메뉴 건너뛰기




Volumn 166, Issue 3, 2006, Pages 463-473

Overexpression of MDR1 using a retroviral vector differentially regulates genes involved in detoxification and apoptosis and confers radioprotection

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; RETROVIRUS VECTOR;

EID: 33748471486     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR0550.1     Document Type: Article
Times cited : (23)

References (57)
  • 1
    • 14044253040 scopus 로고    scopus 로고
    • Combining radiation and molecular targeting in cancer therapy
    • K. Camphausen and P. J. Tofilon, Combining radiation and molecular targeting in cancer therapy. Cancer Biol. Ther. 3, 247-250 (2004).
    • (2004) Cancer Biol. Ther. , vol.3 , pp. 247-250
    • Camphausen, K.1    Tofilon, P.J.2
  • 2
    • 19144361831 scopus 로고    scopus 로고
    • Frequency analysis of multidrug resistance-1 gene transfer into human primitive hematopoietic progenitor cells using the cobblestone area-forming cell assay and detection of vector-mediated P-glycoprotein expression by rhodamine-123
    • S. Fruehauf, D. A. Breems, S. Knaan-Shanzer, K. B. Brouwer, R. Haas, B. Lowenberg, K. Nooter, R. E. Ploemacher, D. Valerio and J. J. Boesen, Frequency analysis of multidrug resistance-1 gene transfer into human primitive hematopoietic progenitor cells using the cobblestone area-forming cell assay and detection of vector-mediated P-glycoprotein expression by rhodamine-123. Hum. Gene Ther. 1, 1219-1231 (1996).
    • (1996) Hum. Gene Ther. , vol.1 , pp. 1219-1231
    • Fruehauf, S.1    Breems, D.A.2    Knaan-Shanzer, S.3    Brouwer, K.B.4    Haas, R.5    Lowenberg, B.6    Nooter, K.7    Ploemacher, R.E.8    Valerio, D.9    Boesen, J.J.10
  • 3
    • 4444277816 scopus 로고    scopus 로고
    • Combining gene therapy and radiation against cancer
    • D. S. Gridley and J. M. Slater, Combining gene therapy and radiation against cancer. Curr. Gene Ther. 4, 231-248 (2004).
    • (2004) Curr. Gene Ther. , vol.4 , pp. 231-248
    • Gridley, D.S.1    Slater, J.M.2
  • 5
    • 0034798720 scopus 로고    scopus 로고
    • Keratinocyte growth factors radioprotect bowel and bone marrow but not KHT sarcoma
    • J. P. Okunieff, M. Li, W. Liu, J. Sun, B. Fenton, L. Zhang and I. Ding, Keratinocyte growth factors radioprotect bowel and bone marrow but not KHT sarcoma. Am. J. Clin. Oncol. 24, 491-495 (2001).
    • (2001) Am. J. Clin. Oncol. , vol.24 , pp. 491-495
    • Okunieff, J.P.1    Li, M.2    Liu, W.3    Sun, J.4    Fenton, B.5    Zhang, L.6    Ding, I.7
  • 6
    • 18144385121 scopus 로고    scopus 로고
    • Effects of keratinocyte growth factor (palifermin) administration protocols on oral mucositis (mouse) induced by fractionated irradiation
    • W. Dorr, S. Reichel and K. Spekl, Effects of keratinocyte growth factor (palifermin) administration protocols on oral mucositis (mouse) induced by fractionated irradiation. Radiother. Oncol. 75, 99-105 (2005).
    • (2005) Radiother. Oncol. , vol.75 , pp. 99-105
    • Dorr, W.1    Reichel, S.2    Spekl, K.3
  • 7
    • 26944437739 scopus 로고    scopus 로고
    • Palifermin: In myelotoxic therapy-induced oral mucositis
    • M. A. Siddiqui and K. Wellington, Palifermin: In myelotoxic therapy-induced oral mucositis. Drugs 65, 2139-2147 (2005).
    • (2005) Drugs , vol.65 , pp. 2139-2147
    • Siddiqui, M.A.1    Wellington, K.2
  • 9
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • M. M. Gottesman and I. Pastan, Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem. 62, 385-427 (1993).
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 10
    • 0025799513 scopus 로고
    • Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells
    • P. M. Chaudhary and I. B. Roninson, Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 66, 85-94 (1991).
