 로고
    • ADD1: A novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation
    • Tontonoz P, Kim JB, Graves RA, Spiegelman BM 1993 ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation. Mol Cell Biol 13:4753-4759
    • (1993) Mol Cell Biol , vol.13 , pp. 4753-4759
    • Tontonoz, P.1    Kim, J.B.2    Graves, R.A.3    Spiegelman, B.M.4
  • 16
    • 0027490174 scopus 로고
    • SREBP-1, a basic helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
    • Yokoyama C, Wang X, Briggs MR, Admon A, Wu J, Hua X, Goldstein JL, Brown MS 1993 SREBP-1, a basic helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell 75:187-197
    • (1993) Cell , vol.75 , pp. 187-197
    • Yokoyama, C.1    Wang, X.2    Briggs, M.R.3    Admon, A.4    Wu, J.5    Hua, X.6    Goldstein, J.L.7    Brown, M.S.8
  • 17
    • 0028960739 scopus 로고
    • Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF-1) and localisation of SREBF-1 and SREBF-2 to chromosomes 17p11.2 and 22q13
    • Hua X, Wu J, Goldstein JL, Brown MS, Hobbs HH 1995 Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF-1) and localisation of SREBF-1 and SREBF-2 to chromosomes 17p11.2 and 22q13. Genomics 25:667-673
    • (1995) Genomics , vol.25 , pp. 667-673
    • Hua, X.1    Wu, J.2    Goldstein, J.L.3    Brown, M.S.4    Hobbs, H.H.5
  • 18
    • 0027139362 scopus 로고
    • SREBP-2, a second basic helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element
    • Hua X, Yokoyama C, Wu J, Briggs MR, Brown MS, Goldstein JL, Wang X 1993 SREBP-2, a second basic helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element. Proc Natl Acad Sci USA 90:11603-11607
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11603-11607
    • Hua, X.1    Yokoyama, C.2    Wu, J.3    Briggs, M.R.4    Brown, M.S.5    Goldstein, J.L.6    Wang, X.7
  • 19
    • 0031568872 scopus 로고    scopus 로고
    • Structure of the human gene encoding sterol regulatory element binding protein 2 (SREBF-2)
    • Miserez AR, Cao G, Probst LC, Hobbs HH 1997 Structure of the human gene encoding sterol regulatory element binding protein 2 (SREBF-2). Genomics 40:31-40
    • (1997) Genomics , vol.40 , pp. 31-40
    • Miserez, A.R.1    Cao, G.2    Probst, L.C.3    Hobbs, H.H.4
  • 20
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown MS, Goldstein JL 1997 The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89:331-340
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 21
    • 0036893268 scopus 로고    scopus 로고
    • Expression of a novel, sterol-insensitive form of sterol regulatory element binding protein 2 (SREBP2) in male germ cells suggests important cell- and stage-specific functions for SREBP targets during spermatogenesis
    • Wang H, Liu F, Millette CF, Kilpatrick DL 2002 Expression of a novel, sterol-insensitive form of sterol regulatory element binding protein 2 (SREBP2) in male germ cells suggests important cell- and stage-specific functions for SREBP targets during spermatogenesis. Mol Cell Biol 24:8478-8490
    • (2002) Mol Cell Biol , vol.24 , pp. 8478-8490
    • Wang, H.1    Liu, F.2    Millette, C.F.3    Kilpatrick, D.L.4
  • 22
    • 10044250112 scopus 로고    scopus 로고
    • Novel role for a sterol response element binding protein in directing spermatogenic cell-specific gene expression
    • Wang H, San Agustin JT, Witman GB, Kilpatrick DL 2004 Novel role for a sterol response element binding protein in directing spermatogenic cell-specific gene expression. Mol Cell Biol 24:10681-10688
    • (2004) Mol Cell Biol , vol.24 , pp. 10681-10688
    • Wang, H.1    San Agustin, J.T.2    Witman, G.B.3    Kilpatrick, D.L.4
  • 23
    • 0030854859 scopus 로고    scopus 로고
    • Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein
