Hydrogen peroxide induces vascular permeability via regulation of vascular endothelial growth factor

American Journal of Respiratory Cell and Molecular Biology

Volumn 35, Issue 2, 2006, Pages 190-197

  Lee, Kyung Sun ^a   Kim, So Ri ^a   Park, Seoung Ju ^a   Park, Hee Sun ^a   Min, Kyung Hoon ^a   Lee, Min Hee ^a   Jin, Sun Mi ^a   Jin, Gong Yong ^a   Yoo, Wan Hee ^a   Lee, Yong Chul ^a  

^a Chonbuk National University Medical School   (South Korea)

Author keywords

Airway; Animal model; Hydrogen peroxide; Reactive oxygen species; Vascular endothelial growth factor; Vascular permeability

Indexed keywords

2 METHOXYESTRADIOL; 2 MORPHOLINO 8 PHENYLCHROMONE; 2 OXO 4 THIAZOLIDINECARBOXYLIC ACID; ANTIOXIDANT; HYDROGEN PEROXIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NUCLEAR PROTEIN; OXINDOLE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; THIOCTIC ACID; VASCULOTROPIN; WORTMANNIN;

AIRWAY; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; EXTRAVASATION; FEMALE; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; OXIDATIVE STRESS; REGULATORY MECHANISM; WESTERN BLOTTING;

ANIMALS; CAPILLARY PERMEABILITY; FEMALE; GENE EXPRESSION REGULATION; HYDROGEN PEROXIDE; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; OXIDANTS; SPECIFIC PATHOGEN-FREE ORGANISMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MURINAE;

EID: 33746813191     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2005-0482OC     Document Type: Article

References (41)

