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Volumn 6, Issue 1-2, 2006, Pages 86-96

Motoneurons and CD4+ effector T cell subsets: Neuroprotection and repair

Author keywords

ALS; CD4+T cells; Facial nerve injury; FMN; Neuro immune interactions; Neuroprotection

Indexed keywords

CD4 ANTIGEN; CYTOKINE;

EID: 33746700731     PISSN: 15662772     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cnr.2006.06.001     Document Type: Article
Times cited : (4)

References (100)
  • 1
    • 2942687605 scopus 로고    scopus 로고
    • Elaborate interactions between the immune and nervous systems
    • Steinman L. Elaborate interactions between the immune and nervous systems. Nat Immunol 5 6 (2004) 575-581
    • (2004) Nat Immunol , vol.5 , Issue.6 , pp. 575-581
    • Steinman, L.1
  • 2
    • 0030176406 scopus 로고    scopus 로고
    • Peripheral nerve regeneration
    • Ide C. Peripheral nerve regeneration. Neurosci Res 25 2 (1996) 101-121
    • (1996) Neurosci Res , vol.25 , Issue.2 , pp. 101-121
    • Ide, C.1
  • 4
    • 0041942742 scopus 로고    scopus 로고
    • CD4+T, but not CD8+ or B, lymphocytes mediate facial motoneuron survival after facial nerve transection
    • Serpe C.J., Coers S., Sanders V.M., and Jones K.J. CD4+T, but not CD8+ or B, lymphocytes mediate facial motoneuron survival after facial nerve transection. Brain Behav Immun 17 5 (2003) 393-402
    • (2003) Brain Behav Immun , vol.17 , Issue.5 , pp. 393-402
    • Serpe, C.J.1    Coers, S.2    Sanders, V.M.3    Jones, K.J.4
  • 5
    • 14944352071 scopus 로고    scopus 로고
    • Inflammation and the degenerative diseases of aging
    • McGeer P.L., and McGeer E.G. Inflammation and the degenerative diseases of aging. Ann NY Acad Sci 1035 (2004) 104-116
    • (2004) Ann NY Acad Sci , vol.1035 , pp. 104-116
    • McGeer, P.L.1    McGeer, E.G.2
  • 6
    • 20444466786 scopus 로고    scopus 로고
    • Role of inflammation in neurodegenerative diseases
    • Minghetti L. Role of inflammation in neurodegenerative diseases. Curr Opin Neurol 18 3 (2005) 315-321
    • (2005) Curr Opin Neurol , vol.18 , Issue.3 , pp. 315-321
    • Minghetti, L.1
  • 7
    • 14044272154 scopus 로고    scopus 로고
    • Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats
    • Pannu R., Barbosa E., Singh A.K., and Singh I. Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats. J Neurosci Res 79 3 (2005) 340-350
    • (2005) J Neurosci Res , vol.79 , Issue.3 , pp. 340-350
    • Pannu, R.1    Barbosa, E.2    Singh, A.K.3    Singh, I.4
  • 8
    • 12144254738 scopus 로고    scopus 로고
    • Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration
    • Verma P., Chierzi S., Codd A.M., et al. Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration. J Neurosci 25 2 (2005) 331-342
    • (2005) J Neurosci , vol.25 , Issue.2 , pp. 331-342
    • Verma, P.1    Chierzi, S.2    Codd, A.M.3
  • 9
    • 0026878739 scopus 로고
    • Changes in cytoskeletal protein synthesis following axon injury and during axon regeneration
    • Bisby M.A., and Tetzlaff W. Changes in cytoskeletal protein synthesis following axon injury and during axon regeneration. Mol Neurobiol 6 2-3 (1992) 107-123
    • (1992) Mol Neurobiol , vol.6 , Issue.2-3 , pp. 107-123
    • Bisby, M.A.1    Tetzlaff, W.2
  • 10
    • 4243562216 scopus 로고    scopus 로고
    • Exacerbation of facial motoneuron loss after facial nerve transection in severe combined immunodeficient (scid) mice
    • Serpe C.J., Kohm A.P., Huppenbauer C.B., Sanders V.M., and Jones K.J. Exacerbation of facial motoneuron loss after facial nerve transection in severe combined immunodeficient (scid) mice. J Neurosci 19 11 (1999) RC7
    • (1999) J Neurosci , vol.19 , Issue.11
    • Serpe, C.J.1    Kohm, A.P.2    Huppenbauer, C.B.3    Sanders, V.M.4    Jones, K.J.5
  • 11
    • 0347993165 scopus 로고    scopus 로고
    • Cyclophosphamide modulates CD4+T cells into a T helper type 2 phenotype and reverses increased IFN-γ production of CD8+T cells in secondary progressive multiple sclerosis
    • Karni A., Balashov K., Hancock W.W., et al. Cyclophosphamide modulates CD4+T cells into a T helper type 2 phenotype and reverses increased IFN-γ production of CD8+T cells in secondary progressive multiple sclerosis. J Neuroimmunol 146 1-2 (2004) 189-198
    • (2004) J Neuroimmunol , vol.146 , Issue.1-2 , pp. 189-198
    • Karni, A.1    Balashov, K.2    Hancock, W.W.3
  • 12
    • 0142247577 scopus 로고    scopus 로고
    • Natural killer cells do not mediate facial motoneuron survival after facial nerve transection
    • Byram S.C., Serpe C.J., Pruett S.B., Sanders V.M., and Jones K.J. Natural killer cells do not mediate facial motoneuron survival after facial nerve transection. Brain Behav Immun 17 6 (2003) 417-425
    • (2003) Brain Behav Immun , vol.17 , Issue.6 , pp. 417-425
    • Byram, S.C.1    Serpe, C.J.2    Pruett, S.B.3    Sanders, V.M.4    Jones, K.J.5
  • 13
    • 0015197354 scopus 로고
    • The axon reaction: a review of the principal features of perikaryal responses to axon injury
    • Lieberman A.R. The axon reaction: a review of the principal features of perikaryal responses to axon injury. Int Rev Neurobiol 14 (1971) 49-124
    • (1971) Int Rev Neurobiol , vol.14 , pp. 49-124
    • Lieberman, A.R.1
  • 14
    • 2342606947 scopus 로고    scopus 로고
    • CD4-positive T cell-mediated neuroprotection requires dual compartment antigen presentation
    • Byram S.C., Carson M.J., DeBoy C.A., Serpe C.J., Sanders V.M., and Jones K.J. CD4-positive T cell-mediated neuroprotection requires dual compartment antigen presentation. J Neurosci 24 18 (2004) 4333-4339
