-
1
-
-
0028267440
-
Normal and abnormal biology of the beta-amyloid precursor protein
-
Selkoe DJ. Normal and abnormal biology of the beta-amyloid precursor protein. Annu Rev Neurosci 17: 489-517 (1994).
-
(1994)
Annu Rev Neurosci
, vol.17
, pp. 489-517
-
-
Selkoe, D.J.1
-
2
-
-
0028898888
-
Mechanisms of synaptic dysfunction in Alzheimer's disease
-
Masliah E. Mechanisms of synaptic dysfunction in Alzheimer's disease. Histol Histopathol 10: 509-519 (1995).
-
(1995)
Histol Histopathol
, vol.10
, pp. 509-519
-
-
Masliah, E.1
-
3
-
-
0030809128
-
Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments
-
Cullen W K, Suh YH, Anwyl R and Rowan MJ. Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments. Neuroreport 8: 3213-3217 (1997).
-
(1997)
Neuroreport
, vol.8
, pp. 3213-3217
-
-
Cullen, W.K.1
Suh, Y.H.2
Anwyl, R.3
Rowan, M.J.4
-
4
-
-
0032754051
-
Impairments of long-term potentiation in hippocampal slices of beta-amyloid-infused rats
-
Itoh A, Akaike T, Sokabe M, Nitta A, Iida R, Olariu A, et al. Impairments of long-term potentiation in hippocampal slices of beta-amyloid-infused rats. Eur J Pharmacol 382: 167-175 (1999).
-
(1999)
Eur J Pharmacol
, vol.382
, pp. 167-175
-
-
Itoh, A.1
Akaike, T.2
Sokabe, M.3
Nitta, A.4
Iida, R.5
Olariu, A.6
-
5
-
-
0036792096
-
Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling
-
USA
-
Vitolo OV, Sant'Angelo A, Costanzo V, Battaglia F, Arancio O and Shelanski M. Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling. Proc Natl Acad Sci USA 99: 13217-21 (2002).
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 13217-13221
-
-
Vitolo, O.V.1
Sant'Angelo, A.2
Costanzo, V.3
Battaglia, F.4
Arancio, O.5
Shelanski, M.6
-
6
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416: 535-539 (2002).
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
-
7
-
-
0032006678
-
The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways
-
Kelly JW. The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways. Curr Opin Struct Biol 8: 101-106 (1998).
-
(1998)
Curr Opin Struct Biol
, vol.8
, pp. 101-106
-
-
Kelly, J.W.1
-
8
-
-
0035961329
-
The structural basis of protein folding and its links with human disease
-
Dobson CM. The structural basis of protein folding and its links with human disease. Philos Trans R Soc Lond B Biol Sci 356: 133-145 (2001).
-
(2001)
Philos Trans R Soc Lond B Biol Sci
, vol.356
, pp. 133-145
-
-
Dobson, C.M.1
-
9
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
-
USA
-
Lambert MP, Barlow AK, Chromy BA, Edwards C, Freed R, Liosatos M, et al. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci USA 95: 6448-6453 (1998).
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
-
10
-
-
0033570337
-
Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
-
Hartley DM, Walsh DM, Ye CP, Diehl T, Vasquez S, Vassilev PM, Teplow DB, et al. Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J Neurosci 19: 8876-8884 (1999).
-
(1999)
J Neurosci
, vol.19
, pp. 8876-8884
-
-
Hartley, D.M.1
Walsh, D.M.2
Ye, C.P.3
Diehl, T.4
Vasquez, S.5
Vassilev, P.M.6
Teplow, D.B.7
-
11
-
-
0032845739
-
The nonfibrillar amyloid beta-peptide induces apoptotic neuronal cell death: Involvement of its C-terminal fusogenic domain
-
Pillot T, Drouet B, Queille S, Labeur C, Vandekerchkhove J, Rosseneu M, et al. The nonfibrillar amyloid beta-peptide induces apoptotic neuronal cell death: involvement of its C-terminal fusogenic domain. J Neurochem 73: 1626-1634 (1999).
