Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on preimplantation mouse embryos

Toxicology

Volumn 174, Issue 2, 2002, Pages 119-129

  Wu, Qing ^a,b   Ohsako, Seiichiroh ^a,c   Baba, Tadashi ^b,c   Miyamoto, Kyoko ^b   Tohyama, Chiharu ^a,c  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

AhR; Apoptosis; Arnt; CYP1A1; Dose dependent; Preimplantation embryo; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CARRIER PROTEIN; CYTOCHROME P450 1A1; GLOBIN; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLASTOCYST; CELL COUNT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO; EMBRYOTOXICITY; EXPOSURE; FEMALE; GENE EXPRESSION; MALE; MOUSE; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REIMPLANTATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; APOPTOSIS; BLASTOCYST; CELL COUNT; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MICE; MICE, INBRED ICR; PREGNANCY; RECEPTORS, ARYL HYDROCARBON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRACHLORODIBENZODIOXIN;

EID: 0037166042     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(02)00047-1     Document Type: Article

References (24)

1. RT-PCR quantification of AHR, ARNT, GR, and CYP1A1 mRNA in craniofacial tissues of embryonic mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone
2. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) accelerates differentiation of murine preimplantation embryos in vitro
3. Effects of TCDD on Ah receptor, Arnt, EGF, and TGF-α expression in embryonic mouse urinary tract
4. A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: Recent advances toward understanding the mechanism
5. Markedly increased constitutive CYP1A1 mRNA levels in the fertilized ovum of the mouse
6. The transition from maternal to embryonic control in the 2-cell mouse embryo
7. Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos
8. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin administered to pregnant rats during the preimplantation period
9. A rapid procedure for visualizing the inner cell mass and trophectoderm nuclei of mouse blastocysts in situ using polynucleotide-specific fluorochromes
10. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the expression of cytochrome P4501A1, the aryl hydrocarbon receptor, and the aryl hydrocarbon receptor muclear translocator in rat brain and pituitary
11. Expression and regulation of genes associated with cell death during murine preimplantation embryo development
12. Effect of dioxin, an environmental pollutant, on mouse blastocyst development and apoptosis
13. Three-generation reproduction study of rats given 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the diet
14. Quantification of mRNA by non-radioactive RT-PCR and CCD imaging system
15. Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis
16. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
17. Evidence that murine preimplantation embryos express aryl hydrocarbon receptor
18. Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Ah receptor and ARNT expression, CYP1A1 induction, and Ah receptor down-regulation
19. Presence of dioxins in human follicular fluid: Their possible stage-specific action on the development of preimplantation mouse embryos
20. The cell biology of blastocyst development
21. Induction of cytochrome P4501A1
22. Reproductive, neuroendocrine, and immune consequences of acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in the siberian hamster
23. Non-radioisotopic quantitative RT-PCR to detect changes in mRNA levels during early mouse embryo development
24. Cell surface interaction induces polarization of mouse 8-cell blastomeres at compaction