Inhibitors of factor VIIa affect the interface between the protease domain and tissue factor

Biochemical and Biophysical Research Communications

Volumn 349, Issue 3, 2006, Pages 1111-1116

  Carlsson, Karin ^a   Persson, Egon ^b   Carlsson, Uno ^a   Svensson, Magdalena ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

^b NOVO NORDISK A S   (Denmark)

Author keywords

Active site inhibitor; Allostery; Exosite inhibitor; Factor VIIa; Fluorescent probe; Protein protein interaction; Tissue factor

Indexed keywords

A 183; BLOOD CLOTTING FACTOR 7A INHIBITOR; CYSTEINE; E 76; KETONE DERIVATIVE; PROTEINASE; THROMBOPLASTIN; TISSUE FACTOR PATHWAY INHIBITOR; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; PRIORITY JOURNAL; PROTEIN BINDING; STRUCTURE ANALYSIS;

BINDING SITES; FACTOR VIIA; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; SPECTROMETRY, FLUORESCENCE; THROMBOPLASTIN;

EID: 33748585489     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.08.148     Document Type: Article

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