-
(1999)
J Neurochem
, vol.73
, pp. 1626-1634
-
-
Pillot, T.1
Drouet, B.2
Queille, S.3
Labeur, C.4
Vandekerchkhove, J.5
Rosseneu, M.6
-
12
-
-
0033986987
-
Inhibition of A beta fibril formation and A beta-induced cytotoxicity by senile plaque-associated proteins
-
Monji A, Yoshida I, Tashiro K, Hayashi Y, Matsuda K and Tashiro N. Inhibition of A beta fibril formation and A beta-induced cytotoxicity by senile plaque-associated proteins. Neurosci Lett 278: 81-84 (2000).
-
(2000)
Neurosci Lett
, vol.278
, pp. 81-84
-
-
Monji, A.1
Yoshida, I.2
Tashiro, K.3
Hayashi, Y.4
Matsuda, K.5
Tashiro, N.6
-
13
-
-
0033520461
-
Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates
-
Walsh DM, Hartley DM, Kusumoto Y, Fezoui Y, Condron MM, Lomakin A, et al. Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates. J Biol Chem 274: 25945-25952 (1999).
-
(1999)
J Biol Chem
, vol.274
, pp. 25945-25952
-
-
Walsh, D.M.1
Hartley, D.M.2
Kusumoto, Y.3
Fezoui, Y.4
Condron, M.M.5
Lomakin, A.6
-
14
-
-
0033771793
-
Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease?
-
Goldberg MS and Lansbury PTJr. Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease? Nat Cell Biol 2: E115-9 (2000).
-
(2000)
Nat Cell Biol
, vol.2
-
-
Goldberg, M.S.1
Lansbury Jr., P.T.2
-
15
-
-
0034681163
-
Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy
-
USA
-
Conway KA, Lee SJ, Rochet JC, Ding TT, Williamson RE and Lansbury PT Jr. Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy. Proc Natl Acad Sci USA 97: 571-576 (2000).
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.J.2
Rochet, J.C.3
Ding, T.T.4
Williamson, R.E.5
Lansbury Jr., P.T.6
-
16
-
-
0034089960
-
Fresh and nonfibrillar amyloid beta protein(1-40) induces rapid cellular degeneration in aged human fibroblasts: Evidence for AbetaP-channel-mediated cellular toxicity
-
Zhu YJ, Lin H and Lal R. Fresh and nonfibrillar amyloid beta protein(1-40) induces rapid cellular degeneration in aged human fibroblasts: evidence for AbetaP-channel-mediated cellular toxicity. FASEB J 14: 1244-1254 (2000).
-
(2000)
FASEB J
, vol.14
, pp. 1244-1254
-
-
Zhu, Y.J.1
Lin, H.2
Lal, R.3
-
17
-
-
0025992417
-
In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity
-
Pike CJ, Walencewicz AJ, Glabe CG and Cotman CW. In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res 563: 311-314 (1991).
-
(1991)
Brain Res
, vol.563
, pp. 311-314
-
-
Pike, C.J.1
Walencewicz, A.J.2
Glabe, C.G.3
Cotman, C.W.4
-
18
-
-
0028172886
-
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red
-
USA
-
Lorenzo A and Yankner BA. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc Natl Acad Sci USA 91: 12243-12247 (1994).
-
(1994)
Proc Natl Acad Sci
, vol.91
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
19
-
-
0036848056
-
A novel beta-sheet breaker, RS-0406, reverses amyloid beta-induced cytotoxicity and impairment of long-term potentiation in vitro
-
Nakagami Y, Nishimura S, Murasugi T, Kaneko I, Meguro M, Marumoto S,, et al. A novel beta-sheet breaker, RS-0406, reverses amyloid beta-induced cytotoxicity and impairment of long-term potentiation in vitro. Br J Pharmacol 137: 676-682 (2002).