    • (2004) J Neurosci , vol.24 , Issue.18 , pp. 4333-4339
    • Byram, S.C.1    Carson, M.J.2    DeBoy, C.A.3    Serpe, C.J.4    Sanders, V.M.5    Jones, K.J.6
  • 15
    • 0025697469 scopus 로고
    • Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo
    • Murphy K.M., Heimberger A.B., and Loh D.Y. Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. Science 250 4988 (1990) 1720-1723
    • (1990) Science , vol.250 , Issue.4988 , pp. 1720-1723
    • Murphy, K.M.1    Heimberger, A.B.2    Loh, D.Y.3
  • 16
    • 0002281608 scopus 로고    scopus 로고
    • Antigen presentation in the central nervous system
    • Keane R.W., and Hickey W.F. (Eds), Oxford University Press, New York
    • Sedgwick J.D., and Hickey W.F. Antigen presentation in the central nervous system. In: Keane R.W., and Hickey W.F. (Eds). Immunology and the Nervous System (1997), Oxford University Press, New York 364
    • (1997) Immunology and the Nervous System , pp. 364
    • Sedgwick, J.D.1    Hickey, W.F.2
  • 17
    • 0023949553 scopus 로고
    • Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo
    • Hickey W.F., and Kimura H. Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science 239 4837 (1988) 290-292
    • (1988) Science , vol.239 , Issue.4837 , pp. 290-292
    • Hickey, W.F.1    Kimura, H.2
  • 18
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann T.R., Cherwinski H., Bond M.W., Giedlin M.A., and Coffman R.L. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 136 7 (1986) 2348-2357
    • (1986) J Immunol , vol.136 , Issue.7 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 19
    • 0035134439 scopus 로고    scopus 로고
    • Type 1/Type 2 immunity in infectious diseases
    • Spellberg B., and Edwards Jr. J.E. Type 1/Type 2 immunity in infectious diseases. Clin Infect Dis 32 1 (2001) 76-102
    • (2001) Clin Infect Dis , vol.32 , Issue.1 , pp. 76-102
    • Spellberg, B.1    Edwards Jr., J.E.2
  • 20
    • 0034442057 scopus 로고    scopus 로고
    • Molecular aspects of T-cell differentiation
    • Rao A., and Avni O. Molecular aspects of T-cell differentiation. Br Med Bull 56 4 (2000) 969-984
    • (2000) Br Med Bull , vol.56 , Issue.4 , pp. 969-984
    • Rao, A.1    Avni, O.2
  • 21
    • 0023726937 scopus 로고
    • Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones
    • Gajewski T.F., and Fitch F.W. Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J Immunol 140 12 (1988) 4245-4252
    • (1988) J Immunol , vol.140 , Issue.12 , pp. 4245-4252
    • Gajewski, T.F.1    Fitch, F.W.2
  • 22
    • 0026648380 scopus 로고
    • Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system
    • Hsieh C.S., Heimberger A.B., Gold J.S., O'Garra A., and Murphy K.M. Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc Natl Acad Sci USA 89 13 (1992) 6065-6069
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.13 , pp. 6065-6069
    • Hsieh, C.S.1    Heimberger, A.B.2    Gold, J.S.3    O'Garra, A.4    Murphy, K.M.5
  • 23
    • 0029937270 scopus 로고    scopus 로고
    • Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
    • Kaplan M.H., Sun Y.L., Hoey T., and Grusby M.J. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382 6587 (1996) 174-177
    • (1996) Nature , vol.382 , Issue.6587 , pp. 174-177
    • Kaplan, M.H.1    Sun, Y.L.2    Hoey, T.3    Grusby, M.J.4
  • 24
    • 0034658501 scopus 로고    scopus 로고
    • The biology of Stat4 and Stat6
    • Wurster A.L., Tanaka T., and Grusby M.J. The biology of Stat4 and Stat6. Oncogene 19 21 (2000) 2577-2584
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2577-2584
    • Wurster, A.L.1    Tanaka, T.2    Grusby, M.J.3
  • 25
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
    • Kaplan M.H., Schindler U., Smiley S.T., and Grusby M.J. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4 3 (1996) 313-319
    • (1996) Immunity , vol.4 , Issue.3 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 26
    • 15844404509 scopus 로고    scopus 로고
    • Essential role of Stat6 in IL-4 signalling
    • Takeda K., Tanaka T., Shi W., et al. Essential role of Stat6 in IL-4 signalling. Nature 380 6575 (1996) 627-630
    • (1996) Nature , vol.380 , Issue.6575 , pp. 627-630
    • Takeda, K.1    Tanaka, T.2    Shi, W.3
  • 27
    • 0024441028 scopus 로고
    • Role of cervical lymph nodes in the systemic humoral immune response to human serum albumin microinfused into rat cerebrospinal fluid
    • Harling-Berg C., Knopf P.M., Merriam J., and Cserr H.F. Role of cervical lymph nodes in the systemic humoral immune response to human serum albumin microinfused into rat cerebrospinal fluid. J Neuroimmunol 25 2-3 (1989) 185-193
    • (1989) J Neuroimmunol , vol.25 , Issue.2-3 , pp. 185-193
    • Harling-Berg, C.1    Knopf, P.M.2    Merriam, J.3    Cserr, H.F.4
  • 28
    • 0027740941 scopus 로고
    • CSF drains directly from the subarachnoid space into nasal lymphatics in the rat. Anatomy, histology and immunological significance
    • Kida S., Pantazis A., and Weller R.O. CSF drains directly from the subarachnoid space into nasal lymphatics in the rat. Anatomy, histology and immunological significance. Neuropathol Appl Neurobiol 19 6 (1993) 480-488
    • (1993) Neuropathol Appl Neurobiol , vol.19 , Issue.6 , pp. 480-488
    • Kida, S.1    Pantazis, A.2    Weller, R.O.3
  • 29
    • 0026567020 scopus 로고
    • Directional and compartmentalised drainage of interstitial fluid and cerebrospinal fluid from the rat brain
