An Isoquinolinium Derivative Selectively Inhibits MAPK Spc1 of the Stress-Activated MAPK Cascade of Schizosaccharomyces pombe

Chemistry and Biology

Volumn 13, Issue 8, 2006, Pages 881-889

  Kim, Hyun Jun ^a   Park, Jeong Eun ^a   Jin, Sangwook ^a   Kim, Jung Ho ^b   Song, Kiwon ^a  

^a Yonsei University   (South Korea)

^b Hanwha Corporation   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

HWY 5069; ISOQUINOLINE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE INHIBITOR;

ARTICLE; BINDING SITE; CELL CULTURE; CELL LINE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; PHYSIOLOGY; SCHIZOSACCHAROMYCES; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TIME;

BINDING SITES; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HUMANS; ISOQUINOLINES; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; PROTEIN KINASE INHIBITORS; SCHIZOSACCHAROMYCES; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

MAMMALIA; SCHIZOSACCHAROMYCES POMBE;

EID: 33747365859     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2006.06.012     Document Type: Article

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