메뉴 건너뛰기




Volumn 11, Issue 1, 2006, Pages 81-92

HIF-Dependent Hematopoietic Factors Regulate the Development of the Embryonic Vasculature

Author keywords

DEVBIO

Indexed keywords

ATAXIN 1; GROWTH FACTOR; HYPOXIA INDUCIBLE FACTOR 1BETA; RECOMBINANT VASCULOTROPIN;

EID: 33745490023     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2006.04.018     Document Type: Article
Times cited : (89)

References (60)
  • 1
    • 0033214848 scopus 로고    scopus 로고
    • Multilineage embryonic hematopoiesis requires hypoxic ARNT activity
    • Adelman D.M., Maltepe E., and Simon M.C. Multilineage embryonic hematopoiesis requires hypoxic ARNT activity. Genes Dev. 13 (1999) 2478-2483
    • (1999) Genes Dev. , vol.13 , pp. 2478-2483
    • Adelman, D.M.1    Maltepe, E.2    Simon, M.C.3
  • 2
    • 0034671706 scopus 로고    scopus 로고
    • Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses
    • Adelman D.M., Gertsenstein M., Nagy A., Simon M.C., and Maltepe E. Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses. Genes Dev. 14 (2000) 3191-3203
    • (2000) Genes Dev. , vol.14 , pp. 3191-3203
    • Adelman, D.M.1    Gertsenstein, M.2    Nagy, A.3    Simon, M.C.4    Maltepe, E.5
  • 3
    • 18844442549 scopus 로고    scopus 로고
    • Regulation of hematopoietic stem cells by the niche
    • Arai F., Hirao A., and Suda T. Regulation of hematopoietic stem cells by the niche. Trends Cardiovasc. Med. 15 (2005) 75-79
    • (2005) Trends Cardiovasc. Med. , vol.15 , pp. 75-79
    • Arai, F.1    Hirao, A.2    Suda, T.3
  • 4
    • 13544251374 scopus 로고    scopus 로고
    • A novel role for vascular endothelial growth factor as an autocrine survival factor for embryonic stem cells during hypoxia
    • Brusselmans K., Bono F., Collen D., Herbert J.M., Carmeliet P., and Dewerchin M. A novel role for vascular endothelial growth factor as an autocrine survival factor for embryonic stem cells during hypoxia. J. Biol. Chem. 280 (2005) 3493-3499
    • (2005) J. Biol. Chem. , vol.280 , pp. 3493-3499
    • Brusselmans, K.1    Bono, F.2    Collen, D.3    Herbert, J.M.4    Carmeliet, P.5    Dewerchin, M.6
  • 5
    • 30744479430 scopus 로고    scopus 로고
    • Angiogenesis in life, disease and medicine
    • Carmeliet P. Angiogenesis in life, disease and medicine. Nature 438 (2005) 932-936
    • (2005) Nature , vol.438 , pp. 932-936
    • Carmeliet, P.1
  • 6
    • 0034095038 scopus 로고    scopus 로고
    • Transgenic mouse models in angiogenesis and cardiovascular disease
    • Carmeliet P., and Collen D. Transgenic mouse models in angiogenesis and cardiovascular disease. J. Pathol. 190 (2000) 387-405
    • (2000) J. Pathol. , vol.190 , pp. 387-405
    • Carmeliet, P.1    Collen, D.2
  • 7
    • 0037131271 scopus 로고    scopus 로고
    • Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha
    • Chan D.A., Sutphin P.D., Denko N.C., and Giaccia A.J. Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha. J. Biol. Chem. 277 (2002) 40112-40117
    • (2002) J. Biol. Chem. , vol.277 , pp. 40112-40117
    • Chan, D.A.1    Sutphin, P.D.2    Denko, N.C.3    Giaccia, A.J.4
  • 9
    • 0035983324 scopus 로고    scopus 로고
    • Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice
    • Compernolle V., Brusselmans K., Acker T., Hoet P., Tjwa M., Beck H., Plaisance S., Dor Y., Keshet E., Lupu F., et al. Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nat. Med. 8 (2002) 702-710
    • (2002) Nat. Med. , vol.8 , pp. 702-710
    • Compernolle, V.1    Brusselmans, K.2    Acker, T.3    Hoet, P.4    Tjwa, M.5    Beck, H.6    Plaisance, S.7    Dor, Y.8    Keshet, E.9    Lupu, F.10
  • 10
    • 30744432619 scopus 로고    scopus 로고
    • Endothelial cells and VEGF in vascular development
