-
1
-
-
0032568150
-
Stabilization of wild-type p53 by hypoxia-iducible factor 1 alpha
-
An, W.G., M. Kanekal, M.C. Simon, E. Maltepe, M.V. Blagosklonny, and L.M. Neckers. 1998. Stabilization of wild-type p53 by hypoxia-iducible factor 1 alpha. Nature 392: 405-408.
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
Kanekal, M.2
Simon, M.C.3
Maltepe, E.4
Blagosklonny, M.V.5
Neckers, L.M.6
-
3
-
-
0029842459
-
Oxygen sensing and molecular adaptation to hypoxia
-
Bunn, H.F. and R.O. Poyton. 1996. Oxygen sensing and molecular adaptation to hypoxia. Physiol. Rev. 76: 839-885.
-
(1996)
Physiol. Rev.
, vol.76
, pp. 839-885
-
-
Bunn, H.F.1
Poyton, R.O.2
-
4
-
-
0032581277
-
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis
-
Carmeliet, P., Y. Dor, J.M. Herbert, D. Fukumura, K. Brusselmans, M. Dewerchin, M. Neeman, F. Bono, R. Abramovitch, P. Maxwell, C.J. Koch, P. Ratcliffe, L. Moons, R.K. Jain, D. Collen, and E. Keshet. 1998. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis. Nature 394: 485-490.
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
Neeman, M.7
Bono, F.8
Abramovitch, R.9
Maxwell, P.10
Koch, C.J.11
Ratcliffe, P.12
Moons, L.13
Jain, R.K.14
Collen, D.15
Keshet, E.16
-
5
-
-
0031932209
-
A common precursor for hematopoietic and endothelial cells
-
Choi, K. M. Kennedy, A. Kazarov, J.C. Papadimitriou, and G. Keller. 1998. A common precursor for hematopoietic and endothelial cells. Development 125: 725-832.
-
(1998)
Development
, vol.125
, pp. 725-832
-
-
Choi1
Kennedy, K.M.2
Kazarov, A.3
Papadimitriou, J.C.4
Keller, G.5
-
6
-
-
0033136719
-
Self-renewal, differentiation or death: Regulation and manipulation of hematopoietic stem cell fate
-
Domen, J. and I.L. Weissman. 1999. Self-renewal, differentiation or death: Regulation and manipulation of hematopoietic stem cell fate. Mol. Med. Today 5: 201-208.
-
(1999)
Mol. Med. Today
, vol.5
, pp. 201-208
-
-
Domen, J.1
Weissman, I.L.2
-
7
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
Ferrara, N., K. Carver-Moore, H. Chen, M. Dowd, L. Lu, K.S. O'Shea, L. Powell-Braxton, K.J. Hillan, and M.W. Moore. 1996. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380: 439-442.
-
(1996)
Nature
, vol.380
, pp. 439-442
-
-
Ferrara, N.1
Carver-Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O'Shea, K.S.6
Powell-Braxton, L.7
Hillan, K.J.8
Moore, M.W.9
-
8
-
-
0027756119
-
Oxygen tension in the oviduct and uterus of rhesus monkeys, hamsters and rabbits
-
Fischer, B. and B.D. Bavister. 1993. Oxygen tension in the oviduct and uterus of rhesus monkeys, hamsters and rabbits. J. Reprod. Fertil. 99: 673-679.
-
(1993)
J. Reprod. Fertil.
, vol.99
, pp. 673-679
-
-
Fischer, B.1
Bavister, B.D.2
-
9
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe, J.A., B.H. Jiang, N.V. Iyer, F. Agani, S.W. Leung, R.D. Koos, and G.L. Semenza. 1996. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell. Biol. 16: 4604-4613.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
Agani, F.4
Leung, S.W.5
Koos, R.D.6
Semenza, G.L.7
-
10
-
-
0029866447
-
Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells
-
Gassmann, M., J. Fanrey, S. Bichet, M. Wartenberg, H.H. Marti, C. Bauer, R.H. Wenger, and H. Acker. 1996. Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells. Proc. Natl. Acad. Sci. 93: 2867-2872.
-
(1996)
Proc. Natl. Acad. Sci.
, vol.93
, pp. 2867-2872
-
-
Gassmann, M.1
Fanrey, J.2
Bichet, S.3
Wartenberg, M.4
Marti, H.H.5
Bauer, C.6
Wenger, R.H.7
Acker, H.8
-
11
-
-
0030879909
-
Regulation of humna placental development by oxygen tension
-
Genbacev, O., Y. Zhou, J.W. Ludlow, and S.J. Fisher. 1997. Regulation of humna placental development by oxygen tension. Science 277: 1669-1672.