-
(2002)
Br J Pharmacol
, vol.137
, pp. 676-682
-
-
Nakagami, Y.1
Nishimura, S.2
Murasugi, T.3
Kaneko, I.4
Meguro, M.5
Marumoto, S.6
-
20
-
-
14944378094
-
Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation
-
Walsh DM, Townsend M, Podlisny MB, Shankar GM, Fadeeva JV, Agnaf OE et al. Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation. J Neurosci 25: 2455-2462 (2005).
-
(2005)
J Neurosci
, vol.25
, pp. 2455-2462
-
-
Walsh, D.M.1
Townsend, M.2
Podlisny, M.B.3
Shankar, G.M.4
Fadeeva, J.V.5
Agnaf, O.E.6
-
21
-
-
3042798841
-
Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide
-
Wang Q, Rowan MJ and Anwyl R. Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide. J Neurosci 24: 6049-6056 (2004).
-
(2004)
J Neurosci
, vol.24
, pp. 6049-6056
-
-
Wang, Q.1
Rowan, M.J.2
Anwyl, R.3
-
22
-
-
16644379264
-
Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function
-
Cleary JP, Walsh DM, Hofmeister JJ, Shankar GM, Kuskowski MA, Selkoe DJ, et al. Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function. Nat Neurosci 8: 79-84 (2005).
-
(2005)
Nat Neurosci
, vol.8
, pp. 79-84
-
-
Cleary, J.P.1
Walsh, D.M.2
Hofmeister, J.J.3
Shankar, G.M.4
Kuskowski, M.A.5
Selkoe, D.J.6
-
23
-
-
0038176528
-
In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis
-
Stine WB Jr, Dahlgren KN, Krafft GA and LaDu MJ. In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis. J Biol Chem 278: 11612-11622 (2003).
-
(2003)
J Biol Chem
, vol.278
, pp. 11612-11622
-
-
Stine Jr., W.B.1
Dahlgren, K.N.2
Krafft, G.A.3
Ladu, M.J.4
-
24
-
-
0036547110
-
Peptide inhibitors of beta amyloid aggregation
-
Findeis MA. Peptide inhibitors of beta amyloid aggregation. Curr Top Med Chem 2: 417-423 (2002).
-
(2002)
Curr Top Med Chem
, vol.2
, pp. 417-423
-
-
Findeis, M.A.1
-
25
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner GG and Wong CW. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 120: 885-890 (1984).
-
(1984)
Biochem Biophys Res Commun
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
26
-
-
0022156464
-
Neuronal origin of a cerebral amyloid: Neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels
-
Masters CL, Multhaup G, Simms G, Pottgiesser J, Martins RN and Beyreuther K. Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels. EMBO J 4: 2757-2763 (1985).
-
(1985)
EMBO J
, vol.4
, pp. 2757-2763
-
-
Masters, C.L.1
Multhaup, G.2
Simms, G.3
Pottgiesser, J.4
Martins, R.N.5
Beyreuther, K.6
-
27
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325: 733-736 (1987).
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
-
28
-
-
0026646604
-
Amyloid beta-peptide is produced by cultured cells during normal metabolism
-
Haass C, Schlossmacher MG, Hung AY, Vigo-Pelfrey C, Mellon A, Ostaszewski BL, et al. Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature 359: 322-325 (1992).
-
(1992)
Nature
, vol.359
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.G.2
Hung, A.Y.3
Vigo-Pelfrey, C.4
Mellon, A.5
Ostaszewski, B.L.6
-
29
-
-
0026646605
-
Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids
-
Seubert P, Vigo-Pelfrey C, Esch F, Lee M, Dovey H, Davis D, et al. Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids. Nature 359: 325-327 (1992).