    • (1991) Cell , vol.66 , pp. 85-94
    • Chaudhary, P.M.1    Roninson, I.B.2
  • 11
    • 0031972859 scopus 로고    scopus 로고
    • Phase I trial of retro viral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation
    • C. Hesdorffer, J. Ayello, M. Ward, A. Kaubisch, L. Vahdat, C. Balmaceda, T. Garrett, M. Fetell, R. Reiss and K. Antman, Phase I trial of retro viral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation. J. Clin. Oncol. 16, 165-172 (1998).
    • (1998) J. Clin. Oncol. , vol.16 , pp. 165-172
    • Hesdorffer, C.1    Ayello, J.2    Ward, M.3    Kaubisch, A.4    Vahdat, L.5    Balmaceda, C.6    Garrett, T.7    Fetell, M.8    Reiss, R.9    Antman, K.10
  • 12
    • 22944443333 scopus 로고    scopus 로고
    • Transfer of the multidrug resistance gene, MDR-1, to hematopoietic progenitors from a patient with transformed large cell lymphoma, and demonstration of in vivo chemotherapy protection with dose escalating chemotherapy
    • abstract
    • P. S. Becker, Y. P. Yu, A. M. Ceredona, W. V. Walsh, J. L. O'Donnell, C. Baum, L. Kallander, P. A. Lowry, T. J. Fitzgerald and F. M. Stewart, Transfer of the multidrug resistance gene, MDR-1, to hematopoietic progenitors from a patient with transformed large cell lymphoma, and demonstration of in vivo chemotherapy protection with dose escalating chemotherapy. Blood 104, 5278 (2004). [abstract]
    • (2004) Blood , vol.104 , pp. 5278
    • Becker, P.S.1    Yu, Y.P.2    Ceredona, A.M.3    Walsh, W.V.4    O'Donnell, J.L.5    Baum, C.6    Kallander, L.7    Lowry, P.A.8    Fitzgerald, T.J.9    Stewart, F.M.10
  • 13
    • 0032809319 scopus 로고    scopus 로고
    • Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retro virus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients
    • K. H. Cowan, J. A. Moscow, H. Huang, J. A. Zujewski, J. O'Shaughnessy, B. Sorrentino, K. Hines, C. Carter, E. Schneider and A. Nienhuis, Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retro virus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients. Clin. Cancer Res. 5, 1619-1628 (1999).
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1619-1628
    • Cowan, K.H.1    Moscow, J.A.2    Huang, H.3    Zujewski, J.A.4    O'Shaughnessy, J.5    Sorrentino, B.6    Hines, K.7    Carter, C.8    Schneider, E.9    Nienhuis, A.10
  • 15
    • 0036286183 scopus 로고    scopus 로고
    • Hematologic consequences of exposure to ionizing radiation
    • N. Dainiak, Hematologic consequences of exposure to ionizing radiation. Exp. Hematol. 30, 513-528 (2002).
    • (2002) Exp. Hematol. , vol.30 , pp. 513-528
    • Dainiak, N.1
  • 16
    • 0026070244 scopus 로고
    • Radiation sensitivity of the hemopoietic stem cell
    • D. W. van Bekkum, Radiation sensitivity of the hemopoietic stem cell. Radiat. Res. 128 (Suppl.), S4-S8 (1991).
    • (1991) Radiat. Res. , vol.128 , Issue.SUPPL.
    • Van Bekkum, D.W.1
  • 18
    • 0018118326 scopus 로고
    • Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: Possibility for a rapid human cell mutation assay
    • T. R. Skopek, H. L. Liber, B. W. Penman and W. G. Thilly, Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: Possibility for a rapid human cell mutation assay. Biochem. Biophys. Res. Commun. 84, 411-416 (1978).
    • (1978) Biochem. Biophys. Res. Commun. , vol.84 , pp. 411-416
    • Skopek, T.R.1    Liber, H.L.2    Penman, B.W.3    Thilly, W.G.4
  • 21
    • 0342470476 scopus 로고    scopus 로고
    • Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice
    • B. Schiedlmeier, K. Kuhlcke, H. G. Eckert, C. Baum, W. J. Zeller and S. Fruehauf, Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice. Blood 95, 1237-1248 (2000).
    • (2000) Blood , vol.95 , pp. 1237-1248
    • Schiedlmeier, B.1    Kuhlcke, K.2    Eckert, H.G.3    Baum, C.4    Zeller, W.J.5    Fruehauf, S.6
  • 22
    • 0036126861 scopus 로고    scopus 로고
    • A systematic statistical linear modeling approach to oligonucleotide array experiments
    • T. M. Chu, B. Weir and R. Wolfinger, A systematic statistical linear modeling approach to oligonucleotide array experiments. Math. Biosci. 176, 35-51 (2002).
