In utero and lactational exposure of the male rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs prostate development. 1. Effects on gene expression

Toxicology and Applied Pharmacology

Volumn 150, Issue 2, 1998, Pages 240-253

  Roman, Beth L ^a   Peterson, Richard E ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ANDROGEN; AROMATIC HYDROCARBON RECEPTOR; BINDING PROTEIN; CARRIER PROTEIN; ETHOXYRESORUFIN DEETHYLASE; MESSENGER RNA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; ORGAN WEIGHT; PERINATAL DRUG EXPOSURE; POSTNATAL DEVELOPMENT; PRENATAL DEVELOPMENT; PRENATAL EXPOSURE; PROSTATE; PROSTATE EPITHELIUM; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS;

ANIMALIA;

EID: 0032104188     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1997.8362     Document Type: Article

References (57)

1. Bjerke D. L., Sommer R. J., Moore R. W., Peterson R. E. Effects ofin uterop. Toxicol. Appl. Pharmacol. 127:1994;250-257.
2. Carmo-Fonesca M., Vaz Y. Immunocytochemical localization and lectin binding properties of the 22 kDa secretory protein from rat ventral prostate. Biol. Reprod. 40:1989;153-164.
3. Carver L. A., Hogenesch J. B., Bradfield C. A. Tissue specific expression of the rat Ah-receptor and ARNT mRNAs. Nucleic Acids Res. 22:1994;3038-3044.
4. Chamberlin L. L., Mpanias O. D., Wang T. Y. Isolation properties and androgen regulation of a 20-kilodalton protein from rat ventral prostate. Biochemistry. 22:1983;3072-3077.
5. Chang S., Saltzman A., Yeh S., Young W., Keller E., Lee H.-J., Wang C., Mizokami A. Androgen receptor: An overview. Crit. Rev. Euk. Gene Express. 5:1995;97-125.
6. Chen S.-W., Roman B. L, Saroya S. Z., Shinomiya K., Moore R. W., Peterson R. E. In uterop. Toxicologist. 13:1993.
7. Choi E. J., Toscano D. G., Ryan J. A., Riedel N., Toscano W. A. Jr. Dioxin induces transforming growth factor-α in human keratinocytes. J. Biol. Chem. 266:1991;9591-9597.
8. Claessens F., Celis L., De Vos P., Peeters B., Heyns W., Verhoeven G., Rombauts W. Intronic androgen response elements of prostatic binding protein genes. Biochem. Biophys. Res. Commun. 191:1993;688-694.
9. Dodd J. G., Sheppard P. C., Matusik R.J. Characterization and cloning of rat dorsolateral prostate mRNAs. J. Biol. Chem. 258:1983;10731-10737.
10. Dolwick K. M., Swanson H. I., Bradfield C. A. In vitro. Proc. Natl. Acad. Sci. USA. 90:1993;8566-8570.
11. Fernandez-Salguero P. M., Hilbert D. M., Rudikoff S., Ward J. M., Gonzalez F. J. Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p. Toxicol. Appl. Pharmacol. 140:1996;173-179.
12. Flickinger C. J. The fine structure and development of the seminal vesicles and prostate in the fetal rat. Z. Zellforsch. Mikrosk. Anat. 109:1970;1-14.
13. Forsgren B., Björk P., Carlström K., Gustafsson J.-Å., Pousette Å., Högberg B. Purification and distribution of a major protein in rat prostate that binds estramustine, a nitrogen mustard derivative of estradiol-17β Proc. Natl. Acad. Sci. USA. 76:1979;3149-3153.
14. Furuhashi N., Kurl R. N., Wong J., Villee C. A. A cytosolic binding protein for 2,3,7,8-tetrachlorodibenzo-p. Pharmacology. 33:1986;110-120.
15. Gaido K. W., Maness S. C. Regulation of gene expression and acceleration of differentiation in human keratinocytes by 2,3,7,8-tetrachlorodibenzo-p. Toxicol. Appl. Pharmacol. 127:1994;199-208.
16. 2. J. Biol. Chem. 267:1992;24591-24595.
