-
1
-
-
0030871780
-
Apoptosis: An indicator of radiosensitivity in vitro?
-
P. L. Olive and R. E. Durand, Apoptosis: An indicator of radiosensitivity in vitro? Int. J. Radiat. Biol. 71, 695-707 (1997).
-
(1997)
Int. J. Radiat. Biol.
, vol.71
, pp. 695-707
-
-
Olive, P.L.1
Durand, R.E.2
-
2
-
-
0030875480
-
Apoptosis and mitotic cell death: Their relative contributions to normal-tissue and tumour radiation response
-
J. H. Hendry and C. M. West, Apoptosis and mitotic cell death: Their relative contributions to normal-tissue and tumour radiation response. Int. J. Radiat. Biol. 71, 709-719 (1997).
-
(1997)
Int. J. Radiat. Biol.
, vol.71
, pp. 709-719
-
-
Hendry, J.H.1
West, C.M.2
-
3
-
-
0033118475
-
Apoptosis, p53, and tumor cell sensitivity to anticancer agents
-
J. M. Brown and B. G. Wouters, Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res. 59, 1391-1399 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 1391-1399
-
-
Brown, J.M.1
Wouters, B.G.2
-
5
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
S. W. Lowe, H. E. Ruley, T. Jacks and D. E. Housman, p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74, 957-967 (1993).
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
6
-
-
0027948119
-
p53 status, DNA double-strand break repair proficiency, and radiation response of mouse lymphoid and myeloid cell lines
-
I. R. Radford, p53 status, DNA double-strand break repair proficiency, and radiation response of mouse lymphoid and myeloid cell lines. Int. J. Radiat. Biol. 66, 557-560 (1994).
-
(1994)
Int. J. Radiat. Biol.
, vol.66
, pp. 557-560
-
-
Radford, I.R.1
-
7
-
-
0028181452
-
Radiation response of mouse lymphoid and myeloid cell lines. Part III. Different signals can lead to apoptosis and may influence sensitivity to killing by DNA doublestrand breakage
-
I. R. Radford and T. K. Murphy, Radiation response of mouse lymphoid and myeloid cell lines. Part III. Different signals can lead to apoptosis and may influence sensitivity to killing by DNA doublestrand breakage. Int. J. Radiat. Biol. 65, 229-239 (1994).
-
(1994)
Int. J. Radiat. Biol.
, vol.65
, pp. 229-239
-
-
Radford, I.R.1
Murphy, T.K.2
-
8
-
-
0026649127
-
Radiation-induced apoptosis: Its role in a MADCaT (mitosis-apoptosis-differentiation-calcium toxicity) scheme of cytotoxicity mechanisms
-
D. J. Allan, Radiation-induced apoptosis: Its role in a MADCaT (mitosis-apoptosis-differentiation-calcium toxicity) scheme of cytotoxicity mechanisms. Int. J. Radiat. Biol. 62, 145-152 (1992).
-
(1992)
Int. J. Radiat. Biol.
, vol.62
, pp. 145-152
-
-
Allan, D.J.1
-
9
-
-
0027761455
-
Biochemical modulation of radiation-induced apoptosis in murine lymphoma cells
-
R. E. Meyn, L. C. Stephens, D. W. Voehringer, M. D. Story, N. Mirkovic and L. Milas, Biochemical modulation of radiation-induced apoptosis in murine lymphoma cells. Radiat. Res. 136, 327-334 (1993).
-
(1993)
Radiat. Res.
, vol.136
, pp. 327-334
-
-
Meyn, R.E.1
Stephens, L.C.2
Voehringer, D.W.3
Story, M.D.4
Mirkovic, N.5
Milas, L.6
-
10
-
-
0025894713
-
p53 mutations in human cancers
-
M. Hollstein, D. Sidransky, B. Vogelstein and C. C. Harris, p53 mutations in human cancers. Science 253, 49-53 (1991).
-
(1991)
Science
, vol.253
, pp. 49-53
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.C.4
-
12
-
-
0032126541
-
Explaining differences in sensitivity to killing by ionizing radiation between human lymphoid cell lines
-
D. R. Aldridge and I. R. Radford, Explaining differences in sensitivity to killing by ionizing radiation between human lymphoid cell lines. Cancer Res. 58, 2817-2824 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 2817-2824
-
-
Aldridge, D.R.1
Radford, I.R.2
-
13
-
-
0018075843
-
Radiation-induced cellular reproductive death and chromosome aberrations
-
J. S. Bedford, J. B. Mitchell, H. G. Griggs and M. A. Bender, Radiation-induced cellular reproductive death and chromosome aberrations. Radiat. Res. 76, 573-586 (1978).