-
(1997)
Science
, vol.277
, pp. 1669-1672
-
-
Genbacev, O.1
Zhou, Y.2
Ludlow, J.W.3
Fisher, S.J.4
-
12
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
Graeber, T.G., C. Osmanian, T. Jacks, D.E. Housman, C.J. Koch, S.W. Lowe, and A.J. Giaccia. 1996. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 379: 88-91.
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
Housman, D.E.4
Koch, C.J.5
Lowe, S.W.6
Giaccia, A.J.7
-
13
-
-
0033594913
-
Conditional requirement for the flk-1 receptor in the in vitro generation of early hematopoietic cells
-
Hidaka, M., W.L. Stanford, and A. Bernstein. 1999. Conditional requirement for the flk-1 receptor in the in vitro generation of early hematopoietic cells. Proc. Natl. Acad. Sci. 96: 7370-7375.
-
(1999)
Proc. Natl. Acad. Sci.
, vol.96
, pp. 7370-7375
-
-
Hidaka, M.1
Stanford, W.L.2
Bernstein, A.3
-
14
-
-
15444342958
-
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
-
Iyer, N.V., L.E. Kotch, F. Agani, S.W. Leung, E. Laughner, R.H. Wenger, M. Gassmann, J.D. Gearhart, A.M. Lawler, A.Y. Yu, and G.L. Semenza. 1998. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes & Dev. 12: 149-162.
-
(1998)
Genes & Dev.
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
Leung, S.W.4
Laughner, E.5
Wenger, R.H.6
Gassmann, M.7
Gearhart, J.D.8
Lawler, A.M.9
Yu, A.Y.10
Semenza, G.L.11
-
15
-
-
0032403016
-
Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor
-
Katoh, O., T. Takahashi, T. Oguri, K. Kuramoto, K. Mihara, M. Kobayashi, S. Hirata, and H. Watanabe. 1998. Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor. Cancer Res. 58: 5565-5569.
-
(1998)
Cancer Res.
, vol.58
, pp. 5565-5569
-
-
Katoh, O.1
Takahashi, T.2
Oguri, T.3
Kuramoto, K.4
Mihara, K.5
Kobayashi, M.6
Hirata, S.7
Watanabe, H.8
-
16
-
-
0027389676
-
Hematopoietic commitment during embryonic stem cell differentiation in culture
-
Keller, G., M. Kennedy, T. Papayannopoulou, and M.V. Wiles. 1993. Hematopoietic commitment during embryonic stem cell differentiation in culture. Mol. Cell. Biol. 13: 472-486.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 472-486
-
-
Keller, G.1
Kennedy, M.2
Papayannopoulou, T.3
Wiles, M.V.4
-
17
-
-
0030942527
-
A common precursor for primitive erythropoiesis and definitive haematopoiesis
-
Kennedy, M., M. Firpo, K. Choi, C. Wall, S. Robertson, N. Kabrun, and G. Keller. 1997. A common precursor for primitive erythropoiesis and definitive haematopoiesis. Nature 386: 488-493.
-
(1997)
Nature
, vol.386
, pp. 488-493
-
-
Kennedy, M.1
Firpo, M.2
Choi, K.3
Wall, C.4
Robertson, S.5
Kabrun, N.6
Keller, G.7
-
18
-
-
17544384815
-
ARNT-deficient mice and placental differentiation
-
Kozak, K.R., B. Abbott, and O. Hankinson. 1997. ARNT-deficient mice and placental differentiation. Dev. Biol. 191: 297-305.
-
(1997)
Dev. Biol.
, vol.191
, pp. 297-305
-
-
Kozak, K.R.1
Abbott, B.2
Hankinson, O.3
-
19
-
-
0030050404
-
Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis
-
Lin, C.S., S.K. Lim, V.D'Agati, and F. Costantini. 1996. Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. Genes & Dev. 10: 154-164.
-
(1996)
Genes & Dev.
, vol.10
, pp. 154-164
-
-
Lin, C.S.1
Lim, S.K.2
D'Agati, V.3
Costantini, F.4
-
20
-
-
0022911397
-
Enhanced colony formation of human hemopoietic stem cells in reduced oxygen tension
-
Maeda, H., T. Hotta, and H. Yamada. 1986. Enhanced colony formation of human hemopoietic stem cells in reduced oxygen tension. Exp. Hematol. 14: 930-934.
-
(1986)
Exp. Hematol.
, vol.14
, pp. 930-934
-
-
Maeda, H.1
Hotta, T.2
Yamada, H.3
-
21
-
-
0030943461
-
Abnormal angiogenesis and responses to glucose and oxygen depravation in mice lacking the protein ARNT
-
Maltepe, E., J.V. Schmidt, D. Baunoch, C.A. Bradfield, and M.C. Simon. 1997. Abnormal angiogenesis and responses to glucose and oxygen depravation in mice lacking the protein ARNT. Nature 386: 403-407.