    • (2002) Math. Biosci. , vol.176 , pp. 35-51
    • Chu, T.M.1    Weir, B.2    Wolfinger, R.3
  • 23
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • I. Nicoletti, G. Migliorati, M. C. Pagliacci, F. Grignani and C. Riccardi, A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139, 271-279 (1991).
    • (1991) J. Immunol. Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 24
    • 0019404906 scopus 로고
    • Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates
    • E. E. Furth, W. G. Thilly, B. W. Penman, H. L. Liber and W. M. Rand, Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates. Anal. Biochem. 110, 1-8 (1981).
    • (1981) Anal. Biochem. , vol.110 , pp. 1-8
    • Furth, E.E.1    Thilly, W.G.2    Penman, B.W.3    Liber, H.L.4    Rand, W.M.5
  • 25
    • 0034131481 scopus 로고    scopus 로고
    • Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells
    • R. Abonour, D. A. Williams, L. Einhorn, K. M. Hall, J. Chen, J. Coffman, C. M. Traycoff, A. Bank, I. Kato and K. Cornetta, Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells. Nat. Med. 6, 652-658 (2000).
    • (2000) Nat. Med. , vol.6 , pp. 652-658
    • Abonour, R.1    Williams, D.A.2    Einhorn, L.3    Hall, K.M.4    Chen, J.5    Coffman, J.6    Traycoff, C.M.7    Bank, A.8    Kato, I.9    Cornetta, K.10
  • 26
    • 0036169083 scopus 로고    scopus 로고
    • Multidrug resistance I gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice
    • B. Schiedlmeier, A. J. Schilz, K. Kuhlcke, S. Laufs, C. Baum, W. J. Zeller, H. G. Eckert and S. Fruehauf, Multidrug resistance I gene transfer can confer chemoprotection to human peripheral blood progenitor cells engrafted in immunodeficient mice. Hum. Gene Ther. 13, 233-242 (2002).
    • (2002) Hum. Gene Ther. , vol.13 , pp. 233-242
    • Schiedlmeier, B.1    Schilz, A.J.2    Kuhlcke, K.3    Laufs, S.4    Baum, C.5    Zeller, W.J.6    Eckert, H.G.7    Fruehauf, S.8
  • 27
    • 2542457495 scopus 로고    scopus 로고
    • Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
    • F. Martinon and J. Tschopp, Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases. Cell 117, 561-574 (2004).
    • (2004) Cell , vol.117 , pp. 561-574
    • Martinon, F.1    Tschopp, J.2
  • 28
    • 0030852882 scopus 로고    scopus 로고
    • Lack of uncoupling of S phase and mitosis after irradiation in p53-human lymphoblast cell lines
    • F. Wenz, Y. Yu, H. Nagasawa, A. C. Imrich, P. Keng and J. B. Little, Lack of uncoupling of S phase and mitosis after irradiation in p53-human lymphoblast cell lines. Radiat. Res. 148, 129-134 (1997).
    • (1997) Radiat. Res. , vol.148 , pp. 129-134
    • Wenz, F.1    Yu, Y.2    Nagasawa, H.3    Imrich, A.C.4    Keng, P.5    Little, J.B.6
  • 29
    • 0031983319 scopus 로고    scopus 로고
    • The response of proliferating cell nuclear antigen to ionizing radiation in human lymphoblastoid cell lines is dependent on p53
    • F. Wenz, E. I. Azzam and J. B. Little, The response of proliferating cell nuclear antigen to ionizing radiation in human lymphoblastoid cell lines is dependent on p53. Radiat. Res. 149, 32-40 (1998).
    • (1998) Radiat. Res. , vol.149 , pp. 32-40
    • Wenz, F.1    Azzam, E.I.2    Little, J.B.3
  • 30
    • 0029200154 scopus 로고
    • Quantification of apoptotic events in pure and heterogeneous populations of cells using the flow cytometer
    • P. J. Fraker, L. E. King, D. Lill-Elghanian and W. G. Telford, Quantification of apoptotic events in pure and heterogeneous populations of cells using the flow cytometer. Methods Cell Biol. 46, 57-76 (1995).
    • (1995) Methods Cell Biol. , vol.46 , pp. 57-76
    • Fraker, P.J.1    King, L.E.2    Lill-Elghanian, D.3    Telford, W.G.4
  • 31
    • 0028990145 scopus 로고
    • Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status
    • J. B. Little, H. Nagasawa, P. C. Keng, Y. Yu and C. Y. Li, Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status. J. Biol. Chem. 270, 11033-11036 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 11033-11036
    • Little, J.B.1    Nagasawa, H.2    Keng, P.C.3    Yu, Y.4    Li, C.Y.5
  • 32
    • 0025341341 scopus 로고
    • Expression of mdr1 and mdr3 multidrug-resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporine
    • H. Herweijer, P. Sonneveld, F. Baas and K. Nooter, Expression of mdr1 and mdr3 multidrug-resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporine. J. Natl. Cancer Inst. 82, 1133-1140 (1990).
