메뉴 건너뛰기




Volumn 12, Issue 2, 2006, Pages 113-122

Humanin and colivelin: Neuronal-death-suppressing peptides for Alzheimer's disease and amyotrophic lateral sclerosis

Author keywords

Amyloid; Alzheimer's disease; Amyotrophic lateral sclerosis; Colivelin; Humanin

Indexed keywords

ACTIVITY DEPENDENT NEUROTROPHIC FACTOR; COLIVELIN; HUMANIN; JANUS KINASE 2; NEUROPROTECTIVE AGENT; NEUROTROPHIC FACTOR; PEPTIDE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; UNCLASSIFIED DRUG;

EID: 33748049127     PISSN: 1080563X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1527-3458.2006.00113.x     Document Type: Review
Times cited : (46)

References (54)
  • 1
    • 0029883129 scopus 로고    scopus 로고
    • A femtomolar-acting neuroprotective peptide
    • Brenneman DE, Gozes I. A femtomolar-acting neuroprotective peptide. J Clin Invest 1996;97:2299-2307.
    • (1996) J Clin Invest , vol.97 , pp. 2299-2307
    • Brenneman, D.E.1    Gozes, I.2
  • 2
    • 3943102116 scopus 로고    scopus 로고
    • Unraveling the mechanisms involved in motor neuron degeneration in ALS
    • Bruijn LI, Miller TM, Cleveland DW. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci 2004;27:723-749.
    • (2004) Annu Rev Neurosci , vol.27 , pp. 723-749
    • Bruijn, L.I.1    Miller, T.M.2    Cleveland, D.W.3
  • 3
    • 0036673025 scopus 로고    scopus 로고
    • A novel rat gene encoding a humanin-like peptide endowed with broad neuroprotective activity
    • Caricasole A, Bruno V, Cappuccio I, Melchiorri D, Copani A, Nicoletti F. A novel rat gene encoding a humanin-like peptide endowed with broad neuroprotective activity. FASEB J 2002; 16:1331-1333.
    • (2002) FASEB J , vol.16 , pp. 1331-1333
    • Caricasole, A.1    Bruno, V.2    Cappuccio, I.3    Melchiorri, D.4    Copani, A.5    Nicoletti, F.6
  • 4
    • 8844270200 scopus 로고    scopus 로고
    • Neuroprotective effect of activity-dependent neurotrophic factor against toxicity from familial amyotrophic lateral sclerosis-linked mutant SOD1 in vitro and in vivo
    • Chiba T, Hashimoto Y, Tajima H et al. Neuroprotective effect of activity-dependent neurotrophic factor against toxicity from familial amyotrophic lateral sclerosis-linked mutant SOD1 in vitro and in vivo. J Neurosci Res 2004;78:542-552.
    • (2004) J Neurosci Res , vol.78 , pp. 542-552
    • Chiba, T.1    Hashimoto, Y.2    Tajima, H.3
  • 5
    • 27744563035 scopus 로고    scopus 로고
    • Development of a femtomolar-acting Humanin derivative named Colivelin by attaching ADNF to its N terminus: Characterization of colivelin-mediated neuroprotection against Alzheimer's disease-relevant insults in vitro and in vivo
    • Chiba T, Yamada M, Hashimoto Y et al. Development of a femtomolar-acting Humanin derivative named Colivelin by attaching ADNF to its N terminus: Characterization of colivelin-mediated neuroprotection against Alzheimer's disease-relevant insults in vitro and in vivo. J Neurosci 2005;25:10252-10261.
    • (2005) J Neurosci , vol.25 , pp. 10252-10261
    • Chiba, T.1    Yamada, M.2    Hashimoto, Y.3
  • 6
    • 33645944367 scopus 로고    scopus 로고
    • Colivelin prolongs survival of an ALS model mouse
    • Chiba T, Yamada M, Sasabe J, et al. Colivelin prolongs survival of an ALS model mouse. Biochem Biophys Res Commun 2006;343:793-798.
