S18616, a highly potent spiroimidazoline agonist at α2-adrenoceptors: II. Influence on monoaminergic transmission, motor function, and anxiety in comparison with dexmedetomidine and clonidine

Journal of Pharmacology and Experimental Therapeutics

Volumn 295, Issue 3, 2000, Pages 1206-1222

  Millan, Mark J ^a   Lejeune, Françoise ^a   Gobert, Alain ^a   Brocco, Mauricette ^a   Auclair, Agnés ^a   Bosc, Catherine ^a   Rivet, Jean Michel ^a   Lacoste, Jean Michel ^a   Cordi, Alex ^a   Dekeyne, Anne ^a  

^a INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 (1 METHYL 2 ISOINDOLINYLMETHYL) 2 IMIDAZOLINE; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ATIPAMEZOLE; CLONIDINE; DEXMEDETOMIDINE; DOPAMINE; IDAZOXAN; NORADRENALIN; PRAZOSIN; S 18616; SEROTONIN; SPIRO[(1 OXA 2 AMINO 3 AZACYCLOPENT 2 ENE) 4,2' (8' CHLORO 1',2',3',4' TETRAHYDRONAPHTHALENE)]; UNCLASSIFIED DRUG;

AGGRESSIVENESS; ANIMAL CELL; ANXIETY; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; DORSAL RAPHE NUCLEUS; DOSE RESPONSE; DRUG POTENCY; ELECTRIC ACTIVITY; FRONTAL CORTEX; HIPPOCAMPUS; LOCUS CERULEUS; MALE; MONOAMINERGIC SYSTEM; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONINERGIC NERVE CELL; SOCIAL INTERACTION; TRANQUILIZING ACTIVITY;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; ANTI-ANXIETY AGENTS; BIOGENIC MONOAMINES; CLONIDINE; DEXMEDETOMIDINE; IMIDAZOLES; LOCUS COERULEUS; MALE; MICE; MOTOR ACTIVITY; OXAZOLES; RAPHE NUCLEI; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-2; VENTRAL TEGMENTAL AREA; VOCALIZATION, ANIMAL;

EID: 0033695376     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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