Increased protein synthesis after acute IGF-I or insulin infusion is localized to muscle in mice

American Journal of Physiology - Endocrinology and Metabolism

Volumn 275, Issue 1 38-1, 1998, Pages

  Bark, Tor H ^a,b   McNurlan, Margaret A ^a   Lang, Charles H ^a   Garlick, Peter J ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Feeding; Intestine; Kidney; Liver; 2H5 phenylalanine

Indexed keywords

SOMATOMEDIN C;

ANIMAL TISSUE; ARTICLE; CONTINUOUS INFUSION; FEEDING; GASTROCNEMIUS MUSCLE; HYPOGLYCEMIA; INSULIN INFUSION; MOUSE; MUSCLE METABOLISM; NONHUMAN; PLANTARIS MUSCLE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS REGULATION;

EID: 0031856578     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1998.275.1.e118     Document Type: Article

References (27)

1. Baillie, A. G., and P. J. Garlick. Responses of protein synthesis in different skeletal muscles to fasting and insulin in the rat. Am. J. Physiol. 260 (Endocrinol. Metab. 23): E891-E896, 1991.
2. Baillie, A. G., and P. J. Garlick. Attenuated response of muscle protein synthesis to fasting and insulin in adult female rats. Am. J. Physiol. 262 (Endocrinol. Metab. 25): E1-E5, 1992.
3. Clemmons, D. R., and L. E. Underwood. Role of insulin-like growth factors and growth hormone in reversing catabolic states. Horm. Res. 38, Suppl. 2: 37-40, 1992.
4. Douglas, R. G., P. D. Gluckman, K. Ball, B. Breier, and J. H. Shaw. The effects of infusion of insulin-like growth factor (IGF) I, IGF-II, and insulin on glucose and protein metabolism in fasted lambs. J. Clin. Invest. 88: 614-622, 1991.
5. Fan, J., P. E. Molina, M. C. Gelato, and C. H. Lang. Differential tissue regulation of insulin-like growth factor-I content and binding proteins after endotoxin. Endocrinology 134: 1685-1692, 1994.
6. Fryburg, D. A. Insulin-like growth factor I exerts growth hormone- and insulin-like actions on human muscle protein metabolism. Am. J. Physiol. 267 (Endocrinol. Metab. 30): E331-E336, 1994.
7. Fuller, S. J., J. R. Mynett, and P. H. Sugden. Stimulation of cardiac protein synthesis by insulin-like growth factors. Biochem. J. 282: 85-90, 1992.
8. Garlick, P. J., M. Fern, and V. R. Preedy. The effect of insulin infusion and food intake on muscle protein synthesis in postabsorptive rats. Biochem. J. 210: 669-676, 1983.
9. Garlick, P. J., M. A. McNurlan, P. Essén, and J. Wernerman. Measurement of tissue protein synthesis rates in vivo: a critical analysis of contrasting methods. Am. J. Physiol. 266 (Endocrinol. Metab. 29): E287-E297, 1994.
10. 3H-phenylalanine. Biochem. J. 192: 719-723, 1980.
11. Garlick, P. J., and J. Wernerman. Protein metabolism in injury. In: Scientific Foundations of Trauma, edited by G. J. Cooper, H. A. F. Dudley, D. S. Gann, R. A. Little, and R. L. Maynard. Oxford, UK: Butterworth-Heinemann, 1997, p. 690-727.
12. Huang, K. F., D. H. Chung, and D. N. Herndon. Insulinlike growth factor 1 (IGF-1) reduces gut atrophy and bacterial translocation after severe burn injury. Arch. Surg. 128: 47-54, 1993.
13. Jacob, R., E. Barrett, G. Plewe, K. D. Fagin, and R. S. Sherwin. Acute effects of insulin-like growth factor I on glucose and amino acid metabolism in the awake fasted rat. J. Clin. Invest. 83: 1717-1723, 1989.
14. Jacob, R., X. Hu, D. Niederstock, S. Hasan, P. H. McNulty, R. S. Sherwin, and L. H. Young. IGF-I stimulation of muscle protein synthesis in the awake rat: permissive role of insulin and amino acids. Am. J. Physiol. 270 (Endocrinol. Metab. 33): E60-E66, 1996.
15. Jurasinski, C. V., and T. C. Vary. Insulin-like growth factor I accelerates protein synthesis in skeletal muscle during sepsis. Am. J. Physiol. 269 (Endocrinol. Metab. 32): E977-E981, 1995.
16. LeRoith, D., H. Werner, D. Beitner-Johnson, and C. T. Roberts, Jr. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr. Rev. 16: 143-163, 1995.
17. 5]phenylalanine. Am. J. Physiol. 267 (Endocrinol. Metab. 30): E102-E108, 1994.
18. Pascual, M., J. Larralde, and J. A. Martinez. Organ-specific effects and interactions of acute insulin-like growth factor I (IGF-I) and growth hormone. Growth Dev. Aging 59: 181-191, 1995.
19. Preedy, V. R., and P. J. Garlick. The response of muscle protein synthesis to nutrient intake in postabsorptive rats: the role of insulin and amino acids. Biosci. Rep. 6: 177-182, 1986.
20. Reeds, P. J., S. M. Hay, R. T. Glennie, W. S. Mackie, and P. J. Garlick. The effect of indomethacin on the stimulation of protein synthesis by insulin in young post-absorptive rats. Biochem. J. 227: 255-261, 1985.
21. Russell-Jones, D. L., A. M. Umpleby, T. R. Hennessy, S. B. Bowes, F. Shojaee-Moradie, K. D. Hopkins, N. C. Jackson, J. M. Kelly, R. H. Jones, and P. H. Sönksen. Use of a leucine clamp to demonstrate that IGF-I actively stimulates protein synthesis in normal humans. Am. J. Physiol. 267 (Endocrinol. Metab. 30): E591-E598, 1994.
22. Sandstedt, S., L. Jorfeldt, and J. Larsson. Randomized, controlled study evaluating effects of branched chain amino acids and alpha-ketoisocaproate on protein metabolism after surgery. Br. J. Surg. 79: 217-220, 1992.
23. Sandström, R., E. Svanberg, A. Hyltander, E. Haglind, C. Ohlsson, H. Zachrisson, B. Berglund, E. Lindholm, H. Brevinge, and K. Lundholm. The effect of recombinant human IGF-I on protein metabolism in post-operative patients without nutrition compared to effects in experimental animals. Eur. J. Clin. Invest. 25: 784-792, 1995.
24. Steeb, C. B., J. F. Trahair, and L. C. Read. Administration of insulin-like growth factor-I (IGF-I) peptides for three days stimulates proliferation of the small intestinal epithelium in rats. Gut 37: 630-638, 1995.
25. Svanberg, E., H. Zachrisson, C. Ohlsson, B. M. Iresjö, and K. G. Lundholm. Role of insulin and IGF-I in activation of muscle protein synthesis after oral feeding. Am. J. Physiol. 270 (Endocrinol. Metab. 33): E614-E620, 1996.
26. Waterlow, J. C., P. J. Garlick, and D. J. Millward. Protein Turnover in Mammalian Tissues and in the Whole Body. Amsterdam: North Holland, 1978.
27. Wojnar, M. M., J. Fan, R. A. Frost, M. C. Gelato, and C. H. Lang. Alterations in the insulin-like growth factor system in trauma patients. Am. J. Physiol. 269 (Regulatory Integrative Comp. Physiol. 38): R970-R977, 1995.