Cold climate genes and the prevalence of type 2 diabetes mellitus

Medical Hypotheses

Volumn 67, Issue 5, 2006, Pages 1034-1041

  Fridlyand, Leonid E ^a   Philipson, Louis H ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN;

ADAPTATION; ALLELE; ARTICLE; BIOGENESIS; COLD CLIMATE; DISEASE PREDISPOSITION; EUROPE; HEAT; HUMAN; METABOLIC RATE; MITOCHONDRIAL GENETICS; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; THERMOGENESIS;

ACCLIMATIZATION; ASIAN CONTINENTAL ANCESTRY GROUP; COLD CLIMATE; DIABETES MELLITUS, TYPE 2; ETHNIC GROUPS; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INDIANS, NORTH AMERICAN; PREVALENCE; RURAL POPULATION; URBAN POPULATION;

EID: 33748453913     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2006.04.057     Document Type: Article

References (49)

1. Diamond J. The double puzzle of diabetes. Nature 423 (2003) 599-602
2. Nakagami T., Qiao Q., Carstensen B., et al. The DECODE-DECODA study group. Age, body mass index and Type 2 diabetes-associations modified by ethnicity. Diabetologia 46 (2003) 1063-1070
3. Dabelea D., and Hamman R.F. Epidemiology of Type 2 diabetes mellitus. In: LeRoith D., Taylor S.I., and Olefsky J.M. (Eds). Diabetes mellitus. A fundamental and clinical text (2004), Lippincott Williams & Wilkins, Philadelphia 785-796
4. DECODE Study Group. Age- and sex-specific prevalences of diabetes and impaired glucose regulation in 13 European cohorts. Diabetes Care 26 (2003) 61-69
5. Neel J.V. Diabetes mellitus: a thrifty genotype rendered detrimental by progress. Am J Hum Genet 14 (1962) 353-362
6. Younis N., Soran H., and Farook S. The prevention of type 2 diabetes mellitus: recent advances. QJM 97 (2004) 451-455
7. McKeigue P.M., Shah B., and Marmot M.G. Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians. Lancet 337 (1991) 382-386
8. Whincup P.H., Gilg J.A., Owen C.G., Odoki K., Alberti K.G., and Cook D.G. British South Asians aged 13-16 years have higher fasting glucose and insulin levels than Europeans. Diabetic Med 22 (2005) 1275-1277
9. McNeely M.J., and Boyko E.J. Type 2 diabetes prevalence in Asian Americans: results of a national health survey. Diabetes Care 27 (2004) 66-69
10. Jenum A.K., Holme I., Graff-Iversen S., and Birkeland K.I. Ethnicity and sex are strong determinants of diabetes in an urban Western society: implications for prevention. Diabetologia 48 (2005) 435-439
11. Bjerregaard P., Young T.K., Dewailly E., and Ebbesson S.O. Indigenous health in the Arctic: an overview of the circumpolar Inuit population. Scand J Public Health 32 (2004) 390-395
12. Gamble C., Davies W., Pettitt P., and Richards M. Climate change and evolving human diversity in Europe during the last glacial. Philos Trans Roy Soc Lond B, Biol Sci 359 (2004) 243-253
13. Haak W., Forster P., Bramanti B., et al. Ancient DNA from the first European farmers in 7500-year-old Neolithic sites. Science 310 (2005) 1016-1018
14. Jansky L. Humoral thermogenesis and its role in maintaining energy balance. Physiol Rev 75 (1995) 237-259
15. Lowell B.B., and Spiegelman B.M. Towards a molecular understanding of adaptive thermogenesis. Nature 404 (2000) 652-660
16. Ravussin E., Lillioja S., Anderson T.E., Christin L., and Bogardus C. Determinants of 24-hour energy expenditure in man. Methods and results using a respiratory chamber. J Clin Invest 78 (1986) 1568-1578
17. Rolfe D.F., and Brown G.C. Cellular energy utilization and molecular origin of standard metabolic rate in mammals. Physiol Rev 77 (1997) 731-758
18. Gannon B., DiPietro L., and Poehlman E.T. Do African Americans have lower energy expenditure than Caucasians?. Int J Obes Relat Metab Disord 24 (2000) 4-13
19. Kimm S.Y., Glynn N.W., Aston C.E., et al. Racial differences in the relation between uncoupling protein genes and resting energy expenditure. Am J Clin Nutr 75 (2002) 714-719
20. McDuffie J.R., Adler-Wailes D.C., Elberg J., et al. Prediction equations for resting energy expenditure in overweight and normal-weight black and white children. Am J Clin Nutr 80 (2004) 365-373
21. Rush E.C., Plank L.D., and Robinson S.M. Resting metabolic rate in young Polynesian and Caucasian women. Int J Obes Relat Metab Disord 21 (1997) 1071-1075
