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Volumn 9, Issue 4, 2006, Pages 423-435

Catabolic effects of gastric bypass in a diet-induced obese rat model

Author keywords

Body weight; Cytokines; Gastrointestinal hormones; Neuropeptides; Roux en Y gastric bypass

Indexed keywords

ADIPOCYTOKINE; ALPHA INTERMEDIN; ANOREXIGENIC AGENT; CHOLECYSTOKININ; CORTICOSTERONE; CYTOKINE; GASTROINTESTINAL HORMONE; GHRELIN; GLUCOCORTICOID; INSULIN; INTERLEUKIN 6; LEPTIN; NEUROPEPTIDE; NEUROTRANSMITTER; OREXIN; PEPTIDE YY; RESISTIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 33746189656     PISSN: 13631950     EISSN: 15353885     Source Type: Journal    
DOI: 10.1097/01.mco.0000232903.04910.7b     Document Type: Review
Times cited : (23)

References (131)
  • 1
    • 5044242948 scopus 로고    scopus 로고
    • Bariatric surgery: A systematic review and meta-analysis
    • Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA 2004; 292:1724-1737.
    • (2004) JAMA , vol.292 , pp. 1724-1737
    • Buchwald, H.1    Avidor, Y.2    Braunwald, E.3
  • 2
    • 3042758709 scopus 로고    scopus 로고
    • A surgical rat model of human Roux-en-Y gastric bypass
    • Meguid MM, Ramos EJ, Suzuki S, et al. A surgical rat model of human Roux-en-Y gastric bypass. J Gastrointest Surg 2004; 8:621-630.
    • (2004) J Gastrointest Surg , vol.8 , pp. 621-630
    • Meguid, M.M.1    Ramos, E.J.2    Suzuki, S.3
  • 3
    • 0347123635 scopus 로고    scopus 로고
    • Application of genomic technologies: DNA microarrays and metabolic profiling of obesity in the hypothalamus and in subcutaneous fat
    • Middleton FA, Ramos EJ, Xu Y, et al. Application of genomic technologies: DNA microarrays and metabolic profiling of obesity in the hypothalamus and in subcutaneous fat. Nutrition 2004; 20:14-25.
    • (2004) Nutrition , vol.20 , pp. 14-25
    • Middleton, F.A.1    Ramos, E.J.2    Xu, Y.3
  • 4
    • 0042328038 scopus 로고    scopus 로고
    • Is obesity an inflammatory disease?
    • Ramos EJ, Xu Y, Romanova I, et al. Is obesity an inflammatory disease? Surgery 2003; 134:329-335.
    • (2003) Surgery , vol.134 , pp. 329-335
    • Ramos, E.J.1    Xu, Y.2    Romanova, I.3
  • 5
    • 9144254217 scopus 로고    scopus 로고
    • Neurobiologic changes in the hypothalamus associated with weight loss after gastric bypass
    • Romanova IV, Ramos EJ, Xu Y, et al. Neurobiologic changes in the hypothalamus associated with weight loss after gastric bypass. J Am Coll Surg 2004; 199:887-895.
    • (2004) J Am Coll Surg , vol.199 , pp. 887-895
    • Romanova, I.V.1    Ramos, E.J.2    Xu, Y.3
  • 6
    • 24344498306 scopus 로고    scopus 로고
    • Changes in GI hormones and their effect on gastric emptying and transit times after Roux-en-Y gastric bypass in rat model
    • Suzuki S, Ramos EJ, Goncalves CG, et al. Changes in GI hormones and their effect on gastric emptying and transit times after Roux-en-Y gastric bypass in rat model. Surgery 2005; 138:283-290. Very important study that shows the altered profile of food intake regulating hormones after RYGB. The results contribute to the understanding of mechanisms leading to weight loss.
    • (2005) Surgery , vol.138 , pp. 283-290
    • Suzuki, S.1    Ramos, E.J.2    Goncalves, C.G.3
  • 7
    • 3843118960 scopus 로고    scopus 로고
    • Gene expression profiles post Roux-en-Y gastric bypass
    • Xu Y, Ramos EJ, Middleton F, et al. Gene expression profiles post Roux-en-Y gastric bypass. Surgery 2004; 136:246-252.
    • (2004) Surgery , vol.136 , pp. 246-252
    • Xu, Y.1    Ramos, E.J.2    Middleton, F.3
  • 8
    • 33746230782 scopus 로고    scopus 로고
    • Hypothalamic integration of immune function and metabolism
    • Kalsbeek A, Fliers E, Hofman MA, et al., editors. Amsterdam: Elsevier
    • Guijarro A, Laviano A, Meguid MM. Hypothalamic integration of immune function and metabolism. In: Kalsbeek A, Fliers E, Hofman MA, et al., editors. Hypothalamic integration of energy metabolism, progress in brain research. Amsterdam: Elsevier; 2006. pp. 212-228. This review illustrates how the immune and neuroendocrine systems cross talk to regulate metabolism at peripheral and central levels in both physiological and pathological states, including infectious process, cachexia and obesity.
    • (2006) Hypothalamic Integration of Energy Metabolism, Progress in Brain Research , pp. 212-228
    • Guijarro, A.1    Laviano, A.2    Meguid, M.M.3
  • 9
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature 2001; 414:782-787.
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3
  • 10
    • 12344266697 scopus 로고    scopus 로고
    • How obesity causes diabetes: Not a tall tale
    • Lazar MA. How obesity causes diabetes: not a tall tale. Science 2005; 307:373-375. In this short viewpoint the parallel evolution of obesity and type 2 diabetes mellitus is described, as well as the close relationship between the pathogenesis of these diseases.
    • (2005) Science , vol.307 , pp. 373-375
    • Lazar, M.A.1
  • 11
    • 0037065354 scopus 로고    scopus 로고
    • Bariatric surgery and long-term control of morbid obesity
    • Brolin RE. Bariatric surgery and long-term control of morbid obesity. JAMA 2002; 288:2793-2796.
    • (2002) JAMA , vol.288 , pp. 2793-2796
    • Brolin, R.E.1
  • 12
    • 0037048669 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults, 1999-2000
    • Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 2002; 288:1723-1727.
    • (2002) JAMA , vol.288 , pp. 1723-1727
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3    Johnson, C.L.4
  • 13
    • 0036936442 scopus 로고    scopus 로고
    • The extent of the problem of obesity
    • O'Brien PE, Dixon JB. The extent of the problem of obesity. Am J Surg 2002; 184:4S-8S.
    • (2002) Am J Surg , vol.184
    • O'Brien, P.E.1    Dixon, J.B.2
  • 14
    • 0003447646 scopus 로고
    • US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, Hyattsville, Maryland
    • National Health and Nutrition Examination Survey [NHANES] III. US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics, Hyattsville, Maryland; 1994.
    • (1994) National Health and Nutrition Examination Survey [NHANES] III
  • 15
    • 0037423144 scopus 로고    scopus 로고
    • Obesity and the environment: Where do we go from here?
    • Hill JO, Wyatt HR, Reed GW, Peters JC. Obesity and the environment: where do we go from here? Science 2003; 299:853-855.
