메뉴 건너뛰기




Volumn 2, Issue 2, 2006, Pages 127-135

Epigenetic therapies of cancer

Author keywords

DNA methylation; DNA methyl transferase inhibitors; Epigenetics; Histone deacetylase inhibitors; Histone modification; SWI SNF complexes

Indexed keywords

3 PHENYLSULFAMOYLCINNAMOHYDROXAMIC ACID; 4 [N (2 HYDROXYETHYL) N [2 (3 INDOLYL)ETHYL]AMINOMETHYL]CINNAMOHYDROXAMIC ACID; 4 N ACETYLDINALINE; 5 AZA 2' DEOXYCYTIDINE; ADENOSINE TRIPHOSPHATE; ANACARDIC ACID; ANTISENSE OLIGONUCLEOTIDE; APICIDIN; AZACITIDINE; BUTYRIC ACID DERIVATIVE; COENZYME A; CURCUMIN; DEPSIPEPTIDE; DNA; EPIGALLOCATECHIN GALLATE; GEMCITABINE; HISTONE; HISTONE DEACETYLASE INHIBITOR; LYSINE; LYSYL COENZYME A; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE; OXAMFLATIN; PROCAINAMIDE; PROCAINE; TRAPOXIN; TRICHOSTATIN A; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; VORINOSTAT; ZEBULARINE;

EID: 33746140967     PISSN: 15733947     EISSN: None     Source Type: Journal    
DOI: 10.2174/157339406776872816     Document Type: Review
Times cited : (3)

References (95)
  • 1
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T, Allis CD. Translating the histone code. Science 2001; 293: 1074-80.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 2
    • 0034905043 scopus 로고    scopus 로고
    • The human melanocyte: A model system to study the complexity of cellular aging and transformation in non-fibroblastic cells
    • Bandyopadhyay D, Timchenko N, Suwa T, Hornsby PJ, Campisi J, Medrano EE. The human melanocyte: a model system to study the complexity of cellular aging and transformation in non-fibroblastic cells. Exp Gerontol 2001; 36: 1265-75.
    • (2001) Exp Gerontol , vol.36 , pp. 1265-1275
    • Bandyopadhyay, D.1    Timchenko, N.2    Suwa, T.3    Hornsby, P.J.4    Campisi, J.5    Medrano, E.E.6
  • 3
    • 6044256118 scopus 로고    scopus 로고
    • Histones and histone modifications
    • Peterson CL, Laniel MA. Histones and histone modifications. Curr Biol 2004; 14: R546-R551.
    • (2004) Curr Biol , vol.14
    • Peterson, C.L.1    Laniel, M.A.2
  • 4
    • 85015069067 scopus 로고    scopus 로고
    • Controlling the double helix
    • Felsenfeld G, Groudine M. Controlling the double helix. Nature 2003; 421: 448-53.
    • (2003) Nature , vol.421 , pp. 448-453
    • Felsenfeld, G.1    Groudine, M.2
  • 5
    • 0842324785 scopus 로고    scopus 로고
    • The nucleosome: From genomic organization to genomic regulation
    • Khorasanizadeh S. The nucleosome: from genomic organization to genomic regulation. Cell 2004; 116: 259-72.
    • (2004) Cell , vol.116 , pp. 259-272
    • Khorasanizadeh, S.1
  • 6
    • 0032142918 scopus 로고    scopus 로고
    • Roles of histone acetyltransferases and deacetylases in gene regulation
    • Kuo MH, Allis CD. Roles of histone acetyltransferases and deacetylases in gene regulation. Bioessays 1998; 20: 615-26.
    • (1998) Bioessays , vol.20 , pp. 615-626
    • Kuo, M.H.1    Allis, C.D.2
  • 7
    • 4143089466 scopus 로고    scopus 로고
    • Implications of small molecule activators and inhibitors of histone acetyltransferases in chromatin therapy
    • Varier RA, Swaminathan V, Balasubramanyam K, Kundu TK. Implications of small molecule activators and inhibitors of histone acetyltransferases in chromatin therapy. Biochem Pharmacol 2004; 68: 1215-20.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1215-1220
    • Varier, R.A.1    Swaminathan, V.2    Balasubramanyam, K.3    Kundu, T.K.4
  • 9
    • 0034632829 scopus 로고    scopus 로고
    • Regulation of chromatin structure by site-specific histone H3 methyltransferases
    • Rea S, Eisenhaber F, O'Carroll D, et al. Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 2000; 406: 593-9.
    • (2000) Nature , vol.406 , pp. 593-599
    • Rea, S.1    Eisenhaber, F.2    O'Carroll, D.3
  • 10
    • 0242348752 scopus 로고    scopus 로고
    • Histone lysine methylation: A signature for chromatin function
    • Sims RJ, III, Nishioka K, Reinberg D. Histone lysine methylation: a signature for chromatin function. Trends Genet 2003; 19: 629-39.