-
(1997)
Nature
, vol.386
, pp. 403-407
-
-
Maltepe, E.1
Schmidt, J.V.2
Baunoch, D.3
Bradfield, C.A.4
Simon, M.C.5
-
22
-
-
0031969557
-
Oxygen, genes, and development: An analyis of the role of hypoxic gene regulation during murine vascular development
-
Maltepe, E. and M.C. Simon. 1998. Oxygen, genes, and development: An analyis of the role of hypoxic gene regulation during murine vascular development. J. Mol. Med. 76: 391-401.
-
(1998)
J. Mol. Med.
, vol.76
, pp. 391-401
-
-
Maltepe, E.1
Simon, M.C.2
-
23
-
-
0030595341
-
Definitive hematopoiesis is autonomously initiated by the AGM region
-
Medvinsky, A. and E. Dzierzak. 1996. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 86: 897-906.
-
(1996)
Cell
, vol.86
, pp. 897-906
-
-
Medvinsky, A.1
Dzierzak, E.2
-
24
-
-
0026773795
-
Production of homozygous mutant ES cells with a single targeting construct
-
Mortensen, R.M., D.A. Conner, S. Chao, A.A. Geisterfer-Lowrance, and J.G. Seidman. 1992. Production of homozygous mutant ES cells with a single targeting construct. Mol. Cell. Biol. 12: 2491-2395.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2491-12395
-
-
Mortensen, R.M.1
Conner, D.A.2
Chao, S.3
Geisterfer-Lowrance, A.A.4
Seidman, J.G.5
-
25
-
-
0029550341
-
PU.1 is not essential for early myeloid gene expression but is required fro terminal myeloid differentiation
-
Olson, M.C., E.W. Scott, A.A. Hack, G.H. Su, D.G. Tenen, H. Singh, and M.C. Simon. 1995. PU.1 is not essential for early myeloid gene expression but is required fro terminal myeloid differentiation. Immunity 3: 703-714.
-
(1995)
Immunity
, vol.3
, pp. 703-714
-
-
Olson, M.C.1
Scott, E.W.2
Hack, A.A.3
Su, G.H.4
Tenen, D.G.5
Singh, H.6
Simon, M.C.7
-
26
-
-
0029034799
-
Hypoxia induces capillary network formation in cultured bovine pulmonary microvessel endothelial cell
-
Phillips, P.G., L.M. Birnby, and A. Narendran. 1995. Hypoxia induces capillary network formation in cultured bovine pulmonary microvessel endothelial cell. Am. J. Physiol. 268: L789-800.
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Phillips, P.G.1
Birnby, L.M.2
Narendran, A.3
-
27
-
-
0029781248
-
The sc1 gene product is required for the generation of all hematopoietic lineages in the adult mouse
-
Robb, L., N.J. Elwood, A.C. Elefanty, F. Kontgen, R. Li, L.D. Barnett, and C.G. Begley. 1996. The sc1 gene product is required for the generation of all hematopoietic lineages in the adult mouse. EMBO J. 15: 4123-4129.
-
(1996)
EMBO J.
, vol.15
, pp. 4123-4129
-
-
Robb, L.1
Elwood, N.J.2
Elefanty, A.C.3
Kontgen, F.4
Li, R.5
Barnett, L.D.6
Begley, C.G.7
-
28
-
-
0026782588
-
Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy
-
Rodesch, F., P. Simon, C. Donner, and E. Jauniaux. 1992. Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstet. Gynecol. 80: 283-285.
-
(1992)
Obstet. Gynecol.
, vol.80
, pp. 283-285
-
-
Rodesch, F.1
Simon, P.2
Donner, C.3
Jauniaux, E.4
-
29
-
-
0032100732
-
HIF-1a is required for solid tumor formation and embyonic vascularization
-
Ryan, H.E., J. Lo, and R.S. Johnson. 1998. HIF-1a is required for solid tumor formation and embyonic vascularization. EMBO J. 17: 3005-3015.
-
(1998)
EMBO J.
, vol.17
, pp. 3005-3015
-
-
Ryan, H.E.1
Lo, J.2
Johnson, R.S.3
-
30
-
-
0030961006
-
Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
-
Salceda, S. and J. Caro. 1997. Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J. Biol. Chem. 272: 22642-22647.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22642-22647
-
-
Salceda, S.1
Caro, J.2
-
31
-
-
0033515089
-
In vitro hematopoietic and endothelial potential of flk-1(-/-) embryonic stem cells and embryos
-
Schuh, A.C., P. Faloon, Q.L. Hu, M. Bhimani, and K. Choi. 1999. In vitro hematopoietic and endothelial potential of flk-1(-/-) embryonic stem cells and embryos. Proc. Natl. Acad. Sci. 96: 2159-2164.
-
(1999)
Proc. Natl. Acad. Sci.