    • (2003) Science , vol.299 , pp. 853-855
    • Hill, J.O.1    Wyatt, H.R.2    Reed, G.W.3    Peters, J.C.4
  • 17
    • 2942689978 scopus 로고    scopus 로고
    • Gastric bypass for obesity: Mechanisms of weight loss and diabetes resolution
    • Cummings DE, Overduin J, Foster-Schubert KE. Gastric bypass for obesity: mechanisms of weight loss and diabetes resolution. J Clin Endocrinol Metab 2004; 89:2608-2615.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2608-2615
    • Cummings, D.E.1    Overduin, J.2    Foster-Schubert, K.E.3
  • 18
    • 29144524774 scopus 로고    scopus 로고
    • Accelerated growth of bariatric surgery with the introduction of minimally invasive surgery: Invited critique
    • Meguid MMMP, Munshi IAM. Accelerated growth of bariatric surgery with the introduction of minimally invasive surgery: invited critique. Arch Surg 2005; 140:1203.
    • (2005) Arch Surg , vol.140 , pp. 1203
    • Meguid, M.M.M.P.1    Munshi, I.A.M.2
  • 19
    • 26844494491 scopus 로고    scopus 로고
    • Trends in bariatric surgical procedures
    • Santry HP, Gillen DL, Lauderdale DS. Trends in bariatric surgical procedures. JAMA 2005; 294:1909-1917. This study evaluates the nationwide (USA) trend in weight loss surgery, providing detailed patient characteristics including gender differences and financial state insurance quality. Further, it gives information about the clinical outcome after the surgical procedures.
    • (2005) JAMA , vol.294 , pp. 1909-1917
    • Santry, H.P.1    Gillen, D.L.2    Lauderdale, D.S.3
  • 20
    • 10844295087 scopus 로고    scopus 로고
    • Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery
    • Sjostrom L, Lindroos AK, Peltonen M, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med 2004; 351:2683-2693.
    • (2004) N Engl J Med , vol.351 , pp. 2683-2693
    • Sjostrom, L.1    Lindroos, A.K.2    Peltonen, M.3
  • 21
    • 0037162116 scopus 로고    scopus 로고
    • Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery
    • Cummings DE, Weigle DS, Frayo RS, et al. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med 2002; 346:1623-1630.
    • (2002) N Engl J Med , vol.346 , pp. 1623-1630
    • Cummings, D.E.1    Weigle, D.S.2    Frayo, R.S.3
  • 22
    • 2942647329 scopus 로고    scopus 로고
    • Changes of body weight and plasma ghrelin levels after gastric banding and gastric bypass
    • Stoeckli R, Chanda R, Langer I, Keller U. Changes of body weight and plasma ghrelin levels after gastric banding and gastric bypass. Obes Res 2004; 12:346-350.
    • (2004) Obes Res , vol.12 , pp. 346-350
    • Stoeckli, R.1    Chanda, R.2    Langer, I.3    Keller, U.4
  • 23
    • 0036403294 scopus 로고    scopus 로고
    • Gastric bypass model in the obese rat to study metabolic mechanisms of weight loss
    • Xu Y, Ohinata K, Meguid MM, et al. Gastric bypass model in the obese rat to study metabolic mechanisms of weight loss. J Surg Res 2002; 107:56-63.
    • (2002) J Surg Res , vol.107 , pp. 56-63
    • Xu, Y.1    Ohinata, K.2    Meguid, M.M.3
  • 24
    • 0028036452 scopus 로고
    • Weight loss and dietary intake after vertical banded gastroplasty and Roux-en-Y gastric bypass
    • Brolin RL, Robertson LB, Kenler HA, Cody RP. Weight loss and dietary intake after vertical banded gastroplasty and Roux-en-Y gastric bypass. Ann Surg 1994; 220:782-790.
    • (1994) Ann Surg , vol.220 , pp. 782-790
    • Brolin, R.L.1    Robertson, L.B.2    Kenler, H.A.3    Cody, R.P.4
  • 25
    • 1542378699 scopus 로고    scopus 로고
    • Hormonal changes after Roux-en Y gastric bypass for morbid obesity and the control of type-II diabetes mellitus
    • Clements RH, Gonzalez QH, Long CI, et al. Hormonal changes after Roux-en Y gastric bypass for morbid obesity and the control of type-II diabetes mellitus. Am Surg 2004; 70:1-4.
    • (2004) Am Surg , vol.70 , pp. 1-4
    • Clements, R.H.1    Gonzalez, Q.H.2    Long, C.I.3
  • 26
    • 0346057842 scopus 로고    scopus 로고
    • Fundus functionality and ghrelin concentrations after bariatric surgery
    • Fruhbeck G, Diez CA, Gil MJ. Fundus functionality and ghrelin concentrations after bariatric surgery. N Engl J Med 2004; 350:308-309.
    • (2004) N Engl J Med , vol.350 , pp. 308-309
    • Fruhbeck, G.1    Diez, C.A.2    Gil, M.J.3
  • 27
    • 23644445925 scopus 로고    scopus 로고
    • Effect of bariatric surgery on adipose tissue regulatory peptides and growth hormone secretion
    • Holdstock C, Engstrom BE, Ohrvall M, et al. Effect of bariatric surgery on adipose tissue regulatory peptides and growth hormone secretion. Asia Pac J Clin Nutr 2004; 13:S41.
    • (2004) Asia Pac J Clin Nutr , vol.13
    • Holdstock, C.1    Engstrom, B.E.2    Ohrvall, M.3
  • 28
    • 12244288887 scopus 로고    scopus 로고
    • Effects of Roux-en-Y gastric bypass surgery on fasting and postprandial concentrations of plasma ghrelin, peptide YY, and insulin
    • Korner J, Bessler M, Cirilo LJ, et al. Effects of Roux-en-Y gastric bypass surgery on fasting and postprandial concentrations of plasma ghrelin, peptide YY, and insulin. J Clin Endocrinol Metab 2005; 90:359-365. One of the first studies which investigated changes in PYY after RYGB in humans. The findings contribute to the understanding of neuroendocrine changes after RYGB.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 359-365
    • Korner, J.1    Bessler, M.2    Cirilo, L.J.3
  • 29
    • 4644222495 scopus 로고    scopus 로고
    • Calorie intake and meal patterns up to 4 years after Roux-en-Y gastric bypass surgery
    • Warde-Kamar J, Rogers M, Flancbaum L, Laferrere B. Calorie intake and meal patterns up to 4 years after Roux-en-Y gastric bypass surgery. Obes Surg 2004; 14:1070-1079.
    • (2004) Obes Surg , vol.14 , pp. 1070-1079
    • Warde-Kamar, J.1    Rogers, M.2    Flancbaum, L.3    Laferrere, B.4
  • 30
    • 30144444692 scopus 로고    scopus 로고
    • Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters
    • Le Roux CW, Aylwin SJ, Batterham RL, et al. Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters. Ann Surg 2006; 243:108-114. In this paper the authors study the meal-stimulated response of gut hormones in patients following RGYB or gastric bypass, allowing a comparison between the mechanisms that operate in each surgery procedure to achieve weight loss. In addition, they study the role of PYY in weight loss reduction in a rat model of jejunointestinal bypass.
    • (2006) Ann Surg , vol.243 , pp. 108-114
    • Le Roux, C.W.1    Aylwin, S.J.2    Batterham, R.L.3
  • 31
    • 27644558643 scopus 로고    scopus 로고
    • Changes in C-reactive protein predict insulin sensitivity in severely obese individuals after weight loss surgery
    • Gletsu N, Lin E, Khaitan L, et al. Changes in C-reactive protein predict insulin sensitivity in severely obese individuals after weight loss surgery. J Gastrointest Surg 2005; 9:1119-1126.