    • (2003) Trends Genet , vol.19 , pp. 629-639
    • Sims III, R.J.1    Nishioka, K.2    Reinberg, D.3
  • 11
    • 0037172665 scopus 로고    scopus 로고
    • Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain
    • Feng Q, Wang H, Ng HH, et al. Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain. Curr Biol 2002; 12: 1052-8.
    • (2002) Curr Biol , vol.12 , pp. 1052-1058
    • Feng, Q.1    Wang, H.2    Ng, H.H.3
  • 12
    • 14844307097 scopus 로고    scopus 로고
    • Epigenetic regulation by histone methylation and histone variants
    • Cheung P, Lau P. Epigenetic regulation by histone methylation and histone variants. Mol Endocrinol 2005; 19: 563-73.
    • (2005) Mol Endocrinol , vol.19 , pp. 563-573
    • Cheung, P.1    Lau, P.2
  • 13
    • 11144332565 scopus 로고    scopus 로고
    • Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
    • Shi Y, Lan F, Matson C, et al. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 2004; 119: 941-53.
    • (2004) Cell , vol.119 , pp. 941-953
    • Shi, Y.1    Lan, F.2    Matson, C.3
  • 14
    • 24944535335 scopus 로고    scopus 로고
    • Regulation of LSD1 histone demethylase activity by its associated factors
    • Shi YJ, Matson C, Lan F, Iwase S, Baba T, Shi Y. Regulation of LSD1 histone demethylase activity by its associated factors. Mol Cell 2005; 19: 857-64.
    • (2005) Mol Cell , vol.19 , pp. 857-864
    • Shi, Y.J.1    Matson, C.2    Lan, F.3    Iwase, S.4    Baba, T.5    Shi, Y.6
  • 15
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002; 16: 6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 16
    • 0034176798 scopus 로고    scopus 로고
    • DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
    • Baylin SB, Herman JG. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 2000; 16; 168-74.
    • (2000) Trends Genet , vol.16 , pp. 168-174
    • Baylin, S.B.1    Herman, J.G.2
  • 17
    • 0020627846 scopus 로고
    • Hypomethylation of ras oncogenes in primary human cancers
    • Feinberg AP, Vogelstein B. Hypomethylation of ras oncogenes in primary human cancers. Biochem Biophys Res Commun 1983; 111: 47-54.
    • (1983) Biochem Biophys Res Commun , vol.111 , pp. 47-54
    • Feinberg, A.P.1    Vogelstein, B.2
  • 18
    • 0027239823 scopus 로고
    • Bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia
    • Hanada M, Delia D, Aiello A, Stadtmauer E, Reed JC. bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. Blood 1993; 82: 1820-8.
    • (1993) Blood , vol.82 , pp. 1820-1828
    • Hanada, M.1    Delia, D.2    Aiello, A.3    Stadtmauer, E.4    Reed, J.C.5
  • 19
    • 1042263110 scopus 로고    scopus 로고
    • Promoter methylation of cyclin D2 gene in gastric carcinoma
    • Oshimo Y, Nakayama H, Ito R, et al. Promoter methylation of cyclin D2 gene in gastric carcinoma. Int J Oncol 2003; 23: 1663-70.
    • (2003) Int J Oncol , vol.23 , pp. 1663-1670
    • Oshimo, Y.1    Nakayama, H.2    Ito, R.3
  • 20
    • 0037068372 scopus 로고    scopus 로고
    • DNA methylation and chromatin - Unraveling the tangled web
    • Robertson KD. DNA methylation and chromatin - unraveling the tangled web. Oncogene 2002; 21: 5361-79.
    • (2002) Oncogene , vol.21 , pp. 5361-5379
    • Robertson, K.D.1
  • 21
    • 5644255995 scopus 로고    scopus 로고
    • DNA methyltransferase inhibitors: Old and new drugs for an epigenetic cancer therapy
    • Brueckner B, Lyko F. DNA methyltransferase inhibitors: old and new drugs for an epigenetic cancer therapy. Trends Pharmacol Sci 2004; 25: 551-4.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 551-554
    • Brueckner, B.1    Lyko, F.2
  • 22
    • 0027535235 scopus 로고
    • Effects of DNA methylation on DNA-binding proteins and gene expression
    • Tate PH, Bird AP. Effects of DNA methylation on DNA-binding proteins and gene expression. Curr Opin Genet Dev 1993; 3: 226-31.
    • (1993) Curr Opin Genet Dev , vol.3 , pp. 226-231
    • Tate, P.H.1    Bird, A.P.2
  • 23
    • 0037068385 scopus 로고    scopus 로고
    • Methyl-CpG binding proteins and cancer: Are MeCpGs more important than MBDs?