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
Lee, M.4
Dovey, H.5
Davis, D.6
-
30
-
-
0026760261
-
Production of the Alzheimer amyloid beta protein by normal proteolytic processing
-
Shoji M, Golde TE, Ghiso J, Cheung TT, Estus S, Shaffer LM, et al. Production of the Alzheimer amyloid beta protein by normal proteolytic processing. Science 258: 126-129 (1992).
-
(1992)
Science
, vol.258
, pp. 126-129
-
-
Shoji, M.1
Golde, T.E.2
Ghiso, J.3
Cheung, T.T.4
Estus, S.5
Shaffer, L.M.6
-
31
-
-
0027407570
-
Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells
-
USA
-
Busciglio J, Gabuzda DH, Matsudaira P and Yankner BA. Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells. Proc Natl Acad Sci USA 90: 2092-2096 (1993).
-
(1993)
Proc Natl Acad Sci
, vol.90
, pp. 2092-2096
-
-
Busciglio, J.1
Gabuzda, D.H.2
Matsudaira, P.3
Yankner, B.A.4
-
32
-
-
0034516988
-
Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein
-
Selkoe DJ. Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein. Ann N Y Acad Sci 924: 17-25 (2000).
-
(2000)
Ann N Y Acad Sci
, vol.924
, pp. 17-25
-
-
Selkoe, D.J.1
-
33
-
-
0025056563
-
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport
-
USA
-
Koo EH, Sisodia SS, Archer DR, Martin LJ, Weidemann A, Beyreuther K, et al. Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport. Proc Natl Acad Sci USA 87: 1561-1565 (1990).
-
(1990)
Proc Natl Acad Sci
, vol.87
, pp. 1561-1565
-
-
Koo, E.H.1
Sisodia, S.S.2
Archer, D.R.3
Martin, L.J.4
Weidemann, A.5
Beyreuther, K.6
-
34
-
-
0028913471
-
Trafficking of cell surface beta-amyloid precursor protein: Retrograde and transcytotic transport in cultured neurons
-
Yamazaki T, Selkoe DJ and Koo EH. Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons. J Cell Biol 129: 431-442 (1995).
-
(1995)
J Cell Biol
, vol.129
, pp. 431-442
-
-
Yamazaki, T.1
Selkoe, D.J.2
Koo, E.H.3
-
35
-
-
0026432318
-
Seminars in medicine of the Beth Israel Hospital, Boston. beta-Amyloid and the pathogenesis of Alzheimer's disease
-
Yankner BA and Mesulam MM. Seminars in medicine of the Beth Israel Hospital, Boston. beta-Amyloid and the pathogenesis of Alzheimer's disease. N Engl J Med 325: 1849-1857 (1991).
-
(1991)
N Engl J Med
, vol.325
, pp. 1849-1857
-
-
Yankner, B.A.1
Mesulam, M.M.2
-
36
-
-
2542584749
-
Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice
-
Trinchese F, Liu S, Battaglia F, Walter S, Mathews PM and Arancio O. Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice. Ann Neurol 55: 801-814 (2004).
-
(2004)
Ann Neurol
, vol.55
, pp. 801-814
-
-
Trinchese, F.1
Liu, S.2
Battaglia, F.3
Walter, S.4
Mathews, P.M.5
Arancio, O.6
-
37
-
-
0033523480
-
Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice
-
Larson J, Lynch G, Games D and Seubert P. Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice. Brain Res 840: 23-35 (1999).
-
(1999)
Brain Res
, vol.840
, pp. 23-35
-
-
Larson, J.1
Lynch, G.2
Games, D.3
Seubert, P.4
-
38
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
USA
-
Hsia AY, Masliah E, McConlogue L, Yu GQ, Tatsuno G, Hu K, et al. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc Natl Acad Sci USA 96: 3228-3233 (1999).
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
Yu, G.Q.4
Tatsuno, G.5
Hu, K.6
-
39
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
-
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 39: 409-421 (2003).
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
-
40
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, et al. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274: 99-102 (1996).