    • Coultas L., Chawengsaksophak K., and Rossant J. Endothelial cells and VEGF in vascular development. Nature 438 (2005) 937-945
    • (2005) Nature , vol.438 , pp. 937-945
    • Coultas, L.1    Chawengsaksophak, K.2    Rossant, J.3
  • 11
    • 16844386959 scopus 로고    scopus 로고
    • Targeted replacement of hypoxia-inducible factor-1alpha by a hypoxia-inducible factor-2α knock-in allele promotes tumor growth
    • Covello K.L., Simon M.C., and Keith B. Targeted replacement of hypoxia-inducible factor-1alpha by a hypoxia-inducible factor-2α knock-in allele promotes tumor growth. Cancer Res. 65 (2005) 2277-2286
    • (2005) Cancer Res. , vol.65 , pp. 2277-2286
    • Covello, K.L.1    Simon, M.C.2    Keith, B.3
  • 14
    • 0036285647 scopus 로고    scopus 로고
    • Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta
    • de Bruijn M.F., Ma X., Robin C., Ottersbach K., Sanchez M.J., and Dzierzak E. Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta. Immunity 16 (2002) 673-683
    • (2002) Immunity , vol.16 , pp. 673-683
    • de Bruijn, M.F.1    Ma, X.2    Robin, C.3    Ottersbach, K.4    Sanchez, M.J.5    Dzierzak, E.6
  • 16
    • 0031000736 scopus 로고    scopus 로고
    • A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development
    • Ema M., Taya S., Yokotani N., Sogawa K., Matsuda Y., and Fujii-Kuriyama Y. A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development. Proc. Natl. Acad. Sci. USA 94 (1997) 4273-4278
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4273-4278
    • Ema, M.1    Taya, S.2    Yokotani, N.3    Sogawa, K.4    Matsuda, Y.5    Fujii-Kuriyama, Y.6
  • 19
    • 4444257379 scopus 로고    scopus 로고
    • The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease
    • Giaccia A.J., Simon M.C., and Johnson R. The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease. Genes Dev. 18 (2004) 2183-2194
    • (2004) Genes Dev. , vol.18 , pp. 2183-2194
    • Giaccia, A.J.1    Simon, M.C.2    Johnson, R.3
  • 20
    • 0345491599 scopus 로고    scopus 로고
    • Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
    • Hu C.J., Wang L.Y., Chodosh L.A., Keith B., and Simon M.C. Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Mol. Cell. Biol. 23 (2003) 9361-9374
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 9361-9374
    • Hu, C.J.1    Wang, L.Y.2    Chodosh, L.A.3    Keith, B.4    Simon, M.C.5
  • 21
    • 23944518957 scopus 로고    scopus 로고
    • Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells
    • Ingram D.A., Caplice N.M., and Yoder M.C. Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells. Blood 106 (2005) 1525-1531
    • (2005) Blood , vol.106 , pp. 1525-1531
    • Ingram, D.A.1    Caplice, N.M.2    Yoder, M.C.3
  • 25
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • Jain R.K. Molecular regulation of vessel maturation. Nat. Med. 9 (2003) 685-693
    • (2003) Nat. Med. , vol.9 , pp. 685-693
    • Jain, R.K.1
  • 26
    • 0031971047 scopus 로고    scopus 로고
    • Expression of ARNT, ARNT2, HIF1 α, HIF2 α and Ah receptor mRNAs in the developing mouse
    • Jain S., Maltepe E., Lu M.M., Simon C., and Bradfield C.A. Expression of ARNT, ARNT2, HIF1 α, HIF2 α and Ah receptor mRNAs in the developing mouse. Mech. Dev. 73 (1998) 117-123
    • (1998) Mech. Dev. , vol.73 , pp. 117-123
    • Jain, S.1    Maltepe, E.2    Lu, M.M.3    Simon, C.4    Bradfield, C.A.5
  • 27
    • 0035044085 scopus 로고    scopus 로고
    • Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function
    • Kocher A.A., Schuster M.D., Szabolcs M.J., Takuma S., Burkhoff D., Wang J., Homma S., Edwards N.M., and Itescu S. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat. Med. 7 (2001) 430-436