    • (2005) J Gastrointest Surg , vol.9 , pp. 1119-1126
    • Gletsu, N.1    Lin, E.2    Khaitan, L.3
  • 32
    • 30544443731 scopus 로고    scopus 로고
    • CRP reduction following gastric bypass surgery is most pronounced in insulin-sensitive subjects
    • Lond
    • Holdstock C, Lind L, Engstrom BE, et al. CRP reduction following gastric bypass surgery is most pronounced in insulin-sensitive subjects. Int J Obes (Lond) 2005; 29:1275-1280.
    • (2005) Int J Obes , vol.29 , pp. 1275-1280
    • Holdstock, C.1    Lind, L.2    Engstrom, B.E.3
  • 33
    • 11444261322 scopus 로고    scopus 로고
    • Differential effect of weight loss on insulin resistance in surgically treated obese patients
    • Muscelli E, Mingrone G, Camastra S, et al. Differential effect of weight loss on insulin resistance in surgically treated obese patients. Am J Med 2005; 118:51-57.
    • (2005) Am J Med , vol.118 , pp. 51-57
    • Muscelli, E.1    Mingrone, G.2    Camastra, S.3
  • 34
    • 2642527242 scopus 로고    scopus 로고
    • The decrease in plasma ghrelin concentrations following bariatric surgery depends on the functional integrity of the fundus
    • Fruhbeck G, Diez-Caballero A, Gil MJ, et al. The decrease in plasma ghrelin concentrations following bariatric surgery depends on the functional integrity of the fundus. Obes Surg 2004; 14:606-612.
    • (2004) Obes Surg , vol.14 , pp. 606-612
    • Fruhbeck, G.1    Diez-Caballero, A.2    Gil, M.J.3
  • 35
    • 2942558193 scopus 로고    scopus 로고
    • Plasma ghrelin levels and hunger scores in humans initiating meals voluntarily without time- and food-related cues
    • Cummings DE, Frayo RS, Marmonier C, et al. Plasma ghrelin levels and hunger scores in humans initiating meals voluntarily without time- and food-related cues. Am J Physiol Endocrinol Metab 2004; 287:E297-E304.
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Cummings, D.E.1    Frayo, R.S.2    Marmonier, C.3
  • 36
    • 6344238893 scopus 로고    scopus 로고
    • Short-term effects of gastric bypass surgery on circulating ghrelin levels
    • Morinigo R, Casamitjana R, Moize V, et al. Short-term effects of gastric bypass surgery on circulating ghrelin levels. Obes Res 2004; 12:1108-1116.
    • (2004) Obes Res , vol.12 , pp. 1108-1116
    • Morinigo, R.1    Casamitjana, R.2    Moize, V.3
  • 37
    • 7644229156 scopus 로고    scopus 로고
    • Morbid obesity and gastric bypass surgery: Biochemical profile
    • Silvestre V, Ruano M, Dominguez Y, et al. Morbid obesity and gastric bypass surgery: biochemical profile. Obes Surg 2004; 14:1227-1232.
    • (2004) Obes Surg , vol.14 , pp. 1227-1232
    • Silvestre, V.1    Ruano, M.2    Dominguez, Y.3
  • 38
    • 4644226667 scopus 로고    scopus 로고
    • Resistin, adiponectin, ghrelin, leptin, and proinflammatory cytokines: Relationships in obesity
    • Vendrell J, Broch M, Vilarrasa N, et al. Resistin, adiponectin, ghrelin, leptin, and proinflammatory cytokines: relationships in obesity. Obes Res 2004; 12:962-971.
    • (2004) Obes Res , vol.12 , pp. 962-971
    • Vendrell, J.1    Broch, M.2    Vilarrasa, N.3
  • 39
    • 0043128858 scopus 로고    scopus 로고
    • Insulin resistance, leptin and TNF-alpha system in morbidly obese women after gastric bypass
    • Molina A, Vendrell J, Gutierrez C, et al. Insulin resistance, leptin and TNF-alpha system in morbidly obese women after gastric bypass. Obes Surg 2003; 13:615-621.
    • (2003) Obes Surg , vol.13 , pp. 615-621
    • Molina, A.1    Vendrell, J.2    Gutierrez, C.3
  • 40
    • 33644634243 scopus 로고    scopus 로고
    • Effects of the biliopancreatic diversion on energy balance in the rat
    • Lond
    • Nadreau E, Baraboi ED, Samson P, et al. Effects of the biliopancreatic diversion on energy balance in the rat. Int J Obes (Lond) 2006; 30:419-429. A timely paper investigating a variety of metabolic changes after biliopancreatic diversion in rats. Because Nadreau et al. measured energy intake and energy expenditure, this study helps us to understand the mechanisms of weight loss after weight loss surgery.
    • (2006) Int J Obes , vol.30 , pp. 419-429
    • Nadreau, E.1    Baraboi, E.D.2    Samson, P.3
  • 41
    • 19544370569 scopus 로고    scopus 로고
    • Comparing rat's to human's age: How old is my rat in people years?
    • Quinn R. Comparing rat's to human's age: how old is my rat in people years? Nutrition 2005; 21:775-777. An essential paper which should be recognized by every researcher who studies rat models. This paper provides insights as to a recurrent question of 'how old is my rat'?
    • (2005) Nutrition , vol.21 , pp. 775-777
    • Quinn, R.1
  • 42
    • 0033082426 scopus 로고    scopus 로고
    • Feeding and body-weight regulation by hypothalamic neuropeptides: Mediation of the actions of leptin
    • Inui A. Feeding and body-weight regulation by hypothalamic neuropeptides: mediation of the actions of leptin. Trends Neurosci 1999; 22:62-67.
    • (1999) Trends Neurosci , vol.22 , pp. 62-67
    • Inui, A.1
  • 43
    • 0034611732 scopus 로고    scopus 로고
    • Central nervous system control of food intake
    • Schwartz MW, Woods SC, Porte D Jr, et al. Central nervous system control of food intake. Nature 2000; 404:661-671.
    • (2000) Nature , vol.404 , pp. 661-671
    • Schwartz, M.W.1    Woods, S.C.2    Porte Jr., D.3
  • 44
    • 33644826507 scopus 로고    scopus 로고
    • The regulation of appetite
    • Druce M, Bloom SR. The regulation of appetite. Arch Dis Child 2006; 91:183-187.
    • (2006) Arch Dis Child , vol.91 , pp. 183-187
    • Druce, M.1    Bloom, S.R.2
  • 45
    • 0014954713 scopus 로고
    • Starvation in man
    • Cahill GF Jr. Starvation in man. N Engl J Med 1970; 282:668-675.
    • (1970) N Engl J Med , vol.282 , pp. 668-675
    • Cahill Jr., G.F.1
  • 46
    • 0027460118 scopus 로고
    • Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting
    • Wing SS, Goldberg AL. Glucocorticoids activate the ATP-ubiquitin- dependent proteolytic system in skeletal muscle during fasting. Am J Physiol Endocrinol Metab 1993; 264:E668-E676.