    • Prokhortchouk E, Hendrich B. Methyl-CpG binding proteins and cancer: are MeCpGs more important than MBDs? Oncogene 2002; 21: 5394-9.
    • (2002) Oncogene , vol.21 , pp. 5394-5399
    • Prokhortchouk, E.1    Hendrich, B.2
  • 25
    • 14544308853 scopus 로고    scopus 로고
    • Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes
    • Mohrmann L, Verrijzer CP. Composition and functional specificity of SWI2/ SNF2 class chromatin remodeling complexes. Biochim Biophys Acta 2005; 1681: 59-73.
    • (2005) Biochim Biophys Acta , vol.1681 , pp. 59-73
    • Mohrmann, L.1    Verrijzer, C.P.2
  • 26
    • 20144379888 scopus 로고    scopus 로고
    • Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing
    • Harikrishnan KN, Chow MZ, Baker EK, et al. Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing. Nat Genet 2005; 37: 254-64.
    • (2005) Nat Genet , vol.37 , pp. 254-264
    • Harikrishnan, K.N.1    Chow, M.Z.2    Baker, E.K.3
  • 27
    • 9544220768 scopus 로고    scopus 로고
    • The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein
    • Borrow J, Stanton VP Jr, Andresen JM, et al. The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Nat Genet 1996; 14: 33-41.
    • (1996) Nat Genet , vol.14 , pp. 33-41
    • Borrow, J.1    Stanton Jr., V.P.2    Andresen, J.M.3
  • 28
    • 17344366875 scopus 로고    scopus 로고
    • Detection of CBP rearrangements in acute myelogenous leukemia with t(8; 16)
    • Giles RH, Dauwerse JG, Higgins C, et al. Detection of CBP rearrangements in acute myelogenous leukemia with t(8;16). Leukemia 1997; 11: 2087-96.
    • (1997) Leukemia , vol.11 , pp. 2087-2096
    • Giles, R.H.1    Dauwerse, J.G.2    Higgins, C.3
  • 29
    • 0029940574 scopus 로고    scopus 로고
    • P300 gene alterations in colorectal and gastric carcinomas
    • Muraoka M, Konishi M, Kikuchi-Yanoshita R, et al. p300 gene alterations in colorectal and gastric carcinomas. Oncogene 1996; 12: 1565-9.
    • (1996) Oncogene , vol.12 , pp. 1565-1569
    • Muraoka, M.1    Konishi, M.2    Kikuchi-Yanoshita, R.3
  • 31
    • 17644445419 scopus 로고    scopus 로고
    • Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300
    • Yao TP, Oh SP, Fuchs M, et al. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell 1998; 93: 361-72.
    • (1998) Cell , vol.93 , pp. 361-372
    • Yao, T.P.1    Oh, S.P.2    Fuchs, M.3
  • 32
    • 0033533720 scopus 로고    scopus 로고
    • Function for p300 and not CBP in the apoptotic response to DNA damage
    • Yuan ZM, Huang Y, Ishiko T, et al. Function for p300 and not CBP in the apoptotic response to DNA damage. Oncogene 1999; 18: 5714-7.
    • (1999) Oncogene , vol.18 , pp. 5714-5717
    • Yuan, Z.M.1    Huang, Y.2    Ishiko, T.3
  • 33
    • 0036829085 scopus 로고    scopus 로고
    • Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes
    • Bandyopadhyay D, Okan NA, Bales E, Nascimento L, Cole PA, Medrano EE. Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes. Cancer Res 2002; 62: 6231-9.
    • (2002) Cancer Res , vol.62 , pp. 6231-6239
    • Bandyopadhyay, D.1    Okan, N.A.2    Bales, E.3    Nascimento, L.4    Cole, P.A.5    Medrano, E.E.6
  • 34
    • 0035962636 scopus 로고    scopus 로고
    • Transcription therapy for cancer
    • Pandolfi PP. Transcription therapy for cancer. Oncogene 2001; 20: 3116-27.
    • (2001) Oncogene , vol.20 , pp. 3116-3127
    • Pandolfi, P.P.1
  • 35
    • 0032531688 scopus 로고    scopus 로고
    • The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression
    • Dhordain P, Lin RJ, Quief S, et al. The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression. Nucleic Acids Res 1998; 26: 4645-51.
    • (1998) Nucleic Acids Res , vol.26 , pp. 4645-4651
    • Dhordain, P.1    Lin, R.J.2    Quief, S.3
  • 36
    • 0033564130 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylase relieve ETO-mediated repression and induce differentiation of AML1-ETO leukemia cells
    • Wang J, Saunthararajah Y, Redner RL, Liu JM. Inhibitors of histone deacetylase relieve ETO-mediated repression and induce differentiation of AML1-ETO leukemia cells. Cancer Res 1999; 59: 2766-9.
