Cell death in pancreatitis: Effects of alcohol

Journal of Gastroenterology and Hepatology (Australia)

Volumn 21, Issue SUPPL. 3, 2006, Pages

  Gukovskaya, Anna S ^a,b   Mareninova, Olga A ^a   Odinokova, Irina V ^a   Sung, Kai Feng ^a   Lugea, Aurelia ^a   Fischer, Lars ^a   Wang, Yan Ling ^a   Gukovsky, Ilya ^a   Pandol, Stephen J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

Alcoholic pancreatitis; Caspases; Cytochrome c release; RIP; XIAP

Indexed keywords

ALCOHOL; CASPASE 10; CASPASE 3; CASPASE 8; CASPASE 9; CHOLECYSTOKININ OCTAPEPTIDE; CYTOCHROME C; DNA FRAGMENT; PHOSPHOTRANSFERASE; X LINKED INHIBITOR OF APOPTOSIS;

ALCOHOL ABUSE; ALCOHOL CONSUMPTION; APOPTOSIS; CELL DEATH; CONFERENCE PAPER; CORRELATION ANALYSIS; DISEASE MODEL; DISEASE SEVERITY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; NONHUMAN; PANCREATITIS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

EID: 33747610948     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2006.04571.x     Document Type: Conference Paper

References (52)

