Long-chain Acyl-CoA is not primarily increased in myotubes established from type 2 diabetic subjects

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1762, Issue 7, 2006, Pages 666-672

  Just, Malene ^a   Færgeman, Nils J ^b   Knudsen, Jens ^b   Beck Nielsen, Henning ^a   Gaster, Michael ^a  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Acyl CoA; Free fatty acid; Insulin resistance; Myotube; Oleic acid; Palmitic acid; Type 2 diabetes

Indexed keywords

ACYL COENZYME A; FATTY ACID; GLYCOGEN; INSULIN; OLEIC ACID; OLEOYL COENZYME A; PALMITIC ACID; PALMITOYL COENZYME A;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; GLYCOGEN SYNTHESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN RESISTANCE; MYOTUBE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ACYL COENZYME A; BLOOD GLUCOSE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; GLYCOGEN; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INSULIN; MIDDLE AGED; MUSCLE FIBERS; OBESITY; REFERENCE VALUES;

ANIMALIA;

EID: 33746831170     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2006.05.005     Document Type: Article

References (45)

1. Damsbo P., Vaag A., Hother-Nielsen O., and Beck-Nielsen H. Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 34 (1991) 239-245
2. Bogardus C., Lillioja S., Stone K., and Mott D. Correlation between muscle glycogen synthase activity and in vivo insulin action in man. J. Clin. Invest. 73 (1984) 1185-1190
3. Beck-Nielsen H., and Groop L.C. Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus. J. Clin. Invest. 94 (1994) 1714-1721
4. Krssak M., Falk P.K., Dresner A., DiPietro L., Vogel S.M., Rothman D.L., Roden M., and Shulman G.I. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia 42 (1999) 113-116
5. Pan D.A., Lillioja S., Kriketos A.D., Milner M.R., Baur L.A., Bogardus C., Jenkins A.B., and Storlien L.H. Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes 46 (1997) 983-988
6. Perseghin G., Scifo P., De Cobelli F., Pagliato E., Battezzati A., Arcelloni C., Vanzulli A., Testolin G., Pozza G., Del Maschio A., and Luzi L. Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes 48 (1999) 1600-1606
7. Levin K., Daa S.H., Alford F.P., and Beck-Nielsen H. Morphometric documentation of abnormal intramyocellular fat storage and reduced glycogen in obese patients with Type II diabetes. Diabetologia 44 (2001) 824-833
8. Gaster M., Ottosen P.D., Vach W., Christiansen H., Staehr P., Beck-Nielsen H., and Schroder H.D. GLUT4 expression in human muscle fibres is not correlated with intracellular triglyceride (TG) content. Is TG a maker or a marker of insulin resistance?. APMIS 111 (2003) 338-348
9. Phillips D.I., Caddy S., Ilic V., Fielding B.A., Frayn K.N., Borthwick A.C., and Taylor R. Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects. Metabolism 45 (1996) 947-950
10. Goodpaster B.H., Thaete F.L., Simoneau J.A., and Kelley D.E. Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 46 (1997) 1579-1585
11. Kelley D.E., Mokan M., Simoneau J.A., and Mandarino L.J. Interaction between glucose and free fatty acid metabolism in human skeletal muscle. J. Clin. Invest. 92 (1993) 91-98
12. Boden G., Chen X., Ruiz J., White J.V., and Rossetti L. Mechanisms of fattyacid-induced inhibition of glucose uptake. J. Clin. Invest. 93 (1994) 2438-2446
13. Boden G., Jadali F., White J., Liang Y., Mozzoli M., Chen X., Coleman E., and Smith C. Effects of fat on insulin-stimulated carbohydrate metabolism in normal men. J. Clin. Invest. 88 (1991) 960-966
14. Roden M., Price T.B., Perseghin G., Petersen K.F., Rothman D.L., Cline G.W., and Shulman G.I. Mechanism of free fatty acid-induced insulin resistance in humans. J. Clin. Invest. 97 (1996) 2859-2865
15. Kraegen E.W., Clark P.W., Jenkins A.B., Daley E.A., Chisholm D.J., and Storlien L.H. Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats. Diabetes 40 (1991) 1397-1403
16. Oakes N.D., Cooney G.J., Camilleri S., Chisholm D.J., and Kraegen E.W. Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding. Diabetes 46 (1997) 1768-1774
17. Kim J.K., Wi J.K., and Youn J.H. Metabolic impairment precedes insulin resistance in skeletal muscle during high-fat feeding in rats. Diabetes 45 (1996) 651-658
18. Hulver M.W., Berggren J.R., Cortright R.N., Dudek R.W., Thompson R.P., Pories W.J., MacDonald K.G., Cline G.W., Shulman G.I., Dohm G.L., and Houmard J.A. Skeletal muscle lipid metabolism with obesity. Am. J. Physiol Endocrinol. Metab. 284 (2003) E741-E747
19. Ellis B.A., Poynten A., Lowy A.J., Furler S.M., Chisholm D.J., Kraegen E.W., and Cooney G.J. Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle. Am. J. Physiol: Endocrinol. Metab. 279 (2000) E554-E560
20. Faergeman N.J., and Knudsen J. Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling. Biochem. J. 323 Pt. 1 (1997) 1-12
