Effects of aryl hydrocarbon receptor null mutation and in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on prostate and seminal vesicle development in C57BL/6 mice

Toxicological Sciences

Volumn 68, Issue 2, 2002, Pages 479-487

  Lin, Tien Min ^a   Ko, Kinarm ^a   Moore, Robert W ^a   Simanainen, Ulla ^a,d   Oberley, Terry D ^a,b,c   Peterson, Richard E ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

2,3,7,8 tetrachlorodibenzo p dioxin; AhRKO mice; Aryl hydrocarbon receptor null mutation; Development; Gene expression; In utero; Lactational exposure; Mice; Prostate; Seminal vesicles; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANEDIOL; AROMATIC HYDROCARBON RECEPTOR; BETA MICROSEMINOPROTEIN; MESSENGER RNA; PROBASIN; PROSTATE PROTEIN; RENIN; SECRETORY PROTEIN; TESTOSTERONE; ANDROGEN BINDING PROTEIN; PRIMER DNA;

ANDROGEN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; BREEDING; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GESTATIONAL AGE; GONAD DEVELOPMENT; HETEROZYGOSITY; HISTOPATHOLOGY; KNOCKOUT MOUSE; LACTATION; MALE; MOUSE STRAIN; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PRENATAL EXPOSURE; PROSTATE; SEMINAL VESICLE; SIGNAL TRANSDUCTION; TESTOSTERONE BLOOD LEVEL; TOXICITY TESTING; WILD TYPE; ANIMAL; C57BL MOUSE; CHEMISTRY; CONGENITAL MALFORMATION; DRUG EFFECT; ENVIRONMENTAL EXPOSURE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE; MOUSE MUTANT; NEWBORN; ORAL DRUG ADMINISTRATION; ORGAN SIZE; ORGANOGENESIS; POLLUTANT; PREGNANCY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADMINISTRATION, ORAL; ANDROGEN-BINDING PROTEIN; ANIMAL; ANIMALS, NEWBORN; DNA PRIMERS; ENVIRONMENTAL POLLUTANTS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LACTATION; MALE; MATERNAL EXPOSURE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORGAN WEIGHT; ORGANOGENESIS; PREGNANCY; PROSTATE; RECEPTORS, ARYL HYDROCARBON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEMINAL VESICLES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TETRACHLORODIBENZODIOXIN; ANIMALS; ORGAN SIZE;

ANIMALIA;

EID: 0036667370     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/68.2.479     Document Type: Article

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