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Volumn 84, Issue 1, 2006, Pages 150-155

Iron absorption by healthy women is not associated with either serum or urinary prohepcidin

Author keywords

Hepcidin; Iron absorption; Iron status; Postmenopausal women; Prohepcidin; Serum ferritin

Indexed keywords

FERRITIN; HEMOGLOBIN; HEPCIDIN; IRON; PROTEIN PRECURSOR; PROTEIN PROHEPCIDIN; TRANSFERRIN; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; IRON DERIVATIVE;

EID: 33747406251     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/84.1.150     Document Type: Article
Times cited : (47)

References (44)
  • 1
    • 0035896581 scopus 로고    scopus 로고
    • A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
    • Pigeon C, Ilyin G, Courselaud B, et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 2001;276:7811-9.
    • (2001) J Biol Chem , vol.276 , pp. 7811-7819
    • Pigeon, C.1    Ilyin, G.2    Courselaud, B.3
  • 2
    • 0037847496 scopus 로고    scopus 로고
    • Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis
    • Nicolas G, Viatte L, Lou DQ, et al. Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis. Nat Genet 2003;34:97-101.
    • (2003) Nat Genet , vol.34 , pp. 97-101
    • Nicolas, G.1    Viatte, L.2    Lou, D.Q.3
  • 3
    • 0037007064 scopus 로고    scopus 로고
    • Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
    • Nicolas G, Bennoun M, Porteu A, et al. Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci U S A 2002;99:4596-601.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 4596-4601
    • Nicolas, G.1    Bennoun, M.2    Porteu, A.3
  • 4
    • 0035902605 scopus 로고    scopus 로고
    • Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
    • Nicolas G, Bennoun M, Devaux I, et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci U S A 2001;98:8780-5.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 8780-8785
    • Nicolas, G.1    Bennoun, M.2    Devaux, I.3
  • 5
    • 0036791486 scopus 로고    scopus 로고
    • The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
    • Nicolas G, Chauvet C, Viatte L, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 2002;110:1037-44.
    • (2002) J Clin Invest , vol.110 , pp. 1037-1044
    • Nicolas, G.1    Chauvet, C.2    Viatte, L.3
  • 6
    • 2042491616 scopus 로고    scopus 로고
    • Effect of hepcidin on intestinal iron absorption in mice
    • Laftah AH, Ramesh B, Simpson RJ, et al. Effect of hepcidin on intestinal iron absorption in mice. Blood 2004;103:3940-4.
    • (2004) Blood , vol.103 , pp. 3940-3944
    • Laftah, A.H.1    Ramesh, B.2    Simpson, R.J.3
  • 7
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E, Tuttle MS, Powelson J, et al. Hepcidin regulates iron efflux by binding to ferroportin and inducing its internalization. Science 2004;306:2051-3.
    • (2004) Science , vol.306 , pp. 2051-2053
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3
  • 8
    • 1342322891 scopus 로고    scopus 로고
    • Hepcidin regulation of ferroportin 1 expression in the liver and intestine of the rat
    • Yeh KY, Yeh M, Glass J. Hepcidin regulation of ferroportin 1 expression in the liver and intestine of the rat. Am J Physiol Gastrointest Liver Physiol 2004;286:G385-94.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.286
    • Yeh, K.Y.1    Yeh, M.2    Glass, J.3
  • 9
    • 0036727925 scopus 로고    scopus 로고
    • Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats
    • Frazer DM, Wilkins SJ, Becker EM, et al. Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats. Gastroenterology 2002;123:835-44.
    • (2002) Gastroenterology , vol.123 , pp. 835-844
    • Frazer, D.M.1    Wilkins, S.J.2    Becker, E.M.3
  • 10
    • 0034284595 scopus 로고    scopus 로고
    • LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity
    • Krause A, Neitz S, Magert HJ, et al. LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. FEBS Lett 2000;480:147-50.
    • (2000) FEBS Lett , vol.480 , pp. 147-150
    • Krause, A.1    Neitz, S.2    Magert, H.J.3
  • 11
    • 0035896642 scopus 로고    scopus 로고
    • Hepcidin, a urinary antimicrobial peptide synthesized in the liver
    • Park CH, Valore EV, Waring AJ, Ganz T. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 2001;276:7806-10.
