The hepatic microvascular responses to sepsis

Seminars in Thrombosis and Hemostasis

Volumn 26, Issue 5, 2000, Pages 589-594

  Ring, A ^a   Stremmel, W ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Endothelial cells; Liver; Microcirculation; Sepsis; Sinusoids

Indexed keywords

HUMAN; KUPFFER CELL; LIVER BLOOD FLOW; LIVER SINUSOID; MULTIPLE ORGAN FAILURE; PRIORITY JOURNAL; REVIEW; SEPSIS; SHOCK;

EID: 0033636643     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-13215     Document Type: Review

References (51)

1. Gram-positive organisms and sepsis
2. Pathophysiology and treatment of septic shock
3. Mechanism of hepatocellular dysfunction during hyperdynamic sepsis
4. Untersuchungen uber das choleragift
5. Structure-function relationships of bacterial endotoxins. Contribution to microbial sepsis
6. The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure
7. Pneumolysin, a protein toxin of Streptococcus pneumoniae, induces nitric oxide production from macrophages
8. Pore-forming bacterial toxins potently induce release of nitric oxide in porcine endothelial cells
9. Pyrogenic exotoxins (superantigens) (Staphylococcus aureus and Streptococcus pyogenes)
10. Bacterial DNA causes septic shock
11. Bacterial DNA as immune cell activator
12. Detection of circulating tumor necrosis factor after endotoxin administration
13. Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans
14. IL-18 accounts for both TNF-alpha- and Fas ligand-mediated hepatotoxic pathways in endotoxin-induced liver injury in mice
15. Caspase-1-independent, Fas/Fas ligand-mediated IL-18 secretion from macrophages causes acute liver injury in mice
16. Increased plasma levels of interleukin-6 in sepsis
17. Elevated production of interleukin 6 by hepatic MNC correlates with ICAM-1 expression on the hepatic sinusoidal endothelial cells in autoimmune MRL/lpr mice
18. Bakterielle Endotoxine als Ausloser des septischen Schocks: Konstitution, Wirkung und Neutralisation
19. Role of interleukin 6 and transforming growth factor-beta in the induction of depressed splenocyte responses following sepsis
20. Regulation of endotoxin-induced IL-6 production in liver sinusoidal endothelial cells and Kupffer cells by IL-10
21. Interferon gamma-1b in the treatment of compensatory anti-inflammatory response syndrome. A new approach: Proof of principle
22. Nitric oxide synthase isoform III gene expression in rat liver is up-regulated by lipopolysaccharide and lipoteichoic acid
23. Regulation and function of inducible nitric oxide synthase during sepsis and acute inflammation
24. Role of nitric oxide in maintaining vascular integrity of endotoxin-induced acute intestinal damage in the rat
25. Nitric oxide donor prevents hepatic and systemic perfusion decrease induced by endotoxin in anesthetized rabbits
26. Mechanisms of liver damage
27. ET-1 induced alterations of hepatic microcirculation: Sinusoidal and extrasinusoidal sites of action
28. Responses of the hepatic sinusoid lining and microcirculation to combinations of endotoxin, cytokines and ethanol
29. Endotoxin stimulates gene expression of ROS-eliminating pathways in rat hepatic endothelial and Kupffer cells
30. Glucose utilization by Kupffer cells, endothelial cells, and granulocytes in endotoxemic rat liver
31. Potential role of hepatic macrophages in neutrophil-mediated liver injury in rats with sepsis
32. Effect of immunoglobulin G on the hepatic microvascular inflammatory response during sepsis
33. Expression patterns of leukocyte adhesion ligand molecules on human liver endothelia. Lack of ELAM-1 and CD62 inducibility on sinusoidal endothelia and distinct distribution of VCAM-1, ICAM-1, ICAM-2, and LFA-3
34. Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice
35. Tumor necrosis factor-α produces hepatocellular dysfunction despite normal cardiac output and hepatic microcirculation
36. Role of lipopolysaccharide and tumor necrosis factor-α in induction of hepatocyte necrosis
37. Mechanism of hepatocellular dysfunction during early sepsis
38. Hepatocellular dysfunction occurs earlier than the onset of hyperdynamic circulation during sepsis
39. Nitric oxide. To block or enhance its production during sepsis?
40. Beneficial versus detrimental effects of nitric oxide synthase inhibitors in circulatory shock: Lessons learned from experimental and clinical studies
41. Nitric oxide synthesis serves to reduce hepatic damage during acute murine endotoxemia
42. Differential effect of 2-aminoethyl-isothiourea, an inhibitor of the inducible nitric oxide synthase, on microvascular blood flow and organ injury in models of hepatic ischemia-reperfusion and endotoxemia
43. Endothelin-1 as a regulator of hepatic microcirculation: Sublobular distribution of effects and impact on hepatocellular secretory function
44. ET-1 induced alterations of hepatic microcirculation: Sinusoidal and extrasinusoidal sites of action
45. Ito cell contraction in response to endothelin-1 and substance P
46. Endothelin receptors in rat liver: Lipocytes as a contractile target for endothelin 1
47. Characterization of endothelin receptors mediating rat hepatic stellate cell contraction
48. Effect of selective blockade of endothelin ETB receptors on the liver dysfunction and injury caused by endotoxaemia in the rat
49. Endothelin-1 induces vasoconstriction and nitric oxide release via endothelin ET(B) receptors in isolated perfused rat liver
50. Carbon monoxide: An endogenous modulator of sinusoidal tone in the perfused rat liver
51. Heme oxygenase-dependent carbon monoxide production is a hepatic adaptive response to sepsis