17. Haaparanta T., Glaumann H., Gustaffson J.-Å. Induction of cytochrome P-450 dependent reactions in the rat ventral prostate by β-naphthoflavone and 2,3,7,8-tetrachlorodibenzo-p. Toxicology. 29:1983;61-75.
18. Heyns W., Van Damme B., De Moor P. Secretion of prostatic binding protein by rat ventral prostate: Influence of age and androgen. Endocrinology. 103:1978;1090-1095.
19. Ho K.-C., Marschke K. B., Tan J., Power S. G. A., Wilson E. M., French F. S. A complex response element in intron 1 of the androgen-regulated 20-kDa protein gene displays cell type-dependent androgen receptor specificity. J. Biol. Chem. 268:1993;27226-27235.
20. Ho K.-C., Quarmby V. E., French F. S., Wilson E. M. Molecular cloning of rat prostate transglutaminase complementary cDNA. J. Biol. Chem. 267:1992;12660-12667.
21. Ho K.-C., Snoek R., Quarmby V., Viskochil D. H., Rennie P. S., Wilson E. M., French F. S., Bruchovsky N. Primary structure and androgen regulation of a 20-kilodalton protein specific to rat ventral prostate. Biochemistry. 28:1989;6367-6373.
22. Katzenellenbogen J. A., O'Malley B. W., Katzenellenbogen B. S. Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones. Mol. Endocrinol. 10:1996;119-131.
23. 2. Toxicol. Appl. Pharmacol. 137:1996;90-99.
24. Lee I. P., Suzuki K. Induction of aryl hydrocarbon hydroxylase activity in the rat prostate glands by 2,3,7,8-tetrachlorodibenzo-p. J. Pharmacol. Exp. Ther. 215:1980;601-605.
25. Li X., Weber L. W., Rozman K. K. Toxicokinetics of 2,3,7,8-tetrachlorodibenzo-p. Fundam. Appl. Toxicol. 27:1995;70-76.
26. Liang P., Pardee A. B. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science. 257:1992;967-971.
27. Lindebro M. C., Poellinger L., Whitelaw M. L. Protein-protein interaction via PAS domains: Role of the PAS domain in positive and negative regulation of the bHLH/PAS dioxin receptor-ARNT transcription factor complex. EMBO J. 14:1995;3528-3539.
28. Lopes E. S., Foster B. A., Donjacour A. A., Cunha G. R. Initiation of secretory activity of rat prostatic epithelium in organ culture. Endocrinology. 137:1996;4225-4234.
29. Mably T. A., Moore R. W., Peterson R. E. In uterop. Toxicol. Appl. Pharmacol. 114:1992;97-107.
30. Moore R. W., Potter C. L., Theobald H. M., Robinson J. A., Peterson R. E. Androgenic deficiency in male rats treated with 2,3,7,8-tetrachlorodibenzo-p. Toxicol. Appl. Pharmacol. 79:1985;99-111.
31. Neal R. A., Beatty P. W., Gasiewicz T. A. Studies on the mechanism of toxicity of 2,3,7,8-tetrachlorodibenzo-p. Ann. N.Y. Acad. Sci. 320:1979;204-213.
32. Okey A. B., Bondy G. P., Mason M. E., Kahl G. F., Eisen H. J., Guenthner T. M., Nebert D. W. Regulatory gene product of theAh. J. Biol. Chem. 254:1979;11636-11648.
33. Page M. J., Parker M. G. Effect of androgen on the transcription of rat prostatic binding protein genes. Mol. Cell. Endocrinol. 27:1982;343-355.
34. Poland A., Glover E. 2,3,7,8-Tetrachlorodibenzo-p. Mol. Pharmacol. 17:1980;86-94.
35. Poland A., Glover E., Kende A. S. Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p. J. Biol. Chem. 251:1976;4936-4946.
36. Poland A., Knutson J. C. 2,3,7,8-Tetrachlorodibenzo-p. Annu. Rev. Pharmacol. Toxicol. 22:1982;517-554.
37. Prins G. S., Birch L. The developmental pattern of androgen receptor expression in the rat prostate lobes is altered following neonatal exposure to estrogen. Endocrinology. 136:1995;1303-1314.
