-
1
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham R.T. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15:2001;2177-2196.
-
(2001)
Genes Dev.
, vol.15
, pp. 2177-2196
-
-
Abraham, R.T.1
-
2
-
-
0035735472
-
Mrc1 transduces signals of DNA replication stress to activate Rad53
-
Alcasabas A.A., Osborn A.J., Bachant J., Hu F., Werler P.J., Bousset K., Furuya K., Diffley J.F., Carr A.M., Elledge S.J. Mrc1 transduces signals of DNA replication stress to activate Rad53. Nat. Cell Biol. 3:2001;958-965.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 958-965
-
-
Alcasabas, A.A.1
Osborn, A.J.2
Bachant, J.3
Hu, F.4
Werler, P.J.5
Bousset, K.6
Furuya, K.7
Diffley, J.F.8
Carr, A.M.9
Elledge, S.J.10
-
3
-
-
0035927713
-
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses
-
Bao S., Tibbetts R.S., Brumbaugh K.M., Fang Y., Richardson D.A., Ali A., Chen S.M., Abraham R.T., Wang X.F. ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses. Nature. 411:2001;969-974.
-
(2001)
Nature
, vol.411
, pp. 969-974
-
-
Bao, S.1
Tibbetts, R.S.2
Brumbaugh, K.M.3
Fang, Y.4
Richardson, D.A.5
Ali, A.6
Chen, S.M.7
Abraham, R.T.8
Wang, X.F.9
-
5
-
-
0035997368
-
DNA replication in eukaryotic cells
-
Bell S.P., Dutta A. DNA replication in eukaryotic cells. Annu. Rev. Biochem. 71:2002;333-374.
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 333-374
-
-
Bell, S.P.1
Dutta, A.2
-
6
-
-
0033956543
-
Characterization of Schizosaccharomyces pombe Hus1: A PCNA-related protein that associates with Rad1 and Rad9
-
Caspari T., Dahlen M., Kanter-Smoler G., Lindsay H.D., Hofmann K., Papadimitriou K., Sunnerhagen P., Carr A.M. Characterization of Schizosaccharomyces pombe Hus1. a PCNA-related protein that associates with Rad1 and Rad9 Mol. Cell. Biol. 20:2000;1254-1262.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1254-1262
-
-
Caspari, T.1
Dahlen, M.2
Kanter-Smoler, G.3
Lindsay, H.D.4
Hofmann, K.5
Papadimitriou, K.6
Sunnerhagen, P.7
Carr, A.M.8
-
7
-
-
0028899480
-
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
-
Chen J., Jackson P.K., Kirschner M.W., Dutta A. Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature. 374:1995;386-388.
-
(1995)
Nature
, vol.374
, pp. 386-388
-
-
Chen, J.1
Jackson, P.K.2
Kirschner, M.W.3
Dutta, A.4
-
8
-
-
0030271388
-
The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts
-
Coleman T.R., Carpenter P.B., Dunphy W.G. The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts. Cell. 87:1996;53-63.
-
(1996)
Cell
, vol.87
, pp. 53-63
-
-
Coleman, T.R.1
Carpenter, P.B.2
Dunphy, W.G.3
-
9
-
-
0028844502
-
Fission yeast rad17: A homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins
-
Griffiths D.J., Barbet N.C., McCready S., Lehmann A.R., Carr A.M. Fission yeast rad17. a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins EMBO J. 14:1995;5812-5823.
-
(1995)
EMBO J.
, vol.14
, pp. 5812-5823
-
-
Griffiths, D.J.1
Barbet, N.C.2
McCready, S.3
Lehmann, A.R.4
Carr, A.M.5
-
10
-
-
0343294336
-
Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends
-
Guo Z., Dunphy W.G. Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends. Mol. Biol. Cell. 11:2000;1535-1546.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 1535-1546
-
-
Guo, Z.1
Dunphy, W.G.2
-
11
-
-
0034312277
-
Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts
-
Guo Z., Kumagai A., Wang S.X., Dunphy W.G. Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts. Genes Dev. 14:2000;2745-2756.
-
(2000)
Genes Dev.