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 1133-1140
    • Herweijer, H.1    Sonneveld, P.2    Baas, F.3    Nooter, K.4
  • 33
    • 4444275386 scopus 로고    scopus 로고
    • Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells
    • Z. Duan, K. A. Brakora and M. V. Seiden, Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells. Mol. Cancer Ther. 3, 833-838 (2004).
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 833-838
    • Duan, Z.1    Brakora, K.A.2    Seiden, M.V.3
  • 34
    • 0034604707 scopus 로고    scopus 로고
    • MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping
    • A. J. Smith, A. van Helvoort, G. van Meer, K. Szabo, E. Welker, G. Szakacs, A. Varadi, B. Sarkadi and P. Borst, MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping. J. Biol. Chem. 275, 23530-23539 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 23530-23539
    • Smith, A.J.1    Van Helvoort, A.2    Van Meer, G.3    Szabo, K.4    Welker, E.5    Szakacs, G.6    Varadi, A.7    Sarkadi, B.8    Borst, P.9
  • 36
    • 0023802913 scopus 로고
    • Ex vivo treatment of murine splenocyte-supplemented bone marrow inocula with mafosfamide prior to allogeneic transplantation in an attempt to prevent lethal graft-versus-host disease without compromising engraftment
    • F. R. Kohn and N. E. Sladek, Ex vivo treatment of murine splenocyte-supplemented bone marrow inocula with mafosfamide prior to allogeneic transplantation in an attempt to prevent lethal graft-versus-host disease without compromising engraftment. Immunopharmacol. Immunotoxicol. 10, 387-398 (1988).
    • (1988) Immunopharmacol. Immunotoxicol. , vol.10 , pp. 387-398
    • Kohn, F.R.1    Sladek, N.E.2
  • 37
    • 0036870597 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in classical and atypical multidrug-resistant gastric carcinoma cells
    • A. Ludwig, M. Dietel and H. Lage, Identification of differentially expressed genes in classical and atypical multidrug-resistant gastric carcinoma cells. Anticancer Res. 22, 3213-3221 (2002).
    • (2002) Anticancer Res. , vol.22 , pp. 3213-3221
    • Ludwig, A.1    Dietel, M.2    Lage, H.3
  • 38
    • 0035913332 scopus 로고    scopus 로고
    • An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming
    • J. E. Richmond, R. M. Weimer and E. M. Jorgensen, An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming. Nature 412, 338-341 (2001).
    • (2001) Nature , vol.412 , pp. 338-341
    • Richmond, J.E.1    Weimer, R.M.2    Jorgensen, E.M.3
  • 39
    • 0037008753 scopus 로고    scopus 로고
    • Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly
    • S. J. Scales, B. A. Hesser, E. S. Masuda and R. H. Scheller, Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly. J. Biol. Chem. 277, 28271-28279 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 28271-28279
    • Scales, S.J.1    Hesser, B.A.2    Masuda, E.S.3    Scheller, R.H.4
  • 40
    • 0032190057 scopus 로고    scopus 로고
    • p53 is involved in but not required for ionizing radiation-induced caspase-3 activation and apoptosis in human lymphoblast cell lines
    • Y. Yu and J. B. Little, p53 is involved in but not required for ionizing radiation-induced caspase-3 activation and apoptosis in human lymphoblast cell lines. Cancer Res. 58, 4277-4281 (1998).
    • (1998) Cancer Res. , vol.58 , pp. 4277-4281
    • Yu, Y.1    Little, J.B.2
  • 41
    • 0034657818 scopus 로고    scopus 로고
    • Effects of the multidrug transporter P-glycoprotein on cellular responses to ionizing radiation
    • A. C. Ruth and I. B. Roninson, Effects of the multidrug transporter P-glycoprotein on cellular responses to ionizing radiation. Cancer Res. 60, 2576-2578 (2000).
    • (2000) Cancer Res. , vol.60 , pp. 2576-2578
    • Ruth, A.C.1    Roninson, I.B.2
  • 42
    • 0033591008 scopus 로고    scopus 로고
    • Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site
    • K. Nakatani, H. Sakaue, D. A. Thompson, R. J. Weigel and R. A. Roth, Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site. Biochem. Biophys. Res. Commun. 257, 906-910 (1999).