    • (1993) Am J Physiol Endocrinol Metab , vol.264
    • Wing, S.S.1    Goldberg, A.L.2
  • 47
    • 0028959193 scopus 로고
    • Changes in energy expenditure resulting from altered body weight
    • Leibel RL, Rosenbaum M, Hirsch J. Changes in energy expenditure resulting from altered body weight. N Engl J Med 1995; 332:621-628.
    • (1995) N Engl J Med , vol.332 , pp. 621-628
    • Leibel, R.L.1    Rosenbaum, M.2    Hirsch, J.3
  • 48
    • 0030722214 scopus 로고    scopus 로고
    • Changes in measured resting energy expenditure after Roux-en-Y gastric bypass for clinically severe obesity
    • Flancbaum L, Choban PS, Bradley LR, Burge JC. Changes in measured resting energy expenditure after Roux-en-Y gastric bypass for clinically severe obesity. Surgery 1997; 122:943-949.
    • (1997) Surgery , vol.122 , pp. 943-949
    • Flancbaum, L.1    Choban, P.S.2    Bradley, L.R.3    Burge, J.C.4
  • 49
    • 0028902322 scopus 로고
    • Weight loss and food intake 18 months following vertical banded gastroplasty or gastric bypass for severe obesity
    • Trostler N, Mann A, Zilberbush N, et al. Weight loss and food intake 18 months following vertical banded gastroplasty or gastric bypass for severe obesity. Obes Surg 1995; 5:39-51.
    • (1995) Obes Surg , vol.5 , pp. 39-51
    • Trostler, N.1    Mann, A.2    Zilberbush, N.3
  • 50
    • 0030849844 scopus 로고    scopus 로고
    • Meal size and number: Relationship to dopamine levels in the ventromedial hypothalamic nucleus
    • Meguid MM, Yang ZJ, Laviano A. Meal size and number: relationship to dopamine levels in the ventromedial hypothalamic nucleus. Am J Physiol Regul Integr Comp Physiol 1997; 272:R1925-R1930.
    • (1997) Am J Physiol Regul Integr Comp Physiol , vol.272
    • Meguid, M.M.1    Yang, Z.J.2    Laviano, A.3
  • 51
    • 0029933476 scopus 로고    scopus 로고
    • The gut-brain brain-gut axis in anorexia: Toward an understanding of food intake regulation
    • Meguid MM, Yang ZJ, Gleason JR. The gut-brain brain-gut axis in anorexia: toward an understanding of food intake regulation. Nutrition 1996; 12:S57-S62.
    • (1996) Nutrition , vol.12
    • Meguid, M.M.1    Yang, Z.J.2    Gleason, J.R.3
  • 52
    • 0033166750 scopus 로고    scopus 로고
    • Differential feeding patterns induced by tumor growth and by TPN
    • Meguid MM, Yang ZJ, Gleason JR, Kubota A. Differential feeding patterns induced by tumor growth and by TPN. Nutrition 1999; 15:555-562.
    • (1999) Nutrition , vol.15 , pp. 555-562
    • Meguid, M.M.1    Yang, Z.J.2    Gleason, J.R.3    Kubota, A.4
  • 53
    • 0036906424 scopus 로고    scopus 로고
    • VMN/LHA functional inhibition in tumor-bearing rats suggests hypothalamic involvement in cancer anorexia
    • Laviano A, Meguid MM, Gleason JR, Rossi-Fanelli F. VMN/LHA functional inhibition in tumor-bearing rats suggests hypothalamic involvement in cancer anorexia. Nutr Neurosci 2002; 5:443-456.
    • (2002) Nutr Neurosci , vol.5 , pp. 443-456
    • Laviano, A.1    Meguid, M.M.2    Gleason, J.R.3    Rossi-Fanelli, F.4
  • 54
    • 21044441693 scopus 로고    scopus 로고
    • Sex-related differences in energy balance in response to caloric restriction
    • Valle A, Catala-Niell A, Colom B, et al. Sex-related differences in energy balance in response to caloric restriction. Am J Physiol Endocrinol Metab 2005; 289:E15-E22. Complete and interesting study of the sex-related differences in energy balance in response to caloric restriction, with females shown to deactivate facultative thermogenesis to a greater degree than males.
    • (2005) Am J Physiol Endocrinol Metab , vol.289
    • Valle, A.1    Catala-Niell, A.2    Colom, B.3
  • 55
    • 0033984012 scopus 로고    scopus 로고
    • Metabolic mass, metabolic rate, caloric restriction, and aging in male Fischer 344 rats
    • Greenberg JA, Boozer CN. Metabolic mass, metabolic rate, caloric restriction, and aging in male Fischer 344 rats. Mech Ageing Dev 2000; 113:37-48.
    • (2000) Mech Ageing Dev , vol.113 , pp. 37-48
    • Greenberg, J.A.1    Boozer, C.N.2
  • 56
    • 0020434317 scopus 로고
    • Maintenance energy requirements during lactation in rats
    • Canas R, Romero JJ, Baldwin RL. Maintenance energy requirements during lactation in rats. J Nutr 1982; 112:1876-1880.
    • (1982) J Nutr , vol.112 , pp. 1876-1880
    • Canas, R.1    Romero, J.J.2    Baldwin, R.L.3
  • 57
    • 0018348872 scopus 로고
    • Tissue distribution of cold-induced thermogenesis in conscious warm- or cold-acclimated rats reevaluated from changes in tissue blood flow: The dominant role of brown adipose tissue in the replacement of shivering by nonshivering thermogenesis
    • Foster DO, Frydman ML. Tissue distribution of cold-induced thermogenesis in conscious warm- or cold-acclimated rats reevaluated from changes in tissue blood flow: the dominant role of brown adipose tissue in the replacement of shivering by nonshivering thermogenesis. Can J Physiol Pharmacol 1979; 57:257-270.
    • (1979) Can J Physiol Pharmacol , vol.57 , pp. 257-270
    • Foster, D.O.1    Frydman, M.L.2
  • 59
    • 0034504237 scopus 로고    scopus 로고
    • Subcutaneous and visceral adipose tissue: Their relation to the metabolic syndrome
    • Wajchenberg BL. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev 2000; 21:697-738.
    • (2000) Endocr Rev , vol.21 , pp. 697-738
    • Wajchenberg, B.L.1
  • 60
    • 0026466915 scopus 로고
    • The morphology and metabolism of intraabdominal adipose tissue in men
    • Marin P, Andersson B, Ottosson M, et al. The morphology and metabolism of intraabdominal adipose tissue in men. Metabolism 1992; 41:1242-1248.
    • (1992) Metabolism , vol.41 , pp. 1242-1248
    • Marin, P.1    Andersson, B.2    Ottosson, M.3
  • 62
    • 0037569480 scopus 로고    scopus 로고
    • Resistin: Molecular history and prognosis
    • Banerjee RR, Lazar MA. Resistin: molecular history and prognosis. J Mol Med 2003; 81:218-226.
    • (2003) J Mol Med , vol.81 , pp. 218-226
    • Banerjee, R.R.1    Lazar, M.A.2
  • 63
    • 0025292829 scopus 로고
    • The response to long-term overfeeding in identical twins
    • Bouchard C, Tremblay A, Despres JP, et al. The response to long-term overfeeding in identical twins. N Engl J Med 1990; 322:1477-1482.
