Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer's disease-relevant insults

Peptides

Volumn 24, Issue 4, 2003, Pages 585-595

  Yamagishi, Yohichi ^a   Hashimoto, Yuichi ^a   Niikura, Takako ^a   Nishimoto, Ikuo ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Core domain; Dimerization; Humanin; Neuronal death; Rescue factor; Secretion; Secretion defective mutant; Signal peptide; Structure function relationship

Indexed keywords

ALANINE; ARGININE; CYSTEINE; HUMANIN; LEUCINE; PEPTIDE; PROLINE; SERINE; SIGNAL PEPTIDE; THREONINE; UNCLASSIFIED DRUG; VALINE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACID SYNTHESIS; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIMERIZATION; EMBRYO; INTRACELLULAR SPACE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RAT; STRUCTURE ACTIVITY RELATION;

EID: 0013056674     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(03)00106-2     Document Type: Article

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