    • Zhang E.T., Richards H.K., Kida S., and Weller R.O. Directional and compartmentalised drainage of interstitial fluid and cerebrospinal fluid from the rat brain. Acta Neuropathol (Berl) 83 3 (1992) 233-239
    • (1992) Acta Neuropathol (Berl) , vol.83 , Issue.3 , pp. 233-239
    • Zhang, E.T.1    Richards, H.K.2    Kida, S.3    Weller, R.O.4
  • 30
    • 0029055256 scopus 로고
    • Imaging techniques for in vivo quantitation of extracranial lymphatic drainage of the brain
    • Hunter J.V., Batchelder K.F., Lo E.H., and Wolf G.L. Imaging techniques for in vivo quantitation of extracranial lymphatic drainage of the brain. Neuropathol Appl Neurobiol 21 3 (1995) 185-188
    • (1995) Neuropathol Appl Neurobiol , vol.21 , Issue.3 , pp. 185-188
    • Hunter, J.V.1    Batchelder, K.F.2    Lo, E.H.3    Wolf, G.L.4
  • 31
    • 0029042781 scopus 로고
    • Physiology and immunology of lymphatic drainage of interstitial and cerebrospinal fluid from the brain
    • Knopf P.M., Cserr H.F., Nolan S.C., Wu T.Y., and Harling-Berg C.J. Physiology and immunology of lymphatic drainage of interstitial and cerebrospinal fluid from the brain. Neuropathol Appl Neurobiol 21 3 (1995) 175-180
    • (1995) Neuropathol Appl Neurobiol , vol.21 , Issue.3 , pp. 175-180
    • Knopf, P.M.1    Cserr, H.F.2    Nolan, S.C.3    Wu, T.Y.4    Harling-Berg, C.J.5
  • 32
    • 0026742832 scopus 로고
    • Facial nerve transection causes expansion of myelin autoreactive T cells in regional lymph nodes and T cell homing to the facial nucleus
    • Olsson T., Diener P., Ljungdahl A., Hojeberg B., van der Meide P.H., and Kristensson K. Facial nerve transection causes expansion of myelin autoreactive T cells in regional lymph nodes and T cell homing to the facial nucleus. Autoimmunity 13 2 (1992) 117-126
    • (1992) Autoimmunity , vol.13 , Issue.2 , pp. 117-126
    • Olsson, T.1    Diener, P.2    Ljungdahl, A.3    Hojeberg, B.4    van der Meide, P.H.5    Kristensson, K.6
  • 33
    • 0142075723 scopus 로고    scopus 로고
    • In situ processing and distribution of intracerebrally injected OVA in the CNS
    • Ling C., Sandor M., and Fabry Z. In situ processing and distribution of intracerebrally injected OVA in the CNS. J Neuroimmunol 141 1-2 (2003) 90-98
    • (2003) J Neuroimmunol , vol.141 , Issue.1-2 , pp. 90-98
    • Ling, C.1    Sandor, M.2    Fabry, Z.3
  • 34
    • 0035159473 scopus 로고    scopus 로고
    • IFN-γ production by Th1 cells generated from naive CD4+T cells exposed to norepinephrine
    • Swanson M.A., Lee W.T., and Sanders V.M. IFN-γ production by Th1 cells generated from naive CD4+T cells exposed to norepinephrine. J Immunol 166 1 (2001) 232-240
    • (2001) J Immunol , vol.166 , Issue.1 , pp. 232-240
    • Swanson, M.A.1    Lee, W.T.2    Sanders, V.M.3
  • 35
    • 0031573079 scopus 로고    scopus 로고
    • Activated T helper 1 and T helper 2 cells differentially express the beta-2-adrenergic receptor: a mechanism for selective modulation of T helper 1 cell cytokine production
    • Ramer-Quinn D.S., Baker R.A., and Sanders V.M. Activated T helper 1 and T helper 2 cells differentially express the beta-2-adrenergic receptor: a mechanism for selective modulation of T helper 1 cell cytokine production. J Immunol 159 10 (1997) 4857-4867
    • (1997) J Immunol , vol.159 , Issue.10 , pp. 4857-4867
    • Ramer-Quinn, D.S.1    Baker, R.A.2    Sanders, V.M.3
  • 37
    • 0037083665 scopus 로고    scopus 로고
    • Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4(+) T cells
    • Bajenoff M., Wurtz O., and Guerder S. Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4(+) T cells. J Immunol 168 4 (2002) 1723-1729
    • (2002) J Immunol , vol.168 , Issue.4 , pp. 1723-1729
    • Bajenoff, M.1    Wurtz, O.2    Guerder, S.3
  • 38
    • 0029788387 scopus 로고    scopus 로고
    • Cytokine transcriptional events during helper T cell subset differentiation
    • Lederer J.A., Perez V.L., DesRoches L., Kim S.M., Abbas A.K., and Lichtman A.H. Cytokine transcriptional events during helper T cell subset differentiation. J Exp Med 184 2 (1996) 397-406
    • (1996) J Exp Med , vol.184 , Issue.2 , pp. 397-406
    • Lederer, J.A.1    Perez, V.L.2    DesRoches, L.3    Kim, S.M.4    Abbas, A.K.5    Lichtman, A.H.6
  • 39
    • 0027400726 scopus 로고
    • Multiple defects of immune cell function in mice with disrupted interferon-gamma genes
    • Dalton D.K., Pitts-Meek S., Keshav S., Figari I.S., Bradley A., and Stewart T.A. Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science 259 5102 (1993) 1739-1742
    • (1993) Science , vol.259 , Issue.5102 , pp. 1739-1742
    • Dalton, D.K.1    Pitts-Meek, S.2    Keshav, S.3    Figari, I.S.4    Bradley, A.5    Stewart, T.A.6
  • 40
    • 0030588570 scopus 로고    scopus 로고
    • The granulomatous response in murine Schistosomiasis mansoni does not switch to Th1 in IL-4-deficient C57BL/6 mice
    • Metwali A., Elliott D., Blum A.M., et al. The granulomatous response in murine Schistosomiasis mansoni does not switch to Th1 in IL-4-deficient C57BL/6 mice. J Immunol 157 10 (1996) 4546-4553
    • (1996) J Immunol , vol.157 , Issue.10 , pp. 4546-4553
    • Metwali, A.1    Elliott, D.2    Blum, A.M.3
  • 41
    • 33747120224 scopus 로고    scopus 로고
    • DeBoy CA, Xin, J., Byram SC, Serpe CJ, Sanders VM, Jones KJ. 2006. Immune-mediated neuroprotection of axotomized mouse facial motoneurons 3 is dependent on the IL-4/STAT6 signaling pathway in CD4+T cells. Exp. Neurol., In Press.