    • (2001) J Biol Chem , vol.276 , pp. 7806-7810
    • Park, C.H.1    Valore, E.V.2    Waring, A.J.3    Ganz, T.4
  • 12
    • 0842263988 scopus 로고    scopus 로고
    • Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes
    • Zhang AS, Xiong S, Tsukamoto H, Enns CA. Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes. Blood 2004;103:1509-14.
    • (2004) Blood , vol.103 , pp. 1509-1514
    • Zhang, A.S.1    Xiong, S.2    Tsukamoto, H.3    Enns, C.A.4
  • 13
    • 2342422913 scopus 로고    scopus 로고
    • Pro-hepcidin: Expression and cell specific localisation in the liver and its regulation in hereditary haemochromatosis, chronic renal insufficiency, and renal anaemia
    • Kulaksiz H, Gehrke SG, Janetzko A, et al. Pro-hepcidin: expression and cell specific localisation in the liver and its regulation in hereditary haemochromatosis, chronic renal insufficiency, and renal anaemia. Gut 2004;53:735-43.
    • (2004) Gut , vol.53 , pp. 735-743
    • Kulaksiz, H.1    Gehrke, S.G.2    Janetzko, A.3
  • 14
    • 14844291392 scopus 로고    scopus 로고
    • The iron-regulatory peptide hormone hepcidin: Expression and cellular localization in the mammalian kidney
    • Kulaksiz H, Theilig F, Bachmann S, et al. The iron-regulatory peptide hormone hepcidin: expression and cellular localization in the mammalian kidney. J Endocrinol 2005;184:361-70.
    • (2005) J Endocrinol , vol.184 , pp. 361-370
    • Kulaksiz, H.1    Theilig, F.2    Bachmann, S.3
  • 15
    • 0034086884 scopus 로고    scopus 로고
    • Perquisite spin-off from twenty-two years of measuring background in the whole body counter steel room
    • Lykken GI, Ong HS, Alkhatib HA, Harris TR, Momcilovc B, Penland JG. Perquisite spin-off from twenty-two years of measuring background in the whole body counter steel room. Ann NY Acad Sci 2000;904:267-70.
    • (2000) Ann NY Acad Sci , vol.904 , pp. 267-270
    • Lykken, G.I.1    Ong, H.S.2    Alkhatib, H.A.3    Harris, T.R.4    Momcilovc, B.5    Penland, J.G.6
  • 16
    • 0037866396 scopus 로고    scopus 로고
    • The quantitative assessment of body iron
    • Cook JD, Flowers CH, Skikne BS. The quantitative assessment of body iron. Blood 2003;101:3359-64.
    • (2003) Blood , vol.101 , pp. 3359-3364
    • Cook, J.D.1    Flowers, C.H.2    Skikne, B.S.3
  • 17
    • 0035141379 scopus 로고    scopus 로고
    • Soluble transferrin receptor (sTfR) concentration quantified using 2 sTfR kits: Analytical and clinical performance characteristics
    • Wians FH, Urban JE, Kroft SH, Keffer JH. Soluble transferrin receptor (sTfR) concentration quantified using 2 sTfR kits: analytical and clinical performance characteristics. Clin Chim Acta 2001;303:75-81.
    • (2001) Clin Chim Acta , vol.303 , pp. 75-81
    • Wians, F.H.1    Urban, J.E.2    Kroft, S.H.3    Keffer, J.H.4
  • 18
    • 0015921296 scopus 로고
    • Determination of serum creatinine by a direct colorimetric method
    • Heinegard D, Tiderstrom G. Determination of serum creatinine by a direct colorimetric method. Clin Chim Acta 1973;43:305-10.
    • (1973) Clin Chim Acta , vol.43 , pp. 305-310
    • Heinegard, D.1    Tiderstrom, G.2
  • 20
    • 0002938727 scopus 로고
    • Intestinal iron absorption in man. Methods of measurement, dose-relationship, diagnostic and therapeutic applications
    • Hallberg L, Harwerth HG, Vanotti A, eds. London-New York: Academic Press
    • Heinrich HC. Intestinal iron absorption in man. Methods of measurement, dose-relationship, diagnostic and therapeutic applications. In: Hallberg L, Harwerth HG, Vanotti A, eds. Iron deficiency, pathogenesis, clinical aspects, and therapy. London-New York: Academic Press, 1970;213-94.
    • (1970) Iron Deficiency, Pathogenesis, Clinical Aspects, and Therapy , pp. 213-294
    • Heinrich, H.C.1
  • 21
    • 33646231688 scopus 로고
    • Relationship between the dose administered and the intestinal absorption of iron from ferrous sulphate in humans
    • Satlman P, Hegenauer J, eds. New York, NY: Elsevier Medical
    • Werner E, Roth P, Kaltwasser JP. Relationship between the dose administered and the intestinal absorption of iron from ferrous sulphate in humans. In: Satlman P, Hegenauer J, eds. The biochemistry and physiology of iron. New York, NY: Elsevier Medical, 1982:821-3.