    • (1990) N Engl J Med , vol.322 , pp. 1477-1482
    • Bouchard, C.1    Tremblay, A.2    Despres, J.P.3
  • 64
    • 0002554440 scopus 로고    scopus 로고
    • Methodological and clinical aspects of subcutaneous fat distribution
    • Angel, A, Anderson, H, Bouchard, C, et al., editors. Toronto, Canada, 20-25 August 1994. London: John Libbey & Company
    • Zamboni M, Armellini F, Muller D, et al. Methodological and clinical aspects of subcutaneous fat distribution. In: Angel, A, Anderson, H, Bouchard, C, et al., editors. Progress in obesity research: Proceedings of the Seventh International Congress on Obesity, Toronto, Canada, 20-25 August 1994. London: John Libbey & Company; 1996. pp. 145-150.
    • (1996) Progress in Obesity Research: Proceedings of the Seventh International Congress on Obesity , pp. 145-150
    • Zamboni, M.1    Armellini, F.2    Muller, D.3
  • 65
    • 0030279888 scopus 로고    scopus 로고
    • Effect of regain of body weight on regional body fat distribution: Comparison between pre- and postmenopausal obese women
    • Zamboni M, Armellini F, Turcato E, et al. Effect of regain of body weight on regional body fat distribution: comparison between pre- and postmenopausal obese women. Obes Res 1996; 4:555-560.
    • (1996) Obes Res , vol.4 , pp. 555-560
    • Zamboni, M.1    Armellini, F.2    Turcato, E.3
  • 66
    • 18144408371 scopus 로고    scopus 로고
    • Adipose tissue, adipokines, and inflammation
    • Fantuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 2005; 115:911-919. This review summarizes the mechanisms of action and the role played by the adipokines and cytokines in obesity, diabetes and inflammation.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 911-919
    • Fantuzzi, G.1
  • 67
    • 29244476240 scopus 로고    scopus 로고
    • Adipocytokines: Leptin - The classical, resistin - The controversical, adiponectin - The promising, and more to come
    • Koerner A, Kratzsch J, Kiess W. Adipocytokines: leptin - the classical, resistin - the controversical, adiponectin - the promising, and more to come. Best Pract Res Clin Endocrinol Metab 2005; 19:525-546.
    • (2005) Best Pract Res Clin Endocrinol Metab , vol.19 , pp. 525-546
    • Koerner, A.1    Kratzsch, J.2    Kiess, W.3
  • 68
    • 2342537773 scopus 로고    scopus 로고
    • From blood monocytes to adipose tissue-resident macrophages: Induction of diapedesis by human mature adipocytes
    • Curat CA, Miranville A, Sengenes C, et al. From blood monocytes to adipose tissue-resident macrophages: induction of diapedesis by human mature adipocytes. Diabetes 2004; 53:1285-1292.
    • (2004) Diabetes , vol.53 , pp. 1285-1292
    • Curat, C.A.1    Miranville, A.2    Sengenes, C.3
  • 69
    • 0036894201 scopus 로고    scopus 로고
    • Y2 receptor deletion attenuates the type 2 diabetic syndrome of ob/ob mice
    • Sainsbury A, Schwarzer C, Couzens M, Herzog H. Y2 receptor deletion attenuates the type 2 diabetic syndrome of ob/ob mice. Diabetes 2002; 51:3420-3427.
    • (2002) Diabetes , vol.51 , pp. 3420-3427
    • Sainsbury, A.1    Schwarzer, C.2    Couzens, M.3    Herzog, H.4
  • 70
    • 0035851851 scopus 로고    scopus 로고
    • The hypothalamus and the control of energy homeostasis: Different circuits, different purposes
    • Williams G, Bing C, Cai XJ, et al. The hypothalamus and the control of energy homeostasis: different circuits, different purposes. Physiol Behav 2001; 74:683-701.
    • (2001) Physiol Behav , vol.74 , pp. 683-701
    • Williams, G.1    Bing, C.2    Cai, X.J.3
  • 71
    • 0031630387 scopus 로고    scopus 로고
    • Ventromedial nucleus of hypothalamus is related to the development of cancer-induced anorexia: In vivo microdialysis study
    • Hradec Kralove
    • Blaha V, Yang ZJ, Meguid MM, et al. Ventromedial nucleus of hypothalamus is related to the development of cancer-induced anorexia: in vivo microdialysis study. Acta Medica (Hradec Kralove) 1998; 41:3-11.
    • (1998) Acta Medica , vol.41 , pp. 3-11
    • Blaha, V.1    Yang, Z.J.2    Meguid, M.M.3
  • 72
    • 20444379263 scopus 로고    scopus 로고
    • Normalization of hypothalamic serotonin (5-HT 1B) receptor and NPY in cancer anorexia after tumor resection: An immunocytochemical study
    • Makarenko IG, Meguid MM, Gatto L, et al. Normalization of hypothalamic serotonin (5-HT 1B) receptor and NPY in cancer anorexia after tumor resection: an immunocytochemical study. Neurosci Lett 2005; 383:322-327.
    • (2005) Neurosci Lett , vol.383 , pp. 322-327
    • Makarenko, I.G.1    Meguid, M.M.2    Gatto, L.3
  • 73
    • 1942516505 scopus 로고    scopus 로고
    • Tumor anorexia: Effects on neuropeptide Y and monoamines in paraventricular nucleus
    • Meguid MM, Ramos EJ, Laviano A, et al. Tumor anorexia: effects on neuropeptide Y and monoamines in paraventricular nucleus. Peptides 2004; 25:261-266.
    • (2004) Peptides , vol.25 , pp. 261-266
    • Meguid, M.M.1    Ramos, E.J.2    Laviano, A.3
  • 74
    • 0030936556 scopus 로고    scopus 로고
    • Does central obesity reflect 'Cushing's disease of the omentum'?
    • Bujalska IJ, Kumar S, Stewart PM. Does central obesity reflect 'Cushing's disease of the omentum'? Lancet 1997; 349:1210-1213.
    • (1997) Lancet , vol.349 , pp. 1210-1213
    • Bujalska, I.J.1    Kumar, S.2    Stewart, P.M.3
  • 76
    • 0032776071 scopus 로고    scopus 로고
    • Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3
    • de Jong EC, Vieira PL, Kalinski P, Kapsenberg ML. Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3. J Leukoc Biol 1999; 66:201-204.
    • (1999) J Leukoc Biol , vol.66 , pp. 201-204
    • De Jong, E.C.1    Vieira, P.L.2    Kalinski, P.3    Kapsenberg, M.L.4
  • 77
    • 0029859099 scopus 로고    scopus 로고
    • Leptin: The tale of an obesity gene
    • Caro JF, Sinha MK, Kolaczynski JW, et al. Leptin: the tale of an obesity gene. Diabetes 1996; 45:1455-1462.
    • (1996) Diabetes , vol.45 , pp. 1455-1462
    • Caro, J.F.1    Sinha, M.K.2    Kolaczynski, J.W.3
  • 78
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • Maffei M, Halaas J, Ravussin E, et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1995; 1:1155-1161.
    • (1995) Nat Med , vol.1 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3
  • 79
    • 0029844267 scopus 로고    scopus 로고
    • Effect of fasting on serum leptin in normal human subjects
    • Boden G, Chen X, Mozzoli M, Ryan I. Effect of fasting on serum leptin in normal human subjects. J Clin Endocrinol Metab 1996; 81:3419-3423.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3419-3423
    • Boden, G.1    Chen, X.2    Mozzoli, M.3    Ryan, I.4
  • 80
    • 0029166158 scopus 로고
    • Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (oblob) mice
    • Trayhurn P, Thomas ME, Duncan JS, Rayner DV. Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (oblob) mice. FEBS Lett 1995; 368:488-490.
