Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor α (ER) in ER-negative human breast cancer cell lines

Cancer Biology and Therapy

Volumn 2, Issue 5, 2003, Pages 552-556

  Yan, Lan ^a,b   Nass, Sharyl J ^a,c   Smith, Dawn ^a,d   Nelson, William G ^a   Herman, James G ^a   Davidson, Nancy E ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b PFIZER INC   (United States)

^c NATIONAL ACADEMIES OF SCIENCES   (United States)

^d CENTOCOR INC   (United States)

Author keywords

Antisense oligonucleotide; Breast cancer; DNA methylation; DNA methyltransferase 1; Estrogen receptor

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ANTISENSE OLIGONUCLEOTIDE; AZACITIDINE; DNA (CYTOSINE 5 ) METHYLTRANSFERASE 1; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; DRUG DERIVATIVE; ENZYME INHIBITOR; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; LUCIFERASE; MESSENGER RNA;

ARTICLE; BREAST TUMOR; CELL CULTURE; CPG ISLAND; DNA METHYLATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AZACITIDINE; BREAST NEOPLASMS; CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; ENZYME INHIBITORS; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUCIFERASES; OLIGONUCLEOTIDES, ANTISENSE; RECEPTORS, ESTROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 1542787625     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.2.5.469     Document Type: Article

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