    • (1999) Cancer Res , vol.59 , pp. 2766-2769
    • Wang, J.1    Saunthararajah, Y.2    Redner, R.L.3    Liu, J.M.4
  • 37
    • 17944380227 scopus 로고    scopus 로고
    • Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
    • Peters AH, O'Carroll D, Scherthan H, et al. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 2001; 107: 323-37.
    • (2001) Cell , vol.107 , pp. 323-337
    • Peters, A.H.1    O'Carroll, D.2    Scherthan, H.3
  • 38
    • 0035797384 scopus 로고    scopus 로고
    • Rb targets histone H3 methylation and HP1 to promoters
    • Nielsen SJ, Schneider R, Bauer UM, et al. Rb targets histone H3 methylation and HP1 to promoters. Nature 2001; 412: 561-5.
    • (2001) Nature , vol.412 , pp. 561-565
    • Nielsen, S.J.1    Schneider, R.2    Bauer, U.M.3
  • 40
    • 0345275880 scopus 로고    scopus 로고
    • Inactivation of a histone methyltransferase by mutations in human cancers
    • Kim KC, Geng L, Huang S. Inactivation of a histone methyltransferase by mutations in human cancers. Cancer Res 2003; 63: 7619-23.
    • (2003) Cancer Res , vol.63 , pp. 7619-7623
    • Kim, K.C.1    Geng, L.2    Huang, S.3
  • 41
    • 16544395591 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • Das PM, Singal R. DNA methylation and cancer. J Clin Oncol 2004; 22: 4632-42.
    • (2004) J Clin Oncol , vol.22 , pp. 4632-4642
    • Das, P.M.1    Singal, R.2
  • 42
    • 25144523351 scopus 로고    scopus 로고
    • Biallelic methylation and silencing of paternally expressed gene 3 (PEG3) in gynecologic cancer cell lines
    • Dowdy SC, Gostout BS, Shridhar V, et al. Biallelic methylation and silencing of paternally expressed gene 3 (PEG3) in gynecologic cancer cell lines. Gynecol Oncol 2005;
    • (2005) Gynecol Oncol
    • Dowdy, S.C.1    Gostout, B.S.2    Shridhar, V.3
  • 43
    • 23444447622 scopus 로고    scopus 로고
    • Promoter methylation of p16(INK4a), RASSF1A, and DAPK is frequent in salivary adenoid cystic carcinoma
    • Li J, El-Naggar A, Mao L. Promoter methylation of p16(INK4a), RASSF1A, and DAPK is frequent in salivary adenoid cystic carcinoma. Cancer 2005; 104: 771-6.
    • (2005) Cancer , vol.104 , pp. 771-776
    • Li, J.1    El-Naggar, A.2    Mao, L.3
  • 44
    • 27744570398 scopus 로고    scopus 로고
    • Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy
    • Frigola J, Munoz M, Clark SJ, Moreno V, Capella G, Peinado MA. Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy. Oncogene 2005;
    • (2005) Oncogene
    • Frigola, J.1    Munoz, M.2    Clark, S.J.3    Moreno, V.4    Capella, G.5    Peinado, M.A.6
  • 45
    • 0033081639 scopus 로고    scopus 로고
    • Frequent hypomethylation in Wilms tumors of pericentromeric DNA in chromosomes 1 and 16
    • Qu GZ, Grundy PE, Narayan A, Ehrlich M. Frequent hypomethylation in Wilms tumors of pericentromeric DNA in chromosomes 1 and 16. Cancer Genet Cytogenet 1999; 109: 34-9.
    • (1999) Cancer Genet Cytogenet , vol.109 , pp. 34-39
    • Qu, G.Z.1    Grundy, P.E.2    Narayan, A.3    Ehrlich, M.4
  • 46
    • 0031816567 scopus 로고    scopus 로고
    • Hypomethylation of pericentromeric DNA in breast adenocarcinomas
    • Narayan A, Ji W, Zhang XY, et al. Hypomethylation of pericentromeric DNA in breast adenocarcinomas. Int J Cancer 1998; 77: 833-8.
    • (1998) Int J Cancer , vol.77 , pp. 833-838
    • Narayan, A.1    Ji, W.2    Zhang, X.Y.3
  • 47
    • 0001992028 scopus 로고    scopus 로고
    • Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential
    • Qu G, Dubeau L, Narayan A, Yu MC, Ehrlich M. Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential. Mutat Res 1999; 423: 91-101.
    • (1999) Mutat Res , vol.423 , pp. 91-101
    • Qu, G.1    Dubeau, L.2    Narayan, A.3    Yu, M.C.4    Ehrlich, M.5
  • 48
    • 3042822370 scopus 로고    scopus 로고
    • DNA hypomethylation and ovarian cancer biology
    • Widschwendter M, Jiang G, Woods C, et al. DNA hypomethylation and ovarian cancer biology. Cancer Res 2004; 64: 4472-80.