    • (1995) FEBS Lett , vol.368 , pp. 488-490
    • Trayhurn, P.1    Thomas, M.E.2    Duncan, J.S.3    Rayner, D.V.4
  • 81
    • 0033515761 scopus 로고    scopus 로고
    • Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
    • Arita Y, Kihara S, Ouchi N, et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999; 257:79-83.
    • (1999) Biochem Biophys Res Commun , vol.257 , pp. 79-83
    • Arita, Y.1    Kihara, S.2    Ouchi, N.3
  • 82
    • 0035663963 scopus 로고    scopus 로고
    • Endogenous glucose production is inhibited by the adipose-derived protein Acrp30
    • Combs TP, Berg AH, Obici S, et al. Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. J Clin Invest 2001; 108:1875-1881.
    • (2001) J Clin Invest , vol.108 , pp. 1875-1881
    • Combs, T.P.1    Berg, A.H.2    Obici, S.3
  • 83
    • 0037059013 scopus 로고    scopus 로고
    • Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
    • U S A
    • Tomas E, Tsao TS, Saha AK, et al. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci U S A 2002; 99:16309-16313.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 16309-16313
    • Tomas, E.1    Tsao, T.S.2    Saha, A.K.3
  • 84
    • 0035905758 scopus 로고    scopus 로고
    • The hormone resistin links obesity to diabetes
    • Steppan CM, Bailey ST, Bhat S, et al. The hormone resistin links obesity to diabetes. Nature 2001; 409:307-312.
    • (2001) Nature , vol.409 , pp. 307-312
    • Steppan, C.M.1    Bailey, S.T.2    Bhat, S.3
  • 85
    • 10744225368 scopus 로고    scopus 로고
    • Regulation of fasted blood glucose by resistin
    • Banerjee RR, Rangwala SM, Shapiro JS, et al. Regulation of fasted blood glucose by resistin. Science 2004; 303:1195-1198.
    • (2004) Science , vol.303 , pp. 1195-1198
    • Banerjee, R.R.1    Rangwala, S.M.2    Shapiro, J.S.3
  • 86
    • 14844320127 scopus 로고    scopus 로고
    • Cancer anorexia-cachexia syndrome: Cytokines and neuropeptides
    • Ramos EJ, Suzuki S, Marks D, et al. Cancer anorexia-cachexia syndrome: cytokines and neuropeptides. Curr Opin Clin Nutr Metab Care 2004; 7:427-434.
    • (2004) Curr Opin Clin Nutr Metab Care , vol.7 , pp. 427-434
    • Ramos, E.J.1    Suzuki, S.2    Marks, D.3
  • 87
  • 88
    • 0036789186 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha stimulates lipolysis in differentiated human adipocytes through activation of extracellular signal-related kinase and elevation of intracellular cAMP
    • Zhang HH, Halbleib M, Ahmad F, et al. Tumor necrosis factor-alpha stimulates lipolysis in differentiated human adipocytes through activation of extracellular signal-related kinase and elevation of intracellular cAMP. Diabetes 2002; 51:2929-2935.
    • (2002) Diabetes , vol.51 , pp. 2929-2935
    • Zhang, H.H.1    Halbleib, M.2    Ahmad, F.3
  • 89
    • 8744267483 scopus 로고    scopus 로고
    • Interleukin-6 regulates human adipose tissue lipid metabolism and leptin production in vitro
    • Trujillo ME, Sullivan S, Harten I, et al. Interleukin-6 regulates human adipose tissue lipid metabolism and leptin production in vitro. J Clin Endocrinol Metab 2004; 89:5577-5582.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 5577-5582
    • Trujillo, M.E.1    Sullivan, S.2    Harten, I.3
  • 90
    • 0038372035 scopus 로고    scopus 로고
    • Interleukin-6 stimulates lipolysis and fat oxidation in humans
    • van Hall G, Steensberg A, Sacchetti M, et al. Interleukin-6 stimulates lipolysis and fat oxidation in humans. J Clin Endocrinol Metab 2003; 88:3005-3010.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3005-3010
    • Van Hall, G.1    Steensberg, A.2    Sacchetti, M.3
  • 91
    • 0036152683 scopus 로고    scopus 로고
    • Interleukin-6-deficient mice develop mature-onset obesity
    • Wallenius V, Wallenius K, Ahren B, et al. Interleukin-6-deficient mice develop mature-onset obesity. Nat Med 2002; 8:75-79.
    • (2002) Nat Med , vol.8 , pp. 75-79
    • Wallenius, V.1    Wallenius, K.2    Ahren, B.3
  • 92
    • 0036295573 scopus 로고    scopus 로고
    • Intracerebroventricular interleukin-6 treatment decreases body fat in rats
    • Wallenius K, Wallenius V, Sunter D, et al. Intracerebroventricular interleukin-6 treatment decreases body fat in rats. Biochem Biophys Res Commun 2002; 293:560-565.
    • (2002) Biochem Biophys Res Commun , vol.293 , pp. 560-565
    • Wallenius, K.1    Wallenius, V.2    Sunter, D.3
  • 93
    • 0035758109 scopus 로고    scopus 로고
    • Peripheral signals conveying metabolic information to the brain: Short-term and long-term regulation of food intake and energy homeostasis
    • Maywood
    • Havel PJ. Peripheral signals conveying metabolic information to the brain: short-term and long-term regulation of food intake and energy homeostasis. Exp Biol Med (Maywood) 2001; 226:963-977.
    • (2001) Exp Biol Med , vol.226 , pp. 963-977
    • Havel, P.J.1
  • 94
    • 32944470975 scopus 로고    scopus 로고
    • Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety
    • Borg CM, le Roux CW, Ghatei MA, et al. Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety. Br J Surg 2006; 93:210-215. An important study investigating the prospective changes in gut hormones and metabolic indices after RYGB. The authors suggest gut adaptation and the consequent graded rise in the levels of gut hormones that promote satiety account for the lack of the expected increase in food intake.
    • (2006) Br J Surg , vol.93 , pp. 210-215
    • Borg, C.M.1    Le Roux, C.W.2    Ghatei, M.A.3
  • 95
    • 17744406984 scopus 로고    scopus 로고
    • Abstracts of the 2003 NAASO (North American Association for the Study of Obesity) annual meeting. October 11-15, 2003. Ft. Lauderdale, Florida, USA
    • Abstracts of the 2003 NAASO (North American Association for the Study of Obesity) annual meeting. October 11-15, 2003. Ft. Lauderdale, Florida, USA. Obes Res 2003; 11 (Suppl).
    • (2003) Obes Res , vol.11 , Issue.SUPPL.
  • 96
    • 0037325191 scopus 로고    scopus 로고
    • Ghrelin: A gut-brain hormone: Effect of gastric bypass surgery
    • Geloneze B, Tambascia MA, Pilla VF, et al. Ghrelin: a gut-brain hormone: effect of gastric bypass surgery. Obes Surg 2003; 13:17-22.