    • (1982) The Biochemistry and Physiology of Iron , pp. 821-823
    • Werner, E.1    Roth, P.2    Kaltwasser, J.P.3
  • 23
    • 0037174609 scopus 로고    scopus 로고
    • C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism
    • Courselaud B, Pigeon C, Inoue Y, et al. C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism. J Biol Chem 2002;277:41163-70.
    • (2002) J Biol Chem , vol.277 , pp. 41163-41170
    • Courselaud, B.1    Pigeon, C.2    Inoue, Y.3
  • 24
    • 4644301624 scopus 로고    scopus 로고
    • Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis
    • Frazer DM, Inglis HR, Wilkins SJ, et al. Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis. Gut 2004;53:1509-15.
    • (2004) Gut , vol.53 , pp. 1509-1515
    • Frazer, D.M.1    Inglis, H.R.2    Wilkins, S.J.3
  • 25
    • 0037111732 scopus 로고    scopus 로고
    • Inappropriate expression of hepcidin is associated with iron refractory anemia: Implications for the anemia of chronic disease
    • Weinstein DA, Roy CN, Fleming MD, Loda MF, Wolfsdorf JI, Andrews NC. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood 2002;100:3776-81.
    • (2002) Blood , vol.100 , pp. 3776-3781
    • Weinstein, D.A.1    Roy, C.N.2    Fleming, M.D.3    Loda, M.F.4    Wolfsdorf, J.I.5    Andrews, N.C.6
  • 26
  • 27
    • 0033958199 scopus 로고    scopus 로고
    • Adaptation of iron absorption in men consuming diets with high or low iron bioavailability
    • Hunt JR, Roughead ZK. Adaptation of iron absorption in men consuming diets with high or low iron bioavailability. Am J Clin Nutr 2000;71:94-102.
    • (2000) Am J Clin Nutr , vol.71 , pp. 94-102
    • Hunt, J.R.1    Roughead, Z.K.2
  • 28
    • 5144232051 scopus 로고    scopus 로고
    • Iron absorption by heterozygous carriers of the HFE C282Y mutation associated with hemochromatosis
    • Hunt JR, Zeng H. Iron absorption by heterozygous carriers of the HFE C282Y mutation associated with hemochromatosis. Am J Clin Nutr 2004;80:924-31.
    • (2004) Am J Clin Nutr , vol.80 , pp. 924-931
    • Hunt, J.R.1    Zeng, H.2
  • 29
    • 23944502314 scopus 로고    scopus 로고
    • Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS
    • Kemna EH, Pickkers P, Nemeth E, van der Hoeven H, Swinkels D. Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS. Blood 2005;106:1864-6.
    • (2005) Blood , vol.106 , pp. 1864-1866
    • Kemna, E.H.1    Pickkers, P.2    Nemeth, E.3    Van Der Hoeven, H.4    Swinkels, D.5
  • 30
    • 22144484497 scopus 로고    scopus 로고
    • Hepcidin levels in humans are correlated with hepatic iron stores, hemoglobin levels, and hepatic function
    • Detivaud L, Nemeth E, Boudjema K, et al. Hepcidin levels in humans are correlated with hepatic iron stores, hemoglobin levels, and hepatic function. Blood 2005;106:746-8.
    • (2005) Blood , vol.106 , pp. 746-748
    • Detivaud, L.1    Nemeth, E.2    Boudjema, K.3
  • 31
    • 0015804314 scopus 로고
    • Serum ferritin concentration and iron stores in normal subjects
    • Walters GO, Miller FM, Worwood M. Serum ferritin concentration and iron stores in normal subjects. J Clin Pathol 1973;26:770-2.
    • (1973) J Clin Pathol , vol.26 , pp. 770-772
    • Walters, G.O.1    Miller, F.M.2    Worwood, M.3
  • 33
    • 0022974645 scopus 로고
    • Plasma ferritin determination as a diagnostic tool
    • Finch CA, Bellotti V, Stray S, et al. Plasma ferritin determination as a diagnostic tool. West J Med 1986;145:657-63.
    • (1986) West J Med , vol.145 , pp. 657-663
    • Finch, C.A.1    Bellotti, V.2    Stray, S.3
  • 34
    • 0027135215 scopus 로고
    • Screening for iron deficiency: An analysis based on bone-marrow examinations and serum ferritin determinations in a population sample of women
    • Hallberg L, Bengtsson C, Lapidus L, Lindstedt G, Lundberg PA, Hulten L. Screening for iron deficiency: an analysis based on bone-marrow examinations and serum ferritin determinations in a population sample of women. Br J Haematol 1993;85:787-98.
    • (1993) Br J Haematol , vol.85 , pp. 787-798
    • Hallberg, L.1    Bengtsson, C.2    Lapidus, L.3    Lindstedt, G.4    Lundberg, P.A.5    Hulten, L.6
  • 35
    • 0023678979 scopus 로고