, vol.96
, pp. 2159-2164
-
-
Schuh, A.C.1
Faloon, P.2
Hu, Q.L.3
Bhimani, M.4
Choi, K.5
-
32
-
-
0026075610
-
Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene
-
Semenza, G.L., M.K. Nejfelt, S.M. Chi, and S.E. Antonarakis. 1991. Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene. Proc. Natl. Acad. Sci. 88: 5680-5684.
-
(1991)
Proc. Natl. Acad. Sci.
, vol.88
, pp. 5680-5684
-
-
Semenza, G.L.1
Nejfelt, M.K.2
Chi, S.M.3
Antonarakis, S.E.4
-
33
-
-
0030460724
-
Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
-
Semenza, G.L., B.H. Jiang, S.W. Leung, R. Passantino, J.P. Concordet, P. Maire, and A. Giallongo. 1996. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J. Biol. Chem. 271: 32529-32537.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32529-32537
-
-
Semenza, G.L.1
Jiang, B.H.2
Leung, S.W.3
Passantino, R.4
Concordet, J.P.5
Maire, P.6
Giallongo, A.7
-
34
-
-
0030831104
-
A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis
-
Shalaby, F., J. Ho, W.L. Stanford, K.D. Fischer, A.C. Schuh, L. Schwartz, A. Bernstein, and J. Rossant. 1997. A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89: 981-990.
-
(1997)
Cell
, vol.89
, pp. 981-990
-
-
Shalaby, F.1
Ho, J.2
Stanford, W.L.3
Fischer, K.D.4
Schuh, A.C.5
Schwartz, L.6
Bernstein, A.7
Rossant, J.8
-
35
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Schweiki, D., A. Itin, D. Soffer, and E. Keshet. 1992. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359: 843-845.
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Schweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
36
-
-
0000418386
-
The TEL/ ETV6 gene is required specifically for hematopoiesis in the bone marrow
-
Wang, L.C., W. Swat, Y. Fujiwara, L. Davidson, J. Visvader, F. Kuo, F.W. Alt, D.G. Gilliland, T.R. Golub, and S.H. Orkin. 1998. The TEL/ ETV6 gene is required specifically for hematopoiesis in the bone marrow. Genes & Dev. 12: 2392-2402.
-
(1998)
Genes & Dev.
, vol.12
, pp. 2392-2402
-
-
Wang, L.C.1
Swat, W.2
Fujiwara, Y.3
Davidson, L.4
Visvader, J.5
Kuo, F.6
Alt, F.W.7
Gilliland, D.G.8
Golub, T.R.9
Orkin, S.H.10
-
37
-
-
1842416574
-
Oxygen(es) and the hypoxia-inducible factor-1
-
Wenger, R.H. and M. Gassmann. 1997. Oxygen(es) and the hypoxia-inducible factor-1. Biol. Chem. 378: 609-616.
-
(1997)
Biol. Chem.
, vol.378
, pp. 609-616
-
-
Wenger, R.H.1
Gassmann, M.2
-
38
-
-
0032189844
-
Induction of endothelial PAS domain protein-1 by hypoxia: Characterization and comparison with hypoxia-inducible factor-1alpha
-
Wiesener, M.S., H. Turley, W.E. Allen, C. Willam, K.U. Eckardt, K.L. Talks, S.M. Wood, K.C. Gatter, A.L. Harris, C.W. Pugh, P.J. Ratcliffe, and P.H. Maxwell. 1998. Induction of endothelial PAS domain protein-1 by hypoxia: Characterization and comparison with hypoxia-inducible factor-1alpha. Blood 92: 2260-2268.
-
(1998)
Blood
, vol.92
, pp. 2260-2268
-
-
Wiesener, M.S.1
Turley, H.2
Allen, W.E.3
Willam, C.4
Eckardt, K.U.5
Talks, K.L.6
Wood, S.M.7
Gatter, K.C.8
Harris, A.L.9
Pugh, C.W.10
Ratcliffe, P.J.11
Maxwell, P.H.12
-
39
-
-
0029888061
-
The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells
-
Wood, S.M., J.M. Gleadle, C.W. Pugh, O. Hankinson, and P.J. Ratcliffe. 1996. The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells. J. Biol. Chem. 271: 15117-15123.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15117-15123
-
-
Wood, S.M.1
Gleadle, J.M.2
Pugh, C.W.3
Hankinson, O.4
Ratcliffe, P.J.5
-
40
-
-
0028880455
-
Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor
-
Wu, H., X. Liu, R. Jaenisch, and H.F. Lodish. 1995. Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell 83: 59-67.
-
(1995)
Cell
, vol.83
, pp. 59-67
-
-
Wu, H.1
Liu, X.2
Jaenisch, R.3
Lodish, H.F.4
|