    • (2006) Biochem Biophys Res Commun , vol.343 , pp. 793-798
    • Chiba, T.1    Yamada, M.2    Sasabe, J.3
  • 7
    • 0035516124 scopus 로고    scopus 로고
    • From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
    • Cleveland DW, Rothstein JD. From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2001;2:806-819.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 806-819
    • Cleveland, D.W.1    Rothstein, J.D.2
  • 8
    • 0032551640 scopus 로고    scopus 로고
    • Characterization of human presenilin 1 transgenic rats: Increased sensitivity to apoptosis in primary neuronal cultures
    • Czech C, Lesort M, Tremp G, et al. Characterization of human presenilin 1 transgenic rats: Increased sensitivity to apoptosis in primary neuronal cultures. Neuroscience 1998;87:325-336.
    • (1998) Neuroscience , vol.87 , pp. 325-336
    • Czech, C.1    Lesort, M.2    Tremp, G.3
  • 9
    • 0033516567 scopus 로고    scopus 로고
    • Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F•DP, in β-amyloid-induced neuronal death
    • Giovanni A, Wirtz-Brugger F, Keramaris E, Slack R, Park DS. Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F•DP, in β-amyloid-induced neuronal death. J Biol Chem 1999;274: 19011-19016.
    • (1999) J Biol Chem , vol.274 , pp. 19011-19016
    • Giovanni, A.1    Wirtz-Brugger, F.2    Keramaris, E.3    Slack, R.4    Park, D.S.5
  • 10
    • 0029031348 scopus 로고
    • Apoptotic cell death induced by β-amyloid I-42 peptide is cell type dependent
    • Gschwind M, Huber G Apoptotic cell death induced by β-amyloid I-42 peptide is cell type dependent. J Neurochem 1995;65:292-300.
    • (1995) J Neurochem , vol.65 , pp. 292-300
    • Gschwind, M.1    Huber, G.2
  • 11
    • 0033016172 scopus 로고    scopus 로고
    • Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
    • Guo Q, Fu W, Sopher BL, et al. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nat Med 1999;5:101-106.
    • (1999) Nat Med , vol.5 , pp. 101-106
    • Guo, Q.1    Fu, W.2    Sopher, B.L.3
  • 12
    • 0038485614 scopus 로고    scopus 로고
    • Humanin peptide suppresses apoptosis by interfering with Bax activation
    • Guo B, Zhai D, Cabezas E, et al. Humanin peptide suppresses apoptosis by interfering with Bax activation. Nature 2003;423:456-461.
    • (2003) Nature , vol.423 , pp. 456-461
    • Guo, B.1    Zhai, D.2    Cabezas, E.3
  • 13
    • 0034785483 scopus 로고    scopus 로고
    • A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
    • Hadano S, Hand CK, Osuga H, et al. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat Genet 2001;29:166-173.
    • (2001) Nat Genet , vol.29 , pp. 166-173
    • Hadano, S.1    Hand, C.K.2    Osuga, H.3
  • 14
    • 4744351478 scopus 로고    scopus 로고
    • N-Formylated humanin activates both formyl peptide receptor-like 1 and 2
    • Harada M, Habata Y, Hosoya M, et al. N-Formylated humanin activates both formyl peptide receptor-like 1 and 2. Biochem Biophys Res Commun 2004;324:255-261.
    • (2004) Biochem Biophys Res Commun , vol.324 , pp. 255-261
    • Harada, M.1    Habata, Y.2    Hosoya, M.3
  • 15
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 2002;297:353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 16
    • 0034602331 scopus 로고    scopus 로고
    • Multiple mechanisms underlie neurotoxicity by different types of Alzheimer's disease mutations of amyloid precursor protein
    • Hashimoto Y, Niikura T, Ito Y, Nishimoto I. Multiple mechanisms underlie neurotoxicity by different types of Alzheimer's disease mutations of amyloid precursor protein. J Biol Chem 2000;275:34541-34551.
    • (2000) J Biol Chem , vol.275 , pp. 34541-34551
    • Hashimoto, Y.1    Niikura, T.2    Ito, Y.3    Nishimoto, I.4
  • 17
    • 4243333514 scopus 로고    scopus 로고
    • A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ
    • Hashimoto Y, Niikura T, Tajima H, et al. A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ. Proc Natl Acad Sci USA 2001;98:6336-6341.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6336-6341
    • Hashimoto, Y.1    Niikura, T.2    Tajima, H.3
  • 18
    • 3342993135 scopus 로고    scopus 로고
    • Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-beta peptides via p75NTR/PLAIDD
    • Hashimoto Y, Kaneko Y, Tsukamoto E, et al. Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-beta peptides via p75NTR/PLAIDD. J Neurochem 2004;90:549-558.
