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Volumn 2, Issue 6, 2000, Pages 609-618

MDR1 gene expression in NOD/SCID repopulating cells after retroviral gene transfer under clinically relevant conditions

Author keywords

CD34+ cells; Gene therapy; MDR1; Mobilized peripheral blood; NOD SCID; Retroviral gene transfer

Indexed keywords

ALOCASIA MACRORRHIZOS; GIBBON APE LEUKEMIA VIRUS; HYLOBATES SP.;

EID: 0034571820     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2000.0216     Document Type: Article
Times cited : (35)

References (77)
  • 1
    • 0025279872 scopus 로고
    • Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
    • Miller, D. G., Adam, M. A., and Miller, A. D. (1990). Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol. Cell. Biol. 10: 4239-4242.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 4239-4242
    • Miller, D.G.1    Adam, M.A.2    Miller, A.D.3
  • 2
    • 0028055281 scopus 로고
    • Passage through mitosis is required for oncoretroviruses but not for human immunodeficiency virus
    • Lewis, P. F., and Emerman, M. (1994). Passage through mitosis is required for oncoretroviruses but not for human immunodeficiency virus. J. Virol. 68: 510-516.
    • (1994) J. Virol. , vol.68 , pp. 510-516
    • Lewis, P.F.1    Emerman, M.2
  • 3
    • 0030951437 scopus 로고    scopus 로고
    • The biology and clinical uses of blood stem cells
    • To, L. B., Haylock, D. N., Simmons, P. J., and Juttner, C. A. (1997). The biology and clinical uses of blood stem cells. Blood 89: 2233-2258.
    • (1997) Blood , vol.89 , pp. 2233-2258
    • To, L.B.1    Haylock, D.N.2    Simmons, P.J.3    Juttner, C.A.4
  • 4
    • 0029008335 scopus 로고
    • Hematopoietic rescue after high-dose chemotherapy using autologous peripheral-blood progenitor cells or bone marrow: A randomized comparison
    • Beyer, J., et al. (1995). Hematopoietic rescue after high-dose chemotherapy using autologous peripheral-blood progenitor cells or bone marrow: A randomized comparison. J. Clin. Oncol. 13: 1328-1335.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 1328-1335
    • Beyer, J.1
  • 5
    • 0027443191 scopus 로고
    • Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients
    • Brenner, M. K., et al. (1993). Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients. Lancet 342: 1134-1137.
    • (1993) Lancet , vol.342 , pp. 1134-1137
    • Brenner, M.K.1
  • 6
    • 85041132416 scopus 로고
    • + cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow transplantation in CML
    • + cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow transplantation in CML. Blood 83: 3068-3076.
    • (1994) Blood , vol.83 , pp. 3068-3076
    • Deisseroth, A.B.1
  • 7
    • 0028864561 scopus 로고
    • Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency
    • Kohn, D. B., et al. (1995). Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Nat. Med. 1: 1017-1023.
    • (1995) Nat. Med. , vol.1 , pp. 1017-1023
    • Kohn, D.B.1
  • 8
    • 0028789792 scopus 로고
    • Gene therapy in peripheral blood lymphocytes and bone marrow for ADA-immunodeficient patients
    • Bordignon, C., et al. (1995). Gene therapy in peripheral blood lymphocytes and bone marrow for ADA-immunodeficient patients. Science 270: 470-475.
    • (1995) Science , vol.270 , pp. 470-475
    • Bordignon, C.1
  • 9
    • 0029068059 scopus 로고
    • Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation
    • Dunbar, C., et al. (1995). Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation. Blood 85: 3048-3057.
    • (1995) Blood , vol.85 , pp. 3048-3057
    • Dunbar, C.1
  • 10
    • 12644293807 scopus 로고    scopus 로고
    • Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease
    • Malech, H. L., et al. (1997). Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease. Proc. Natl. Acad. Sci. USA 94: 12133-12138.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12133-12138
    • Malech, H.L.1
  • 11
    • 0030965964 scopus 로고    scopus 로고
    • + cells for six hours without growth factors or on autologous stroma does not improve marking efficiency assessed in vivo
    • + cells for six hours without growth factors or on autologous stroma does not improve marking efficiency assessed in vivo. Blood 89: 4040-4046.
