Binding of two potential imaging agents targeting amyloid plaques in postmortem brain tissues of patients with Alzheimer's disease

Brain Research

Volumn 1025, Issue 1-2, 2004, Pages 98-105

  Kung, Mei Ping ^a   Hou, Catherine ^a   Zhuang, Zhi Ping ^a   Skovronsky, Daniel ^a   Kung, Hank F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Amyloid plaque; Brain imaging; Homogenate binding; PET; SPECT

Indexed keywords

2,3 DIHYDRO 1H IMIDAZO[1,2 B]PYRAZOLE; AMYLOID; CARBON 11; IODINE 123; LIGAND; N METHYLAMINO 4' HYDROXYSTILBENE; THIOFLAVINE; UNCLASSIFIED DRUG;

AGED; ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN CORTEX; BRAIN HOMOGENATE; BRAIN TISSUE; CADAVER; CEREBELLUM; CONTROLLED STUDY; DENSITY; GRAY MATTER; HUMAN; HUMAN TISSUE; IMAGING SYSTEM; IN VIVO STUDY; ISOTOPE LABELING; MOLECULAR PROBE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STAINING; TARGET ORGAN; TISSUE HOMOGENATE; WHITE MATTER;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; HUMANS; POSITRON-EMISSION TOMOGRAPHY; PROTEIN BINDING; PYRIDINES; RADIOISOTOPES; SENILE PLAQUES; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 5444264488     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.08.004     Document Type: Article

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