Detection of CBP rearrangements in acute myelogenous leukemia with t(8;16)

Leukemia

Volumn 11, Issue 12, 1997, Pages 2087-2096

  Giles, R H ^a   Dauwerse, J G ^a   Higgins, C ^a   Petrij, F ^a   Wessels, J W ^a   Beverstock, G C ^a   Dohner H ^b   Jotterand Bellomo, M ^c   Falkenburg, J H F ^d   Slater, R M ^e   Van Ommen, G J B ^a   Hagemeijer, A ^f   Van Der Reijden, B A ^f   Breuning, M H ^a,g  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^e UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^f ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^g LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Acute myeloid leukemia; CREB binding protein; MOZ; t(8; 16)(p11; p13.3)

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NUCLEAR PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CHROMATIN; CHROMOSOME 16P; CHROMOSOME 8P; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CHROMOSOME MAP; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION 8; CLINICAL ARTICLE; CONTROLLED STUDY; COSMID; FLUORESCENCE IN SITU HYBRIDIZATION; GENE CLUSTER; GENE DISRUPTION; GENE FUSION; GENE LOCUS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; METAPHASE CHROMOSOME; MOLECULAR CLONING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOUTHERN BLOTTING;

EID: 17344366875     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2400882     Document Type: Article

References (11)

1. Giles RH, Petrij F, Dauwerse JG, den Hollander AI, Lushnikova T, van Ommen G-JB, Goodman RH, Deaven LL, Doggert NA, Peters DJM, Breuning MH. Construction of a 1.2-Mb contig surrounding, and molecular analysis of, the human CREB-binding protein (CBP/CREBBP) gene on chromosome 16p13.3. Genomics 1997; 42: 96-114.
2. Bannister AJ, Kouzarides T. The CBP co-activator is a histone acetyltransferase. Nature 1996; 384: 641-643.
3. Ogryzko VV, Schiltz RL, Russanova V, Howard BH, Nakatani Y. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 1996; 87: 953-959.
4. Giles RH, Petrij F, Dauwerse JG, van der Reijden BA, Beverstock GC, Hagemeijer A, Breuning MH. The translocation t(8;16) in ANLL M4/M5 disrupts the CBP gene on chromosome 16. Blood 1995;86:35a.
5. Petrij F, Giles RH, Dauwerse JG, Saris JJ, Hennekam RCM, Masuno M, Tommerup N, van Ommen GJB, Goodman RH, Peters DJM, Breuning MH. Rubinstein-Taybi syndrome is caused by mutations in the transcriptional co-activator CBP. Nature 1995; 376: 348-351.
6. Borrow J, Stanton VP Jr, Andresen JM, Becher R, Behm FG, Chaganti RSK, Civin CI, Disteche C, Dubé I, Frischauf AM, Horsman D, Mitelman F, Volinia S, Watmore AE, Housman DE. The translocation t(8;16)(p11;p13) of acute myeloid leukemia fuses a putative acetyl transferase to the CREB-binding protein. Nat Genet 1996; 14: 33-41.
7. Taki T, Sako M, Tsuchida M, Hayashi Y. The t(11;16)(q23;p13) translocation in myelodysplastic syndrome fuses the MLL gene to the CBP gene. Blood 1997; 89: 3945-3950.
8. Rowley JD, Reshmi S, Sobulo O, Musvee T, Anastasi J, Raimondi S, Schneider NR, Barredo JC, Cantu ES, Schlegelberger B, Behm F, Doggett NA, Borrow J, Zeleznik-Le N. All patients with the t(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders. Blood 1997; 90: 535-541.
9. Sobulo OM, Borrow J, Tomek R, Reshmi S, Harden A, Schlegelberger B, Housman D, Doggett NA, Rowley JD, Zeleznik-Le NJ. MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3). Proc Natl Acad Sci USA 1997; 94: 8732-8737.
10. Satake N, Ishida Y, Otoh Y, Hinohara S, Kobayashi H, Sakashita A, Maseki N, Kaneko Y. Novel MLL-CBP fusion transcript in therapyrelated chronic myelomonocytic leukemia with a t(11;16)(q23;p13). Genes Chromos Cancer 1997; 20: 60-63.
11. Hanslip JI, Swansbury GJ, Pinkerton R, Catovsky D. The translocation t(8;16)(p11;p13) defines an AML subtype with distinct cytology and clinical features. Leuk Lymphoma 1992; 6: 479-486.