    • (1997) Blood , vol.89 , pp. 4040-4046
    • Emmons, R.V.B.1
  • 12
    • 0031972859 scopus 로고    scopus 로고
    • Phase I clinical trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation
    • Hesdorffer, C., et al. (1998). Phase I clinical trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation. J. Clin. Oncol. 16: 165-172.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 165-172
    • Hesdorffer, C.1
  • 13
    • 0030448053 scopus 로고    scopus 로고
    • Results of MDR-1 vector modification trial indicate that granulocyte/macrophage colony-forming unit cells do not contribute to posttransplant hematopoietic recovery following intensive systemic therapy
    • Hanania, E. G., et al. (1996). Results of MDR-1 vector modification trial indicate that granulocyte/macrophage colony-forming unit cells do not contribute to posttransplant hematopoietic recovery following intensive systemic therapy. Proc. Natl. Acad. Sci. USA 93: 15346-15351.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 15346-15351
    • Hanania, E.G.1
  • 14
    • 0033168346 scopus 로고    scopus 로고
    • Engraftment of MDR1 and NeoR gene-transduced hematopoietic cells after breast cancer chemotherapy
    • Moscow, J. A., et al. (1999). Engraftment of MDR1 and NeoR gene-transduced hematopoietic cells after breast cancer chemotherapy. Blood 94: 52-61.
    • (1999) Blood , vol.94 , pp. 52-61
    • Moscow, J.A.1
  • 15
    • 0032809319 scopus 로고    scopus 로고
    • Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients
    • Cowan, K. H., et al. (1999). Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients. Clin. Cancer Res. 5: 1619-1628.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1619-1628
    • Cowan, K.H.1
  • 16
    • 0027945417 scopus 로고
    • Increased gene transfer into human hematopoietic progenitor cells by extended in vitro exposure to a pseudotyped retroviral vector
    • von Kalle, C., et al. (1994). Increased gene transfer into human hematopoietic progenitor cells by extended in vitro exposure to a pseudotyped retroviral vector. Blood 84: 2890-2897.
    • (1994) Blood , vol.84 , pp. 2890-2897
    • Von Kalle, C.1
  • 17
    • 0029118325 scopus 로고
    • High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes
    • Bunnell, B. A., Muul, L. M., Donahue, R. E., Blaese, R. M., and Morgan, R. A. (1995). High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes. Proc. Natl. Acad. Sci. USA 92: 7739-7743.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7739-7743
    • Bunnell, B.A.1    Muul, L.M.2    Donahue, R.E.3    Blaese, R.M.4    Morgan, R.A.5
  • 18
    • 0029096489 scopus 로고
    • Improved transfer of the leukocyte integrin CD18 subunit into hematopoietic cell lines by using retroviral vectors having a gibbon ape leukemia virus envelope
    • Bauer, T. R., Jr., Miller, A. D., and Hickstein, D. D. (1995). Improved transfer of the leukocyte integrin CD18 subunit into hematopoietic cell lines by using retroviral vectors having a gibbon ape leukemia virus envelope. Blood 86: 2379-2387.
    • (1995) Blood , vol.86 , pp. 2379-2387
    • Bauer T.R., Jr.1    Miller, A.D.2    Hickstein, D.D.3
  • 19
    • 0030669613 scopus 로고    scopus 로고
    • Gene transfer into marrow repopulating cells: Comparison between amphotropic and gibbon ape leukemia virus pseudotyped retroviral vectors in a competitive repopulation assay in baboons
    • Kiem, H. P., et al. (1997). Gene transfer into marrow repopulating cells: Comparison between amphotropic and gibbon ape leukemia virus pseudotyped retroviral vectors in a competitive repopulation assay in baboons. Blood 90: 4638-4645.