    • Sakai J, Nohturfft A, Cheng D, Ho YK, Brown MS, Goldstein JL 1997 Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein. J Biol Chem 272:20213-20221
    • (1997) J Biol Chem , vol.272 , pp. 20213-20221
    • Sakai, J.1    Nohturfft, A.2    Cheng, D.3    Ho, Y.K.4    Brown, M.S.5    Goldstein, J.L.6
  • 24
    • 0034703033 scopus 로고    scopus 로고
    • Overexpression of membrane domain of SCAP prevents from inhibiting SCAP-SREBP exit from endoplasmic reticulum
    • Yang T, Goldstein JL, Brown MS 2000 Overexpression of membrane domain of SCAP prevents from inhibiting SCAP-SREBP exit from endoplasmic reticulum. J Biol Chem 275:29881-29886
    • (2000) J Biol Chem , vol.275 , pp. 29881-29886
    • Yang, T.1    Goldstein, J.L.2    Brown, M.S.3
  • 25
    • 0037162719 scopus 로고    scopus 로고
    • Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
    • Yang T, Espenshade PJ, Wright ME, Yabe D, Gong Y, Aebersold R, Goldstein JL, Brown MS 2002 Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell 110:489-500
    • (2002) Cell , vol.110 , pp. 489-500
    • Yang, T.1    Espenshade, P.J.2    Wright, M.E.3    Yabe, D.4    Gong, Y.5    Aebersold, R.6    Goldstein, J.L.7    Brown, M.S.8
  • 26
    • 0036792050 scopus 로고    scopus 로고
    • Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins
    • Yabe D, Brown MS, Goldstein JL 2002 Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins. Proc Natl Acad Sci USA 99:12753-12758
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12753-12758
    • Yabe, D.1    Brown, M.S.2    Goldstein, J.L.3
  • 27
    • 0033613126 scopus 로고    scopus 로고
    • Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi
    • Nohturfft A, DeBose-Boyd RA, Scheek S, Goldstein JL, Brown MS 1999 Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi. Proc Natl Acad Sci USA 96:11235-11240
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11235-11240
    • Nohturfft, A.1    DeBose-Boyd, R.A.2    Scheek, S.3    Goldstein, J.L.4    Brown, M.S.5
  • 28
    • 5644244825 scopus 로고    scopus 로고
    • Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl- coenzyme A reductase
    • Sever N, Lee PCW, Song B-L, Rawson RB, DeBose-Boyd RA 2004 Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Biol Chem 279:43136-43147
    • (2004) J Biol Chem , vol.279 , pp. 43136-43147
    • Sever, N.1    Lee, P.C.W.2    Song, B.-L.3    Rawson, R.B.4    DeBose-Boyd, R.A.5
  • 29
    • 0032185770 scopus 로고    scopus 로고
    • Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells
    • Sakai J, Rawson RB, Espenshade PJ, Cheng D, Seegmiller AC, Goldstein JL, Brown MS 1999 Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells. Mol Cell 2:505-514
    • (1999) Mol Cell , vol.2 , pp. 505-514
    • Sakai, J.1    Rawson, R.B.2    Espenshade, P.J.3    Cheng, D.4    Seegmiller, A.C.5    Goldstein, J.L.6    Brown, M.S.7
  • 31
    • 0034681260 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans
    • Brown MS, Ye J, Rawson RB, Goldstein JL 2000 Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell 100:391-398
    • (2000) Cell , vol.100 , pp. 391-398
    • Brown, M.S.1    Ye, J.2    Rawson, R.B.3    Goldstein, J.L.4
  • 32
    • 0029797604 scopus 로고    scopus 로고
    • Overproduction of cholesterol and fatty acids cause massive liver enlargement in transgenic mice expressing truncated SREBP-1a
    • Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL 1996 Overproduction of cholesterol and fatty acids cause massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J Clin Invest 98:1575-1584
    • (1996) J Clin Invest , vol.98 , pp. 1575-1584
    • Shimano, H.1    Horton, J.D.2    Hammer, R.E.3    Shimomura, I.4    Brown, M.S.5    Goldstein, J.L.6
