Improved post-transcriptional processing of an MDR1 retrovirus elevates expression of multidrug resistance in primary human hematopoietic cells

Gene Therapy

Volumn 8, Issue 3, 2001, Pages 239-246

  Knipper, R ^a   Kuehlcke, K ^a   Schiedlmeier, B ^b   Hildinger, M ^b   Lindemann, C ^a   Schilz, A J ^a   Fauser, A A ^a   Fruehauf, S ^c   Zeller, W J ^d   Ostertag, W ^b   Eckert, H G ^a   Baum, C ^b,e  

^a BIONTECH AG   (Germany)

^b LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Hematopoiesis; Multidrug resistance 1; Retroviral vector; RNA processing

Indexed keywords

CD34 ANTIGEN; CD45 ANTIGEN; COLCHICINE; COMPLEMENTARY DNA; CYCLOSPORIN A; CYTOTOXIC AGENT; GLYCOPROTEIN P; GRANULOCYTE COLONY STIMULATING FACTOR; HOE 33342; MULTIDRUG RESISTANCE PROTEIN; RHODAMINE 123; VIRUS DNA; VIRUS PROTEIN; VIRUS RNA; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; COLONY FORMING CELL; CONTROLLED STUDY; DNA PACKAGING; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GENE TRANSFER; GENETIC ANALYSIS; GENETIC CODE; GENETIC TRANSDUCTION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; MARKER GENE; MOUSE; MOUSE STRAIN; MULTIDRUG RESISTANCE; NONHUMAN; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PROCESSING; PROVIRUS; RETROVIRUS; SEQUENCE ANALYSIS; START CODON; VIRUS GENE;

ANIMALS; ANTINEOPLASTIC AGENTS; COLONY-FORMING UNITS ASSAY; DRUG RESISTANCE, MULTIPLE; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; MICE, INBRED NOD; MICE, SCID; P-GLYCOPROTEIN; RETROVIRIDAE; RNA PROCESSING, POST-TRANSCRIPTIONAL; TRANSDUCTION, GENETIC;

ANIMALIA; DNA VIRUSES; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 17744372078     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301384     Document Type: Article

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