    • (1997) Blood , vol.90 , pp. 4638-4645
    • Kiem, H.P.1
  • 20
    • 0031581183 scopus 로고    scopus 로고
    • lo human bone marrow cells reselected after long-term exposure to GALV-pseudotyped retroviral vector
    • lo human bone marrow cells reselected after long-term exposure to GALV-pseudotyped retroviral vector. Hum. Gene Ther. 8: 2079-2086.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 2079-2086
    • Glimm, H.1
  • 22
    • 0032548402 scopus 로고    scopus 로고
    • High-level gene transfer to cord blood progenitors using gibbon ape leukemia virus pseudotype retroviral vectors and an improved clinically applicable protocol
    • Movassagh, M., et al. (1998). High-level gene transfer to cord blood progenitors using gibbon ape leukemia virus pseudotype retroviral vectors and an improved clinically applicable protocol. Hum. Gene Ther. 9: 225-234.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 225-234
    • Movassagh, M.1
  • 23
    • 0028176884 scopus 로고
    • Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors
    • Moritz, T., Patel, V. P., and Williams, D. A. (1994). Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors. J. Clin. Invest. 93: 1451-1457.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1451-1457
    • Moritz, T.1    Patel, V.P.2    Williams, D.A.3
  • 24
    • 0029784888 scopus 로고    scopus 로고
    • Fibronectin improves transduction of reconstituting hematopoietic stem cells by retroviral vectors: Evidence for direct viral binding to chymotryptic carboxy-terminal fragments
    • Moritz, T., et al. (1996). Fibronectin improves transduction of reconstituting hematopoietic stem cells by retroviral vectors: Evidence for direct viral binding to chymotryptic carboxy-terminal fragments. Blood 88: 855-862.
    • (1996) Blood , vol.88 , pp. 855-862
    • Moritz, T.1
  • 25
    • 16044366110 scopus 로고    scopus 로고
    • Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells
    • Hanenberg, H., Xiao, X. L., Dilloo, D., Hashinao, K., and Williams, D. A. (1996). Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells. Nat. Med. 2: 876-882.
    • (1996) Nat. Med. , vol.2 , pp. 876-882
    • Hanenberg, H.1    Xiao, X.L.2    Dilloo, D.3    Hashinao, K.4    Williams, D.A.5
  • 26
    • 0028076782 scopus 로고
    • Improved methods of retroviral vector transduction and production for gene therapy
    • Kotani, H., et al. (1994). Improved methods of retroviral vector transduction and production for gene therapy. Hum. Gene Ther. 5: 19-28.
    • (1994) Hum. Gene Ther. , vol.5 , pp. 19-28
    • Kotani, H.1
  • 27
    • 0028203747 scopus 로고
    • Cloning of the human homologue of the murine flt3 ligand: A growth factor for early hematopoietic progenitor cells
    • Lyman, S. D., et al. (1994). Cloning of the human homologue of the murine flt3 ligand: A growth factor for early hematopoietic progenitor cells. Blood 83: 2795-2801.
    • (1994) Blood , vol.83 , pp. 2795-2801
    • Lyman, S.D.1
  • 29
    • 0031019451 scopus 로고    scopus 로고
    • + progenitors to sustain long-term hematopoiesis in immune-deficient mice after ex vivo retroviral-mediated transduction
    • + progenitors to sustain long-term hematopoiesis in immune-deficient mice after ex vivo retroviral-mediated transduction. Blood 89: 446-456.
    • (1997) Blood , vol.89 , pp. 446-456
    • Dao, M.A.1    Hannum, C.H.2    Kohn, D.B.3    Nolta, J.A.4
  • 35
    • 15144342085 scopus 로고    scopus 로고
    • + human blood cells
    • + human blood cells. Stem Cells 15: 347-352.
    • (1997) Stem Cells , vol.15 , pp. 347-352
    • Kim, H.J.1
  • 36
    • 0031000903 scopus 로고    scopus 로고
    • Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood
    • Piacibello, W., et al. (1997). Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood. Blood 8: 2644-2653.