, vol.14
, pp. 2745-2756
-
-
Guo, Z.1
Kumagai, A.2
Wang, S.X.3
Dunphy, W.G.4
-
12
-
-
0034649590
-
Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint
-
Hekmat-Nejad M., You Z., Yee M., Newport J.W., Cimprich K.A. Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint. Curr. Biol. 10:2000;1565-1573.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1565-1573
-
-
Hekmat-Nejad, M.1
You, Z.2
Yee, M.3
Newport, J.W.4
Cimprich, K.A.5
-
13
-
-
0028245269
-
Recombinant replication protein A: Expression, complex formation, and functional characterization
-
Henricksen L.A., Umbricht C.B., Wold M.S. Recombinant replication protein A. expression, complex formation, and functional characterization J. Biol. Chem. 269:1994;11121-11132.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 11121-11132
-
-
Henricksen, L.A.1
Umbricht, C.B.2
Wold, M.S.3
-
15
-
-
0034659412
-
Xenopus Cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading
-
Jares P., Blow J.J. Xenopus Cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading. Genes Dev. 14:2000;1528-1540.
-
(2000)
Genes Dev.
, vol.14
, pp. 1528-1540
-
-
Jares, P.1
Blow, J.J.2
-
16
-
-
0035955398
-
Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms
-
Kondo T., Wakayama T., Naiki T., Matsumoto K., Sugimoto K. Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms. Science. 294:2001;867-870.
-
(2001)
Science
, vol.294
, pp. 867-870
-
-
Kondo, T.1
Wakayama, T.2
Naiki, T.3
Matsumoto, K.4
Sugimoto, K.5
-
17
-
-
0033634679
-
Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts
-
Kumagai A., Dunphy W.G. Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts. Mol. Cell. 6:2000;839-849.
-
(2000)
Mol. Cell
, vol.6
, pp. 839-849
-
-
Kumagai, A.1
Dunphy, W.G.2
-
18
-
-
0032555924
-
The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts
-
Kumagai A., Guo Z., Emami K.H., Wang S.X., Dunphy W.G. The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts. J. Cell Biol. 142:1998;1559-1569.
-
(1998)
J. Cell Biol.
, vol.142
, pp. 1559-1569
-
-
Kumagai, A.1
Guo, Z.2
Emami, K.H.3
Wang, S.X.4
Dunphy, W.G.5
-
19
-
-
0035158899
-
Positive regulation of Wee1 by Chk1 and 14-3-3 proteins
-
Lee J., Kumagai A., Dunphy W.G. Positive regulation of Wee1 by Chk1 and 14-3-3 proteins. Mol. Biol. Cell. 12:2001;551-563.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 551-563
-
-
Lee, J.1
Kumagai, A.2
Dunphy, W.G.3
-
20
-
-
17644432403
-
Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint
-
Liu Q., Guntuku S., Cui X.S., Matsuoka S., Cortez D., Tamai K., Luo G., Carattini-Rivera S., DeMayo F., Bradley A.et al. Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes Dev. 14:2000;1448-1459.
-
(2000)
Genes Dev.
, vol.14
, pp. 1448-1459
-
-
Liu, Q.1
Guntuku, S.2
Cui, X.S.3
Matsuoka, S.4
Cortez, D.5
Tamai, K.6
Luo, G.7
Carattini-Rivera, S.8
DeMayo, F.9
Bradley, A.10
-
21
-
-
0032511148
-
Geminin, an inhibitor of DNA replication, is degraded during mitosis
-
McGarry T.J., Kirschner M.W. Geminin, an inhibitor of DNA replication, is degraded during mitosis. Cell. 93:1998;1043-1053.
-
(1998)
Cell
, vol.93
, pp. 1043-1053
-
-
McGarry, T.J.1
Kirschner, M.W.2
-
22
-
-
0036531901
-
A unified view of the DNA-damage checkpoint
-
Melo J., Toczyski D. A unified view of the DNA-damage checkpoint. Curr. Opin. Cell Biol. 14:2002;237-245.
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 237-245
-
-
Melo, J.1
Toczyski, D.2
-
23
-
-
0035498938
-
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
-
Melo J.A., Cohen J., Toczyski D.P. Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev. 15:2001;2809-2821.
-
(2001)
Genes Dev.
, vol.15
, pp. 2809-2821
-
-
Melo, J.A.1
Cohen, J.2
Toczyski, D.P.3
-
24
-
-
0034703330
-
Activation of the DNA replication checkpoint through RNA synthesis by primase
-
Michael W.M., Ott R., Fanning E., Newport J. Activation of the DNA replication checkpoint through RNA synthesis by primase. Science. 289:2000;2133-2137.