    • (2003) Obes Surg , vol.13 , pp. 17-22
    • Geloneze, B.1    Tambascia, M.A.2    Pilla, V.F.3
  • 97
    • 0141676021 scopus 로고    scopus 로고
    • Different plasma ghrelin levels after laparoscopic gastric bypass and adjustable gastric banding in morbid obese subjects
    • Leonetti F, Silecchia G, Iacobellis G, et al. Different plasma ghrelin levels after laparoscopic gastric bypass and adjustable gastric banding in morbid obese subjects. J Clin Endocrinol Metab 2003; 88:4227-4231.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4227-4231
    • Leonetti, F.1    Silecchia, G.2    Iacobellis, G.3
  • 98
    • 1642275315 scopus 로고    scopus 로고
    • Serum ghrelin levels in response to glucose load in obese subjects post-gastric bypass surgery
    • Tritos NA, Mun E, Bertkau A, et al. Serum ghrelin levels in response to glucose load in obese subjects post-gastric bypass surgery. Obes Res 2003; 11:919-924.
    • (2003) Obes Res , vol.11 , pp. 919-924
    • Tritos, N.A.1    Mun, E.2    Bertkau, A.3
  • 99
    • 0035133586 scopus 로고    scopus 로고
    • Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin
    • Asakawa A, Inui A, Kaga T, et al. Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin. Gastroenterology 2001; 120:337-345.
    • (2001) Gastroenterology , vol.120 , pp. 337-345
    • Asakawa, A.1    Inui, A.2    Kaga, T.3
  • 100
    • 0033679897 scopus 로고    scopus 로고
    • Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans
    • Date Y, Kojima M, Hosoda H, et al. Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 2000; 141:4255-4261.
    • (2000) Endocrinology , vol.141 , pp. 4255-4261
    • Date, Y.1    Kojima, M.2    Hosoda, H.3
  • 101
    • 19944433652 scopus 로고    scopus 로고
    • Visfatin: A protein secreted by visceral fat that mimics the effects of insulin
    • Fukuhara A, Matsuda M, Nishizawa M, et al. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 2005; 307:426-430.
    • (2005) Science , vol.307 , pp. 426-430
    • Fukuhara, A.1    Matsuda, M.2    Nishizawa, M.3
  • 102
    • 0035099753 scopus 로고    scopus 로고
    • Ghrelin, a novel placental-derived hormone
    • Gualillo O, Caminos J, Blanco M, et al. Ghrelin, a novel placental-derived hormone. Endocrinology 2001; 142:788-794.
    • (2001) Endocrinology , vol.142 , pp. 788-794
    • Gualillo, O.1    Caminos, J.2    Blanco, M.3
  • 104
    • 0034609952 scopus 로고    scopus 로고
    • Ghrelin stimulates gastric acid secretion and motility in rats
    • Masuda Y, Tanaka T, Inomata N, et al. Ghrelin stimulates gastric acid secretion and motility in rats. Biochem Biophys Res Commun 2000; 276:905-908.
    • (2000) Biochem Biophys Res Commun , vol.276 , pp. 905-908
    • Masuda, Y.1    Tanaka, T.2    Inomata, N.3
  • 105
    • 0034672457 scopus 로고    scopus 로고
    • Kidney produces a novel acylated peptide, ghrelin
    • Mori K, Yoshimoto A, Takaya K, et al. Kidney produces a novel acylated peptide, ghrelin. FEBS Lett 2000; 486:213-216.
    • (2000) FEBS Lett , vol.486 , pp. 213-216
    • Mori, K.1    Yoshimoto, A.2    Takaya, K.3
  • 106
    • 0041859261 scopus 로고    scopus 로고
    • Inhibition of food intake in obese subjects by peptide YY3-36
    • Batterham RL, Cohen MA, Ellis SM, et al. Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med 2003; 349:941-948.
    • (2003) N Engl J Med , vol.349 , pp. 941-948
    • Batterham, R.L.1    Cohen, M.A.2    Ellis, S.M.3
  • 107
    • 0028148456 scopus 로고
    • Peptide YY augments postprandial small intestinal absorption in the conscious dog
    • Bilchik AJ, Hines OJ, Zinner MJ, et al. Peptide YY augments postprandial small intestinal absorption in the conscious dog. Am J Surg 1994; 167:570-574.
    • (1994) Am J Surg , vol.167 , pp. 570-574
    • Bilchik, A.J.1    Hines, O.J.2    Zinner, M.J.3
  • 108
    • 0027941875 scopus 로고
    • Peptide YY immunoneutralization inhibits meal-induced absorption in vivo
    • Bilchik AJ, Hines OJ, Ashley SW, et al. Peptide YY immunoneutralization inhibits meal-induced absorption in vivo. Surgery 1994; 116:1153-1157.
    • (1994) Surgery , vol.116 , pp. 1153-1157
    • Bilchik, A.J.1    Hines, O.J.2    Ashley, S.W.3
  • 109
    • 0029950236 scopus 로고    scopus 로고
    • Peptide YY: A potential proabsorptive hormone for the treatment of malabsorptive disorders
    • Liu CD, Aloia T, Adrian TE, et al. Peptide YY: a potential proabsorptive hormone for the treatment of malabsorptive disorders. Am Surg 1996; 62:232-236.
    • (1996) Am Surg , vol.62 , pp. 232-236
    • Liu, C.D.1    Aloia, T.2    Adrian, T.E.3
  • 110
    • 0031732386 scopus 로고    scopus 로고
    • An increase in mucosal insulin-like growth factor II content in postresectional rat intestine suggests autocrine or paracrine growth stimulation
    • Wiren M, Adrian TE, Arnelo U, et al. An increase in mucosal insulin-like growth factor II content in postresectional rat intestine suggests autocrine or paracrine growth stimulation. Scand J Gastroenterol 1998; 33:1080-1086.
    • (1998) Scand J Gastroenterol , vol.33 , pp. 1080-1086
    • Wiren, M.1    Adrian, T.E.2    Arnelo, U.3
  • 111
    • 0037043704 scopus 로고    scopus 로고
    • Gut hormone PYY(S-36) physiologically inhibits food intake
    • Batterham RL, Cowley MA, Small CJ, et al. Gut hormone PYY(S-36) physiologically inhibits food intake. Nature 2002; 418:650-654.
    • (2002) Nature , vol.418 , pp. 650-654
    • Batterham, R.L.1    Cowley, M.A.2    Small, C.J.3
  • 113
    • 31544480051 scopus 로고    scopus 로고
    • PYY[3-36] administration decreases the respiratory quotient and reduces adiposity in diet-induced obese mice
    • 3-36 induces a negative energy balance by reducing food intake and increasing mobilization of fat stores. These effects are relevant for a better understanding of the mechanisms involved in RYGB-induced catabolism and weight loss.
    • (2006) J Nutr , vol.136 , pp. 195-201
    • Adams, S.H.1    Lei, C.2    Jodka, C.M.3
  • 114
    • 0035843183 scopus 로고    scopus 로고
    • A role for ghrelin in the central regulation of feeding
    • Nakazato M, Murakami N, Date Y, et al. A role for ghrelin in the central regulation of feeding. Nature 2001; 409:194-198.
    • (2001) Nature , vol.409 , pp. 194-198
    • Nakazato, M.1    Murakami, N.2    Date, Y.3
  • 115
    • 0034522843 scopus 로고    scopus 로고
    • Central effect of ghrelin, an endogenous growth hormone secretagogue, on hypothalamic peptide gene expression
    • Kamegai J, Tamura H, Shimizu T, et al. Central effect of ghrelin, an endogenous growth hormone secretagogue, on hypothalamic peptide gene expression. Endocrinology 2000; 141:4797-4800.