    • (1997) Blood , vol.8 , pp. 2644-2653
    • Piacibello, W.1
  • 37
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman, M. M., and Pastan, I. (1993). Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem. 62: 385-427.
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 38
    • 0025799513 scopus 로고
    • Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells
    • Chaudhary, P. M., and Roninson, I. B. (1991). Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 66: 85-94.
    • (1991) Cell , vol.66 , pp. 85-94
    • Chaudhary, P.M.1    Roninson, I.B.2
  • 39
    • 0026637623 scopus 로고
    • Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of the human MDR1
    • Sorrentino, B. P., Brandt, S. J., Gottesman, M., Pastan, I., Cline, A., and Nienhuis, A. W. (1992). Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of the human MDR1. Science 257: 99-103.
    • (1992) Science , vol.257 , pp. 99-103
    • Sorrentino, B.P.1    Brandt, S.J.2    Gottesman, M.3    Pastan, I.4    Cline, A.5    Nienhuis, A.W.6
  • 40
    • 0027816238 scopus 로고
    • Circumvention of chemotherapy-induced myelosuppression by transfer of the mdr1 gene
    • Boesen, J. J. B., Nooter, K., and Valerio, D. (1994). Circumvention of chemotherapy-induced myelosuppression by transfer of the mdr1 gene. Biotherapy 6: 291-302.
    • (1994) Biotherapy , vol.6 , pp. 291-302
    • Boesen, J.J.B.1    Nooter, K.2    Valerio, D.3
  • 41
    • 0032605117 scopus 로고    scopus 로고
    • Therapeutic strategies involving the multidrug resistance phenotype: The MDR1 gene as target, chemoprotectant, and selectable marker in gene therapy
    • Aran, J. M., Pastan, I., and Gottesman, M. M. (1999). Therapeutic strategies involving the multidrug resistance phenotype: The MDR1 gene as target, chemoprotectant, and selectable marker in gene therapy. Adv. Pharmacol. 46: 1-42.
    • (1999) Adv. Pharmacol. , vol.46 , pp. 1-42
    • Aran, J.M.1    Pastan, I.2    Gottesman, M.M.3
  • 42
    • 0034131481 scopus 로고    scopus 로고
    • Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells
    • Abonour, R., et al. (2000). Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells. Nat. Med. 6: 652-658
    • (2000) Nat. Med. , vol.6 , pp. 652-658
    • Abonour, R.1
  • 43
    • 0028883813 scopus 로고
    • Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells
    • Baum, C., Hegewisch-Becker, S., Eckert, H. G., Stocking, C., and Ostertag, W. (1995). Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells. J. Virol. 69: 7541-7547.
    • (1995) J. Virol. , vol.69 , pp. 7541-7547
    • Baum, C.1    Hegewisch-Becker, S.2    Eckert, H.G.3    Stocking, C.4    Ostertag, W.5
  • 44
    • 0029909913 scopus 로고    scopus 로고
    • High-dose multidrug resistance in primary human hematopoietic progenitor cells transduced with optimized retroviral vectors
    • Eckert, H. G., et al. (1996). High-dose multidrug resistance in primary human hematopoietic progenitor cells transduced with optimized retroviral vectors. Blood 88: 3407-3415.
    • (1996) Blood , vol.88 , pp. 3407-3415
    • Eckert, H.G.1
  • 45
    • 0031739805 scopus 로고    scopus 로고
    • FMEV vectors: Both retroviral long terminal repeat and leader are important for high expression in transduced hematopoietic cells
    • Hildinger, M., Eckert, H.-G., Schilz, A. J., John, J., Ostertag, W., and Baum, C. (1998). FMEV vectors: Both retroviral long terminal repeat and leader are important for high expression in transduced hematopoietic cells. Hum. Gene Ther. 5: 1575-1579.