-
(1978)
Radiat. Res.
, vol.76
, pp. 573-586
-
-
Bedford, J.S.1
Mitchell, J.B.2
Griggs, H.G.3
Bender, M.A.4
-
14
-
-
0031742958
-
The role of DNA single- and double-strand breaks in cell killing by ionizing radiation
-
P. L. Olive, The role of DNA single- and double-strand breaks in cell killing by ionizing radiation. Radiat. Res. 150 (Suppl.), S42-S51 (1998).
-
(1998)
Radiat. Res.
, vol.150
, Issue.SUPPL.
-
-
Olive, P.L.1
-
15
-
-
0036244556
-
P53, apoptosis and radiosensitivity - Experimental and clinical data
-
K. J. Weber and F. Wenz, P53, apoptosis and radiosensitivity - Experimental and clinical data. Onkologie 25, 136-141 (2002).
-
(2002)
Onkologie
, vol.25
, pp. 136-141
-
-
Weber, K.J.1
Wenz, F.2
-
16
-
-
0014333021
-
Human lymphoblastoid lines from lymph node and spleen
-
J. A. Levy, M. Virolainen and V. Defendi, Human lymphoblastoid lines from lymph node and spleen. Cancer 22, 517-524 (1968).
-
(1968)
Cancer
, vol.22
, pp. 517-524
-
-
Levy, J.A.1
Virolainen, M.2
Defendi, V.3
-
17
-
-
0025945665
-
A system for assaying homologous recombination at the endogenous human thymidine kinase gene
-
M. B. Benjamin, H. Potter, D. W. Yandell and J. B. Little, A system for assaying homologous recombination at the endogenous human thymidine kinase gene. Proc. Natl. Acad. Sci. USA 88, 6652-6656 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 6652-6656
-
-
Benjamin, M.B.1
Potter, H.2
Yandell, D.W.3
Little, J.B.4
-
19
-
-
0030915269
-
Abrogation of p53 function by HPV16 E6 gene delays apoptosis and enhances mutagenesis but does not alter radiosensitivity in TK6 human lymphoblast cells
-
Y. Yu, C. Y. Li and J. B. Little, Abrogation of p53 function by HPV16 E6 gene delays apoptosis and enhances mutagenesis but does not alter radiosensitivity in TK6 human lymphoblast cells. Oncogene 14, 1661-1667 (1997).
-
(1997)
Oncogene
, vol.14
, pp. 1661-1667
-
-
Yu, Y.1
Li, C.Y.2
Little, J.B.3
-
20
-
-
0025639158
-
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
-
M. Scheffner, B. A. Werness, J. M. Huibregtse, A. J. Levine and P M. Howley. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63, 1129-1136 (1990).
-
(1990)
Cell
, vol.63
, pp. 1129-1136
-
-
Scheffner, M.1
Werness, B.A.2
Huibregtse, J.M.3
Levine, A.J.4
Howley, P.M.5
-
21
-
-
0030852882
-
Lack of uncoupling of S phase and mitosis after irradiation in p53-human lymphoblast cell lines
-
F. Wenz, Y. Yu, H. Nagasawa, A. C. Imrich, P. Keng and J. B. Little, Lack of uncoupling of S phase and mitosis after irradiation in p53-human lymphoblast cell lines. Radiat. Res. 148, 129-134 (1997).
-
(1997)
Radiat. Res.
, vol.148
, pp. 129-134
-
-
Wenz, F.1
Yu, Y.2
Nagasawa, H.3
Imrich, A.C.4
Keng, P.5
Little, J.B.6
-
22
-
-
0028980555
-
Different sensitivity to cell killing and chromosome mutation induction by gamma rays in two human lymphoblastoid cell lines derived from a single donor: Possible role of apoptosis
-
J. L. Schwartz, R. Jordan, B. A. Sedita, M. J. Swenningson, J. P. Banath and P. L. Olive, Different sensitivity to cell killing and chromosome mutation induction by gamma rays in two human lymphoblastoid cell lines derived from a single donor: Possible role of apoptosis. Mutagenesis 10, 227-233 (1995).