22. Soares M.J., Francis D.G., and Shetty P.S. Predictive equations for basal metabolic rates of Indian males. Eur J Clin Nutr 47 (1993) 389-394
23. Henry C.J., and Rees D.G. New predictive equations for the estimation of basal metabolic rate in tropical peoples. Eur J Clin Nutr 45 (1991) 177-185
24. Leonard W.R., Sorensen M.V., Galloway V.A., Spencer G.J., Mosher M.J., et al. Climatic influences on basal metabolic rates among circumpolar populations. Am J Hum Biol 14 (2002) 609-620
25. Snodgrass J.J., Leonard W.R., Tarskaia L.A., Alekseev V.P., Krivoshapkin V.G., et al. Basal metabolic rate in the Yakut (Sakha) of Siberia. Am J Hum Biol 17 (2005) 155-172
26. Turrens J.F. Mitochondrial formation of reactive oxygen species. J Physiol 552 (2003) 335-344
27. Rolfe D.F.S., and Brand M.D. The physiological significance of mitochondrial proton leak in animal cells and tissues. Biosci Rep 17 (1997) 9-16
28. Bell G.I., and Polonsky K.S. Diabetes mellitus and genetically programmed defects in beta-cell function. Nature 414 (2001) 788-791
29. Kahn S.E. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes. Diabetologia 46 (2003) 3-19
30. Fridlyand L.E., and Philipson L.H. Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells. Diabetes 53 (2004) 1942-1948
31. Fridlyand L.E., and Philipson L.H. Reactive species, cellular repair and risk factors in the onset of type 2 diabetes mellitus: review and hypothesis. Curr Diabetes Rev 2 (2006) 241-259
32. Bouchard C., Perusse L., Chagnon Y.C., Warden C., and Ricquier D. Linkage between markers in the vicinity of the uncoupling protein 2 gene and resting metabolic rate in humans. Hum Mol Genet 6 (1997) 1887-1889
33. Yu X., Jacobs Jr. D.R., Schreiner P.J., et al. The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA study. Clin Chem 51 (2005) 1451-1456
34. Astrup A., Toubro S., Dalgaard L.T., et al. Impact of the v/v 55 polymorphism of the uncoupling protein 2 gene on 24-h energy expenditure and substrate oxidation. Int J Obes Relat Metab Disord 23 (1999) 1030-1034
35. Buemann B., Schierning B., Toubro S., et al. The association between the Val/Ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency. Int J Obes Relat Metab Disord 25 (2001) 467-471
36. Wang H., Chu W.S., Lu T., Hasstedt S.J., Kern P.A., and Elbein S.C. Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion. Am J Physiol Endocrinol Metab 286 (2004) E1-E7
37. Solanes G., Vidal-Puig A., Grujic D., Flier J.S., and Lowell B.B. The human uncoupling protein-3 gene Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts. J Biol Chem 272 (1997) 25433-25436
38. Hesselink M.K., and Schrauwen P. Towards comprehension of the physiological role of UCP3. Horm Metab Res 37 (2005) 550-554
39. 2-adrenergic stimulation on energy expenditure, substrate oxidation, and UCP3 expression in humans. Am J Physiol Endocrinol Metab 285 (2003) 775-782
40. Schrauwen P., Xia J., Bogardus C., Pratley R.E., and Ravussin E. Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians. Diabetes 48 (1999) 146-149
41. Wallace D.C. Mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet 39 (2005) 359-407
42. Kelly D.P., and Scarpulla R.C. Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev 18 (2004) 357-368
43. Patti M.E., Butte A.J., Crunkhorn S., et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1. Proc Natl Acad Sci USA 100 (2003) 8466-8471
44. Muller Y.L., Bogardus C., Pedersen O., and Baier L.A. Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians. Diabetes 52 (2003) 895-898
45. Canani L.H., Capp C., Dora J.M., et al. The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 90 (2005) 3472-3478
46. Coleman D.L. Diabetes-obesity syndromes in mice. Diabetes 31 Suppl. 1, Pt 2 (1982) 1-6
47. Shafrir E., and Ziv E. Cellular mechanism of nutritionally induced insulin resistance: the desert rodent Psammomys obesus and other animals in which insulin resistance leads to detrimental outcome. J Basic Clin Physiol Pharmacol 9 (1998) 347-385
48. Cannon B., and Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol Rev 84 (2004) 277-359
49. Malik M., Bakir A., Saab B.A., Roglic G., and King H. Glucose intolerance and associated factors in the multi-ethnic population of the United Arab Emirates: results of a national survey. Diabetes Res Clin Pract 69 (2005) 188-195