    • (1998) Hum. Gene Ther. , vol.5 , pp. 1575-1579
    • Hildinger, M.1    Eckert, H.-G.2    Schilz, A.J.3    John, J.4    Ostertag, W.5    Baum, C.6
  • 46
    • 0032804269 scopus 로고    scopus 로고
    • Bicistronic retroviral vectors for combining myeloprotection with cell-surface marking
    • Hildinger, M., et al. (1999). Bicistronic retroviral vectors for combining myeloprotection with cell-surface marking. Gene Ther. 6: 1222-1230.
    • (1999) Gene Ther. , vol.6 , pp. 1222-1230
    • Hildinger, M.1
  • 47
    • 0342470476 scopus 로고    scopus 로고
    • Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice
    • Schiedlmeier, B., Kuhlcke, K., Eckert, H. G., Baum, C., Zeller, W. J., and Fruehauf, S. (2000). Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice. Blood 95: 1237-1248.
    • (2000) Blood , vol.95 , pp. 1237-1248
    • Schiedlmeier, B.1    Kuhlcke, K.2    Eckert, H.G.3    Baum, C.4    Zeller, W.J.5    Fruehauf, S.6
  • 48
    • 0029738440 scopus 로고    scopus 로고
    • Improved vectors for hematopoietic stem cell protection and in vivo selection
    • Baum, C., et al. (1996). Improved vectors for hematopoietic stem cell protection and in vivo selection. J. Hematother. 5: 323-329.
    • (1996) J. Hematother. , vol.5 , pp. 323-329
    • Baum, C.1
  • 49
    • 0028869986 scopus 로고
    • Multiple defects in innate and adaptive immunologic function in NOD/LtSz-Scid mice
    • Shultz, L. D., et al. (1995). Multiple defects in innate and adaptive immunologic function in NOD/LtSz-Scid mice. J. Immunol. 154: 180-191.
    • (1995) J. Immunol. , vol.154 , pp. 180-191
    • Shultz, L.D.1
  • 50
    • 16144365969 scopus 로고    scopus 로고
    • Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy
    • Larochelle, A., et al. (1996). Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy. Nat. Med. 2: 1329-1337.
    • (1996) Nat. Med. , vol.2 , pp. 1329-1337
    • Larochelle, A.1
  • 51
    • 0030925298 scopus 로고    scopus 로고
    • Kinetic evidence of regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immune-deficient mice
    • Cashman, J. D., et al. (1997). Kinetic evidence of regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immune-deficient mice. Blood 89: 4307-4316.
    • (1997) Blood , vol.89 , pp. 4307-4316
    • Cashman, J.D.1
  • 52
    • 0030911358 scopus 로고    scopus 로고
    • Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice
    • Bhatia, M., Wang, J. C. Y., Kapp, U., Bonnet, D., and Dick, J. E. (1997). Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice. Proc. Natl. Acad. Sci. USA 94: 5320-5325.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5320-5325
    • Bhatia, M.1    Wang, J.C.Y.2    Kapp, U.3    Bonnet, D.4    Dick, J.E.5
  • 53
    • 0030916733 scopus 로고    scopus 로고
    • Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay
    • Wang, J. C. Y., Doedens, M., and Dick, J. E. (1997). Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay. Blood 89: 3919-3924.
    • (1997) Blood , vol.89 , pp. 3919-3924
    • Wang, J.C.Y.1    Doedens, M.2    Dick, J.E.3
  • 54
    • 0030756218 scopus 로고    scopus 로고
    • Differential maintenance of primitive human SCID-repopulating cells, clonogenic progenitors, and long-term culture-initiating cells after incubation on human bone marrow stromal cells
    • Gan, O. I., Murdoch, B., Larochelle, A., and Dick, J. E. (1997). Differential maintenance of primitive human SCID-repopulating cells, clonogenic progenitors, and long-term culture-initiating cells after incubation on human bone marrow stromal cells. Blood 90: 641-650.
    • (1997) Blood , vol.90 , pp. 641-650
    • Gan, O.I.1    Murdoch, B.2    Larochelle, A.3    Dick, J.E.4
  • 55
    • 0030985905 scopus 로고    scopus 로고
    • +-enriched cells from umbilical cord blood in NOD/Ltz-scid/scid mice
    • +-enriched cells from umbilical cord blood in NOD/Ltz-scid/scid mice. Blood 90: 85-96.