    • (2001) Nat. Med. , vol.7 , pp. 430-436
    • Kocher, A.A.1    Schuster, M.D.2    Szabolcs, M.J.3    Takuma, S.4    Burkhoff, D.5    Wang, J.6    Homma, S.7    Edwards, N.M.8    Itescu, S.9
  • 29
    • 0033562569 scopus 로고    scopus 로고
    • Defective vascularization of HIF-1α-null embryos is not associated with VEGF deficiency but with mesenchymal cell death
    • Kotch L.E., Iyer N.V., Laughner E., and Semenza G.L. Defective vascularization of HIF-1α-null embryos is not associated with VEGF deficiency but with mesenchymal cell death. Dev. Biol. 209 (1999) 254-267
    • (1999) Dev. Biol. , vol.209 , pp. 254-267
    • Kotch, L.E.1    Iyer, N.V.2    Laughner, E.3    Semenza, G.L.4
  • 30
    • 0035142809 scopus 로고    scopus 로고
    • Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development
    • Lee Y.M., Jeong C.H., Koo S.Y., Son M.J., Song H.S., Bae S.K., Raleigh J.A., Chung H.Y., Yoo M.A., and Kim K.W. Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development. Dev. Dyn. 220 (2001) 175-186
    • (2001) Dev. Dyn. , vol.220 , pp. 175-186
    • Lee, Y.M.1    Jeong, C.H.2    Koo, S.Y.3    Son, M.J.4    Song, H.S.5    Bae, S.K.6    Raleigh, J.A.7    Chung, H.Y.8    Yoo, M.A.9    Kim, K.W.10
  • 32
    • 0035160312 scopus 로고    scopus 로고
    • Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
    • Lyden D., Hattori K., Dias S., Costa C., Blaikie P., Butros L., Chadburn A., Heissig B., Marks W., Witte L., et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat. Med. 7 (2001) 1194-1201
    • (2001) Nat. Med. , vol.7 , pp. 1194-1201
    • Lyden, D.1    Hattori, K.2    Dias, S.3    Costa, C.4    Blaikie, P.5    Butros, L.6    Chadburn, A.7    Heissig, B.8    Marks, W.9    Witte, L.10
  • 33
    • 0031969557 scopus 로고    scopus 로고
    • Oxygen, genes, and development: an analysis of the role of hypoxic gene regulation during murine vascular development
    • Maltepe E., and Simon M.C. Oxygen, genes, and development: an analysis of the role of hypoxic gene regulation during murine vascular development. J. Mol. Med. 76 (1998) 391-401
    • (1998) J. Mol. Med. , vol.76 , pp. 391-401
    • Maltepe, E.1    Simon, M.C.2
  • 34
    • 0030943461 scopus 로고    scopus 로고
    • Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT
    • Maltepe E., Schmidt J.V., Baunoch D., Bradfield C.A., and Simon M.C. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature 386 (1997) 403-407
    • (1997) Nature , vol.386 , pp. 403-407
    • Maltepe, E.1    Schmidt, J.V.2    Baunoch, D.3    Bradfield, C.A.4    Simon, M.C.5
  • 35
    • 0030595341 scopus 로고    scopus 로고
    • Definitive hematopoiesis is autonomously initiated by the AGM region
    • Medvinsky A., and Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 86 (1996) 897-906
    • (1996) Cell , vol.86 , pp. 897-906
    • Medvinsky, A.1    Dzierzak, E.2
  • 37
    • 0033134766 scopus 로고    scopus 로고
    • Mice homozygous for a truncated form of CREB-binding protein exhibit defects in hematopoiesis and vasculo-angiogenesis
    • Oike Y., Takakura N., Hata A., Kaname T., Akizuki M., Yamaguchi Y., Yasue H., Araki K., Yamamura K., and Suda T. Mice homozygous for a truncated form of CREB-binding protein exhibit defects in hematopoiesis and vasculo-angiogenesis. Blood 93 (1999) 2771-2779
    • (1999) Blood , vol.93 , pp. 2771-2779
    • Oike, Y.1    Takakura, N.2    Hata, A.3    Kaname, T.4    Akizuki, M.5    Yamaguchi, Y.6    Yasue, H.7    Araki, K.8    Yamamura, K.9    Suda, T.10
  • 39
    • 0034682513 scopus 로고    scopus 로고
    • The transcription factor EPAS-1/hypoxia-inducible factor 2α plays an important role in vascular remodeling
