-
1
-
-
27744517295
-
Recent findings in immunology give tuberculosis vaccines a new boost
-
Kaufmann S.H. Recent findings in immunology give tuberculosis vaccines a new boost. Trends Immunol 26 (2005) 660-667
-
(2005)
Trends Immunol
, vol.26
, pp. 660-667
-
-
Kaufmann, S.H.1
-
2
-
-
32944466277
-
The development and impact of tuberculosis vaccines
-
Young D., and Dye C. The development and impact of tuberculosis vaccines. Cell 124 (2006) 683-687
-
(2006)
Cell
, vol.124
, pp. 683-687
-
-
Young, D.1
Dye, C.2
-
3
-
-
29044431543
-
Decreased survival of guinea pigs infected with Mycobacterium tuberculosis after multiple BCG vaccinations
-
Basaraba R.J., Izzo A.A., Brandt L., and Orme I.M. Decreased survival of guinea pigs infected with Mycobacterium tuberculosis after multiple BCG vaccinations. Vaccine 24 (2006) 280-286
-
(2006)
Vaccine
, vol.24
, pp. 280-286
-
-
Basaraba, R.J.1
Izzo, A.A.2
Brandt, L.3
Orme, I.M.4
-
5
-
-
20444448766
-
Live attenuated mutants of Mycobacterium tuberculosis as candidate vaccines against tuberculosis
-
Sambandamurthy V.K., and Jacobs Jr. W.R. Live attenuated mutants of Mycobacterium tuberculosis as candidate vaccines against tuberculosis. Microbes Infect 7 (2005) 955-961
-
(2005)
Microbes Infect
, vol.7
, pp. 955-961
-
-
Sambandamurthy, V.K.1
Jacobs Jr., W.R.2
-
6
-
-
21044444574
-
New live mycobacterial vaccines: the Geneva consensus on essential steps towards clinical development
-
Kamath A.T., Fruth U., Brennan M.J., Dobbelaer R., Hubrechts P., Ho M.M., Mayner R.E., Thole J., Walker K.B., Liu M., et al. New live mycobacterial vaccines: the Geneva consensus on essential steps towards clinical development. Vaccine 23 (2005) 3753-3761
-
(2005)
Vaccine
, vol.23
, pp. 3753-3761
-
-
Kamath, A.T.1
Fruth, U.2
Brennan, M.J.3
Dobbelaer, R.4
Hubrechts, P.5
Ho, M.M.6
Mayner, R.E.7
Thole, J.8
Walker, K.B.9
Liu, M.10
-
7
-
-
1642475493
-
Prospects for new TB vaccines: stop TB working group on TB vaccine development
-
Fruth U., and Young D. Prospects for new TB vaccines: stop TB working group on TB vaccine development. Int J Tuberc Lung Dis 8 (2004) 151-155
-
(2004)
Int J Tuberc Lung Dis
, vol.8
, pp. 151-155
-
-
Fruth, U.1
Young, D.2
-
8
-
-
20444443800
-
Recombinant BCG expressing Mycobacterium tuberculosis major extracellular proteins
-
Horwitz M.A. Recombinant BCG expressing Mycobacterium tuberculosis major extracellular proteins. Microbes Infect 7 (2005) 947-954
-
(2005)
Microbes Infect
, vol.7
, pp. 947-954
-
-
Horwitz, M.A.1
-
9
-
-
0037378874
-
A new vaccine against tuberculosis affords greater survival after challenge than the current vaccine in the guinea pig model of pulmonary tuberculosis
-
Horwitz M.A., and Harth G. A new vaccine against tuberculosis affords greater survival after challenge than the current vaccine in the guinea pig model of pulmonary tuberculosis. Infect Immun 71 (2003) 1672-1679
-
(2003)
Infect Immun
, vol.71
, pp. 1672-1679
-
-
Horwitz, M.A.1
Harth, G.2
-
10
-
-
22344433382
-
Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin
-
The authors equipped an urease C-deficient BCG with the membrane-perforating listeriolysin of Listeria monocytogenes. This recombinant BCG shows improved protection against M. tuberculosis, including a hypervirulent strain of the 'Beijing/W' family. Listeriolysin not only promotes antigen translocation into the cytoplasm but also apoptosis of infected macrophages, which leads to crosspresentation of mycobacterial antigens and subsequently enhanced T cell-mediated immunity.