    • (1997) Blood , vol.90 , pp. 85-96
    • Hogan, C.J.1
  • 56
    • 0030886656 scopus 로고    scopus 로고
    • Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic scid/scid mice
    • Conneally, E., Cashman, J., Petzer, A., and Eaves, C. (1997). Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic scid/scid mice. Proc. Natl. Acad. Sci. USA 94: 9836-9841.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9836-9841
    • Conneally, E.1    Cashman, J.2    Petzer, A.3    Eaves, C.4
  • 57
    • 0032190418 scopus 로고    scopus 로고
    • Nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mouse as a model system to study the engraftment and mobilization of human peripheral stem cells
    • Van der Loo, J. C. M., Hanenberg, H., Cooper, R. J., Luo, F. Y., Lazaridis, E. N., and Williams, D. A. (1998). Nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mouse as a model system to study the engraftment and mobilization of human peripheral stem cells. Blood 92: 2556-2570.
    • (1998) Blood , vol.92 , pp. 2556-2570
    • Van Der Loo, J.C.M.1    Hanenberg, H.2    Cooper, R.J.3    Luo, F.Y.4    Lazaridis, E.N.5    Williams, D.A.6
  • 58
    • 0033230393 scopus 로고    scopus 로고
    • Seeding efficiency of primitive human hematopoietic cells in nonobese diabetic/severe combined immune deficiency mice: Implications for stem cell frequency assessment
    • van Hennik, P. B., de Koning, A. E., and Ploemacher, R. E. (1999). Seeding efficiency of primitive human hematopoietic cells in nonobese diabetic/severe combined immune deficiency mice: Implications for stem cell frequency assessment. Blood 34: 3055-3061.
    • (1999) Blood , vol.34 , pp. 3055-3061
    • Van Hennik, P.B.1    De Koning, A.E.2    Ploemacher, R.E.3
  • 59
    • 19144361831 scopus 로고    scopus 로고
    • Frequency analysis of multidrug resistance-1 gene transfer into human primitive hematopoietic progenitor cells using the cobblestone area-forming cell assay and detection of vector-mediated P-glycoprotein expression by rhodamine-123
    • Fruehauf, S., et al. (1996). Frequency analysis of multidrug resistance-1 gene transfer into human primitive hematopoietic progenitor cells using the cobblestone area-forming cell assay and detection of vector-mediated P-glycoprotein expression by rhodamine-123. Hum. Gene Ther. 7: 1219-1231.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1219-1231
    • Fruehauf, S.1
  • 60
    • 0032213335 scopus 로고    scopus 로고
    • High efficiency gene transfer to human hematopoietic SCID-repopulating cells under serum-free conditions
    • Schilz, A. J., et al. (1998). High efficiency gene transfer to human hematopoietic SCID-repopulating cells under serum-free conditions. Blood 92: 3163-3171.
    • (1998) Blood , vol.92 , pp. 3163-3171
    • Schilz, A.J.1
  • 61
    • 0034724857 scopus 로고    scopus 로고
    • Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
    • Cavazzana-Calvo, M., et al. (2000). Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. Science 288: 669-672.
    • (2000) Science , vol.288 , pp. 669-672
    • Cavazzana-Calvo, M.1
  • 62
    • 0007659129 scopus 로고    scopus 로고
    • + stem cells using RetroNectin coated X-Fold gas permeable bags applied to treatment of X-linked chronic granulomatous disease (X-CGD)
    • + stem cells using RetroNectin coated X-Fold gas permeable bags applied to treatment of X-linked chronic granulomatous disease (X-CGD) [Abstract]. Mol. Ther. 5: S101-S102.
    • (2000) Mol. Ther. , vol.5
    • Malech, H.I.1
  • 63
    • 0007704259 scopus 로고    scopus 로고
    • Multiple cycles of ex vivo gene therapy for X-linked chronic granulomatous disease (CGD) sustain production of oxidase-normal peripheral blood neutrophils
    • Malech, H. I., et al. (2000). Multiple cycles of ex vivo gene therapy for X-linked chronic granulomatous disease (CGD) sustain production of oxidase-normal peripheral blood neutrophils [Abstract]. Mol. Ther. 5: S146.