  • 33
    • 0030907175 scopus 로고    scopus 로고
    • Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
    • Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, Goldstein JL 1997 Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J Clin Invest 99:846-854
    • (1997) J Clin Invest , vol.99 , pp. 846-854
    • Shimano, H.1    Horton, J.D.2    Shimomura, I.3    Hammer, R.E.4    Brown, M.S.5    Goldstein, J.L.6
  • 34
    • 0032104180 scopus 로고    scopus 로고
    • Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element binding protein-2
    • Horton JD, Shimomura I, Brown Ms, Hammer RE, Goldstein JL, Shimano H 1998 Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element binding protein-2. J Clin Invest 101:2331-2339
    • (1998) J Clin Invest , vol.101 , pp. 2331-2339
    • Horton, J.D.1    Shimomura, I.2    Brown, Ms.3    Hammer, R.E.4    Goldstein, J.L.5    Shimano, H.6
  • 36
    • 0028978248 scopus 로고
    • Purification of an interleukin-1β converting enzyme related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains
    • Wang X, Pai J-T, Wiedenfeld EA, Medina JC, Slaughter CA, Goldstein JL, Brown MS 1995 Purification of an interleukin-1β converting enzyme related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains. J Biol Chem 270:18044-18050
    • (1995) J Biol Chem , vol.270 , pp. 18044-18050
    • Wang, X.1    Pai, J.-T.2    Wiedenfeld, E.A.3    Medina, J.C.4    Slaughter, C.A.5    Goldstein, J.L.6    Brown, M.S.7
  • 37
    • 0029895343 scopus 로고    scopus 로고
    • Purification and cDNA cloning of a second apoptosis related cysteine protease that cleaves and activates sterol regulatory element binding proteins
    • Pai J-T, Brown MS, Goldstein JL 1996 Purification and cDNA cloning of a second apoptosis related cysteine protease that cleaves and activates sterol regulatory element binding proteins. Proc Natl Acad Sci USA 93:5437-5442
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5437-5442
    • Pai, J.-T.1    Brown, M.S.2    Goldstein, J.L.3
  • 38
    • 0035667902 scopus 로고    scopus 로고
    • Apoptosis-induced release of mature sterol regulatory element-binding proteins activates sterol-responsive genes
    • Higgins ME, Ioannou YA 2001 Apoptosis-induced release of mature sterol regulatory element-binding proteins activates sterol-responsive genes. J Lipid Res 42:1939-1946
    • (2001) J Lipid Res , vol.42 , pp. 1939-1946
    • Higgins, M.E.1    Ioannou, Y.A.2
  • 39
    • 0029958652 scopus 로고    scopus 로고
    • Sterol-dependent transcriptional regulation of sterol-regulatory element-binding protein-2
    • Sato R, Inoue J, Kawabe Y, Komada T, Tokano T, Maeda M 1996 Sterol-dependent transcriptional regulation of sterol-regulatory element-binding protein-2. J Biol Chem 271:26461-26464
    • (1996) J Biol Chem , vol.271 , pp. 26461-26464
    • Sato, R.1    Inoue, J.2    Kawabe, Y.3    Komada, T.4    Tokano, T.5    Maeda, M.6
  • 43
    • 0034235363 scopus 로고    scopus 로고
    • Regulation of sterol regulatory-element binding protein 1 gene expression in liver: Role of insulin and protein kinase B/cAkt
    • Fleischmann M, Iynedjsan PB 2000 Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt. Biochem J 349:13-17
    • (2000) Biochem J , vol.349 , pp. 13-17
    • Fleischmann, M.1    Iynedjsan, P.B.2
  • 44
    • 0036096106 scopus 로고    scopus 로고
    • Estrogen activates the high-density lipoprotein receptor gene via binding to estrogen response elements and interaction with sterol regulatory element binding protein-1A
    • Lopez D, Sanchez MD, Shea-Eaton W, McLean MP 2002 Estrogen activates the high-density lipoprotein receptor gene via binding to estrogen response elements and interaction with sterol regulatory element binding protein-1A. Endocrinology 143:2155-2168