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
-
41
-
-
0035399822
-
Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant form of amyloid precursor protein
-
Fitzjohn SM, Morton RA, Kuenzi F, Rosahl TW, Shearman M, Lewis H, et al. Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant form of amyloid precursor protein. J Neurosci 21: 4691-4698 (2001).
-
(2001)
J Neurosci
, vol.21
, pp. 4691-4698
-
-
Fitzjohn, S.M.1
Morton, R.A.2
Kuenzi, F.3
Rosahl, T.W.4
Shearman, M.5
Lewis, H.6
-
42
-
-
0033525520
-
Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain
-
Moechars D, Dewachter I, Lorent K, Reverse D, Baekelandt V, Naidu A, et al. Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain. J Biol Chem 274: 6483-6492 (1999).
-
(1999)
J Biol Chem
, vol.274
, pp. 6483-6492
-
-
Moechars, D.1
Dewachter, I.2
Lorent, K.3
Reverse, D.4
Baekelandt, V.5
Naidu, A.6
-
43
-
-
0030978998
-
Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein
-
Nalbantoglu J, Tirado-Santiago G, Lahsaini A, Poirier J, Goncalves O, Verge G, et al. Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein. Nature 387: 500-505 (1997).
-
(1997)
Nature
, vol.387
, pp. 500-505
-
-
Nalbantoglu, J.1
Tirado-Santiago, G.2
Lahsaini, A.3
Poirier, J.4
Goncalves, O.5
Verge, G.6
-
44
-
-
11144353586
-
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease
-
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, et al. ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science 304: 448-452 (2004).
-
(2004)
Science
, vol.304
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
-
45
-
-
20144388830
-
ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction
-
Takuma K, Yao J, Huang J, Xu H, Chen X, Luddy J, et al. ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction. FASEB J 19: 597-598 (2005).
-
(2005)
FASEB J
, vol.19
, pp. 597-598
-
-
Takuma, K.1
Yao, J.2
Huang, J.3
Xu, H.4
Chen, X.5
Luddy, J.6
-
46
-
-
8144223671
-
RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice
-
Arancio O, Zhang HP, Chen X, Lin C, Trinchese F, Puzzo D, et al. RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice. EMBO J 23: 4096-4105 (2004).
-
(2004)
EMBO J
, vol.23
, pp. 4096-4105
-
-
Arancio, O.1
Zhang, H.P.2
Chen, X.3
Lin, C.4
Trinchese, F.5
Puzzo, D.6
-
47
-
-
0035875962
-
Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease
-
Dineley KT, Westerman M, Bui D, Bell K, Ashe KH and Sweatt JD. Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease. J Neurosci 21: 4125-4133 (2001).
-
(2001)
J Neurosci
, vol.21
, pp. 4125-4133
-
-
Dineley, K.T.1
Westerman, M.2
Bui, D.3
Bell, K.4
Ashe, K.H.5
Sweatt, J.D.6
-
48
-
-
0034648038
-
SB203580, the p38 mitogena-ctivated protein kinase inhibitor blocks the inhibitory effect of beta-amyloid on long-term potentiation in the rat hippocampus
-
Saleshando G and O'Connor JJ. SB203580, the p38 mitogena-ctivated protein kinase inhibitor blocks the inhibitory effect of beta-amyloid on long-term potentiation in the rat hippocampus. Neurosci Lett 288: 119-22 (2000).
-
(2000)
Neurosci Lett
, vol.288
, pp. 119-122
-
-
Saleshando, G.1
O'Connor, J.J.2
-
49
-
-
22544485048
-
Amyloid-beta peptide inhibits activation of the nitric oxide/cGMP/cAMP-responsive element-binding protein pathway during hippocampal synaptic plasticity
-
Puzzo D, Vitolo O, Trinchese F, Jacob JP, Palmeri A and Arancio O. Amyloid-beta peptide inhibits activation of the nitric oxide/cGMP/cAMP- responsive element-binding protein pathway during hippocampal synaptic plasticity. J Neurosci 25: 6887-97 (2005).