-
(1995)
Mutagenesis
, vol.10
, pp. 227-233
-
-
Schwartz, J.L.1
Jordan, R.2
Sedita, B.A.3
Swenningson, M.J.4
Banath, J.P.5
Olive, P.L.6
-
23
-
-
0027423615
-
Radiation-induced apoptosis measured in TK 6 human B lymphoblast cells using the comet assay
-
P. L. Olive, G. Frazer and J. P. Banath, Radiation-induced apoptosis measured in TK6 human B lymphoblast cells using the comet assay. Radiat. Res. 136, 130-136 (1993).
-
(1993)
Radiat. Res.
, vol.136
, pp. 130-136
-
-
Olive, P.L.1
Frazer, G.2
Banath, J.P.3
-
24
-
-
0028986587
-
The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status
-
W. Zhen, C. M. Denault, K. Loviscek, S. Walter, L. Geng and A. T. Vaughan, The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status. Mutat. Res. 346, 85-92 (1995).
-
(1995)
Mutat. Res.
, vol.346
, pp. 85-92
-
-
Zhen, W.1
Denault, C.M.2
Loviscek, K.3
Walter, S.4
Geng, L.5
Vaughan, A.T.6
-
25
-
-
0031409634
-
Selective elimination of human lymphoid cells with unstable chromosome aberrations by p53-dependent apoptosis
-
J. L. Schwartz and R. Jordan, Selective elimination of human lymphoid cells with unstable chromosome aberrations by p53-dependent apoptosis. Carcinogenesis 18, 201-205 (1997).
-
(1997)
Carcinogenesis
, vol.18
, pp. 201-205
-
-
Schwartz, J.L.1
Jordan, R.2
-
26
-
-
0032190057
-
p53 is involved in but not required for ionizing radiation-induced caspase-3 activation and apoptosis in human lymphoblast cell lines
-
Y. Yu and J. B. Little, p53 is involved in but not required for ionizing radiation-induced caspase-3 activation and apoptosis in human lymphoblast cell lines. Cancer Res. 58, 4277-4281 (1998).
-
(1998)
Cancer Res.
, vol.58
, pp. 4277-4281
-
-
Yu, Y.1
Little, J.B.2
-
27
-
-
0031983319
-
The response of proliferating cell nuclear antigen to ionizing radiation in human lymphoblastoid cell lines is dependent on p 53
-
F. Wenz, E. I. Azzam and J. B. Little, The response of proliferating cell nuclear antigen to ionizing radiation in human lymphoblastoid cell lines is dependent on p53. Radiat. Res. 149, 32-40 (1998).
-
(1998)
Radiat. Res.
, vol.149
, pp. 32-40
-
-
Wenz, F.1
Azzam, E.I.2
Little, J.B.3
-
28
-
-
0025726216
-
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
-
I. Nicoletti, G. Migliorati, M. C. Pagliacci, F. Grignani and C. Riccardi, A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139, 271-279 (1991).
-
(1991)
J. Immunol. Methods
, vol.139
, pp. 271-279
-
-
Nicoletti, I.1
Migliorati, G.2
Pagliacci, M.C.3
Grignani, F.4
Riccardi, C.5
-
29
-
-
0023919963
-
A simple technique for quantitation of low levels of DNA damage in individual cells
-
N. P. Singh, M. T. McCoy, R. R. Tice and E. L. Schneider, A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175, 184-191 (1988).
-
(1988)
Exp. Cell Res.
, vol.175
, pp. 184-191
-
-
Singh, N.P.1
McCoy, M.T.2
Tice, R.R.3
Schneider, E.L.4
-
31
-
-
0029045164
-
The comet moment as a measure of DNA damage in the comet assay
-
C. R. Kent, J. J. Eady, G. M. Ross and G. G. Steel, The comet moment as a measure of DNA damage in the comet assay. Int. J. Radiat. Biol. 67, 655-660 (1995).
-
(1995)
Int. J. Radiat. Biol.