    • (2002) Endocrinology , vol.143 , pp. 2155-2168
    • Lopez, D.1    Sanchez, M.D.2    Shea-Eaton, W.3    McLean, M.P.4
  • 45
    • 0037205445 scopus 로고    scopus 로고
    • Sterol regulatory element-binding protein-1 interacts with the nuclear thyroid hormone receptor to enhance acetyl-CoA carboxylase-α transcription in hepatocytes
    • Yin L, Zhang Y, Hillgartner FB 2002 Sterol regulatory element-binding protein-1 interacts with the nuclear thyroid hormone receptor to enhance acetyl-CoA carboxylase-α transcription in hepatocytes. J Biol Chem 277:19554-19565
    • (2002) J Biol Chem , vol.277 , pp. 19554-19565
    • Yin, L.1    Zhang, Y.2    Hillgartner, F.B.3
  • 48
    • 0034721772 scopus 로고    scopus 로고
    • MAP kinase Erk 1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro
    • Roth G, Kotzka J, Kremer L, Lehr S, Lohaus C, Meyer HE, Krone W, Muller-Wieland D 2000 MAP kinase Erk 1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro. J Biol Chem 275:33302-33307
    • (2000) J Biol Chem , vol.275 , pp. 33302-33307
    • Roth, G.1    Kotzka, J.2    Kremer, L.3    Lehr, S.4    Lohaus, C.5    Meyer, H.E.6    Krone, W.7    Muller-Wieland, D.8
  • 49
    • 0035830840 scopus 로고    scopus 로고
    • Unsaturated fatty acids down-regulate SREBP isoforms 1a and 1c by two mechanisms in HEK-293 cells
    • Hannah VC, Ou J, Luong A, Goldstein JL, Brown MS 2001 Unsaturated fatty acids down-regulate SREBP isoforms 1a and 1c by two mechanisms in HEK-293 cells. J Biol Chem 276:4365-4372
    • (2001) J Biol Chem , vol.276 , pp. 4365-4372
    • Hannah, V.C.1    Ou, J.2    Luong, A.3    Goldstein, J.L.4    Brown, M.S.5
  • 50
    • 0027964818 scopus 로고
    • Androgen regulation of the messenger RNA encoding diazepam-binding inhibitor/acyl-CoA-binding protein in the human prostatic adenomacarcinoma cell line LNCaP
    • Swinnen JV, Esquenet M, Heyns W, Rombauts W, Verhoeven G 1994 Androgen regulation of the messenger RNA encoding diazepam-binding inhibitor/acyl-CoA- binding protein in the human prostatic adenomacarcinoma cell line LNCaP. Mol Cell Endocrinol 104:153-162
    • (1994) Mol Cell Endocrinol , vol.104 , pp. 153-162
    • Swinnen, J.V.1    Esquenet, M.2    Heyns, W.3    Rombauts, W.4    Verhoeven, G.5
  • 51
    • 0029877565 scopus 로고    scopus 로고
    • A human gene encoding diazepam-binding inhibitor/acyl-CoA-binding protein: Transcription and hormonal regulation in the androgen-sensitive human prostatic adenocarcinoma cell line LNCaP
    • Swinnen JV, Esquenet M, Rosseels J, Claessens F, Rombauts W, Heyns W, Verhoeven G 1996 A human gene encoding diazepam-binding inhibitor/acyl-CoA- binding protein: transcription and hormonal regulation in the androgen-sensitive human prostatic adenocarcinoma cell line LNCaP. DNA Cell Biol 15:197-208
    • (1996) DNA Cell Biol , vol.15 , pp. 197-208
    • Swinnen, J.V.1    Esquenet, M.2    Rosseels, J.3    Claessens, F.4    Rombauts, W.5    Heyns, W.6    Verhoeven, G.7
  • 52
    • 0029743674 scopus 로고    scopus 로고
    • Androgens markedly stimulate the accumulation of neutral lipids in the human prostatic adenocarcinoma cell line LNCaP
    • Swinnen JV, Van Veldhoven PP, Esquenet M, Heyns W, Verhoeven G 1996 Androgens markedly stimulate the accumulation of neutral lipids in the human prostatic adenocarcinoma cell line LNCaP. Endocrinology 137:4468-4474
    • (1996) Endocrinology , vol.137 , pp. 4468-4474
    • Swinnen, J.V.1    Van Veldhoven, P.P.2    Esquenet, M.3    Heyns, W.4    Verhoeven, G.5
  • 53
    • 0030936232 scopus 로고    scopus 로고
    • Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP
    • Swinnen JV, Esquenet M, Goossens K, Heyns W, Verhoeven G 1997 Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP. Cancer Res 57:1086-1090
    • (1997) Cancer Res , vol.57 , pp. 1086-1090
    • Swinnen, J.V.1    Esquenet, M.2    Goossens, K.3    Heyns, W.4    Verhoeven, G.5
  • 54
    • 0032493636 scopus 로고    scopus 로고
    • Identification of diazepam-binding inhibitor/acyl-CoA-binding protein as a sterol regulatory element-binding protein responsive gene
    • Swinnen JV, Alen P, Heyns W, Verhoeven G 1998 Identification of diazepam-binding inhibitor/acyl-CoA-binding protein as a sterol regulatory element-binding protein responsive gene. J Biol Chem 273:19938-19944
    • (1998) J Biol Chem , vol.273 , pp. 19938-19944
    • Swinnen, J.V.1    Alen, P.2    Heyns, W.3    Verhoeven, G.4
  • 55
    • 0034791515 scopus 로고    scopus 로고
    • Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway
    • Heemers H, Maes B, Foufelle F, Heyns W, Verhoeven G, Swinnen JV 2001 Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway. Mol Endocrinol 15:1817-1828
    • (2001) Mol Endocrinol , vol.15 , pp. 1817-1828
    • Heemers, H.1    Maes, B.2    Foufelle, F.3    Heyns, W.4    Verhoeven, G.5    Swinnen, J.V.6
  • 56
    • 33749322878 scopus 로고    scopus 로고
    • Androgens stimulate the SREBP pathway in prostate cancer cells by inducing a shift in the SCAP-retention protein(s) balance
    • Li JJ, Li SA, Llombart-Bosch A, eds. New York: Springer
    • Heemers H, Heyns W, Verhoeven G, Swinnen JV 2005 Androgens stimulate the SREBP pathway in prostate cancer cells by inducing a shift in the SCAP-retention protein(s) balance. In: Li JJ, Li SA, Llombart-Bosch A, eds. Hormonal carcinogenesis. 1st ed. New York: Springer; 357-363
    • (2005) Hormonal Carcinogenesis. 1st Ed. , pp. 357-363
    • Heemers, H.1    Heyns, W.2    Verhoeven, G.3    Swinnen, J.V.4
  • 57
    • 0032722483 scopus 로고    scopus 로고
    • Genomic structure and chromosomal mapping of the human sterol regulatory element binding protein (SREBP) cleavage-activating protein (SCAP) gene
    • Nakajima T, Hamakubo T, Kodama T, Inazama J, Emi M 1999 Genomic structure and chromosomal mapping of the human sterol regulatory element binding protein (SREBP) cleavage-activating protein (SCAP) gene. J Hum Genet 44:402-407
    • (1999) J Hum Genet , vol.44 , pp. 402-407
    • Nakajima, T.1    Hamakubo, T.2    Kodama, T.3    Inazama, J.4    Emi, M.5
  • 58
    • 3142739478 scopus 로고    scopus 로고
    • Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor
    • Heemers H, Verrijdt G, Organe S, Claessens F, Heyns W, Verhoeven G, Swinnen JV 2004 Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor. J Biol Chem 279:30880-30887
    • (2004) J Biol Chem , vol.279 , pp. 30880-30887
    • Heemers, H.1    Verrijdt, G.2    Organe, S.3    Claessens, F.4    Heyns, W.5    Verhoeven, G.6    Swinnen, J.V.7
  • 59
    • 0037340162 scopus 로고    scopus 로고
    • Selective DNA recognition by the androgen receptor as a mechanism for hormone-specific regulation of gene expression
    • Verrijdt G, Haelens A, Claessens F 2003 Selective DNA recognition by the androgen receptor as a mechanism for hormone-specific regulation of gene expression. Mol Genet Metab 78:175-185
    • (2003) Mol Genet Metab , vol.78 , pp. 175-185
    • Verrijdt, G.1    Haelens, A.2    Claessens, F.3
  • 60
    • 0024417508 scopus 로고
    • Functional characterization of an androgen response element in the first intron of the C3(1) gene of prostatic binding protein
    • Claessens F, Celis L, Peeters B, Heyns W, Verhoeven G, Rombauts W 1989 Functional characterization of an androgen response element in the first intron of the C3(1) gene of prostatic binding protein. Biochem Biophys Res Commun 164:833-840