    • (2004) J Neurochem , vol.90 , pp. 549-558
    • Hashimoto, Y.1    Kaneko, Y.2    Tsukamoto, E.3
  • 19
    • 26444463390 scopus 로고    scopus 로고
    • Involvement of tyrosine kinases and STAT3 in Humanin-mediated neuroprotection
    • Hashimoto Y, Suzuki H, Aiso S, Niikura T, Nishimoto I, Matsuoka M. Involvement of tyrosine kinases and STAT3 in Humanin-mediated neuroprotection. Life Sci 2005;77:3092-3104
    • (2005) Life Sci , vol.77 , pp. 3092-3104
    • Hashimoto, Y.1    Suzuki, H.2    Aiso, S.3    Niikura, T.4    Nishimoto, I.5    Matsuoka, M.6
  • 20
    • 27144443047 scopus 로고    scopus 로고
    • Transforming growth factor beta2 is a neuronal death-inducing ligand for amyloid-beta precursor protein
    • Hashimoto Y, Chiba T, Yamada M, et al. Transforming growth factor beta2 is a neuronal death-inducing ligand for amyloid-beta precursor protein. Mol Cell Biol 2005;25:9304-9317.
    • (2005) Mol Cell Biol , vol.25 , pp. 9304-9317
    • Hashimoto, Y.1    Chiba, T.2    Yamada, M.3
  • 21
    • 33645857992 scopus 로고    scopus 로고
    • Transforming growth factor beta2 autocrinally mediates neuronal cell death induced by amyloid-beta
    • Hashimoto Y, Nawa M, Chiba T, Aiso S, Nishimoto I, Matsuoka M. Transforming growth factor beta2 autocrinally mediates neuronal cell death induced by amyloid-beta. J Neurosci Res 2006;83:1039-1047.
    • (2006) J Neurosci Res , vol.83 , pp. 1039-1047
    • Hashimoto, Y.1    Nawa, M.2    Chiba, T.3    Aiso, S.4    Nishimoto, I.5    Matsuoka, M.6
  • 22
    • 0028850087 scopus 로고
    • Suppression of mitochondrial succinate dehydrogenase, a primary target of β-amyloid, and its derivative racemized at Ser residue
    • Kaneko I, Yamada N, Sakuraba Y, Kamenosono M, Tutumi S. Suppression of mitochondrial succinate dehydrogenase, a primary target of β-amyloid, and its derivative racemized at Ser residue. J Neurochem 1995;65:2585-2593.
    • (1995) J Neurochem , vol.65 , pp. 2585-2593
    • Kaneko, I.1    Yamada, N.2    Sakuraba, Y.3    Kamenosono, M.4    Tutumi, S.5
  • 23
    • 14244264186 scopus 로고    scopus 로고
    • A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death
    • Kanekura K, Hashimoto Y, Kita Y, et al. A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death. J Biol Chem 2005;280:4532-4543.
    • (2005) J Biol Chem , vol.280 , pp. 4532-4543
    • Kanekura, K.1    Hashimoto, Y.2    Kita, Y.3
  • 24
    • 2442463319 scopus 로고    scopus 로고
    • Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants
    • Kanekura K, Hashimoto Y, Niikura T, Aiso S, Matsuoka M, Nishimoto I. Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants. J Biol Chem 2004;279:19247- 19256.
    • (2004) J Biol Chem , vol.279 , pp. 19247-19256
    • Kanekura, K.1    Hashimoto, Y.2    Niikura, T.3    Aiso, S.4    Matsuoka, M.5    Nishimoto, I.6
  • 26
    • 0042528664 scopus 로고    scopus 로고
    • Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
    • Kaspar BK, Llado J, Sherkat N, Rothstein JD, Gage FH. Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science 2003;301:839-842.
    • (2003) Science , vol.301 , pp. 839-842
    • Kaspar, B.K.1    Llado, J.2    Sherkat, N.3    Rothstein, J.D.4    Gage, F.H.5
  • 27
    • 0036769574 scopus 로고    scopus 로고
    • Molecular mechanisms for neuronal cell death by Alzheimer's amyloid precursor protein-relevant insults
    • Kawasumi M, Hashimoto Y, Chiba T, et al. Molecular mechanisms for neuronal cell death by Alzheimer's amyloid precursor protein-relevant insults. NeuroSignals 2002;11:236-250.