  • 42
    • 0023888290 scopus 로고
    • Delayed astrocyte reaction following facial nerve axotomy
    • Graeber M.B., and Kreutzberg G.W. Delayed astrocyte reaction following facial nerve axotomy. J Neurocytol 17 2 (1988) 209-220
    • (1988) J Neurocytol , vol.17 , Issue.2 , pp. 209-220
    • Graeber, M.B.1    Kreutzberg, G.W.2
  • 43
    • 0024255828 scopus 로고
    • Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells
    • Graeber M.B., Streit W.J., and Kreutzberg G.W. Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells. J Neurosci Res 21 1 (1988) 18-24
    • (1988) J Neurosci Res , vol.21 , Issue.1 , pp. 18-24
    • Graeber, M.B.1    Streit, W.J.2    Kreutzberg, G.W.3
  • 44
    • 0024538004 scopus 로고
    • Peripheral nerve lesion produces increased levels of major histocompatibility complex antigens in the central nervous system
    • Streit W.J., Graeber M.B., and Kreutzberg G.W. Peripheral nerve lesion produces increased levels of major histocompatibility complex antigens in the central nervous system. J Neuroimmunol 21 2-3 (1989) 117-123
    • (1989) J Neuroimmunol , vol.21 , Issue.2-3 , pp. 117-123
    • Streit, W.J.1    Graeber, M.B.2    Kreutzberg, G.W.3
  • 45
    • 0029953016 scopus 로고    scopus 로고
    • Changes in glial fibrillary acidic protein immunoreactivity in the rat facial nucleus following various types of nerve lesions
    • Laskawi R., and Wolff J.R. Changes in glial fibrillary acidic protein immunoreactivity in the rat facial nucleus following various types of nerve lesions. Eur Arch Otorhinolaryngol 253 8 (1996) 475-480
    • (1996) Eur Arch Otorhinolaryngol , vol.253 , Issue.8 , pp. 475-480
    • Laskawi, R.1    Wolff, J.R.2
  • 46
    • 0031815256 scopus 로고    scopus 로고
    • Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis
    • Streit W.J., Semple-Rowland S.L., Hurley S.D., Miller R.C., Popovich P.G., and Stokes B.T. Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis. Exp Neurol 152 1 (1998) 74-87
    • (1998) Exp Neurol , vol.152 , Issue.1 , pp. 74-87
    • Streit, W.J.1    Semple-Rowland, S.L.2    Hurley, S.D.3    Miller, R.C.4    Popovich, P.G.5    Stokes, B.T.6
  • 47
    • 0032900960 scopus 로고    scopus 로고
    • Balancing function vs. self defense: the CNS as an active regulator of immune responses
    • Carson M.J., and Sutcliffe J.G. Balancing function vs. self defense: the CNS as an active regulator of immune responses. J Neurosci Res 55 1 (1999) 1-8
    • (1999) J Neurosci Res , vol.55 , Issue.1 , pp. 1-8
    • Carson, M.J.1    Sutcliffe, J.G.2
  • 49
    • 0036847816 scopus 로고    scopus 로고
    • Microglia as neuroprotective, immunocompetent cells of the CNS
    • Streit W.J. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 40 2 (2002) 133-139
    • (2002) Glia , vol.40 , Issue.2 , pp. 133-139
    • Streit, W.J.1
  • 50
    • 0036847841 scopus 로고    scopus 로고
    • Microglia as liaisons between the immune and central nervous systems: functional implications for multiple sclerosis
    • Carson M.J. Microglia as liaisons between the immune and central nervous systems: functional implications for multiple sclerosis. Glia 40 2 (2002) 218-231
    • (2002) Glia , vol.40 , Issue.2 , pp. 218-231
    • Carson, M.J.1
  • 51
    • 0026738695 scopus 로고
    • Activated microglia mediate neuronal cell injury via a nitric oxide mechanism
    • Chao C.C., Hu S., Molitor T.W., Shaskan E.G., and Peterson P.K. Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J Immunol 149 8 (1992) 2736-2741
    • (1992) J Immunol , vol.149 , Issue.8 , pp. 2736-2741
    • Chao, C.C.1    Hu, S.2    Molitor, T.W.3    Shaskan, E.G.4    Peterson, P.K.5
  • 52
    • 0036934895 scopus 로고    scopus 로고
    • Cytotoxic potential of proinflammatory cytokines: combined deletion of TNF receptors TNFR1 and TNFR2 prevents motoneuron cell death after facial axotomy in adult mouse
    • Raivich G., Liu Z.Q., Kloss C.U., Labow M., Bluethmann H., and Bohatschek M. Cytotoxic potential of proinflammatory cytokines: combined deletion of TNF receptors TNFR1 and TNFR2 prevents motoneuron cell death after facial axotomy in adult mouse. Exp Neurol 178 2 (2002) 186-193
    • (2002) Exp Neurol , vol.178 , Issue.2 , pp. 186-193
    • Raivich, G.1    Liu, Z.Q.2    Kloss, C.U.3    Labow, M.4    Bluethmann, H.5    Bohatschek, M.6
  • 53
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas A.K., Murphy K.M., and Sher A. Functional diversity of helper T lymphocytes. Nature 383 6603 (1996) 787-793
    • (1996) Nature , vol.383 , Issue.6603 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 54
    • 0036605571 scopus 로고    scopus 로고
    • Interleukin-4, interleukin-10, and interleukin-1-receptor antagonist but not transforming growth factor-beta induce ramification and reduce adhesion molecule expression of rat microglial cells