    • (1989) Biochem Biophys Res Commun , vol.164 , pp. 833-840
    • Claessens, F.1    Celis, L.2    Peeters, B.3    Heyns, W.4    Verhoeven, G.5    Rombauts, W.6
  • 62
    • 0025986845 scopus 로고
    • Androgen responsiveness of the murine β-glucuronidase gene is associated with nuclease hypersensitivity, protein binding, and haplotype-specific sequence diversity within intron 9
    • Lund SD, Gallagher PM, Wang B, Porter SC, Ganschow RE 1991 Androgen responsiveness of the murine β-glucuronidase gene is associated with nuclease hypersensitivity, protein binding, and haplotype-specific sequence diversity within intron 9. Mol Cell Biol 11:5426-5434
    • (1991) Mol Cell Biol , vol.11 , pp. 5426-5434
    • Lund, S.D.1    Gallagher, P.M.2    Wang, B.3    Porter, S.C.4    Ganschow, R.E.5
  • 64
    • 0037453007 scopus 로고    scopus 로고
    • Liver-specific mRNA for Insig-2 down-regulated by insulin: Implications for fatty acid synthesis
    • Yabe D, Komuro R, Liang G, Goldstein JL, Brown MS 2003 Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis. Proc Natl Acad Sci USA 100:3155-3160
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 3155-3160
    • Yabe, D.1    Komuro, R.2    Liang, G.3    Goldstein, J.L.4    Brown, M.S.5
  • 65
    • 2142751644 scopus 로고    scopus 로고
    • Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis
    • Engelking LJ, Kuriyama H, Hammer RE, Horton JD, Brown MS, Goldstein JL, Liang G 2004 Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis. J Clin Invest 113:1168-1175
    • (2004) J Clin Invest , vol.113 , pp. 1168-1175
    • Engelking, L.J.1    Kuriyama, H.2    Hammer, R.E.3    Horton, J.D.4    Brown, M.S.5    Goldstein, J.L.6    Liang, G.7
  • 68
    • 0041566862 scopus 로고    scopus 로고
    • Gene expression changes following androgen receptor elimination in LNCaP prostate cancer cells
    • Eder IE, Haag P, Basik M, Mousses S, Bektic J, Bartsch G, Klocker H 2003 Gene expression changes following androgen receptor elimination in LNCaP prostate cancer cells. Mol Carcinog 37:181-191
    • (2003) Mol Carcinog , vol.37 , pp. 181-191
    • Eder, I.E.1    Haag, P.2    Basik, M.3    Mousses, S.4    Bektic, J.5    Bartsch, G.6    Klocker, H.7
  • 70
    • 0032743557 scopus 로고    scopus 로고
    • Two mutations identified in the androgen receptor of the new human prostate cancer cell line MDA PCa 2a
    • Zhao XY, Boyle B, Krishnan AV, Navone NM, Peehl DM, Feldman D 1999 Two mutations identified in the androgen receptor of the new human prostate cancer cell line MDA PCa 2a. J Urol 162:2192-2199
    • (1999) J Urol , vol.162 , pp. 2192-2199
    • Zhao, X.Y.1    Boyle, B.2    Krishnan, A.V.3    Navone, N.M.4    Peehl, D.M.5    Feldman, D.6
  • 75
    • 0035131412 scopus 로고    scopus 로고
    • Fatty acid synthase: An early molecular marker of progression of prostatic adenocarcinoma to androgen independence
    • Myers RB, Oelschlager DK, Weiss HL, Frost AR, Grizzle WE 2001 Fatty acid synthase: an early molecular marker of progression of prostatic adenocarcinoma to androgen independence. J Urol 165:1027-1032
    • (2001) J Urol , vol.165 , pp. 1027-1032
    • Myers, R.B.1    Oelschlager, D.K.2    Weiss, H.L.3    Frost, A.R.4    Grizzle, W.E.5
  • 76
    • 1542615071 scopus 로고    scopus 로고
    • Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence
    • Ettinger SL, Sobel R, Whitmore TG, Akbari M, Bradley DR, Gleave ME, Nelson CC 2004 Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence. Cancer Res 64:2212-2221
    • (2004) Cancer Res , vol.64 , pp. 2212-2221
    • Ettinger, S.L.1    Sobel, R.2    Whitmore, T.G.3    Akbari, M.4    Bradley, D.R.5    Gleave, M.E.6    Nelson, C.C.7