    • (2002) NeuroSignals , vol.11 , pp. 236-250
    • Kawasumi, M.1    Hashimoto, Y.2    Chiba, T.3
  • 28
    • 6944252056 scopus 로고    scopus 로고
    • Effect of humanin analogues on experimentally induced impairment of spatial memory in rats
    • Krejcova G, Patocka J, Slaninova J. Effect of humanin analogues on experimentally induced impairment of spatial memory in rats. J Pept Sci 2004;10:636-639.
    • (2004) J Pept Sci , vol.10 , pp. 636-639
    • Krejcova, G.1    Patocka, J.2    Slaninova, J.3
  • 29
    • 2942530300 scopus 로고    scopus 로고
    • Acetylcholinesterase and its inhibition in Alzheimer disease
    • Lane RM, Kivipelto M, Greig NH. Acetylcholinesterase and its inhibition in Alzheimer disease. Clin Neuropharmacol 2004;27:141-149.
    • (2004) Clin Neuropharmacol , vol.27 , pp. 141-149
    • Lane, R.M.1    Kivipelto, M.2    Greig, N.H.3
  • 31
    • 18144427811 scopus 로고    scopus 로고
    • Cytoprotective peptide humanin binds and inhibits proapoptotic Bcl-2/Bax family protein BimEL
    • Luciano F, Zhai D, Zhu X, et al. Cytoprotective peptide humanin binds and inhibits proapoptotic Bcl-2/Bax family protein BimEL. J Biol Chem 2005 280:15825-15835.
    • (2005) J Biol Chem , vol.280 , pp. 15825-15835
    • Luciano, F.1    Zhai, D.2    Zhu, X.3
  • 32
    • 0033104420 scopus 로고    scopus 로고
    • Death of PC12 cells and hippocampal neurons induced by adenoviral-mediated FAD human amyloid precursor protein gene expression
    • Luo JJ, Wallace W, Riccioni T, et al. Death of PC12 cells and hippocampal neurons induced by adenoviral-mediated FAD human amyloid precursor protein gene expression. J Neurosci Res 1999;55:629-642.
    • (1999) J Neurosci Res , vol.55 , pp. 629-642
    • Luo, J.J.1    Wallace, W.2    Riccioni, T.3
  • 33
    • 0035678839 scopus 로고    scopus 로고
    • Gly(14)-Humanin improved the learning and memory impairment induced by scopolamine in vivo
    • Mamiya T, Ukai M. [Gly(14)]-Humanin improved the learning and memory impairment induced by scopolamine in vivo. Br J Pharmacol 2001;134:1597-1599.
    • (2001) Br J Pharmacol , vol.134 , pp. 1597-1599
    • Mamiya, T.1    Ukai, M.2
  • 37
    • 0032053984 scopus 로고    scopus 로고
    • Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer
    • Nishimura I, Uetsuki T, Dani SU, et al. Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer. J Neurosci 1998;18: 2387-2398.
    • (1998) J Neurosci , vol.18 , pp. 2387-2398
    • Nishimura, I.1    Uetsuki, T.2    Dani, S.U.3
  • 38
    • 0030924506 scopus 로고    scopus 로고
    • Aβ-amyloid neurotoxicity in vitro: Evidence of oxidative stress but not protection by antioxidants
    • Pike CJ, Ramezan-Arab N, Cotman CW. Aβ-amyloid neurotoxicity in vitro: Evidence of oxidative stress but not protection by antioxidants. J Neurochem 1997;69:1601-1611.
    • (1997) J Neurochem , vol.69 , pp. 1601-1611
    • Pike, C.J.1    Ramezan-Arab, N.2    Cotman, C.W.3
  • 40
    • 16644382257 scopus 로고    scopus 로고
    • Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
    • Storkebaum ED, Lambrechts M, Dewerchin MP, et al. Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS. Nat Neurosci 2005;8:85-92.
    • (2005) Nat Neurosci , vol.8 , pp. 85-92
    • Storkebaum, E.D.1    Lambrechts, M.2    Dewerchin, M.P.3
  • 41
    • 0034741266 scopus 로고    scopus 로고
    • Secreted Aβ does not mediate neurotoxicity by antibody-stimulated amyloid precursor protein
    • Sudo H, Hashimoto Y, Niikura T, et al. Secreted Aβ does not mediate neurotoxicity by antibody-stimulated amyloid precursor protein. Biochem Biophys Res Commun 2001;282:548-556.