    • Wirjatijasa F., Dehghani F., Blaheta R.A., Korf H.W., and Hailer N.P. Interleukin-4, interleukin-10, and interleukin-1-receptor antagonist but not transforming growth factor-beta induce ramification and reduce adhesion molecule expression of rat microglial cells. J Neurosci Res 68 5 (2002) 579-587
    • (2002) J Neurosci Res , vol.68 , Issue.5 , pp. 579-587
    • Wirjatijasa, F.1    Dehghani, F.2    Blaheta, R.A.3    Korf, H.W.4    Hailer, N.P.5
  • 55
    • 0036594989 scopus 로고    scopus 로고
    • Interleukin-13 and -4 induce death of activated microglia
    • Yang M.S., Park E.J., Sohn S., et al. Interleukin-13 and -4 induce death of activated microglia. Glia 38 4 (2002) 273-280
    • (2002) Glia , vol.38 , Issue.4 , pp. 273-280
    • Yang, M.S.1    Park, E.J.2    Sohn, S.3
  • 56
    • 0030990750 scopus 로고    scopus 로고
    • Prevention of apoptotic motoneuron death in vitro by neurotrophins and muscle extract
    • Kaal E.C., Joosten E.A., and Bar P.R. Prevention of apoptotic motoneuron death in vitro by neurotrophins and muscle extract. Neurochem Int 31 2 (1997) 193-201
    • (1997) Neurochem Int , vol.31 , Issue.2 , pp. 193-201
    • Kaal, E.C.1    Joosten, E.A.2    Bar, P.R.3
  • 57
    • 0035666020 scopus 로고    scopus 로고
    • Ultrastructural localisation of intramuscular expression of BDNF mRNA by silver-gold intensified non-radioactive in situ hybridisation
    • Liem R.S., Brouwer N., and Copray J.C. Ultrastructural localisation of intramuscular expression of BDNF mRNA by silver-gold intensified non-radioactive in situ hybridisation. Histochem Cell Biol 116 6 (2001) 545-551
    • (2001) Histochem Cell Biol , vol.116 , Issue.6 , pp. 545-551
    • Liem, R.S.1    Brouwer, N.2    Copray, J.C.3
  • 58
    • 0027067035 scopus 로고
    • Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
    • Yan Q., Elliott J., and Snider W.D. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature 360 6406 (1992) 753-755
    • (1992) Nature , vol.360 , Issue.6406 , pp. 753-755
    • Yan, Q.1    Elliott, J.2    Snider, W.D.3
  • 59
    • 0027374952 scopus 로고
    • Influences of neurotrophins on mammalian motoneurons in vivo
    • Yan Q., Elliott J.L., Matheson C., et al. Influences of neurotrophins on mammalian motoneurons in vivo. J Neurobiol 24 12 (1993) 1555-1577
    • (1993) J Neurobiol , vol.24 , Issue.12 , pp. 1555-1577
    • Yan, Q.1    Elliott, J.L.2    Matheson, C.3
  • 60
    • 0027131764 scopus 로고
    • Members of several gene families influence survival of rat motoneurons in vitro and in vivo
    • Hughes R.A., Sendtner M., and Thoenen H. Members of several gene families influence survival of rat motoneurons in vitro and in vivo. J Neurosci Res 36 6 (1993) 663-671
    • (1993) J Neurosci Res , vol.36 , Issue.6 , pp. 663-671
    • Hughes, R.A.1    Sendtner, M.2    Thoenen, H.3
  • 61
    • 0030762723 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo
    • Novikov L., Novikova L., and Kellerth J.O. Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo. Neuroscience 79 3 (1997) 765-774
    • (1997) Neuroscience , vol.79 , Issue.3 , pp. 765-774
    • Novikov, L.1    Novikova, L.2    Kellerth, J.O.3
  • 62
    • 0037381513 scopus 로고    scopus 로고
    • Adenoviral gene transfer of GDNF, BDNF and TGF beta 2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motoneurons after facial nerve avulsion
    • Sakamoto T., Kawazoe Y., Shen J.S., et al. Adenoviral gene transfer of GDNF, BDNF and TGF beta 2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motoneurons after facial nerve avulsion. J Neurosci Res 72 1 (2003) 54-64
    • (2003) J Neurosci Res , vol.72 , Issue.1 , pp. 54-64
    • Sakamoto, T.1    Kawazoe, Y.2    Shen, J.S.3
  • 63
    • 0038045085 scopus 로고    scopus 로고
    • alter the expression of neuronal NOS, c-Jun, and p75 and prevent motoneuron death following spinal root avulsion in adult rats
    • Wu W., Li L., Yick L.W., et al. alter the expression of neuronal NOS, c-Jun, and p75 and prevent motoneuron death following spinal root avulsion in adult rats. J Neurotrauma 20 6 (2003) 603-612
    • (2003) J Neurotrauma , vol.20 , Issue.6 , pp. 603-612
    • Wu, W.1    Li, L.2    Yick, L.W.3
  • 64
    • 0033152935 scopus 로고    scopus 로고
    • Cutting edge: clonally restricted production of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3 mRNA by human immune cells and Th1/Th2-polarized expression of their receptors
    • Besser M., and Wank R. Cutting edge: clonally restricted production of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3 mRNA by human immune cells and Th1/Th2-polarized expression of their receptors. J Immunol 162 11 (1999) 6303-6306
    • (1999) J Immunol , vol.162 , Issue.11 , pp. 6303-6306
    • Besser, M.1    Wank, R.2
  • 65
    • 0033103608 scopus 로고    scopus 로고
    • Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?