  • 78
    • 0034718771 scopus 로고    scopus 로고
    • Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway
    • Swinnen JV, Heemers H, Deboel L, Foufelle F, Heyns W, Verhoeven G 2000 Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway. Oncogene 19:5173-5181
    • (2000) Oncogene , vol.19 , pp. 5173-5181
    • Swinnen, J.V.1    Heemers, H.2    Deboel, L.3    Foufelle, F.4    Heyns, W.5    Verhoeven, G.6
  • 79
    • 0034749615 scopus 로고    scopus 로고
    • Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state
    • Murillo H, Huang H, Schmidt LJ, Smith DI, Tindall DJ 2001 Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state. Endocrinology 142:4795-4805
    • (2001) Endocrinology , vol.142 , pp. 4795-4805
    • Murillo, H.1    Huang, H.2    Schmidt, L.J.3    Smith, D.I.4    Tindall, D.J.5
  • 81
    • 0029867610 scopus 로고    scopus 로고
    • Androgen regulation of the messenger RNA encoding diazepam-binding inhibitor/acyl-CoA-binding protein in the rat
    • Swinnen JV, Vercaeren I, Esquenet M, Heyns W, Verhoeven G 1996 Androgen regulation of the messenger RNA encoding diazepam-binding inhibitor/acyl-CoA- binding protein in the rat. Mol Cell Endocrinol 118:65-70
    • (1996) Mol Cell Endocrinol , vol.118 , pp. 65-70
    • Swinnen, J.V.1    Vercaeren, I.2    Esquenet, M.3    Heyns, W.4    Verhoeven, G.5
  • 83
    • 0037387184 scopus 로고    scopus 로고
    • Identification of androgen-responsive genes in the rat ventral prostate by complementary deoxyribonucleic acid subtraction and microarray
    • Jiang F, Wang Z 2003 Identification of androgen-responsive genes in the rat ventral prostate by complementary deoxyribonucleic acid subtraction and microarray. Endocrinology 144:1257-1265
    • (2003) Endocrinology , vol.144 , pp. 1257-1265
    • Jiang, F.1    Wang, Z.2
  • 84
    • 9644273924 scopus 로고    scopus 로고
    • Gene expression profiling identifies a unique androgen-mediated inflammatory/immune signature and a PTEN (phosphatase and tensin homolog deleted on chromosome 10)-mediated apoptotic response specific to the rat ventral prostate
    • Desai KV, Michalowska AM, Kondaiah P, Ward JM, Shih JH, Green JE 2004 Gene expression profiling identifies a unique androgen-mediated inflammatory/immune signature and a PTEN (phosphatase and tensin homolog deleted on chromosome 10)-mediated apoptotic response specific to the rat ventral prostate. Mol Endocrinol 18:2895-2907
    • (2004) Mol Endocrinol , vol.18 , pp. 2895-2907
    • Desai, K.V.1    Michalowska, A.M.2    Kondaiah, P.3    Ward, J.M.4    Shih, J.H.5    Green, J.E.6
  • 88
    • 0041562541 scopus 로고    scopus 로고
    • Involvement of the SREBP pathway in the mode of action of androgens in sebaceous glands in vivo
    • Rosignoli C, Nicolas JC, Jomard A, Michel S 2003 Involvement of the SREBP pathway in the mode of action of androgens in sebaceous glands in vivo. Exp Dermatol 12:480-489
    • (2003) Exp Dermatol , vol.12 , pp. 480-489
    • Rosignoli, C.1    Nicolas, J.C.2    Jomard, A.3    Michel, S.4
  • 91
    • 0023914587 scopus 로고
    • Effects of androgens, prolactin and bromocriptine on seminal vesicular enzymes of the pyruvate malate cycle involved in lipogenesis in castrated mature monkeys, Macaca radiata
    • Arunakaran J, Balasubramanian K, Srinivasan N, Aruldhas MM, Govindarajulu P 1988 Effects of androgens, prolactin and bromocriptine on seminal vesicular enzymes of the pyruvate malate cycle involved in lipogenesis in castrated mature monkeys, Macaca radiata. Int J Androl 11:133-139
    • (1988) Int J Androl , vol.11 , pp. 133-139
    • Arunakaran, J.1    Balasubramanian, K.2    Srinivasan, N.3    Aruldhas, M.M.4    Govindarajulu, P.5
  • 92