1. Assuncao GC, Linden R. Programmed cell deaths. Apoptosis and alternative deathstyles. Eur. J. Biochem. 2004; 271: 1638-50.
2. Edinger AL, Thompson CB. Death by design: apoptosis, necrosis and autophagy. Curr. Opin. Cell Biol. 2004; 16: 663-9.
3. Fiers W, Beyaert R, Declercq W, Vandenabeele P. More than one way to die: apoptosis, necrosis and reactive oxygen damage. Oncogene 1999; 18: 7719-30.
4. Leist M, Jaattela M. Four deaths and a funeral: from caspases to alternative mechanisms. Nat. Rev. Mol. Cell Biol. 2001; 2: 589-98.
5. Proskuryakov SY, Konoplyannikov AG, Gabai VL. Necrosis: a specific form of programmed cell death? Exp. Cell Res. 2003; 283: 1-16.
6. Reed JC, Doctor KS, Godzik A. The domains of apoptosis: a genomics perspective. Sci. STKE 2004; 239: 9-12.
7. Lee HC, Wei YH. Mitochondrial role in life and death of the cell. J. Biomed. Sci. 2000; 7: 2-15.
8. Scaffidi C, Fulda S, Srinivasan A et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 1998; 17: 1675-87.
9. Wolf BB, Green DR. Suicidal tendencies: apoptotic cell death by caspase family proteinases. J. Biol. Chem. 1999; 274: 20 049-52.
10. Bratton SB, Walker G, Srinivasula SM et al. Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes. EMBO J. 2001; 20: 998-1009.
11. Bratton SB, Lewis J, Butterworth M, Duckett CS, Cohen GM. XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis. Cell Death Differ. 2002; 9: 881-92.
12. Salvesen GS, Duckett CS. IAP proteins: blocking the road to death's door. Nat. Rev. Mol. Cell Biol. 2002; 3: 401-10.
13. Adams JM. Ways of dying: multiple pathways to apoptosis. Genes Dev. 2003; 17: 2481-95.
14. Jaattela M, Tschopp J. Caspase-independent cell death in T lymphocytes. Nat. Immunol. 2003; 4: 416-23.
15. Schultz DR, Harrington WJ Jr. Apoptosis: programmed cell death at a molecular level. Semin. Arthritis Rheum. 2003; 32: 345-69.
16. Chan FK, Shisler J, Bixby JG et al. A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J. Biol. Chem. 2003; 278: 51 613-21.
17. Holler N, Zaru R, Micheau O et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat. Immunol. 2000; 1: 489-95.
18. Lin Y, Choksi S, Shen HM et al. Tumor necrosis factor-induced non-apoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation. J. Biol. Chem. 2004; 279: 10822-8.
19. Topanzian M, Gorelick FS. Acute pacreatitis. In: Yamada T, Alpers DHLL, Owyang C, Powell DW, eds. Textbook of Gastroenterology. Philadelphia: Lippincott Williams & Wilkins, 2003; 2026-60.
20. Gukovskaya AS, Perkins P, Zaninovic V et al. Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat. Gastroenterology 1996; 110: 875-84.
21. Kaiser AM, Saluja AK, Sengupta A, Saluja M, Steer ML. Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis. Am. J. Physiol. 1995; 269: C1295-C1304.
22. Saluja A, Hofbauer B, Yamaguchi Y, Yamanaka K, Steer M. Induction of apoptosis reduces the severity of caerulein-induced pancreatitis in mice. Biochem. Biophys. Res. Commun. 1996; 220: 875-8.
23. Sandoval D, Gukovskaya A, Reavey P et al. The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis. Gastroenterology 1996; 111: 1081-91.
24. Bhatia M, Wallig MA, Hofbauer B et al. Induction of apoptosis in pancreatic acinar cells reduces the severity of acute pancreatitis. Biochem. Biophys. Res. Commun. 1998; 246: 476-83.
25. Bhatia M. Apoptosis versus necrosis in acute pancreatitis. Am. J. Physiol. Gastrointest. Liver Physiol. 2004; 286: G189-G196.
26. Gukovskaya AS, Pandol SJ. Cell death pathways in pancreatitis and pancreatic cancer. Pancreatology 2004; 4: 567-86.
27. Bhatia M, Brady M, Shokuhi S, Christmas S, Neoptolemos JP, Slavin J. Inflammatory mediators in acute pancreatitis. J. Pathol. 2000; 190: 117-25.
28. Gukovsky I, Gukovskaya AS, Blinman TA, Zaninovic V, Pandol SJ. Early NF-kappaB activation is associated with hormone-induced pancreatitis. Am. J. Physiol. 1998; 275: G1402-14.
29. Norman JG. New approaches to acute pancreatitis: role of inflammatory mediators. Digestion 1999; 60 (Suppl. 1): 57-60.
30. Steer ML. Early events in acute pancreatitis. Baillieres Best Pract. Res. Clin. Gastroenterol. 1999; 13: 213-25.
31. Gorelick FS, Adler G, Kern HF. Cerulein-induced pancreatitis. In: Go VW, DiMagno EP, Gardner JD, Lebenthal E, Reber HA, Scheele GA, eds. The Pancreas: Biology, Pathology, and Disease, 2nd edn. New York: Raven, 1993; 501-26.
32. Mareninova OA, Sung KF, Hong P et al. Cell death in pancreatitis: caspases protect from necrotizing pancreatitis. J. Biol. Chem. 2006; 281: 3370-81.
33. Ekert PG, Silke J, Vaux DL. Caspase inhibitors. Cell Death Differ. 1999; 6: 1081-6.
34. Nikolovska-Coleska Z, Xu L, Hu Z et al. Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database. J. Med. Chem. 2004; 47: 2430-40.
35. MacFarlane M, Merrison W, Bratton SB, Cohen GM. Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro. J. Biol. Chem. 2002; 277: 36 611-16.
36. Gukovskaya AS, Gukovsky I, Jung Y, Mouria M, Pandol SJ. Cholecystokinin induces caspase activation and mitochondrial dysfunction in pancreatic acinar cells. Roles in cell injury processes of pancreatitis. J. Biol. Chem. 2002; 277: 22 595-604.
37. Bubici C, Papa S, Pham CG, Zazzeroni F, Franzoso G. NF-kappaB and JNK: an intricate affair. Cell Cycle 2004; 3: 1524-9.
38. Datta SR, Brunet A, Greenberg ME. Cellular survival: a play in three Akts. Genes Dev. 1999; 13: 2905-27.
39. Hagemann C, Blank JL. The ups and downs of MEK kinase interactions. Cell. Signal. 2001; 13: 863-75.
40. Fischer L, Lugea A, Shahsahebi M et al. Diverse roles of class I PI3K isoforms delta and gamma in cerulein-induced pancreatitis. Gastroenterology 2006; 130: A72.
41. Gukovsky I, Cheng JH, Nam KJ et al. Phosphatidylinositide 3-kinase gamma regulates key pathologic responses to cholecystokinin in pancreatic acinar cells. Gastroenterology 2004; 126: 554-66.
42. Lupia E, Goffi A, De Giuli P et al. Ablation of phosphoinositide 3-kinase-gamma reduces the severity of acute pancreatitis. Am. J. Pathol. 2004; 165: 2003-11.
43. Singh VP, Saluja AK, Bhagat L et al. Phosphatidylinositol 3-kinase-dependent activation of trypsinogen modulates the severity of acute pancreatitis. J. Clin. Invest. 2001; 108: 1387-95.
44. Cantrell DA. Phosphoinositide 3-kinase signalling pathways. J. Cell Sci. 2001; 114: 1439-45.
45. Dan HC, Sun M, Kaneko S et al. Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP). J. Biol. Chem. 2004; 279: 5405-12.
46. Mareninova OA, Lugea A, Odinokova IV et al. Ethanol stimulates Akt phosphorylation in the pancreas through PTEN oxidation: a predisposing factor in alcoholic pancreatitis? Gastroenterology 2006; 130: A384.
47. Adachi M, Higuchi H, Miura S et al. Bax interacts with the voltage-dependent anion channel and mediates ethanol-induced apoptosis in rat hepatocytes. Am. J. Physiol. Gastrointest. Liver Physiol. 2004; 287: G695-705.
48. Deaciuc IV, D'Souza NB, Burikhanov R et al. Alcohol, but not lipopolysaccharide-induced liver apoptosis involves changes in intracellular compartmentalization of apoptotic regulators. Alcohol. Clin. Exp. Res. 2004; 28: 160-72.
49. Liu J. Fas-mediated signaling pathway in ethanol-induced liver apoptosis: inhibition by zinc. Exp. Biol. Med. (Maywood) 2004; 229: 365-6.
50. Ramachandran V, Watts LT, Maffi SK, Chen J, Schenker S, Henderson G. Ethanol-induced oxidative stress precedes mitochondrially mediated apoptotic death of cultured fetal cortical neurons. J. Neurosci. Res. 2003; 74: 577-88.
51. Fortunato F, Deng X, Gates LK et al. Pancreatic response to endotoxin after chronic alcohol exposure: switch from apoptosis to necrosis? Am. J. Physiol. Gastrointest. Liver Physiol. 2006; 290: G232-G241.
52. Wang YL, Hu R, Lugea A et al. Ethanol feeding alters death signaling in the pancreas. Pancreas 2006; 32: 351-9.