    • Kerschensteiner M., Gallmeier E., Behrens L., et al. Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?. J Exp Med 189 5 (1999) 865-870
    • (1999) J Exp Med , vol.189 , Issue.5 , pp. 865-870
    • Kerschensteiner, M.1    Gallmeier, E.2    Behrens, L.3
  • 66
    • 0034661765 scopus 로고    scopus 로고
    • Neuroprotection by encephalomyelitis: rescue of mechanically injured neurons and neurotrophin production by CNS-infiltrating T and natural killer cells
    • Hammarberg H., Lidman O., Lundberg C., et al. Neuroprotection by encephalomyelitis: rescue of mechanically injured neurons and neurotrophin production by CNS-infiltrating T and natural killer cells. J Neurosci 20 14 (2000) 5283-5291
    • (2000) J Neurosci , vol.20 , Issue.14 , pp. 5283-5291
    • Hammarberg, H.1    Lidman, O.2    Lundberg, C.3
  • 67
    • 0036226510 scopus 로고    scopus 로고
    • Differential expression of neurotrophic factors and inflammatory cytokines by myelin basic protein-specific and other recruited T cells infiltrating the central nervous system during experimental autoimmune encephalomyelitis
    • Muhallab S., Lundberg C., Gielen A.W., et al. Differential expression of neurotrophic factors and inflammatory cytokines by myelin basic protein-specific and other recruited T cells infiltrating the central nervous system during experimental autoimmune encephalomyelitis. Scand J Immunol 55 3 (2002) 264-273
    • (2002) Scand J Immunol , vol.55 , Issue.3 , pp. 264-273
    • Muhallab, S.1    Lundberg, C.2    Gielen, A.W.3
  • 68
    • 0036845819 scopus 로고    scopus 로고
    • Glatiramer acetate-specific T-helper 1- and 2-type cell lines produce BDNF: implications for multiple sclerosis therapy. Brain-derived neurotrophic factor
    • Ziemssen T., Kumpfel T., Klinkert W.E., Neuhaus O., and Hohlfeld R. Glatiramer acetate-specific T-helper 1- and 2-type cell lines produce BDNF: implications for multiple sclerosis therapy. Brain-derived neurotrophic factor. Brain 152 Pt 11 (2002) 2381-2391
    • (2002) Brain , vol.152 , Issue.PART 11 , pp. 2381-2391
    • Ziemssen, T.1    Kumpfel, T.2    Klinkert, W.E.3    Neuhaus, O.4    Hohlfeld, R.5
  • 69
    • 0041519116 scopus 로고    scopus 로고
    • Functional expression of the TrkC gene, encoding a high affinity receptor for NT-3, in antigen-specific T helper type 2 (Th2) cells
    • Sekimoto M., Tsuji T., Matsuzaki J., et al. Functional expression of the TrkC gene, encoding a high affinity receptor for NT-3, in antigen-specific T helper type 2 (Th2) cells. Immunol Lett 88 3 (2003) 221-226
    • (2003) Immunol Lett , vol.88 , Issue.3 , pp. 221-226
    • Sekimoto, M.1    Tsuji, T.2    Matsuzaki, J.3
  • 70
    • 12344300485 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor supports facial motoneuron survival after facial nerve transection in immunodeficient mice
    • Serpe C.J., Byram S.C., Sanders V.M., and Jones K.J. Brain-derived neurotrophic factor supports facial motoneuron survival after facial nerve transection in immunodeficient mice. Brain Behav Immun 19 2 (2005) 173-180
    • (2005) Brain Behav Immun , vol.19 , Issue.2 , pp. 173-180
    • Serpe, C.J.1    Byram, S.C.2    Sanders, V.M.3    Jones, K.J.4
  • 71
    • 0032146068 scopus 로고    scopus 로고
    • Immune surveillance in the injured nervous system: T-lymphocytes invade the axotomized mouse facial motor nucleus and aggregate around sites of neuronal degeneration
    • Raivich G., Jones L.L., Kloss C.U., Werner A., Neumann H., and Kreutzberg G.W. Immune surveillance in the injured nervous system: T-lymphocytes invade the axotomized mouse facial motor nucleus and aggregate around sites of neuronal degeneration. J Neurosci 18 15 (1998) 5804-5816
    • (1998) J Neurosci , vol.18 , Issue.15 , pp. 5804-5816
    • Raivich, G.1    Jones, L.L.2    Kloss, C.U.3    Werner, A.4    Neumann, H.5    Kreutzberg, G.W.6
  • 73
    • 13144279282 scopus 로고    scopus 로고
    • Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia
    • Harrison J.K., Jiang Y., Chen S., et al. Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. Proc Natl Acad Sci USA 95 18 (1998) 10896-10901
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.18 , pp. 10896-10901
    • Harrison, J.K.1    Jiang, Y.2    Chen, S.3
  • 74
    • 0034652697 scopus 로고    scopus 로고
    • Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation
    • Zujovic V., Benavides J., Vige X., Carter C., and Taupin V. Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation. Glia 29 4 (2000) 305-315
    • (2000) Glia , vol.29 , Issue.4 , pp. 305-315
    • Zujovic, V.1    Benavides, J.2    Vige, X.3    Carter, C.4    Taupin, V.5
  • 76
    • 0033568107 scopus 로고    scopus 로고
    • Axotomy-induced changes in pituitary adenylate cyclase activating polypeptide (PACAP) and PACAP receptor gene expression in the adult rat facial motor nucleus
    • Zhou X., Rodriguez W.I., Casillas R.A., et al. Axotomy-induced changes in pituitary adenylate cyclase activating polypeptide (PACAP) and PACAP receptor gene expression in the adult rat facial motor nucleus. J Neurosci Res 57 6 (1999) 953-961