    • (2000) Mol. Ther. , vol.5
    • Malech, H.I.1
  • 64
    • 0032056367 scopus 로고    scopus 로고
    • Efficient retroviral-mediated gene transfer to human cord blood stem cells with in vivo repopulating potential
    • Conneally, E., Eaves, C. J., and Humphries, R. K. (1998). Efficient retroviral-mediated gene transfer to human cord blood stem cells with in vivo repopulating potential. Blood 91: 3487-3493.
    • (1998) Blood , vol.91 , pp. 3487-3493
    • Conneally, E.1    Eaves, C.J.2    Humphries, R.K.3
  • 65
    • 0032126897 scopus 로고    scopus 로고
    • Retrovirus-mediated gene transfer into human CD34+38 low primitive cells capable of reconstituting long-term cultures in vitro and nonobese diabetic-severe combined immunodeficiency mice in vivo
    • Marandin, A., et al. (1998). Retrovirus-mediated gene transfer into human CD34+38 low primitive cells capable of reconstituting long-term cultures in vitro and nonobese diabetic-severe combined immunodeficiency mice in vivo. Hum. Gene Ther. 9: 1497-1511.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 1497-1511
    • Marandin, A.1
  • 66
    • 0032402140 scopus 로고    scopus 로고
    • Highly efficient transduction of the green fluorescent protein in human umbilical cord blood stem cells capable of cobblestone formation in long-term cultures and multilineage engraftment of immunodeficient mice
    • Van Hennik, P. B., et al. (1998). Highly efficient transduction of the green fluorescent protein in human umbilical cord blood stem cells capable of cobblestone formation in long-term cultures and multilineage engraftment of immunodeficient mice. Blood 92: 4013-4022.
    • (1998) Blood , vol.92 , pp. 4013-4022
    • Van Hennik, P.B.1
  • 67
    • 0034657444 scopus 로고    scopus 로고
    • Efficient transduction of human hematopoietic repopulating cells generating stable engraftment of transgene-expressing cells in NOD/SCID mice
    • Barquinero, J., et al. (2000). Efficient transduction of human hematopoietic repopulating cells generating stable engraftment of transgene-expressing cells in NOD/SCID mice. Blood 95: 3085-3093.
    • (2000) Blood , vol.95 , pp. 3085-3093
    • Barquinero, J.1
  • 68
    • 0029058758 scopus 로고
    • Expression of retroviral vectors containing the human multidrug resistance 1 cDNA in hematopoietic cells of transplanted mice
    • Sorrentino, B. P., McDonagh, K. T., Woods, D., and Orlic, D. (1995). Expression of retroviral vectors containing the human multidrug resistance 1 cDNA in hematopoietic cells of transplanted mice. Blood 86: 491-501.
    • (1995) Blood , vol.86 , pp. 491-501
    • Sorrentino, B.P.1    McDonagh, K.T.2    Woods, D.3    Orlic, D.4
  • 69
    • 0032505749 scopus 로고    scopus 로고
    • Poor expression of MDR1 transgene in HeLa cells by bicistronic Moloney murine leukemia virus-based vector
    • Zaboikin, M. M., and Schuening, F. G. (1998). Poor expression of MDR1 transgene in HeLa cells by bicistronic Moloney murine leukemia virus-based vector. Hum. Gene Ther. 9: 2263-2275.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 2263-2275
    • Zaboikin, M.M.1    Schuening, F.G.2
  • 70
    • 0031435428 scopus 로고    scopus 로고
    • Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species
    • Goodell, M. A., et al. (1997). Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat. Med. 3: 1337-1345.