, vol.67
, pp. 655-660
-
-
Kent, C.R.1
Eady, J.J.2
Ross, G.M.3
Steel, G.G.4
-
32
-
-
0027219914
-
Lethality of heavy ion-induced DNA double-strand breaks in mammalian cells
-
K. J. Weber and M. Flentje, Lethality of heavy ion-induced DNA double-strand breaks in mammalian cells. Int. J. Radiat. Biol. 64, 169-178 (1993).
-
(1993)
Int. J. Radiat. Biol.
, vol.64
, pp. 169-178
-
-
Weber, K.J.1
Flentje, M.2
-
33
-
-
0035099457
-
Overexpression of the DNA-binding domain of poly(ADP-ribose)polymerase inhibits rejoining of ionizing radiation-induced DNA double-strand breaks
-
V. Rudat, N. Bachmann, J-H. Kuepper and K. J. Weber, Overexpression of the DNA-binding domain of poly(ADP-ribose)polymerase inhibits rejoining of ionizing radiation-induced DNA double-strand breaks. Int. J. Radiat. Biol. 77, 303-307 (2001).
-
(2001)
Int. J. Radiat. Biol.
, vol.77
, pp. 303-307
-
-
Rudat, V.1
Bachmann, N.2
Kuepper, J.-H.3
Weber, K.J.4
-
34
-
-
0033535527
-
Induction of the p53-target gene GADD45 in HPV-positive cancer cells
-
K. Butz, N. Whitaker, C. Denk, A. Ullmann, C. Geisen and F. HoppeSeyler, Induction of the p53-target gene GADD45 in HPV-positive cancer cells. Oncogene 18, 2381-2386 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 2381-2386
-
-
Butz, K.1
Whitaker, N.2
Denk, C.3
Ullmann, A.4
Geisen, C.5
HoppeSeyler, F.6
-
35
-
-
0027210981
-
Gain of function mutations in p53
-
D. Dittmer, S. Pati, G. Zambetti, S. Chu, A. K. Teresky, M. Moore, C. Finlay and A. J. Levine, Gain of function mutations in p53. Nat. Genet. 4, 42-46 (1993).
-
(1993)
Nat. Genet.
, vol.4
, pp. 42-46
-
-
Dittmer, D.1
Pati, S.2
Zambetti, G.3
Chu, S.4
Teresky, A.K.5
Moore, M.6
Finlay, C.7
Levine, A.J.8
-
36
-
-
0034671945
-
Oncogenic mutations of the p53 tumor suppressor: The demons of the guardian of the genome
-
A. Sigal and V. Rotter, Oncogenic mutations of the p53 tumor suppressor: The demons of the guardian of the genome. Cancer Res. 60, 6788-6793 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 6788-6793
-
-
Sigal, A.1
Rotter, V.2
-
37
-
-
0033958086
-
Multiple physiological functions for multidrug transporter P-glycoprotein?
-
R. W. Johnstone, A. A. Ruefli and M. J. Smyth, Multiple physiological functions for multidrug transporter P-glycoprotein? Trends Biochem. Sci. 25, 1-6 (2000).
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 1-6
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Smyth, M.J.3
-
38
-
-
0034657818
-
Effects of the multidrug transporter p-glycoprotein on cellular response to ionizing radiation
-
A. C. Ruth and I. G. Roninson, Effects of the multidrug transporter p-glycoprotein on cellular response to ionizing radiation. Cancer Res. 60, 2576-2578 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 2576-2578
-
-
Ruth, A.C.1
Roninson, I.G.2
-
39
-
-
0000727744
-
Genetherapeutic and pharmacological suppression of radiation-induced apoptosis
-
abstract
-
K. J. Weber, A. Engling, J. Schaefer, S. Fruehauf and F. Wenz, Genetherapeutic and pharmacological suppression of radiation-induced apoptosis. Int. J. Radiat. Oncol. Biol. Phys. 48 (Suppl. 1), 279 (2000). [abstract]
-
(2000)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.48
, Issue.SUPPL. 1
, pp. 279
-
-
Weber, K.J.1
Engling, A.2
Schaefer, J.3
Fruehauf, S.4
Wenz, F.5
-
40
-
-
0033038562
-
Radiation induced chromosome aberrations and clonogenic survival in human lymphoblastoid cell lines with different p53 status
-
C. Geiger, K. J. Weber and F. Wenz, Radiation induced chromosome aberrations and clonogenic survival in human lymphoblastoid cell lines with different p53 status. Strahlenther. Onkol. 175, 289-292 (1999).