    • (1999) J Neurosci Res , vol.57 , Issue.6 , pp. 953-961
    • Zhou, X.1    Rodriguez, W.I.2    Casillas, R.A.3
  • 77
    • 0141593401 scopus 로고    scopus 로고
    • Lymphocyte regulation of neuropeptide gene expression after neuronal injury
    • Armstrong B.D., Hu Z., Abad C., et al. Lymphocyte regulation of neuropeptide gene expression after neuronal injury. J Neurosci Res 74 2 (2003) 240-247
    • (2003) J Neurosci Res , vol.74 , Issue.2 , pp. 240-247
    • Armstrong, B.D.1    Hu, Z.2    Abad, C.3
  • 78
    • 0038806327 scopus 로고    scopus 로고
    • PACAP in immunity and inflammation
    • Delgado M., Abad C., Martinez C., et al. PACAP in immunity and inflammation. Ann NY Acad Sci 992 (2003) 141-157
    • (2003) Ann NY Acad Sci , vol.992 , pp. 141-157
    • Delgado, M.1    Abad, C.2    Martinez, C.3
  • 79
    • 4444305508 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide: a potential neuroprotective peptide
    • Somogyvari-Vigh A., and Reglodi D. Pituitary adenylate cyclase activating polypeptide: a potential neuroprotective peptide. Curr Pharm Des 10 23 (2004) 2861-2889
    • (2004) Curr Pharm Des , vol.10 , Issue.23 , pp. 2861-2889
    • Somogyvari-Vigh, A.1    Reglodi, D.2
  • 80
    • 11144245596 scopus 로고    scopus 로고
    • Restoration of axotomy-induced PACAP gene induction in SCID mice with CD4+T-lymphocytes
    • Armstrong B.D., Abad C., Chhith S., et al. Restoration of axotomy-induced PACAP gene induction in SCID mice with CD4+T-lymphocytes. Neuroreport 15 17 (2004) 2647-2650
    • (2004) Neuroreport , vol.15 , Issue.17 , pp. 2647-2650
    • Armstrong, B.D.1    Abad, C.2    Chhith, S.3
  • 81
    • 0034658528 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylyl cyclase-activating polypeptide inhibit tumor necrosis factor-alpha production in injured spinal cord and in activated microglia via a cAMP-dependent pathway
    • Kim W.K., Kan Y., Ganea D., Hart R.P., Gozes I., and Jonakait G.M. Vasoactive intestinal peptide and pituitary adenylyl cyclase-activating polypeptide inhibit tumor necrosis factor-alpha production in injured spinal cord and in activated microglia via a cAMP-dependent pathway. J Neurosci 20 10 (2000) 3622-3630
    • (2000) J Neurosci , vol.20 , Issue.10 , pp. 3622-3630
    • Kim, W.K.1    Kan, Y.2    Ganea, D.3    Hart, R.P.4    Gozes, I.5    Jonakait, G.M.6
  • 82
    • 0036830946 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide promote in vivo generation of memory Th2 cells
    • Delgado M., Leceta J., and Ganea D. Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide promote in vivo generation of memory Th2 cells. Faseb J 16 13 (2002) 1844-1846
    • (2002) Faseb J , vol.16 , Issue.13 , pp. 1844-1846
    • Delgado, M.1    Leceta, J.2    Ganea, D.3
  • 83
    • 0035222230 scopus 로고    scopus 로고
    • Neuropeptides as modulators of macrophage functions. Regulation of cytokine production and antigen presentation by VIP and PACAP
    • Ganea D., and Delgado M. Neuropeptides as modulators of macrophage functions. Regulation of cytokine production and antigen presentation by VIP and PACAP. Arch Immunol Ther Exp (Warsz) 49 2 (2001) 101-110
    • (2001) Arch Immunol Ther Exp (Warsz) , vol.49 , Issue.2 , pp. 101-110
    • Ganea, D.1    Delgado, M.2
  • 84
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • Mantovani A., Sica A., Sozzani S., Allavena P., Vecchi A., and Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25 12 (2004) 677-686
    • (2004) Trends Immunol , vol.25 , Issue.12 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 85
    • 0031063473 scopus 로고    scopus 로고
    • The cellular and molecular basis of peripheral nerve regeneration
    • Fu S.Y., and Gordon T. The cellular and molecular basis of peripheral nerve regeneration. Mol Neurobiol 14 1-2 (1997) 67-116
    • (1997) Mol Neurobiol , vol.14 , Issue.1-2 , pp. 67-116
    • Fu, S.Y.1    Gordon, T.2
  • 86
    • 0027209373 scopus 로고
    • Long-term consequences of impaired regeneration on facial motoneurons in the C57BL/Ola mouse
    • Chen S., and Bisby M.A. Long-term consequences of impaired regeneration on facial motoneurons in the C57BL/Ola mouse. J Comp Neurol 335 4 (1993) 576-585
    • (1993) J Comp Neurol , vol.335 , Issue.4 , pp. 576-585
    • Chen, S.1    Bisby, M.A.2
  • 87
    • 0030987548 scopus 로고    scopus 로고
    • Copolymer 1 induces T cells of the T helper type 2 that crossreact with myelin basic protein and suppress experimental autoimmune encephalomyelitis
    • Aharoni R., Teitelbaum D., Sela M., and Arnon R. Copolymer 1 induces T cells of the T helper type 2 that crossreact with myelin basic protein and suppress experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 94 20 (1997) 10821-10826
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.20 , pp. 10821-10826
    • Aharoni, R.1    Teitelbaum, D.2    Sela, M.3    Arnon, R.4
  • 88
    • 0344198593 scopus 로고    scopus 로고
    • Glatiramer acetate-specific T cells in the brain express T helper 2/3 cytokines and brain-derived neurotrophic factor in situ