    • (2000) Endocrinology , vol.141 , pp. 4797-4800
    • Kamegai, J.1    Tamura, H.2    Shimizu, T.3
  • 116
    • 0035942777 scopus 로고    scopus 로고
    • Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
    • Cowley MA, Smart JL, Rubinstein M, et al. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 2001; 411:480-484.
    • (2001) Nature , vol.411 , pp. 480-484
    • Cowley, M.A.1    Smart, J.L.2    Rubinstein, M.3
  • 117
    • 33645882953 scopus 로고    scopus 로고
    • Comparative analysis of the effects of ghrelin and un-acylated ghrelin upon luteinizing hormone secretion in male rats
    • Martini AC, Fernandez-Fernandez R, Tovar S, et al. Comparative analysis of the effects of ghrelin and un-acylated ghrelin upon luteinizing hormone secretion in male rats. Endocrinology 2006; 147:2374-2382.
    • (2006) Endocrinology , vol.147 , pp. 2374-2382
    • Martini, A.C.1    Fernandez-Fernandez, R.2    Tovar, S.3
  • 118
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature 2000; 407:908-913.
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 119
    • 0034649219 scopus 로고    scopus 로고
    • Leptin resistance of adipocytes in obesity: Role of suppressors of cytokine signaling
    • Wang Z, Zhou YT, Kakuma T, et al. Leptin resistance of adipocytes in obesity: role of suppressors of cytokine signaling. Biochem Biophys Res Commun 2000; 277:20-26.
    • (2000) Biochem Biophys Res Commun , vol.277 , pp. 20-26
    • Wang, Z.1    Zhou, Y.T.2    Kakuma, T.3
  • 120
    • 0037423693 scopus 로고    scopus 로고
    • Anti-cachectic effect of ghrelin in nude mice bearing human melanoma cells
    • Hanada T, Toshinai K, Kajimura N, et al. Anti-cachectic effect of ghrelin in nude mice bearing human melanoma cells. Biochem Biophys Res Commun 2003; 301:275-279.
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 275-279
    • Hanada, T.1    Toshinai, K.2    Kajimura, N.3
  • 121
    • 0346685842 scopus 로고    scopus 로고
    • Upregulation of ghrelin expression in cachectic nude mice bearing human melanoma cells
    • Hanada T, Toshinai K, Date Y, et al. Upregulation of ghrelin expression in cachectic nude mice bearing human melanoma cells. Metabolism 2004; 53:84-88.
    • (2004) Metabolism , vol.53 , pp. 84-88
    • Hanada, T.1    Toshinai, K.2    Date, Y.3
  • 122
    • 0035089767 scopus 로고    scopus 로고
    • Minireview: Neuroprotective effects of estrogen: New insights into mechanisms of action
    • Wise PM, Dubal DB, Wilson ME, et al. Minireview: neuroprotective effects of estrogen: new insights into mechanisms of action. Endocrinology 2001; 142:969-973.
    • (2001) Endocrinology , vol.142 , pp. 969-973
    • Wise, P.M.1    Dubal, D.B.2    Wilson, M.E.3
  • 123
    • 0035908954 scopus 로고    scopus 로고
    • Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure
    • Nagaya N, Uematsu M, Kojima M, et al. Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure. Circulation 2001; 104:1430-1435.
    • (2001) Circulation , vol.104 , pp. 1430-1435
    • Nagaya, N.1    Uematsu, M.2    Kojima, M.3
  • 124
    • 0037212072 scopus 로고    scopus 로고
    • Habitual binge/purge behavior influences circulating ghrelin levels in eating disorders
    • Tanaka M, Naruo T, Nagai N, et al. Habitual binge/purge behavior influences circulating ghrelin levels in eating disorders. J Psychiatr Res 2003; 37:17-22.
    • (2003) J Psychiatr Res , vol.37 , pp. 17-22
    • Tanaka, M.1    Naruo, T.2    Nagai, N.3
  • 125
    • 0037314839 scopus 로고    scopus 로고
    • Increased plasma ghrelin level in lung cancer cachexia
    • Shimizu Y, Nagaya N, Isobe T, et al. Increased plasma ghrelin level in lung cancer cachexia. Clin Cancer Res 2003; 9:774-778.
    • (2003) Clin Cancer Res , vol.9 , pp. 774-778
    • Shimizu, Y.1    Nagaya, N.2    Isobe, T.3
  • 126
    • 0037462298 scopus 로고    scopus 로고
    • Decreased NPY innervation of the hypothalamic nuclei in rats with cancer anorexia
    • Makarenko IG, Meguid MM, Gatto L, et al. Decreased NPY innervation of the hypothalamic nuclei in rats with cancer anorexia. Brain Res 2003; 961:100-108.
    • (2003) Brain Res , vol.961 , pp. 100-108
    • Makarenko, I.G.1    Meguid, M.M.2    Gatto, L.3
  • 127
    • 13444306584 scopus 로고    scopus 로고
    • Hypothalamic 5-HT1 B-receptor changes in anorectic tumor bearing rats
    • Makarenko IG, Meguid MM, Gatto L, et al. Hypothalamic 5-HT1 B-receptor changes in anorectic tumor bearing rats. Neurosci Lett 2005; 376:71-75.
    • (2005) Neurosci Lett , vol.376 , pp. 71-75
    • Makarenko, I.G.1    Meguid, M.M.2    Gatto, L.3
  • 128
    • 0344826046 scopus 로고    scopus 로고
    • Integration of hypothalamic feeding and metabolic signals: Focus on neuropeptide Y
    • Currie PJ. Integration of hypothalamic feeding and metabolic signals: focus on neuropeptide Y. Appetite 2003; 41:335-337.
    • (2003) Appetite , vol.41 , pp. 335-337
    • Currie, P.J.1
  • 129
    • 0028847195 scopus 로고
    • The serotonin (5-HT) antagonist methysergide increases neuropeptide Y (NPY) synthesis and secretion in the hypothalamus of the rat
    • Dryden S, Wang Q, Frankish HM, et al. The serotonin (5-HT) antagonist methysergide increases neuropeptide Y (NPY) synthesis and secretion in the hypothalamus of the rat. Brain Res 1995; 699:12-18.
    • (1995) Brain Res , vol.699 , pp. 12-18
    • Dryden, S.1    Wang, Q.2    Frankish, H.M.3
  • 130
    • 0032400808 scopus 로고    scopus 로고
    • Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight
    • Grill HJ, Ginsberg AB, Seeley RJ, Kaplan JM. Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight. J Neurosci 1998; 18:10128-10135.
    • (1998) J Neurosci , vol.18 , pp. 10128-10135
    • Grill, H.J.1    Ginsberg, A.B.2    Seeley, R.J.3    Kaplan, J.M.4
  • 131
    • 31544474029 scopus 로고    scopus 로고
    • Interactions between the melanocortin system and the hypothalamo- pituitary-thyroid axis
    • Martin NM, Smith KL, Bloom SR, Small CJ. Interactions between the melanocortin system and the hypothalamo-pituitary-thyroid axis. Peptides 2006; 27:333-339.
    • (2006) Peptides , vol.27 , pp. 333-339
    • Martin, N.M.1    Smith, K.L.2    Bloom, S.R.3    Small, C.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.