    • Relationships among iron absorption, percent saturation of plasma transferrin and serum ferritin concentration in humans
    • Taylor P, Martinez-Torres C, Leets I, Ramirez J, Garcia-Casal MN, Layrisse M. Relationships among iron absorption, percent saturation of plasma transferrin and serum ferritin concentration in humans. J Nutr 1988;118:1110-5.
    • (1988) J Nutr , vol.118 , pp. 1110-1115
    • Taylor, P.1    Martinez-Torres, C.2    Leets, I.3    Ramirez, J.4    Garcia-Casal, M.N.5    Layrisse, M.6
  • 36
    • 0024446959 scopus 로고
    • Food iron absorption in idiopathic hemochromatosis
    • Lynch SR, Skikne BS, Cook JD. Food iron absorption in idiopathic hemochromatosis. Blood 1989;74:2187-93.
    • (1989) Blood , vol.74 , pp. 2187-2193
    • Lynch, S.R.1    Skikne, B.S.2    Cook, J.D.3
  • 37
    • 0030743156 scopus 로고    scopus 로고
    • Iron absorption from the whole diet in men: How effective is the regulation of iron absorption?
    • Hallberg L, Hulten L, Gramatkovski E. Iron absorption from the whole diet in men: how effective is the regulation of iron absorption? Am J Clin Nutr 1997;66:347-56.
    • (1997) Am J Clin Nutr , vol.66 , pp. 347-356
    • Hallberg, L.1    Hulten, L.2    Gramatkovski, E.3
  • 38
    • 0033801703 scopus 로고    scopus 로고
    • Adaptation in iron absorption: Iron supplementation reduces nonheme-iron but not heme-iron absorption from food
    • Roughead ZK, Hunt JR. Adaptation in iron absorption: iron supplementation reduces nonheme-iron but not heme-iron absorption from food. Am J Clin Nutr 2000;72:982-9.
    • (2000) Am J Clin Nutr , vol.72 , pp. 982-989
    • Roughead, Z.K.1    Hunt, J.R.2
  • 39
    • 24344462594 scopus 로고    scopus 로고
    • Iron stores modulate hepatic hepcidin expression by an HFE-independent pathway
    • Gehrke SG, Herrmann T, Kulaksiz H, et al. Iron stores modulate hepatic hepcidin expression by an HFE-independent pathway. Digestion 2005;72:25-32.
    • (2005) Digestion , vol.72 , pp. 25-32
    • Gehrke, S.G.1    Herrmann, T.2    Kulaksiz, H.3
  • 40
    • 32644437864 scopus 로고    scopus 로고
    • Iron metabolism in the hemoglobin deficit mouse: Correlation of diferric transferrin with hepcidin expression
    • Wilkins SJ, Frazer DM, Millard KN, McLaren GD, Anderson GJ. Iron metabolism in the hemoglobin deficit mouse: correlation of diferric transferrin with hepcidin expression. Blood 2005;107:1659-64.
    • (2005) Blood , vol.107 , pp. 1659-1664
    • Wilkins, S.J.1    Frazer, D.M.2    Millard, K.N.3    McLaren, G.D.4    Anderson, G.J.5
  • 41
    • 0037564038 scopus 로고    scopus 로고
    • Expression of hepcidin in hereditary hemochromatosis: Evidence for a regulation in response to the serum transferrin saturation and to non-transferrin-bound iron
    • Gehrke SG, Kulaksiz H, Herrmann T, et al. Expression of hepcidin in hereditary hemochromatosis: evidence for a regulation in response to the serum transferrin saturation and to non-transferrin-bound iron. Blood 2003;102:371-6.
    • (2003) Blood , vol.102 , pp. 371-376
    • Gehrke, S.G.1    Kulaksiz, H.2    Herrmann, T.3
  • 42
    • 2942554825 scopus 로고    scopus 로고
    • HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface
    • Giannetti AM, Bjorkman PJ. HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface. J Biol Chem 2004;279:25866-75.
    • (2004) J Biol Chem , vol.279 , pp. 25866-25875
    • Giannetti, A.M.1    Bjorkman, P.J.2
  • 43
    • 0037006654 scopus 로고    scopus 로고
    • Role of HFE in iron metabolism, hereditary haemochromatosis, anaemia of chronic disease, and secondary iron overload
    • Townsend A, Drakesmith H. Role of HFE in iron metabolism, hereditary haemochromatosis, anaemia of chronic disease, and secondary iron overload. Lancet 2002;359:786-90.
    • (2002) Lancet , vol.359 , pp. 786-790
    • Townsend, A.1    Drakesmith, H.2
  • 44
    • 0037962795 scopus 로고    scopus 로고
    • The orchestration of body iron intake: How and where do enterocytes receive their cues?
    • Frazer DM, Anderson GJ. The orchestration of body iron intake: how and where do enterocytes receive their cues? Blood Cells Mol Dis 2003;30:288-97.
    • (2003) Blood Cells Mol Dis , vol.30 , pp. 288-297
    • Frazer, D.M.1    Anderson, G.J.2


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