    • (2004) Cancer Res , vol.64 , pp. 4472-4480
    • Widschwendter, M.1    Jiang, G.2    Woods, C.3
  • 49
    • 0034880162 scopus 로고    scopus 로고
    • Hypomethylation of chromosome 1 heterochromatin DNA correlates with q-arm copy gain in human hepatocellular carcinoma
    • Wong N, Lam WC, Lai PB, Pang E, Lau WY, Johnson PJ. Hypomethylation of chromosome 1 heterochromatin DNA correlates with q-arm copy gain in human hepatocellular carcinoma. Am J Pathol 2001; 159: 465-71.
    • (2001) Am J Pathol , vol.159 , pp. 465-471
    • Wong, N.1    Lam, W.C.2    Lai, P.B.3    Pang, E.4    Lau, W.Y.5    Johnson, P.J.6
  • 50
    • 24744471011 scopus 로고    scopus 로고
    • Causes and consequences of DNA hypomethylation in human cancer
    • Hoffmann MJ, Schulz WA. Causes and consequences of DNA hypomethylation in human cancer. Biochem Cell Biol 2005; 83: 296-321.
    • (2005) Biochem Cell Biol , vol.83 , pp. 296-321
    • Hoffmann, M.J.1    Schulz, W.A.2
  • 51
    • 2942596268 scopus 로고    scopus 로고
    • L1 and HERV-W retrotransposons are hypomethylated in human ovarian carcinomas
    • Menendez L, Benigno BB, McDonald JF. L1 and HERV-W retrotransposons are hypomethylated in human ovarian carcinomas. Mol Cancer 2004; 3: 12.
    • (2004) Mol Cancer , vol.3 , pp. 12
    • Menendez, L.1    Benigno, B.B.2    McDonald, J.F.3
  • 52
    • 0033135573 scopus 로고    scopus 로고
    • High frequency of alterations in DNA methylation in adenocarcinoma of the prostate
    • Santourlidis S, Florl A, Ackermann R, Wirtz HC, and Schulz WA. High frequency of alterations in DNA methylation in adenocarcinoma of the prostate. Prostate 1999; 39: 166-74.
    • (1999) Prostate , vol.39 , pp. 166-174
    • Santourlidis, S.1    Florl, A.2    Ackermann, R.3    Wirtz, H.C.4    Schulz, W.A.5
  • 53
    • 0027493251 scopus 로고
    • BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription
    • Khavari PA, Peterson CL, Tamkun JW, Mendel DB, Crabtree GR. BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature 1993; 366: 170-4.
    • (1993) Nature , vol.366 , pp. 170-174
    • Khavari, P.A.1    Peterson, C.L.2    Tamkun, J.W.3    Mendel, D.B.4    Crabtree, G.R.5
  • 54
    • 0032403109 scopus 로고    scopus 로고
    • Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha)
    • Reyes JC, Barra J, Muchardt C, Camus A, Babinet C, Yaniv M. Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha). EMBO J 1998; 17: 6979-91.
    • (1998) EMBO J , vol.17 , pp. 6979-6991
    • Reyes, J.C.1    Barra, J.2    Muchardt, C.3    Camus, A.4    Babinet, C.5    Yaniv, M.6
  • 57
    • 2642647094 scopus 로고    scopus 로고
    • Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
    • Versteege I, Sevenet N, Lange J, et al. Truncating mutations of hSNF5/ INI1 in aggressive paediatric cancer. Nature 1998; 394: 203-6.
    • (1998) Nature , vol.394 , pp. 203-206
    • Versteege, I.1    Sevenet, N.2    Lange, J.3
  • 58
    • 0942287188 scopus 로고    scopus 로고
    • P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells
    • Oruetxebarria I, Venturini F, Kekarainen T, et al. P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells. J Biol Chem 2004; 279: 3807-16.
    • (2004) J Biol Chem , vol.279 , pp. 3807-3816
    • Oruetxebarria, I.1    Venturini, F.2    Kekarainen, T.3
  • 59
    • 0034973588 scopus 로고    scopus 로고
    • Essential roles of Snf5p in Snf-Swi chromatin remodeling in vivo
    • Geng F, Cao Y, Laurent BC. Essential roles of Snf5p in Snf-Swi chromatin remodeling in vivo. Mol Cell Biol 2001; 21: 4311-20.
    • (2001) Mol Cell Biol , vol.21 , pp. 4311-4320
    • Geng, F.1    Cao, Y.2    Laurent, B.C.3
  • 60
    • 0028566214 scopus 로고
    • Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5
    • Kalpana GV, Marmon S, Wang W, Crabtree GR, Goff SP. Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5. Science 1994; 266: 2002-6.