    • Peng J., Zhang L., Drysdale L., and Fong G.H. The transcription factor EPAS-1/hypoxia-inducible factor 2α plays an important role in vascular remodeling. Proc. Natl. Acad. Sci. USA 97 (2000) 8386-8391
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8386-8391
    • Peng, J.1    Zhang, L.2    Drysdale, L.3    Fong, G.H.4
  • 41
    • 15744369062 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis
    • Piret J.P., Minet E., Cosse J.P., Ninane N., Debacq C., Raes M., and Michiels C. Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis. J. Biol. Chem. 280 (2005) 9336-9344
    • (2005) J. Biol. Chem. , vol.280 , pp. 9336-9344
    • Piret, J.P.1    Minet, E.2    Cosse, J.P.3    Ninane, N.4    Debacq, C.5    Raes, M.6    Michiels, C.7
  • 42
    • 0038376000 scopus 로고    scopus 로고
    • Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration
    • Rafii S., and Lyden D. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat. Med. 9 (2003) 702-712
    • (2003) Nat. Med. , vol.9 , pp. 702-712
    • Rafii, S.1    Lyden, D.2
  • 43
    • 0034901617 scopus 로고    scopus 로고
    • Hypoxia-inducible factor and the development of stem cells of the cardiovascular system
    • Ramirez-Bergeron D.L., and Simon M.C. Hypoxia-inducible factor and the development of stem cells of the cardiovascular system. Stem Cells 19 (2001) 279-286
    • (2001) Stem Cells , vol.19 , pp. 279-286
    • Ramirez-Bergeron, D.L.1    Simon, M.C.2
  • 44
    • 6944233515 scopus 로고    scopus 로고
    • Hypoxia affects mesoderm and enhances hemangioblast specification during early development
    • Ramirez-Bergeron D.L., Runge A., Dahl K.D., Fehling H.J., Keller G., and Simon M.C. Hypoxia affects mesoderm and enhances hemangioblast specification during early development. Development 131 (2004) 4623-4634
    • (2004) Development , vol.131 , pp. 4623-4634
    • Ramirez-Bergeron, D.L.1    Runge, A.2    Dahl, K.D.3    Fehling, H.J.4    Keller, G.5    Simon, M.C.6
  • 45
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau W. Mechanisms of angiogenesis. Nature 386 (1997) 671-674
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 46
    • 0032100732 scopus 로고    scopus 로고
    • HIF-1α is required for solid tumor formation and embryonic vascularization
    • Ryan H.E., Lo J., and Johnson R.S. HIF-1α is required for solid tumor formation and embryonic vascularization. EMBO J. 17 (1998) 3005-3015
    • (1998) EMBO J. , vol.17 , pp. 3005-3015
    • Ryan, H.E.1    Lo, J.2    Johnson, R.S.3
  • 47
    • 0030483541 scopus 로고    scopus 로고
    • Characterization of the first definitive hematopoietic stem cells in the AGM and liver of the mouse embryo
    • Sanchez M.-J., Holmes A., Miles C., and Dzierzak E. Characterization of the first definitive hematopoietic stem cells in the AGM and liver of the mouse embryo. Immunity 5 (1996) 513-525
    • (1996) Immunity , vol.5 , pp. 513-525
    • Sanchez, M.-J.1    Holmes, A.2    Miles, C.3    Dzierzak, E.4
  • 48
    • 0032190614 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: master regulator of O2 homeostasis
    • Semenza G.L. Hypoxia-inducible factor 1: master regulator of O2 homeostasis. Curr. Opin. Genet. Dev. 8 (1998) 588-594
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 588-594
    • Semenza, G.L.1
  • 49
    • 0033233243 scopus 로고    scopus 로고
    • Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
    • Semenza G.L. Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu. Rev. Cell Dev. Biol. 15 (1999) 551-578
    • (1999) Annu. Rev. Cell Dev. Biol. , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 50
    • 0035884701 scopus 로고    scopus 로고
    • HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
