Differential activation of extracellular signal-regulated protein kinase in primary afferent neurons regulates brain-derived neurotrophic factor expression after peripheral inflammation and nerve injury

Journal of Neuroscience

Volumn 23, Issue 10, 2003, Pages 4117-4126

  Obata, Koichi ^a,b   Yamanaka, Hiroki ^a   Dai, Yi ^a   Tachibana, Toshiya ^a   Fukuoka, Tetsuo ^a   Tokunaga, Atsushi ^a   Yoshikawa, Hideki ^b   Noguchi, Koichi ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Axotomy; Brain derived neurotrophic factor; Complete Freund's adjuvant; Dorsal root ganglion; Extracellular signal regulated protein kinase; Mitogen activated protein kinase

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; BRAIN DERIVED NEUROTROPHIC FACTOR; FREUND ADJUVANT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; 1,3 BUTADIENE DERIVATIVE; ACTIVATING TRANSCRIPTION FACTOR 3; ATF3 PROTEIN, RAT; ENZYME INHIBITOR; GLIAL FIBRILLARY ACIDIC PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NEUROFILAMENT PROTEIN; NEUROFILAMENT PROTEIN H; NITRILE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL LABELING; CELL POPULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE CONTROL; GENE EXPRESSION REGULATION; GLIA CELL; INFLAMMATION; MALE; MUSCLE SPINDLE AFFERENT NERVE; NERVE FIBER TRANSECTION; NOCICEPTION; NONHUMAN; PATHOPHYSIOLOGY; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SATELLITE CELL; SCIATIC NERVE; SIGNAL TRANSDUCTION; SPINAL GANGLION; ANIMAL; ANIMAL BEHAVIOR; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; GENETICS; GLIA; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INJURY; INTRASPINAL DRUG ADMINISTRATION; METABOLISM; PAIN THRESHOLD; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SENSORY NERVE CELL; SPRAGUE DAWLEY RAT;

ACTIVATING TRANSCRIPTION FACTOR 3; ANIMALS; AXOTOMY; BEHAVIOR, ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; BUTADIENES; ENZYME ACTIVATION; ENZYME INHIBITORS; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INJECTIONS, SPINAL; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROFILAMENT PROTEINS; NEUROGLIA; NEURONS, AFFERENT; NITRILES; PAIN THRESHOLD; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; TRANSCRIPTION FACTORS;

EID: 0037704450     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-10-04117.2003     Document Type: Article

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