    • (1994) Science , vol.266 , pp. 2002-2006
    • Kalpana, G.V.1    Marmon, S.2    Wang, W.3    Crabtree, G.R.4    Goff, S.P.5
  • 61
    • 0034326257 scopus 로고    scopus 로고
    • BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines
    • Wong AK, Shanahan F, Chen Y, et al. BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res 2000; 60: 6171-7.
    • (2000) Cancer Res , vol.60 , pp. 6171-6177
    • Wong, A.K.1    Shanahan, F.2    Chen, Y.3
  • 62
    • 16344391638 scopus 로고    scopus 로고
    • In vitro study of CI-994, a histone deacetylase inhibitor, in non-small cell lung cancer cell lines
    • Loprevite M, Tiseo M, Grossi F, et al. In vitro study of CI-994, a histone deacetylase inhibitor, in non-small cell lung cancer cell lines. Oncol Res 2005; 15: 39-48.
    • (2005) Oncol Res , vol.15 , pp. 39-48
    • Loprevite, M.1    Tiseo, M.2    Grossi, F.3
  • 63
    • 0033551152 scopus 로고    scopus 로고
    • A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors
    • Saito A, Yamashita T, Mariko Y. et al. A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors. Proc Natl Acad Sci USA 1999; 96: 4592-7.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 4592-4597
    • Saito, A.1    Yamashita, T.2    Mariko, Y.3
  • 64
    • 1642453460 scopus 로고    scopus 로고
    • Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101
    • Plumb JA, Finn PW, Williams RJ, et al. Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101. Mol Cancer Ther 2003; 2: 721-8.
    • (2003) Mol Cancer Ther , vol.2 , pp. 721-728
    • Plumb, J.A.1    Finn, P.W.2    Williams, R.J.3
  • 65
    • 11844278521 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors
    • Monneret C. Histone deacetylase inhibitors. Eur J Med Chem 2005; 40: 1-13.
    • (2005) Eur J Med Chem , vol.40 , pp. 1-13
    • Monneret, C.1
  • 66
    • 0033562343 scopus 로고    scopus 로고
    • Both Sp1 and Sp3 are responsible for p21waf1 promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells
    • Xiao H, Hasegawa T, Isobe K. Both Sp1 and Sp3 are responsible for p21waf1 promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells. J Cell Biochem 1999; 73: 291-302.
    • (1999) J Cell Biochem , vol.73 , pp. 291-302
    • Xiao, H.1    Hasegawa, T.2    Isobe, K.3
  • 67
    • 10044225745 scopus 로고    scopus 로고
    • Human ovarian carcinoma cells: Histone deacetylase inhibitors exhibit antiproliferative activity and potently induce apoptosis
    • Takai N, Kawamata N, Gui D, Said JW, Miyakawa I, Koeffler HP. Human ovarian carcinoma cells: histone deacetylase inhibitors exhibit antiproliferative activity and potently induce apoptosis. Cancer 2004; 101: 2760-70.
    • (2004) Cancer , vol.101 , pp. 2760-2770
    • Takai, N.1    Kawamata, N.2    Gui, D.3    Said, J.W.4    Miyakawa, I.5    Koeffler, H.P.6
  • 68
    • 16844362441 scopus 로고    scopus 로고
    • Histone deacetylation in epigenetics: An attractive target for anticancer therapy
    • Mai A, Massa S, Rotili D, et al. Histone deacetylation in epigenetics: an attractive target for anticancer therapy. Med Res Rev 2005; 25: 261-309.
    • (2005) Med Res Rev , vol.25 , pp. 261-309
    • Mai, A.1    Massa, S.2    Rotili, D.3
  • 69
    • 7444256739 scopus 로고    scopus 로고
    • Overexpression of histone deacetylase 1 confers resistance to sodium butyrate-mediated apoptosis in melanoma cells through a p53-mediated pathway
    • Bandyopadhyay D, Mishra A, Medrano EE. Overexpression of histone deacetylase 1 confers resistance to sodium butyrate-mediated apoptosis in melanoma cells through a p53-mediated pathway. Cancer Res 2004; 64: 7706-10.
    • (2004) Cancer Res , vol.64 , pp. 7706-7710
    • Bandyopadhyay, D.1    Mishra, A.2    Medrano, E.E.3
  • 70
    • 0042905956 scopus 로고    scopus 로고
    • Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: Defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines
    • Glaser KB, Staver MJ, Waring JF, Stender J, Ulrich RG, Davidsen SK. Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines. Mol Cancer Ther 2003; 2: 151-63.
    • (2003) Mol Cancer Ther , vol.2 , pp. 151-163
    • Glaser, K.B.1    Staver, M.J.2    Waring, J.F.3    Stender, J.4    Ulrich, R.G.5    Davidsen, S.K.6
  • 72
    • 4644364508 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor NVP-LAQ824 inhibits angiogenesis and has a greater antitumor effect in combination with the vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584
    • Qian DZ, Wang X, Kachhap SK, et al. The histone deacetylase inhibitor NVP-LAQ824 inhibits angiogenesis and has a greater antitumor effect in combination with the vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584. Cancer Res 2004; 64: 6626-34.