    • (1997) Nat. Med. , vol.3 , pp. 1337-1345
    • Goodell, M.A.1
  • 71
    • 0028230779 scopus 로고
    • Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo
    • Challita, P.-M., and Kohn, D. B. (1994). Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo. Proc. Natl. Acad. Sci. USA 91: 2567-2571.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2567-2571
    • Challita, P.-M.1    Kohn, D.B.2
  • 72
    • 0030483546 scopus 로고    scopus 로고
    • Transcriptional silencing of retroviral vectors
    • Lund, A. H., Duch, M., and Pedersen, F. S. (1996). Transcriptional silencing of retroviral vectors. J. Biomed. Sci. 3: 365-378.
    • (1996) J. Biomed. Sci. , vol.3 , pp. 365-378
    • Lund, A.H.1    Duch, M.2    Pedersen, F.S.3
  • 73
    • 0033064966 scopus 로고    scopus 로고
    • Amelioration of retroviral vector silencing in locus control region beta-globin-transgenic mice and transduced F9 embryonic cells
    • Osborne, C. S., Pasceri, P., Singal, R., Sukonnik, T., Cinder, G. D., and Ellis, J. (1999). Amelioration of retroviral vector silencing in locus control region beta-globin-transgenic mice and transduced F9 embryonic cells. J. Virol. 73: 5490-5496.
    • (1999) J. Virol. , vol.73 , pp. 5490-5496
    • Osborne, C.S.1    Pasceri, P.2    Singal, R.3    Sukonnik, T.4    Cinder, G.D.5    Ellis, J.6
  • 74
    • 0033951116 scopus 로고    scopus 로고
    • Variegation of retroviral vector gene expression in myeloid cells
    • Zentilin, L., Qin, G., Tafuro, S., Dinauer, M. C., Baum, C., and Giacca, M. (2000). Variegation of retroviral vector gene expression in myeloid cells. Gene Ther. 7: 153-166.
    • (2000) Gene Ther. , vol.7 , pp. 153-166
    • Zentilin, L.1    Qin, G.2    Tafuro, S.3    Dinauer, M.C.4    Baum, C.5    Giacca, M.6
  • 75
    • 0032188998 scopus 로고    scopus 로고
    • Transduction of murine bone marrow cells with an MDR1 vector enables ex vivo stem cell expansion, but these expanded grafts cause a myeloproliferative syndrome in transplanted mice
    • Bunting, K. D., Galipeau, J., Topham, D., Benaim, E., and Sorrentino, B. P. (1998). Transduction of murine bone marrow cells with an MDR1 vector enables ex vivo stem cell expansion, but these expanded grafts cause a myeloproliferative syndrome in transplanted mice. Blood 92: 2269-2279.
    • (1998) Blood , vol.92 , pp. 2269-2279
    • Bunting, K.D.1    Galipeau, J.2    Topham, D.3    Benaim, E.4    Sorrentino, B.P.5
  • 76
    • 0039095310 scopus 로고    scopus 로고
    • Transplantation of rhesus hematopoietic cells with an MDR1 vector does not result in ex vivo or in vivo expansion or a myeloproliferative syndrome
    • Dunbar, C., et al. (2000). Transplantation of rhesus hematopoietic cells with an MDR1 vector does not result in ex vivo or in vivo expansion or a myeloproliferative syndrome. Mol. Ther. 5: 31-32.
    • (2000) Mol. Ther. , vol.5 , pp. 31-32
    • Dunbar, C.1
  • 77
    • 0025939045 scopus 로고
    • Chemotherapy and chemosensitization of transgenic mice which express the human multidrug resistance gene in bone marrow: Efficacy, potency, and toxicity
    • Mickisch, G. H., Licht, T., Merlino, G. T., Gottesman, M. M., and Pastan, I. (1991). Chemotherapy and chemosensitization of transgenic mice which express the human multidrug resistance gene in bone marrow: Efficacy, potency, and toxicity. Cancer Res. 51: 5417-5424.
    • (1991) Cancer Res. , vol.51 , pp. 5417-5424
    • Mickisch, G.H.1    Licht, T.2    Merlino, G.T.3    Gottesman, M.M.4    Pastan, I.5


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