1. Henricks PA, Nijkamp FP. Reactive oxygen species as mediators in asthma. Pulm Pharmacol Ther 2001;14:409-420.
2. Repine JE, Bast A, Lankhorst I. Oxidative stress in chronic obstructive pulmonary disease. Oxidative Stress Study Group. Am J Respir Crit Care Med 1997;156:341-357.
3. Kuroki M, Voest EE, Amano S, Beerepoot LV, Takashima S, Tolentino M, Kim RY, Rohan RM, Colby KA, Yeo KT, et al. Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo. J Clin Invest 1996;98:1667-1675.
4. Dvorak HF, Brown LF, Detmar M, Dvorak AM. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995;146:1029-1039.
5. Lee YC, Lee HK. Vascular endothelial growth factor in patients with acute asthma. J Allergy Clin Immunol 2001;107:1106.
6. Lee YC, Kwak YG, Song CH. Contribution of vascular endothelial growth factor to airway hyper-responsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma. J Immunol 2002;168:3595-3600.
7. Wang GL, Semenza GL. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 1995;270:1230-1237.
8. 2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 1999;15:551-578.
9. Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, et al. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 2001;107:43-54.
10. Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, Salic A, Asara JM, Lane WS, Kaelin WG Jr. HIF-1α targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 2001;292:464-468.
11. National Institutes of Health (NIH). Guide for the Care and Use of Laboratory Animals. NIH publication No. 86-23. Revised 1985. US Government Printing Office, Washington, D.C.
12. Han MK, Kim SJ, Park YR, Shin YM, Park HJ, Park KJ, Park KH, Kim HK, Jang SI, An NH, et al. Antidiabetic effect of a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, through CD38 dimerization and internalization. J Biol Chem 2002;277:5315-5321.
13. Zilberberg L, Shinkaruk S, Lequin O, Rousseau B, Hagedorn M, Costa F, Caronzolo D, Balke M, Canron X, Convert O, et al. Structure and inhibitory effects on angiogenesis and tumor development of a new vascular endothelial growth inhibitor. J Biol Chem 2003;278:35564-35573.
14. Tigani B, Hannon JP, Mazzoni L, Fozard JR. Effects of wortmannin on airways inflammation induced by allergen in actively sensitized Brown Norway rats. Eur J Pharmacol 2001;433:217-223.
15. Kwak YG, Song CH, Yi HK, Hwang PH, Kim JS, Lee KS, Lee YC. Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma. J Clin Invest 2003;111:1083-1092.
16. Mabjeesh NJ, Escuin D, La Vallee TM, Pribluda VS, Swartz GM, Johnson MS, Willard MT, Zhong H, Simons JW, Giannakakou P. 2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF. Cancer Cell 2003;3:363-375.
17. Mooberry SL. Mechanism of action of 2-methoxyestradiol: new developments. Drug Resist Updat 2003;6:355-361.
18. 2 for platelet-derived growth factor signal transduction. Science 1995;270:296-299.
19. Lee M, You HJ, Cho SH, Woo CH, Yoo MH, Joe EH, Kim JH. Implication of the small GTPase Rac1 in the generation of reactive oxygen species in response to β-amyloid in C6 astrolgioma cells. Biochem J 2002;366:937-943.
20. Takeda K, Hamelmann E, Joetham A, Shultz LD, Larsen GL, Irvin CG, Gelfand EW. Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice. J Exp Med 1997;186:449-454.
21. McQuaid KE, Keenan AK. Endothelial barrier dysfunction and oxidative stress: roles for nitric oxide? Exp Physiol 1997;82:369-376.
22. Lei YH, Barnes PJ, Rogers DF. Involvement of hydroxyl radicals in neurogenic airway plasma exudation and bronchoconstriction in guinea-pigs in vivo. Br J Pharmacol 1996;117:449-454.
23. Rahman I, Skwarska E, MacNee W. Attenuation of oxidant/antioxi-dant imbalance during treatment of exacerbations of chronic obstructive pulmonary disease. Thorax 1997;52:565-568.
24. Hulsmann AR, Raatgeep HR, den Hollander JC, Stijnen T, Saxena PR, Kerrebijn KF, de Jongste JC. Oxidative epithelial damage produces hyperresponsiveness of human peripheral airways. Am J Respir Crit Care Med 1994;149:519-525.
25. Cortijo J, Marti-Cabrera M, de la Asuncion JG, Pallardo FV, Esteras A, Bruseghini L, Vina J, Morcillo EJ. Contraction of human airways by oxidative stress protection by N-acetylcysteine. Free Radic Biol Med 1999;27:392-400.
26. Adam L, Bouvier M, Jones TL. Nitric oxide modulates beta(2)-adrenergic receptor palmitoylation and signaling. J Biol Chem 1999;274:26337-26343.
27. Lee YC, Lee KS, Park SJ, Park HS, Lim JS, Park KH, Im MJ, Choi IW, Lee HK, Kim UH. Blockade of airway hyperresponsiveness and inflammation in a murine model of asthma by a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid. FASEB J 2004;18:1917-1919.
28. Lee KS, Park HS, Park SJ, Kim SR, Min KH, Jin SM, Park KH, Kim UH, Kim CY, Lee YC. A prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, regulates vascular permeability by reducing vascular endothelial growth factor expression in asthma. Mol Pharmacol 2005;68:1281-1290.
29. Semenza GL. Hypoxia-inducible factor 1: control of oxygen homeostasis in health and disease. Pediatr Res 2001;49:614-617.
30. Hellwig-Burgel T, Stiehl DP, Jelkmann W. Hypoxia-inducible factor-1. In: Lahiri S, Semenza GL, Prabhakar NR, editors. Oxygen sensing. New York: Marcel Dekker, Inc.; 2003. pp. 95-108.
31. Bilton RL, Booker GW. The subtle side to hypoxia-inducible factor (HIFα) regulation. Eur J Biochem 2003;270:791-798.
32. Lukashev D, Caldwell C, Ohta A, Chen P, Sitkovsky M. Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1 alpha in activated T lymphocytes. J Biol Chem 2001;276:48754-48763.
33. Jung YJ, Isaacs JS, Lee S, Trepel J, Neckers L. IL-1beta-mediated upregulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis. FASEB J 2003;17:2115-2117.
34. Laughner E, Taghavi P, Chiles K, Mahon PC, Semenza GL. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol Cell Biol 2001;21:3995-4004.
35. Mottet D, Dumont V, Deccache Y, Demazy C, Ninane N, Raes M, Michiels C. Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells. J Biol Chem 2003;278:31277-31285.
36. Li YM, Zhou BP, Deng J, Pan Y, Hay N, Hung M. A hypoxia independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells. Cancer Res 2005;65:3257-3263.
37. Chandel NS, McClintock DS, Feliciano CE, Wood TM, Melendez JA, Rodriguez AM, Schumacker PT. Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1α during hypoxia. J Biol Chem 2000;275:25130-25138.
38. Haddad JJ, Land SC. A non-hypoxic, ROS-sensitive pathway mediates TNF-alpha-dependent regulation of HIF-lalpha. FEBS J Lett 2001;505:269-274.
39. Cho YS, Lee J, Lee TH, Lee EY, Lee KU, Park JY, Moon HB. α-Lipoic acid inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma. J Allergy Clin Immunol 2004;114:429-435.
40. Van de Graaf EA, Out TA, Roos CM, Jansen HM. Respiratory membrane permeability and bronchial hyperreactivity in patients with stable asthma: effects of therapy with inhaled steroids. Am Rev Respir Dis 1991;143:362-368.
41. Persson CG. Epithelial cells: barrier functions and shedding restitution mechanisms. Am J Respir Crit Care Med 1996;153:S9-S10.