38. Rennie P. S., Bruchovsky N., Leco K. J., Sheppard P. C., McQueen S. A., Cheng H., Snoek R., Hamel A., Bock M. E., MacDonald B. S., Nickel B. E., Chang C., Liao S., Cattini P. A., Matusik R. J. Characterization of twocis. Mol. Endocrinol. 7:1993;23-36.
39. Roman B. L., Pollenz R. S., Peterson R. E. Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-p. Toxicol. Appl. Pharmacol. 150:1998a;228-239.
40. Roman B. L., Sommer R. J., Shinomiya K., Peterson R. E. In uterop. Toxicol. Appl. Pharmacol. 134:1995;241-250.
41. Roman B. L., Timms B. G., Prins G. S., Peterson R. E. In uterop. Toxicol. Appl. Pharmacol. 150:1998b;254-270.
42. Romkes M., Piskorska-Pliszczynska J., Safe S. Effects of 2,3,7,8-tetrachlorodibenzo-p. Toxicol. Appl. Pharmacol. 87:1987;306-314.
43. Romkes M., Safe S. Comparative activities of 2,3,7,8-tetrachlorodibenzo-p. Toxicol. Appl. Pharmacol. 92:1988;368-380.
44. Rowlands J. C., McEwan I. J., Gustafsson J.-Å. Trans. Mol. Pharmacol. 50:1996;528-548.
45. Schmidt J. V., Bradfield C. A. Ah receptor signaling pathways. Annu. Rev. Cell Dev. Biol. 12:1996;55-89.
46. Schmidt J. V., Carver L. A., Bradfield C. A. Molecular characterization of the murineAhr. J. Biol. Chem. 268:1993;22203-22209.
47. Selmin O., Lucier G. W., Clark G. C., Tritscher A. M., Vanden Heuvel J. P., Gastel J. A., Walker N. J., Sutter T. R., Bell D. A. Isolation and characterization of a novel gene induced by 2,3,7,8-tetrachlorodibenzo-p. Carcinogenesis. 17:1996;2609-2615.
48. Söderkvist P., Poellinger L., Gustafsson J.-Å. Carcinogen-binding proteins in the rat ventral prostate: Specific and nonspecific high-affinity binding sites for benzo(a)pyrene, 3-methylcholanthrene, and 2,3,7,8-tetrachlorodibenzo-p. Cancer Res. 46:1986;651-657.
49. Söderkvist P., Poellinger L. Involvement of the prostatic steroid-binding protein in the transfer of ligand to the dioxin receptor. Carcinogenesis. 8:1987;1287-1290.
50. Sutter T. R., Guzman K., Dold K. M., Greenlee W. F. Targets for dioxin: Genes for plasminogen activator inhibitor-2 and interleukin 1-β Science. 254:1991;415-418.
51. Sweetland R., Sheppard P. C., Dodd J. G., Matusik R. J. Post-castration rebound of an androgen regulated prostatic gene. Mol. Cell. Biochem. 84:1988;3-15.
52. Van den Berg M., Heeremans C., Veenhoven E., Olie K. Transfer of polychlorinated dibenzo-p. Fundam. Appl. Toxicol. 9:1987;635-644.
53. Vercaeren I., Vanaken H., Devos A., Peeters B., Verhoeven G., Heyns W. Androgens transcriptionally regulate the expression of cystatin-related protein and the C3 component of prostatic binding protein in rat ventral prostate and lacrimal gland. Endocrinology. 137:1996;4713-4720.
54. Wang X., Harris P. K., Ulrich R. G., Voorman R. L. Identification of dioxin-responsive genes in Hep G2 cells using differential mRNA display RT-PCR. Biochem. Biophys. Res. Commun. 220:1996;784-788.
55. Wilson C. M., McPhaul M. J. A and B forms of the androgen receptor are expressed in a variety of human tissues. Mol. Cell. Endocrinol. 120:1996;51-57.
56. Winderickx J., Hemschoote K., De Clercq N., Van Dijck P., Peeters B., Rombauts W., Verhoeven G., Heyns W. Tissue-specific expression and androgen regulation of different genes encoding rat prostatic 22-kilodalton glycoproteins homologous to human and rat cystatin. Mol. Endocrinol. 4:1990;657-667.
57. Zhang Y. L., Zhou Z. X., Zhang Y. D., Parker M. G. Expression of androgen receptors and prostatic steroid-binding protein during development of the rat ventral prostate. J. Endocrinol. 117:1987;361-366.