-
(1999)
Strahlenther. Onkol.
, vol.175
, pp. 289-292
-
-
Geiger, C.1
Weber, K.J.2
Wenz, F.3
-
41
-
-
0030665150
-
The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells
-
R. Y. Poon, M. S. Chau, K. Yamashita and T. Hunter, The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells. Cancer Res. 57, 5168-5178 (1997).
-
(1997)
Cancer Res.
, vol.57
, pp. 5168-5178
-
-
Poon, R.Y.1
Chau, M.S.2
Yamashita, K.3
Hunter, T.4
-
42
-
-
0033533725
-
Caffeine inhibits the checkpoint kinase ATM
-
A. Blasina, B. D. Price, G. A. Turenne and C. H. McGowan, Caffeine inhibits the checkpoint kinase ATM. Curr. Biol. 9, 1135-1138 (1999).
-
(1999)
Curr. Biol.
, vol.9
, pp. 1135-1138
-
-
Blasina, A.1
Price, B.D.2
Turenne, G.A.3
McGowan, C.H.4
-
43
-
-
0034616329
-
2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity
-
2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity. J. Biol. Chem. 275, 10342-10348 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10342-10348
-
-
Zhou, B.B.1
Chaturvedi, P.2
Spring, K.3
Scott, S.P.4
Johanson, R.A.5
Mishra, R.6
Mattern, M.R.7
Winkler, J.D.8
Khanna, K.K.9
-
45
-
-
0028921082
-
Effect of caffeine on radiation-induced apoptosis in TK6 cells
-
W. Zhen and A. T. Vaughan, Effect of caffeine on radiation-induced apoptosis in TK6 cells. Radiat. Res. 141, 170-175 (1995).
-
(1995)
Radiat. Res.
, vol.141
, pp. 170-175
-
-
Zhen, W.1
Vaughan, A.T.2
-
46
-
-
0034629072
-
DNA damage-induced activation of p53 by the checkpoint kinase Chk2
-
A. Hirao, Y-Y. Kong, S. Matsuoka, A. Wakeham, J. Ruland, H. Yoshida, D. Liu, S. J. Elledge and T. W. Mak, DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science 287, 1824-1827 (2000).
-
(2000)
Science
, vol.287
, pp. 1824-1827
-
-
Hirao, A.1
Kong, Y.-Y.2
Matsuoka, S.3
Wakeham, A.4
Ruland, J.5
Yoshida, H.6
Liu, D.7
Elledge, S.J.8
Mak, T.W.9
-
48
-
-
0028936626
-
2 delay
-
2 delay. Cancer Res. 55, 1643-1648 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 1643-1648
-
-
Powell, S.N.1
DeFrank, J.S.2
Connell, P.3
Eogan, M.4
Preffer, F.5
Dombkowski, D.6
Tang, W.7
Friend, S.8
-
49
-
-
0031016093
-
The tumor suppressor p53 modifies mutational processes in a human lymphoblastoid cell line
-
F. Xia and H. L. Liber, The tumor suppressor p53 modifies mutational processes in a human lymphoblastoid cell line. Mutat. Res. 373, 87-97 (1997).
-
(1997)
Mutat. Res.
, vol.373
, pp. 87-97
-
-
Xia, F.1
Liber, H.L.2
-
50
-
-
0035152978
-
TP53-dependent chromosome instability is associated with transient reductions in telomere length in immortal telomerase-positive cell lines
-
J. L. Schwartz, R. Jordan, H. Liber, J. P. Murnane and H. H. Evans, TP53-dependent chromosome instability is associated with transient reductions in telomere length in immortal telomerase-positive cell lines. Genes Chromosomes Cancer 30, 236-244 (2001).
-
(2001)
Genes Chromosomes Cancer
, vol.30
, pp. 236-244
-
-
Schwartz, J.L.1
Jordan, R.2
Liber, H.3
Murnane, J.P.4
Evans, H.H.5
|