    • (2004) Cancer Res , vol.64 , pp. 6626-6634
    • Qian, D.Z.1    Wang, X.2    Kachhap, S.K.3
  • 73
    • 0038408486 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion
    • Liu LT, Chang HC, Chiang LC, Hung WC. Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion. Cancer Res 2003; 63: 3069-72.
    • (2003) Cancer Res , vol.63 , pp. 3069-3072
    • Liu, L.T.1    Chang, H.C.2    Chiang, L.C.3    Hung, W.C.4
  • 74
    • 0035823497 scopus 로고    scopus 로고
    • Transcriptional coactivator protein p300. Kinetic characterization of its histone acetyltransferase activity
    • Thompson PR, Kurooka H, Nakatani Y, Cole PA. Transcriptional coactivator protein p300. Kinetic characterization of its histone acetyltransferase activity. J Biol Chem 2001; 276: 33721-9.
    • (2001) J Biol Chem , vol.276 , pp. 33721-33729
    • Thompson, P.R.1    Kurooka, H.2    Nakatani, Y.3    Cole, P.A.4
  • 75
    • 10944243759 scopus 로고    scopus 로고
    • Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
    • Balasubramanyam K, Varier RA, Altaf M, et al. Curcumin, a novel p300/ CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. J Biol Chem 2004; 279: 51163-71.
    • (2004) J Biol Chem , vol.279 , pp. 51163-51171
    • Balasubramanyam, K.1    Varier, R.A.2    Altaf, M.3
  • 76
    • 19944433949 scopus 로고    scopus 로고
    • The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin
    • Davidson SM, Townsend PA, Carroll C, et al. The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin. Chembiochem 2005; 6: 162-70.
    • (2005) Chembiochem , vol.6 , pp. 162-170
    • Davidson, S.M.1    Townsend, P.A.2    Carroll, C.3
  • 77
    • 0038079767 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1
    • Rosato RR, Almenara JA, Grant S. The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1. Cancer Res 2003; 63: 3637-45.
    • (2003) Cancer Res , vol.63 , pp. 3637-3645
    • Rosato, R.R.1    Almenara, J.A.2    Grant, S.3
  • 78
    • 0034665124 scopus 로고    scopus 로고
    • Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo
    • Butler LM, Agus DB, Scher HI, et al. Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo. Cancer Res 2000; 60: 5165-70.
    • (2000) Cancer Res , vol.60 , pp. 5165-5170
    • Butler, L.M.1    Agus, D.B.2    Scher, H.I.3
  • 79
    • 0041347519 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer therapy: Is transcription the primary target?
    • Johnstone RW, Licht JD. Histone deacetylase inhibitors in cancer therapy: is transcription the primary target? Cancer Cell 2003; 4: 13-8.
    • (2003) Cancer Cell , vol.4 , pp. 13-18
    • Johnstone, R.W.1    Licht, J.D.2
  • 80
    • 0034596309 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Inducers of differentiation or apoptosis of transformed cells
    • Marks PA, Richon VM, Rifkind RA. Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells. J Natl Cancer Inst 2000; 92: 1210-6.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1210-1216
    • Marks, P.A.1    Richon, V.M.2    Rifkind, R.A.3
  • 81
    • 20044390016 scopus 로고    scopus 로고
    • Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors
    • Ungerstedt JS, Sowa Y, Xu WS, et al. Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors. Proc Natl Acad Sci USA 2005; 102: 673-8.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 673-678
    • Ungerstedt, J.S.1    Sowa, Y.2    Xu, W.S.3
  • 82
    • 13444274622 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
    • Insinga A, Monestiroli S, Ronzoni S, et al. Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway. Nat Med 2005; 11: 71-6.
    • (2005) Nat Med , vol.11 , pp. 71-76
    • Insinga, A.1    Monestiroli, S.2    Ronzoni, S.3
  • 83
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger G, Liang G, Aparicio A, Jones PA. Epigenetics in human disease and prospects for epigenetic therapy. Nature 2004; 429: 457-63.
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 84
    • 10744233452 scopus 로고    scopus 로고
    • Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in hematopoietic malignancies
    • Issa JP, Garcia-Manero G, Giles FJ, et al. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in hematopoietic malignancies. Blood 2004; 103: 1635-40.
    • (2004) Blood , vol.103 , pp. 1635-1640
    • Issa, J.P.1    Garcia-Manero, G.2    Giles, F.J.3
  • 85
    • 0037420191 scopus 로고    scopus 로고
    • Inhibition of DNA methylation and reactivation of silenced genes by zebularine
    • Cheng JC, Matsen CB, Gonzales FA, et al. Inhibition of DNA methylation and reactivation of silenced genes by zebularine. J Natl Cancer Inst 2003; 95: 399-409.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 399-409
    • Cheng, J.C.1    Matsen, C.B.2    Gonzales, F.A.3
  • 86
    • 0041939756 scopus 로고    scopus 로고
    • Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells
    • Villar-Garea A, Fraga MF, Espada J, Esteller M. Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res 2003; 63: 4984-9.
