Both Sp1 and Sp3 are responsible for p21(waf1) promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells

Journal of Cellular Biochemistry

Volumn 73, Issue 3, 1999, Pages 291-302

  Xiao, Hengyi ^a,b   Hasegawa, Tadao ^a   Isobe, Ken Ichi ^a  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Histone acetylation; p2(WAF1); Promoter; Sp1; Sp3

Indexed keywords

HISTONE DEACETYLASE; PROTEIN P21;

ACETYLATION; ARTICLE; CELL STRAIN 3T3; DNA FLANKING REGION; ELECTROPHORETIC MOBILITY; ENZYME ACTIVITY; ENZYME INHIBITION; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; TATA BOX; TRANSCRIPTION INITIATION;

3T3 CELLS; ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; GENES, REPORTER; HISTONE DEACETYLASES; HYDROXAMIC ACIDS; LUCIFERASES; MICE; MODELS, GENETIC; MUTAGENESIS; OLIGONUCLEOTIDES, ANTISENSE; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SP1 TRANSCRIPTION FACTOR; SP3 TRANSCRIPTION FACTOR; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0033562343     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19990601)73:3<291::AID-JCB1>3.0.CO;2-5     Document Type: Article

References (35)

1. Avantaggiati ML, Ogryzko V, Gardner K, Giordano A, Levine AS, Kelly K. 1997. Recruitment of p300/CBP in p53-dependent signal pathways. Cell 89:1175-1184.
2. Biggs JR, Kudlow JE, Kraft AS. 1996. The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells. J Biol Chem 271:901-906.
3. Datto MB, Yu Y, Wang XF. 1995. Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter. J Biol Chem 270:28623-28628.
4. Dennig J, Beato M, Suske G. 1996. An inhibitor domain in Sp3 regulates its glutamine-rich activation domains. EMBO J 15:5659-5667.
5. Dulic V, Kaufmann WK, Wilson SJ, Tlsty TD, Lees E, Harper JW, Elledge SJ, Reed SI. 1994. p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76: 1013-1023.
6. El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B. 1993. WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825.
7. Garcia-Ramirez M, Rocchini C, Ausio J. 1995. Modulation of chromatin folding by histone acetylation. J Biol Chem 270:17923-17928.
8. Gu W, Roeder RG. 1997. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90:595-606.
9. Gu Y, Turck CW, Morgan DO. 1993. Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature 366:707-710.
10. Hagen G, Muller S, Beato M, Suske G. 1992. Cloning by recognition site screening of two novel GT box binding proteins: A family of Sp1 related genes. Nucleic Acids Res 20:5519-5525.
11. Hagen G, Muller S, Beato M, Suske G. 1994. Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J 13:3843-3851.
12. Hagopian HK, Riggs MG, Swartz LA, Ingram VM. 1977. Effect of n-butyrate on DNA synthesis in chick fibroblasts and HeLa cells. Cell 12:855-860.
13. Halevy O, Novitch BG, Spicer DB, Skapek SX, Rhee J, Hannon GJ, Beach D, Lassar AB. 1995. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science 267:1018-1021.
14. Hasegawa T, Takeuchi A, Miyaishi O, Isobe K, Crombrugghe B. 1997. Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes. J Biol Chem 21:4915-4923.
15. Kadonaga JT, Carner KR, Masiarz FR, Tjian R. 1987. Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell 51:1079-1090.
16. Kingsley C, Winoto A. 1992. Cloning of GT box-binding proteins: A novel Sp1 multigene family regulating T-cell receptor gene expression. Mol Cell Biol 12:4251-4261.
17. Jiang H, Lin J, Su ZZ, Herlyn M, Kerbel RS, Weissman BE, Welch DR, Fisher PB. 1995. The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells. Oncogene 10:1855-1864.
18. Lee DY, Hayes JJ, Pruss D, Wolffe AP. 1993. A positive role for histone acetylation in transcription factor access to nucleosomal DNA. Cell 72:73-84.
19. Macleod KF, Sherry N, Hannon G, Beach D, Tokino T, Kinzler K, Vogelstein B, Jacks T. 1995. p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev 9:935-944.
20. Majello B, De Luca P, Hagen G, Suske G, Lania L. 1994. Different members of the Sp1 multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1. Nucleic Acids Res 22:4914-4921.
21. Missero C, Calautti E, Eckner R, Chin J, Tsai LH, Livingston DM, Dotto GP. 1995. Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc Natl Acad Sci USA 92:5451-5455.
22. Nakano K, Mizuno T, Sowa Y, Orita T, Yoshino T, Okuyama Y, Fujita T, Ohtani-Fujita N, Matsukawa Y, Tokino T, Yamagishi H, Oka T, Nomura H, Sakai T. 1997. Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line. J Biol Chem 272:22199-22206.
23. Nielsen SJ, Prastegaard M, Jorgensen HF, Clark BF. 1998. Different Sp1 family members differentially affect transcription from the humanelongation factor 1 A-1 gene promoter. Biochem J 333:511-517.
24. Parker SB, Eichele G, Zhang P, Rawls A, Sands AT, Bradley A, Olson EN, Harper JW, Elledge SJ. 1995. p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science 267:1024-1027.
25. Parks CL, Shenk TJ. 1996. The serotonin 1a receptor gene contains a TATA-less promoter that responds to MAZ and Sp1. J Biol Chem 271:4417-4430.
26. Prasad K, Sinha P. 1976. Effect of sodium butyrate on mammalian cells in culture: A review. In Vitro 12:125-132.
27. Prowse DM, Bolgan L, Molnar A, Dotto GP. 1997. Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation. J Biol Chem 272:1308-1314.
28. Puri PL, Sartorelli V, Yang XJ, Hamamori Y, Ogryzko VV, Howard BH, Kedes L, Wang JY, Graessmann A, Nakatani Y, Levrero M. 1997. Differential roles of p300 and PCAF acetyltransferases in muscle differentiation. Mol Cell 1:35-45.
29. Schlake T, Klehr-Wirth D, Yoshida M, Beppu T, Bode J. 1994. Gene expression within a chromatin domain: The role of core histone hyperacetylation. Biochemistry 33: 4197-4206.
30. Udavadia AJ, Templeton DJ, Horowitz JM. 1995. Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: Superactivation by Rb requires amino acids necessary for growth suppression. Proc Natl Acad Sci USA 92:3953-3957.
31. Xiao H, Hasegawa T, Miyaishi O, Ohkusu K, Isobe K 1997. Sodium butyrate induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21WAF/ CIP1 in p53-independent manner. Biochem Biophys Res Commun 237:457-460.
32. Yamamoto I, Matsunaga T, Sakata K, Nakamura Y, Doi S, Hanmyou F. 1996. Histone hyperacetylation plays a role in augmentation of IL-4-induced IgE production in LPS-stimulated murine B-lymphocytes by sodium butyrate. J Biochem (Tokyo) 19:1056-1061.
33. Yan GZ, Ziff EB. 1997. Nerve growth factor induces transcription of the p21 WAF1/CIP1 and cyclin D1 genes in PC12 cells by activating the Sp1 transcription factor. J Neurosci 17:6122-6132.
34. Yang WM, Yao YL, Sun JM, Davie JR, Seto E. 1997. Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family. J Biol Chem 272:28001-28007.
35. Yoshida M, Horinouchi S, Beppu T. 1995. Trichostatin A and trapoxin: Novel chemical probes for the role of histone acetylation in chromatin structure and function. BioEssays 17:423-430.