    • Aharoni R., Kayhan B., Eilam R., Sela M., and Arnon R. Glatiramer acetate-specific T cells in the brain express T helper 2/3 cytokines and brain-derived neurotrophic factor in situ. Proc Natl Acad Sci USA 100 24 (2003) 14157-14162
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.24 , pp. 14157-14162
    • Aharoni, R.1    Kayhan, B.2    Eilam, R.3    Sela, M.4    Arnon, R.5
  • 89
    • 0344490328 scopus 로고    scopus 로고
    • Therapeutic vaccine for acute and chronic motor neuron diseases: implications for amyotrophic lateral sclerosis
    • Angelov D.N., Waibel S., Guntinas-Lichius O., et al. Therapeutic vaccine for acute and chronic motor neuron diseases: implications for amyotrophic lateral sclerosis. Proc Natl Acad Sci USA 100 8 (2003) 4790-4795
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.8 , pp. 4790-4795
    • Angelov, D.N.1    Waibel, S.2    Guntinas-Lichius, O.3
  • 90
    • 0022443737 scopus 로고
    • Familial adult motor neuron disease: amyotrophic lateral sclerosis
    • Mulder D.W., Kurland L.T., Offord K.P., and Beard C.M. Familial adult motor neuron disease: amyotrophic lateral sclerosis. Neurology 36 4 (1986) 511-517
    • (1986) Neurology , vol.36 , Issue.4 , pp. 511-517
    • Mulder, D.W.1    Kurland, L.T.2    Offord, K.P.3    Beard, C.M.4
  • 91
    • 0035833937 scopus 로고    scopus 로고
    • Immune reactivity in a mouse model of familial ALS correlates with disease progression
    • Alexianu M.E., Kozovska M., and Appel S.H. Immune reactivity in a mouse model of familial ALS correlates with disease progression. Neurology 57 7 (2001) 1282-1289
    • (2001) Neurology , vol.57 , Issue.7 , pp. 1282-1289
    • Alexianu, M.E.1    Kozovska, M.2    Appel, S.H.3
  • 92
    • 0027473452 scopus 로고
    • Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis
    • Engelhardt J.I., Tajti J., and Appel S.H. Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis. Arch Neurol 50 1 (1993) 30-36
    • (1993) Arch Neurol , vol.50 , Issue.1 , pp. 30-36
    • Engelhardt, J.I.1    Tajti, J.2    Appel, S.H.3
  • 93
    • 0024997449 scopus 로고
    • Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis
    • Lampson L.A., Kushner P.D., and Sobel R.A. Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis. Ann Neurol 28 3 (1990) 365-372
    • (1990) Ann Neurol , vol.28 , Issue.3 , pp. 365-372
    • Lampson, L.A.1    Kushner, P.D.2    Sobel, R.A.3
  • 94
    • 0024955336 scopus 로고
    • Lymphocytic infiltration in the spinal cord of patients with amyotrophic lateral sclerosis
    • Troost D., van den Oord J.J., de Jong J.M., and Swaab D.F. Lymphocytic infiltration in the spinal cord of patients with amyotrophic lateral sclerosis. Clin Neuropathol 8 6 (1989) 289-294
    • (1989) Clin Neuropathol , vol.8 , Issue.6 , pp. 289-294
    • Troost, D.1    van den Oord, J.J.2    de Jong, J.M.3    Swaab, D.F.4
  • 95
    • 12344310088 scopus 로고    scopus 로고
    • Inflammation in amyotrophic lateral sclerosis spinal cord and brain is mediated by activated macrophages, mast cells and T cells
    • Graves M.C., Fiala M., Dinglasan L.A., et al. Inflammation in amyotrophic lateral sclerosis spinal cord and brain is mediated by activated macrophages, mast cells and T cells. Amyotroph Lateral Scler Other Motor Neuron Disord 5 4 (2004) 213-219
    • (2004) Amyotroph Lateral Scler Other Motor Neuron Disord , vol.5 , Issue.4 , pp. 213-219
    • Graves, M.C.1    Fiala, M.2    Dinglasan, L.A.3
  • 97
    • 19944432585 scopus 로고    scopus 로고
    • Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis
    • Jiang Y.M., Yamamoto M., Kobayashi Y., et al. Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis. Ann Neurol 57 2 (2005) 236-251
    • (2005) Ann Neurol , vol.57 , Issue.2 , pp. 236-251
    • Jiang, Y.M.1    Yamamoto, M.2    Kobayashi, Y.3
  • 98
    • 3042511616 scopus 로고    scopus 로고
    • Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis
    • Karlsson J., Fong K.S., Hansson M.J., Elmer E., Csiszar K., and Keep M.F. Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis. J Neurosurg 101 1 (2004) 128-137
    • (2004) J Neurosurg , vol.101 , Issue.1 , pp. 128-137
    • Karlsson, J.1    Fong, K.S.2    Hansson, M.J.3    Elmer, E.4    Csiszar, K.5    Keep, M.F.6
  • 99
    • 0027991954 scopus 로고
    • Evidence for autoimmunity in amyotrophic lateral sclerosis
    • Appel S.H., Smith R.G., Engelhardt J.I., and Stefani E. Evidence for autoimmunity in amyotrophic lateral sclerosis. J Neurol Sci 124 (1994) 14-19
    • (1994) J Neurol Sci , vol.124 , pp. 14-19
    • Appel, S.H.1    Smith, R.G.2    Engelhardt, J.I.3    Stefani, E.4
  • 100
    • 0033588966 scopus 로고    scopus 로고
    • Peripheral axotomy slows motoneuron degeneration in a transgenic mouse line expressing mutant SOD1 G93A
    • Kong J., and Xu Z. Peripheral axotomy slows motoneuron degeneration in a transgenic mouse line expressing mutant SOD1 G93A. J Comp Neurol 412 2 (1999) 373-380
    • (1999) J Comp Neurol , vol.412 , Issue.2 , pp. 373-380
    • Kong, J.1    Xu, Z.2


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