-
(2005)
J Neurosci
, vol.25
, pp. 6887-6897
-
-
Puzzo, D.1
Vitolo, O.2
Trinchese, F.3
Jacob, J.P.4
Palmeri, A.5
Arancio, O.6
-
50
-
-
14844315768
-
Amyloid beta prevents activation of calcium/calmodulin-dependent protein kinase II and AMPA receptor phosphorylation during hippocampal long-term potentiation
-
Zhao D, Watson JB and Xie CW. Amyloid beta prevents activation of calcium/calmodulin-dependent protein kinase II and AMPA receptor phosphorylation during hippocampal long-term potentiation. J Neurophysiol 92: 2853-2858 (2004).
-
(2004)
J Neurophysiol
, vol.92
, pp. 2853-2858
-
-
Zhao, D.1
Watson, J.B.2
Xie, C.W.3
-
51
-
-
0028170035
-
cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase
-
Huang YY, Li XC and Kandel ER. cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase. Cell 79: 69-79 (1994).
-
(1994)
Cell
, vol.79
, pp. 69-79
-
-
Huang, Y.Y.1
Li, X.C.2
Kandel, E.R.3
-
52
-
-
0028051845
-
Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP
-
Weisskopf MG, Castillo PE, Zalutsky RA and Nicoll RA. Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP. Science 265: 1878-1882 (1994).
-
(1994)
Science
, vol.265
, pp. 1878-1882
-
-
Weisskopf, M.G.1
Castillo, P.E.2
Zalutsky, R.A.3
Nicoll, R.A.4
-
53
-
-
17444438298
-
The extracellular signal-regulated kinase cascade is required for NMDA receptor-independent LTP in area CA1 but not area CA3 of the hippocampus
-
Kanterewicz BI, Urban NN, McMahon DB, Norman ED, Giffen LJ, Favata MF, et al. The extracellular signal-regulated kinase cascade is required for NMDA receptor-independent LTP in area CA1 but not area CA3 of the hippocampus. J Neurosci 20: 3057-3066 (2000).
-
(2000)
J Neurosci
, vol.20
, pp. 3057-3066
-
-
Kanterewicz, B.I.1
Urban, N.N.2
McMahon, D.B.3
Norman, E.D.4
Giffen, L.J.5
Favata, M.F.6
-
54
-
-
0027203084
-
Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons
-
Frey U, Huang YY and Kandel ER. Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons. Science 260: 1661-1664 (1993).
-
(1993)
Science
, vol.260
, pp. 1661-1664
-
-
Frey, U.1
Huang, Y.Y.2
Kandel, E.R.3
-
55
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini M, Giannoni E, Chiti F, Baroni F, Formigli L, Zurdo J, et al. Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature 416: 507-511 (2002).
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
-
56
-
-
0037073604
-
A novel compound RS-0466 reverses beta-amyloid-induced cytotoxicity through the Akt signaling pathway in vitro
-
Nakagami Y, Nishimura S, Murasugi T, Kubo T, Kaneko I, Meguro M, et al. A novel compound RS-0466 reverses beta-amyloid-induced cytotoxicity through the Akt signaling pathway in vitro. Eur J Pharmacol 457: 11-17 (2002).
-
(2002)
Eur J Pharmacol
, vol.457
, pp. 11-17
-
-
Nakagami, Y.1
Nishimura, S.2
Murasugi, T.3
Kubo, T.4
Kaneko, I.5
Meguro, M.6
-
57
-
-
21044453723
-
Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo
-
Klyubin I, Walsh DM, Lemere CA, Cullen WK, Shankar GM, Betts V, et al. Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo. Nat Med 11: 556-561 (2005).
-
(2005)
Nat Med
, vol.11
, pp. 556-561
-
-
Klyubin, I.1
Walsh, D.M.2
Lemere, C.A.3
Cullen, W.K.4
Shankar, G.M.5
Betts, V.6
|