    • Sowter H.M., Ratcliffe P.J., Watson P., Greenberg A.H., and Harris A.L. HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res. 61 (2001) 6669-6673
    • (2001) Cancer Res. , vol.61 , pp. 6669-6673
    • Sowter, H.M.1    Ratcliffe, P.J.2    Watson, P.3    Greenberg, A.H.4    Harris, A.L.5
  • 51
    • 0031869662 scopus 로고    scopus 로고
    • Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia
    • Stein I., Itin A., Einat P., Skaliter R., Grossman Z., and Keshet E. Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia. Mol. Cell. Biol. 18 (1998) 3112-3119
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3112-3119
    • Stein, I.1    Itin, A.2    Einat, P.3    Skaliter, R.4    Grossman, Z.5    Keshet, E.6
  • 53
    • 0032213752 scopus 로고    scopus 로고
    • Critical role of the TIE2 endothelial cell receptor in the development of definitive hematopoiesis
    • Takakura N., Huang X.L., Naruse T., Hamaguchi I., Dumont D.J., Yancopoulos G.D., and Suda T. Critical role of the TIE2 endothelial cell receptor in the development of definitive hematopoiesis. Immunity 9 (1998) 677-686
    • (1998) Immunity , vol.9 , pp. 677-686
    • Takakura, N.1    Huang, X.L.2    Naruse, T.3    Hamaguchi, I.4    Dumont, D.J.5    Yancopoulos, G.D.6    Suda, T.7
  • 55
    • 7944224442 scopus 로고    scopus 로고
    • Loss of HIF-1α in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis
    • Tang N., Wang L., Esko J., Giordano F.J., Huang Y., Gerber H.P., Ferrara N., and Johnson R.S. Loss of HIF-1α in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis. Cancer Cell 6 (2004) 485-495
    • (2004) Cancer Cell , vol.6 , pp. 485-495
    • Tang, N.1    Wang, L.2    Esko, J.3    Giordano, F.J.4    Huang, Y.5    Gerber, H.P.6    Ferrara, N.7    Johnson, R.S.8
  • 56
    • 0031020884 scopus 로고    scopus 로고
    • Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
    • Tian H., McKnight S.L., and Russell D.W. Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev. 11 (1997) 72-82
    • (1997) Genes Dev. , vol.11 , pp. 72-82
    • Tian, H.1    McKnight, S.L.2    Russell, D.W.3
  • 57
    • 0032213236 scopus 로고    scopus 로고
    • The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
    • Tian H., Hammer R.E., Matsumoto A.M., Russell D.W., and McKnight S.L. The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes Dev. 12 (1998) 3320-3324
    • (1998) Genes Dev. , vol.12 , pp. 3320-3324
    • Tian, H.1    Hammer, R.E.2    Matsumoto, A.M.3    Russell, D.W.4    McKnight, S.L.5
  • 58
    • 17144416530 scopus 로고    scopus 로고
    • Differential gene up-regulation by hypoxia-inducible factor-1α and hypoxia-inducible factor-2α in HEK293T cells
    • Wang V., Davis D.A., Haque M., Huang L.E., and Yarchoan R. Differential gene up-regulation by hypoxia-inducible factor-1α and hypoxia-inducible factor-2α in HEK293T cells. Cancer Res. 65 (2005) 3299-3306
    • (2005) Cancer Res. , vol.65 , pp. 3299-3306
    • Wang, V.1    Davis, D.A.2    Haque, M.3    Huang, L.E.4    Yarchoan, R.5
  • 59
    • 0032953340 scopus 로고    scopus 로고
    • What guides early embryonic blood vessel formation?
    • Weinstein B.M. What guides early embryonic blood vessel formation?. Dev. Dyn. 215 (1999) 2-11
    • (1999) Dev. Dyn. , vol.215 , pp. 2-11
    • Weinstein, B.M.1
  • 60
    • 0035859692 scopus 로고    scopus 로고
    • HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation
    • Yu F., White S.B., Zhao Q., and Lee F.S. HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation. Proc. Natl. Acad. Sci. USA 98 (2001) 9630-9635
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9630-9635
    • Yu, F.1    White, S.B.2    Zhao, Q.3    Lee, F.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.