A Werner syndrome protein homolog affects C. elegans development, growth rate, life span and sensitivity to DNA damage by acting at a DNA damage checkpoint

Development

Volumn 131, Issue 11, 2004, Pages 2565-2575

  Lee, Se Jin ^a   Yook, Jong Sung ^a   Han, Sung Min ^a   Koo, Hyeon Sook ^a  

^a Yonsei University   (South Korea)

Author keywords

Aging; Checkpoint; Disease model; DNA damage; Werner syndrome

Indexed keywords

LIPOFUSCIN; RNA; WERNER SYNDROME PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY SIZE; CAENORHABDITIS ELEGANS; CELL CYCLE S PHASE; CELL NUCLEUS; CONTROLLED STUDY; DEVELOPMENT; DEVELOPMENTAL DISORDER; DNA DAMAGE; DNA REPLICATION; EMBRYO CELL; FREQUENCY ANALYSIS; GAMMA IRRADIATION; GENETIC MODEL; GERM CELL; GROWTH DISORDER; GROWTH RATE; HEAD; IMMUNOLOCALIZATION; LARVAL DEVELOPMENT; LIFESPAN; MEIOSIS; MORPHOLOGY; NONHUMAN; PHENOTYPE; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; SEQUENCE HOMOLOGY; TISSUE DEGENERATION; WERNER SYNDROME;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CLONING, MOLECULAR; DNA DAMAGE; DNA HELICASES; DNA REPLICATION; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM CELLS; HUMANS; LARVA; PHENOTYPE; RADIATION, IONIZING; RECQ HELICASES; RNA INTERFERENCE; S PHASE; SEQUENCE HOMOLOGY, AMINO ACID; WERNER SYNDROME;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 3042776333     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01136     Document Type: Article

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