21. Schmitz-Peiffer C. Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply. Cell. Signal. 12 (2000) 583-594
22. Schmitz-Peiffer C., Craig D.L., and Biden T.J. Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate. J. Biol. Chem. 274 (1999) 24202-24210
23. Chavez J.A., and Summers S.A. Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. Arch. Biochem. Biophys. 419 (2003) 101-109
24. Gaster M., Rustan A.C., and Beck-Nielsen H. Differential utilization of saturated palmitate and unsaturated oleate: evidence from cultured myotubes. Diabetes 54 (2005) 648-656
25. Gaster M., Petersen I., Hojlund K., Poulsen P., and Beck-Nielsen H. The diabetic phenotype is conserved in myotubes established from diabetic subjects: evidence for primary defects in glucose transport and glycogen synthase activity. Diabetes 51 (2002) 921-927
26. Gaster M., Rustan A.C., Aas V., and Beck-Nielsen H. Reduced lipid oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin: evidence from cultured myotubes. Diabetes 53 (2004) 542-548
27. Gaster M., and Beck-Nielsen H. The reduced insulin-mediated glucose oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin-evidence from cultured myotubes. Biochim. Biophys. Acta 1690 (2004) 85-91
28. Henry R.R., Ciaraldi T.P., Abrams-Carter L., Mudaliar S., Park K.S., and Nikoulina S.E. Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms. J. Clin. Invest. 98 (1996) 1231-1236
29. Henry R.R., Ciaraldi T.P., Mudaliar S., Abrams L., and Nikoulina S.E. Acquired defects of glycogen synthase activity in cultured human skeletal muscle cells: influence of high glucose and insulin levels. Diabetes 45 (1996) 400-407
30. Gaster M., Kristensen S.R., Beck-Nielsen H., and Schroder H.D. A cellular model system of differentiated human myotubes. APMIS 109 (2001) 735-744
31. Gaster M., Schroder H.D., Handberg A., and Beck-Nielsen H. The basal kinetic parameters of glycogen synthase in human myotube cultures are not affected by chronic high insulin exposure. Biochim. Biophys. Acta 1537 (2001) 211-221
32. Larson T.R., and Graham I.A. Technical advance: a novel technique for the sensitive quantification of acyl CoA esters from plant tissues. Plant J. 25 (2001) 115-125
33. Houmard J.A., Tanner C.J., Yu C., Cunningham P.G., Pories W.J., MacDonald K.G., and Shulman G.I. Effect of weight loss on insulin sensitivity and intramuscular long-chain fatty acyl-CoAs in morbidly obese subjects. Diabetes 51 (2002) 2959-2963
34. Knudsen J., Neergaard T.B., Gaigg B., Jensen M.V., and Hansen J.K. Role of acyl-CoA binding protein in acyl-CoA metabolism and acyl-CoA-mediated cell signaling. J. Nutr. 130 (2000) 294S-298S
35. Chen M.T., Kaufman L.N., Spennetta T., and Shrago E. Effects of high fat-feeding to rats on the interrelationship of body weight, plasma insulin, and fatty acyl-coenzyme A esters in liver and skeletal muscle. Metabolism 41 (1992) 564-569
36. Chalkley S.M., Hettiarachchi M., Chisholm D.J., and Kraegen E.W. Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat. Metabolism 47 (1998) 1121-1126
37. Wilmsen H.M., Ciaraldi T.P., Carter L., Reehman N., Mudaliar S.R., and Henry R.R. Thiazolidinediones upregulate impaired fatty acid uptake in skeletal muscle of type 2 diabetic subjects. Am. J. Physiol: Endocrinol. Metab. 285 2 (2003) E354-E362
38. Ortenblad N., Mogensen M., Petersen I., Hojlund K., Levin K., Sahlin K., Beck-Nielsen H., and Gaster M. Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect. Biochim. Biophys. Acta 1741 (2005) 206-214
39. Gaster M., and Beck-Nielsen H. Triacylglycerol accumulation is not primarily affected in myotubes established from Type 2 diabetic subjects. BBA 1761 (2006) 100-110
40. Chavez J.A., Knotts T.A., Wang L.P., Li G., Dobrowsky R.T., Florant G.L., and Summers S.A. A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. J.Biol.Chem. 278 (2003) 10297-10303
41. Storlien L.H., Kraegen E.W., Chisholm D.J., Ford G.L., Bruce D.G., and Pascoe W.S. Fish oil prevents insulin resistance induced by high-fat feeding in rats. Science 237 (1987) 885-888
42. Storlien L.H., Jenkins A.B., Chisholm D.J., Pascoe W.S., Khouri S., and Kraegen E.W. Influence of dietary fat composition on development of insulin resistance in rats, relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid. Diabetes 40 (1991) 280-289
43. Fuehrlein B.S., Rutenberg M.S., Silver J.N., Warren M.W., Theriaque D.W., Duncan G.E., Stacpoole P.W., and Brantly M.L. Differential metabolic effects of saturated versus polyunsaturated fats in ketogenic diets. J. Clin. Endocrinol. Metab. 89 (2004) 1641-1645
44. Miyazaki M., and Ntambi J.M. Role of stearoyl-coenzyme A desaturase in lipid metabolism. Prostaglandins Leukot. Essent. Fat. Acids 68 (2003) 113-121
45. Ntambi J.M., and Miyazaki M. Regulation of stearoyl-CoA desaturases and role in metabolism. Prog. Lipid Res. 43 (2004) 91-104