    • (1999) Biochem. Biophys. Res. Commun. , vol.257 , pp. 906-910
    • Nakatani, K.1    Sakaue, H.2    Thompson, D.A.3    Weigel, R.J.4    Roth, R.A.5
  • 44
    • 2342565881 scopus 로고    scopus 로고
    • Advances in protein kinase B signalling: AKTion on multiple fronts
    • D. P. Brazil, Z. Z. Yang and B. A. Hemmings, Advances in protein kinase B signalling: AKTion on multiple fronts. Trends Biochem. Sci. 29, 233-242 (2004).
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 233-242
    • Brazil, D.P.1    Yang, Z.Z.2    Hemmings, B.A.3
  • 46
    • 0036896782 scopus 로고    scopus 로고
    • Suppression of apoptosis and clonogenic survival in irradiated human lymphoblasts with different TP53 status
    • J. Schafer, J. Bachtler, A. Engling, J. B. Little, K. J. Weber and F. Wenz, Suppression of apoptosis and clonogenic survival in irradiated human lymphoblasts with different TP53 status. Radiat. Res. 158, 699-706 (2002).
    • (2002) Radiat. Res. , vol.158 , pp. 699-706
    • Schafer, J.1    Bachtler, J.2    Engling, A.3    Little, J.B.4    Weber, K.J.5    Wenz, F.6
  • 48
    • 0032785021 scopus 로고    scopus 로고
    • Caspase structure, proteolytic substrates, and function during apoptotic cell death
    • D. W. Nicholson, Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ. 6, 1028-1042 (1999).
    • (1999) Cell Death Differ. , vol.6 , pp. 1028-1042
    • Nicholson, D.W.1
  • 49
    • 0035937797 scopus 로고    scopus 로고
    • A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis
    • Z. L. Chu, F. Pio, Z. Xie, K. Welsh, M. Krajewska, S. Krajewski, A. Godzik and J. C. Reed, A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis. J. Biol. Chem. 276, 9239-9245 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 9239-9245
    • Chu, Z.L.1    Pio, F.2    Xie, Z.3    Welsh, K.4    Krajewska, M.5    Krajewski, S.6    Godzik, A.7    Reed, J.C.8
  • 50
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • L. Agostini, F. Martinon, K. Burns, M. F. McDermott, P. N. Hawkins and J. Tschopp, NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20, 319-325 (2004).
    • (2004) Immunity , vol.20 , pp. 319-325
    • Agostini, L.1    Martinon, F.2    Burns, K.3    McDermott, M.F.4    Hawkins, P.N.5    Tschopp, J.6
  • 51
    • 10644258637 scopus 로고    scopus 로고
    • PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-κB and caspase-1 activation in macrophages
    • J. M. Bruey, N. Bruey-Sedano, R. Newman, S. Chandler, C. Stehlik and J. C. Reed, PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-κB and caspase-1 activation in macrophages. J. Biol. Chem. 279, 51897-51907 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 51897-51907
    • Bruey, J.M.1    Bruey-Sedano, N.2    Newman, R.3    Chandler, S.4    Stehlik, C.5    Reed, J.C.6
  • 53
    • 0028984948 scopus 로고
    • Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
    • P. Li, H. Allen, S. Banerjee, S. Franklin, L. Herzog, C. Johnston, J. McDowell, M. Paskind, L. Rodman and J. Salfeld, Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 80, 401-411 (1995).
    • (1995) Cell , vol.80 , pp. 401-411
    • Li, P.1    Allen, H.2    Banerjee, S.3    Franklin, S.4    Herzog, L.5    Johnston, C.6    McDowell, J.7    Paskind, M.8    Rodman, L.9    Salfeld, J.10
  • 54
    • 0037021415 scopus 로고    scopus 로고
    • A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis
    • S. Gupta, V. Radha, C. Sudhakar and G. Swarup, A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis. FEBS Lett. 532, 61-66 (2002).
    • (2002) FEBS Lett. , vol.532 , pp. 61-66
    • Gupta, S.1    Radha, V.2    Sudhakar, C.3    Swarup, G.4
  • 55
  • 56
    • 13244252271 scopus 로고    scopus 로고
    • Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis
    • S. Sadasivam, S. Gupta, V. Radha, K. Batta, T. K. Kundu and G. Swarup, Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis. Oncogene 24, 627-636 (2005).
    • (2005) Oncogene , vol.24 , pp. 627-636
    • Sadasivam, S.1    Gupta, S.2    Radha, V.3    Batta, K.4    Kundu, T.K.5    Swarup, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.