    • 0024559456 scopus 로고
    • Control and function of sebaceous glands
    • Thody AJ, Shuster S 1989 Control and function of sebaceous glands. Physiol Rev 69:383-416
    • (1989) Physiol Rev , vol.69 , pp. 383-416
    • Thody, A.J.1    Shuster, S.2
  • 93
    • 0025615535 scopus 로고
    • Effects of prolactin and androgens on the prostatic lipids of castrated mature bonnet monkeys
    • Arunakaran J, Aruldhas MM, Govindarajulu P 1990 Effects of prolactin and androgens on the prostatic lipids of castrated mature bonnet monkeys. Prostate 17:247-260
    • (1990) Prostate , vol.17 , pp. 247-260
    • Arunakaran, J.1    Aruldhas, M.M.2    Govindarajulu, P.3
  • 94
    • 0027520707 scopus 로고
    • Androgen control of sebum production. Studies of subjects with dihydrotestosterone deficiency and complete androgen insensitivity
    • Imperato-McGinley J, Gautier T, Cai LQ, Yee B, Epstein J, Pochi P 1993 Androgen control of sebum production. Studies of subjects with dihydrotestosterone deficiency and complete androgen insensitivity. J Clin Endocrinol Metab 76:524-528
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 524-528
    • Imperato-McGinley, J.1    Gautier, T.2    Cai, L.Q.3    Yee, B.4    Epstein, J.5    Pochi, P.6
  • 96
    • 0035853799 scopus 로고    scopus 로고
    • Progesterone stimulates adipocyte determination and differentiation 1/sterol regulatory element-binding protein 1c gene expression. Potential mechanism for the lipogenic effect of progesterone in adipose tissue
    • Lacasa D, Le Liepvre X, Ferre P, Dugail I 2001 Progesterone stimulates adipocyte determination and differentiation 1/sterol regulatory element-binding protein 1c gene expression. Potential mechanism for the lipogenic effect of progesterone in adipose tissue. J Biol Chem 276:11512-11516
    • (2001) J Biol Chem , vol.276 , pp. 11512-11516
    • Lacasa, D.1    Le Liepvre, X.2    Ferre, P.3    Dugail, I.4
  • 97
    • 0030706079 scopus 로고    scopus 로고
    • Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma
    • Milgraum LZ, Witters LA, Pasternack GR, Kuhajda FP 1997 Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma. Cancer Res 11:2115-2120
    • (1997) Cancer Res , vol.11 , pp. 2115-2120
    • Milgraum, L.Z.1    Witters, L.A.2    Pasternack, G.R.3    Kuhajda, F.P.4
  • 98
    • 0034002793 scopus 로고    scopus 로고
    • Fatty-acid synthase and human cancer: New perspectives on its role in tumor biology
    • Kuhajda FP 2000 Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology. Nutrition 16:202-208
    • (2000) Nutrition , vol.16 , pp. 202-208
    • Kuhajda, F.P.1
  • 99
    • 0036385719 scopus 로고    scopus 로고
    • Activation of fatty acid synthesis during neoplastic transformation: Role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase
    • Yang YA, Han WF, Morin PJ, Chrest FJ, Pizer ES 2002 Activation of fatty acid synthesis during neoplastic transformation: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Exp Cell Res 279:80-90
    • (2002) Exp Cell Res , vol.279 , pp. 80-90
    • Yang, Y.A.1    Han, W.F.2    Morin, P.J.3    Chrest, F.J.4    Pizer, E.S.5
  • 100
    • 0037440477 scopus 로고    scopus 로고
    • Regulation of fatty acid synthase expression in breast cancer by sterol regulatory element binding protein-1c
    • Yang YA, Morin PJ, Han WF, Chen T, Bornman DM, Gabrielson EW, Pizer ES 2003 Regulation of fatty acid synthase expression in breast cancer by sterol regulatory element binding protein-1c. Exp Cell Res 282:132-137
    • (2003) Exp Cell Res , vol.282 , pp. 132-137
    • Yang, Y.A.1    Morin, P.J.2    Han, W.F.3    Chen, T.4    Bornman, D.M.5    Gabrielson, E.W.6    Pizer, E.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.