-
(2000)
Science
, vol.289
, pp. 2133-2137
-
-
Michael, W.M.1
Ott, R.2
Fanning, E.3
Newport, J.4
-
25
-
-
0032190507
-
Xenopus Cdc45-dependent loading of DNA polymerase α onto chromatin under the control of S-phase Cdk
-
Mimura S., Takisawa H. Xenopus Cdc45-dependent loading of DNA polymerase α onto chromatin under the control of S-phase Cdk. EMBO J. 17:1998;5699-5707.
-
(1998)
EMBO J.
, vol.17
, pp. 5699-5707
-
-
Mimura, S.1
Takisawa, H.2
-
26
-
-
0033936230
-
Central role for Cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts
-
Mimura S., Masuda T., Matsui T., Takisawa H. Central role for Cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts. Genes Cells. 5:2000;439-452.
-
(2000)
Genes Cells
, vol.5
, pp. 439-452
-
-
Mimura, S.1
Masuda, T.2
Matsui, T.3
Takisawa, H.4
-
28
-
-
0034723198
-
Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity
-
Prokhorova T.A., Blow J.J. Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity. J. Biol. Chem. 275:2000;2491-2498.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2491-2498
-
-
Prokhorova, T.A.1
Blow, J.J.2
-
29
-
-
0035736486
-
Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1
-
Tanaka K., Russell P. Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1. Nat. Cell Biol. 3:2001;966-972.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 966-972
-
-
Tanaka, K.1
Russell, P.2
-
30
-
-
0029900699
-
In vitro reconstitution of human replication factor C from its five subunits
-
Uhlmann F., Cai J., Flores-Rozas H., Dean F.B., Finkelstein J., O'Donnell M., Hurwitz J. In vitro reconstitution of human replication factor C from its five subunits. Proc. Natl. Acad. Sci. USA. 93:1996;6521-6526.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6521-6526
-
-
Uhlmann, F.1
Cai, J.2
Flores-Rozas, H.3
Dean, F.B.4
Finkelstein, J.5
O'Donnell, M.6
Hurwitz, J.7
-
31
-
-
0034235463
-
Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes
-
Venclovas C., Thelen M.P. Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes. Nucleic Acids Res. 28:2000;2481-2493.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2481-2493
-
-
Venclovas, C.1
Thelen, M.P.2
-
32
-
-
0035942103
-
DNA polymerase ε is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts
-
Waga S., Masuda T., Takisawa H., Sugino A. DNA polymerase ε is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts. Proc. Natl. Acad. Sci. USA. 98:2001;4978-4983.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4978-4983
-
-
Waga, S.1
Masuda, T.2
Takisawa, H.3
Sugino, A.4
-
33
-
-
0034671935
-
Evidence for sequential action of Cdc7 and Cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts
-
Walter J.C. Evidence for sequential action of Cdc7 and Cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts. J. Biol. Chem. 275:2000;39773-39778.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39773-39778
-
-
Walter, J.C.1
-
34
-
-
0033637837
-
Initiation of eukaryotic DNA replication: Origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase α
-
Walter J., Newport J. Initiation of eukaryotic DNA replication. origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase α Mol. Cell. 5:2000;617-627.
-
(2000)
Mol. Cell
, vol.5
, pp. 617-627
-
-
Walter, J.1
Newport, J.2
-
35
-
-
0030908093
-
Replication protein A: A heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism
-
Wold M.S. Replication protein A. a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism Annu. Rev. Biochem. 66:1997;61-92.
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 61-92
-
-
Wold, M.S.1
-
36
-
-
0037178814
-
The role of single-stranded DNA and polymerase α in establishing the ATR, Hus1 DNA replication checkpoint
-
You Z., Kong L., Newport J. The role of single-stranded DNA and polymerase α in establishing the ATR, Hus1 DNA replication checkpoint. J. Biol. Chem. 277:2002;27088-27093.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27088-27093
-
-
You, Z.1
Kong, L.2
Newport, J.3
-
37
-
-
0034967556
-
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
-
Zhao H., Piwnica-Worms H. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol. Cell. Biol. 21:2001;4129-4139.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
38
-
-
0032562610
-
Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin
-
Zou L., Stillman B. Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Science. 280:1998;593-596.
-
(1998)
Science
, vol.280
, pp. 593-596
-
-
Zou, L.1
Stillman, B.2
-
39
-
-
0037080675
-
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
-
Zou L., Cortez D., Elledge S.J. Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin. Genes Dev. 16:2002;198-208.
-
(2002)
Genes Dev.
, vol.16
, pp. 198-208
-
-
Zou, L.1
Cortez, D.2
Elledge, S.J.3
|