Alcohol impairs leucine-mediated phosphorylation of 4E-BP1, S6K1, eIF4G, and mTOR in skeletal muscle

American Journal of Physiology - Endocrinology and Metabolism

Volumn 285, Issue 6 48-6, 2003, Pages

  Lang, Charles H ^a   Frost, Robert A ^a   Deshpande, Nobuko ^a   Kumar, Vinayshree ^a   Vary, Thomas C ^a   Jefferson, Leonard S ^a   Kimball, Scot R ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

4E binding protein 1; Ethanol; Eukaryotic initiation factor 4G; Gastrocnemius; Glucocorticoids; Mammalian target of rapamycin; Rat; Serine threonine protein kinase

Indexed keywords

ALCOHOL; BINDING PROTEIN; CORTISONE; GLUCOCORTICOID; INITIATION FACTOR 4E BINDING PROTEIN 1; INITIATION FACTOR 4G; INSULIN; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; MIFEPRISTONE; PROTEIN SERINE THREONINE KINASE; S6 KINASE; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; COMPLEX FORMATION; CONTROLLED STUDY; GASTROCNEMIUS MUSCLE; HORMONE BLOOD LEVEL; INSULIN BLOOD LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TRANSLATION REGULATION;

EID: 0344464784     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00177.2003     Document Type: Article

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