    • (2001) Biochem Biophys Res Commun , vol.282 , pp. 548-556
    • Sudo, H.1    Hashimoto, Y.2    Niikura, T.3
  • 42
    • 20144387217 scopus 로고    scopus 로고
    • A humanin derivative, S14G-HN, prevents amyloid-beta-induced memory impairment in mice
    • Tajima H, Kawasumi M, Chiba T, et al. A humanin derivative, S14G-HN, prevents amyloid-beta-induced memory impairment in mice. J Neurosci Res 2005;79:714-723.
    • (2005) J Neurosci Res , vol.79 , pp. 714-723
    • Tajima, H.1    Kawasumi, M.2    Chiba, T.3
  • 43
    • 12444261796 scopus 로고    scopus 로고
    • Two serine residues distinctly regulate the rescue function of humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: Functional potentiation by isomerization and dimerization
    • Terashita K, Hashimoto Y, Niikura T, et al. Two serine residues distinctly regulate the rescue function of humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: Functional potentiation by isomerization and dimerization. J Neurochem 2003;85:1521-1538.
    • (2003) J Neurochem , vol.85 , pp. 1521-1538
    • Terashita, K.1    Hashimoto, Y.2    Niikura, T.3
  • 44
    • 0042839610 scopus 로고    scopus 로고
    • Characterization of the toxic mechanism triggered by Alzheimer's amyloid-β peptides via p75 neurotrophin receptor in neuronal hybrid cells
    • Tsukamoto E, Hashimoto Y, Kanekura K, Niikura T, Aiso S, Nishimoto I. Characterization of the toxic mechanism triggered by Alzheimer's amyloid-β peptides via p75 neurotrophin receptor in neuronal hybrid cells. J Neurosci Res 2003;73:627-636.
    • (2003) J Neurosci Res , vol.73 , pp. 627-636
    • Tsukamoto, E.1    Hashimoto, Y.2    Kanekura, K.3    Niikura, T.4    Aiso, S.5    Nishimoto, I.6
  • 47
    • 10544224542 scopus 로고    scopus 로고
    • Participation of presenilin 2 in apoptosis: Enhanced basal activity conferred by an Alzheimer mutation
    • Wolozin B, Iwasaki K, Vito P, et al. Participation of presenilin 2 in apoptosis: Enhanced basal activity conferred by an Alzheimer mutation. Science 1996;274:1710-1713.
    • (1996) Science , vol.274 , pp. 1710-1713
    • Wolozin, B.1    Iwasaki, K.2    Vito, P.3
  • 48
    • 0013056674 scopus 로고    scopus 로고
    • Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer's disease-relevant insults
    • Yamagishi Y, Hashimoto Y, Niikura T, Nishimoto I. Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer's disease-relevant insults. Peptides 2003;24:585-595.
    • (2003) Peptides , vol.24 , pp. 585-595
    • Yamagishi, Y.1    Hashimoto, Y.2    Niikura, T.3    Nishimoto, I.4
  • 49
    • 15844386159 scopus 로고    scopus 로고
    • G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP
    • Yamatsuji T, Matsui T, Okamoto T, et al. G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP. Science 1996;272:1349-1352.
    • (1996) Science , vol.272 , pp. 1349-1352
    • Yamatsuji, T.1    Matsui, T.2    Okamoto, T.3
  • 50
    • 0030042249 scopus 로고    scopus 로고
    • Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype
    • Yamatsuji T, Okamoto T, Takeda S, Murayama Y, Tanaka N, Nishimoto I. Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype. EMBO J 1996;15:498-509.
    • (1996) EMBO J , vol.15 , pp. 498-509
    • Yamatsuji, T.1    Okamoto, T.2    Takeda, S.3    Murayama, Y.4    Tanaka, N.5    Nishimoto, I.6
  • 51
    • 0034785509 scopus 로고    scopus 로고
    • The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
    • Yang Y, Hentati A, Deng HX, et al. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nat Genet 2001;29: 160-165.
    • (2001) Nat Genet , vol.29 , pp. 160-165
    • Yang, Y.1    Hentati, A.2    Deng, H.X.3
  • 53
    • 2442705358 scopus 로고    scopus 로고
    • Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor
    • Ying G, Iribarren P, Zhou Y, et al. Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor. J Immunol 2004;172:7078-7085.
    • (2004) J Immunol , vol.172 , pp. 7078-7085
    • Ying, G.1    Iribarren, P.2    Zhou, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.