    • (2003) Cancer Res , vol.63 , pp. 4984-4989
    • Villar-Garea, A.1    Fraga, M.F.2    Espada, J.3    Esteller, M.4
  • 87
    • 0345275879 scopus 로고    scopus 로고
    • Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
    • Fang MZ, Wang Y, Ai N, et al. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 2003; 63: 7563-70.
    • (2003) Cancer Res , vol.63 , pp. 7563-7570
    • Fang, M.Z.1    Wang, Y.2    Ai, N.3
  • 88
    • 1542787625 scopus 로고    scopus 로고
    • Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines
    • Yan L, Nass SJ, Smith D, Nelson WG, Herman JG, Davidson NE. Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines. Cancer Biol Ther 2003; 2: 552-6.
    • (2003) Cancer Biol Ther , vol.2 , pp. 552-556
    • Yan, L.1    Nass, S.J.2    Smith, D.3    Nelson, W.G.4    Herman, J.G.5    Davidson, N.E.6
  • 89
    • 0035866353 scopus 로고    scopus 로고
    • DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors
    • Zhu WG, Lakshmanan RR, Beal MD, Otterson GA. DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors. Cancer Res 2001; 61: 1327-33.
    • (2001) Cancer Res , vol.61 , pp. 1327-1333
    • Zhu, W.G.1    Lakshmanan, R.R.2    Beal, M.D.3    Otterson, G.A.4
  • 90
    • 0242442588 scopus 로고    scopus 로고
    • Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer
    • Belinsky SA, Klinge DM, Stidley CA, et al. Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer. Cancer Res 2003; 63: 7089-93.
    • (2003) Cancer Res , vol.63 , pp. 7089-7093
    • Belinsky, S.A.1    Klinge, D.M.2    Stidley, C.A.3
  • 91
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and historic deacetylase inhibition in the re-expression of genes silenced in cancer
    • Cameron EE, Bachman KE, Myohanen S. Herman JG, Baylin SB. Synergy of demethylation and historic deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 1999; 21: 103-7.
    • (1999) Nat Genet , vol.21 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3    Herman, J.G.4    Baylin, S.B.5
  • 92
    • 0037427805 scopus 로고    scopus 로고
    • Synergistic antineoplastic action of DNA methylation inhibitor 5-AZA-2′-deoxycytidine and histone deacetylase inhibitor depsipeptide on human breast carcinoma cells
    • Primeau M, Gagnon J, Momparler RL. Synergistic antineoplastic action of DNA methylation inhibitor 5-AZA-2′-deoxycytidine and histone deacetylase inhibitor depsipeptide on human breast carcinoma cells. Int J Cancer 2003; 103: 177-84.
    • (2003) Int J Cancer , vol.103 , pp. 177-184
    • Primeau, M.1    Gagnon, J.2    Momparler, R.L.3
  • 93
    • 30044436031 scopus 로고    scopus 로고
    • Flavopiridol and histone deacetylase inhibitors promote mitochondrial injury and cell death in human leukemia cells overexpressing BCL-2
    • Dasmahapatra G, Almenara J, Grant S. Flavopiridol and histone deacetylase inhibitors promote mitochondrial injury and cell death in human leukemia cells overexpressing BCL-2. Mol Pharmacol 2006; 69: 288-98.
    • (2006) Mol Pharmacol , vol.69 , pp. 288-298
    • Dasmahapatra, G.1    Almenara, J.2    Grant, S.3
  • 94
    • 1342308338 scopus 로고    scopus 로고
    • Evidence of a functional role for p21WAF1/CIP1 down-regulation in synergistic antileukemic interactions between the histone deacetylase inhibitor sodium butyrate and flavopiridol
    • Rosato RR, Almenara JA, Yu C, Grant S. Evidence of a functional role for p21WAF1/CIP1 down-regulation in synergistic antileukemic interactions between the histone deacetylase inhibitor sodium butyrate and flavopiridol. Mol Pharmacol 2004; 65: 571-81.
    • (2004) Mol Pharmacol , vol.65 , pp. 571-581
    • Rosato, R.R.1    Almenara, J.A.2    Yu, C.3    Grant, S.4
  • 95
    • 1642555570 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in clinical development
    • Rosato RR, Grant S. Histone deacetylase inhibitors in clinical development. Expert Opin Investig Drugs 2004; 13: 21-38.
    • (2004) Expert Opin Investig Drugs , vol.13 , pp. 21-38
    • Rosato, R.R.1    Grant, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.