-
Grode L., Seiler P., Baumann S., Hess J., Brinkmann V., Eddine A.N., Mann P., Goosmann C., Bandermann S., Smith D., et al. Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin. J Clin Invest 115 (2005) 2472-2479. The authors equipped an urease C-deficient BCG with the membrane-perforating listeriolysin of Listeria monocytogenes. This recombinant BCG shows improved protection against M. tuberculosis, including a hypervirulent strain of the 'Beijing/W' family. Listeriolysin not only promotes antigen translocation into the cytoplasm but also apoptosis of infected macrophages, which leads to crosspresentation of mycobacterial antigens and subsequently enhanced T cell-mediated immunity.
-
(2005)
J Clin Invest
, vol.115
, pp. 2472-2479
-
-
Grode, L.1
Seiler, P.2
Baumann, S.3
Hess, J.4
Brinkmann, V.5
Eddine, A.N.6
Mann, P.7
Goosmann, C.8
Bandermann, S.9
Smith, D.10
-
11
-
-
0037222145
-
Mapping of murine Th1 helper T-Cell epitopes of mycolyl transferases Ag85A, Ag85B, and Ag85C from Mycobacterium tuberculosis
-
D'Souza S., Rosseels V., Romano M., Tanghe A., Denis O., Jurion F., Castiglione N., Vanonckelen A., Palfliet K., and Huygen K. Mapping of murine Th1 helper T-Cell epitopes of mycolyl transferases Ag85A, Ag85B, and Ag85C from Mycobacterium tuberculosis. Infect Immun 71 (2003) 483-493
-
(2003)
Infect Immun
, vol.71
, pp. 483-493
-
-
D'Souza, S.1
Rosseels, V.2
Romano, M.3
Tanghe, A.4
Denis, O.5
Jurion, F.6
Castiglione, N.7
Vanonckelen, A.8
Palfliet, K.9
Huygen, K.10
-
12
-
-
0034610299
-
Recombinant bacillus calmette-guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model
-
Horwitz M.A., Harth G., Dillon B.J., and Maslesa-Galic S. Recombinant bacillus calmette-guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model. Proc Natl Acad Sci USA 97 (2000) 13853-13858
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13853-13858
-
-
Horwitz, M.A.1
Harth, G.2
Dillon, B.J.3
Maslesa-Galic, S.4
-
13
-
-
0038180875
-
Prospects for a better vaccine against tuberculosis
-
Reed S.G., Alderson M.R., Dalemans W., Lobet Y., and Skeiky Y.A. Prospects for a better vaccine against tuberculosis. Tuberculosis (Edinb) 83 (2003) 213-219
-
(2003)
Tuberculosis (Edinb)
, vol.83
, pp. 213-219
-
-
Reed, S.G.1
Alderson, M.R.2
Dalemans, W.3
Lobet, Y.4
Skeiky, Y.A.5
-
14
-
-
0032574807
-
Mycobacterium bovis bacille Calmette-Guerin strains secreting listeriolysin of Listeria monocytogenes
-
Hess J., Miko D., Catic A., Lehmensiek V., Russell D.G., and Kaufmann S.H. Mycobacterium bovis bacille Calmette-Guerin strains secreting listeriolysin of Listeria monocytogenes. Proc Natl Acad Sci USA 95 (1998) 5299-5304
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5299-5304
-
-
Hess, J.1
Miko, D.2
Catic, A.3
Lehmensiek, V.4
Russell, D.G.5
Kaufmann, S.H.6
-
15
-
-
0037128936
-
The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells
-
Glomski I.J., Gedde M.M., Tsang A.W., Swanson J.A., and Portnoy D.A. The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells. J Cell Biol 156 (2002) 1029-1038
-
(2002)
J Cell Biol
, vol.156
, pp. 1029-1038
-
-
Glomski, I.J.1
Gedde, M.M.2
Tsang, A.W.3
Swanson, J.A.4
Portnoy, D.A.5
-
16
-
-
0036686907
-
Worldwide occurrence of Beijing/W strains of Mycobacterium tuberculosis: a systematic review
-
Glynn J.R., Whiteley J., Bifani P.J., Kremer K., and van Soolingen D. Worldwide occurrence of Beijing/W strains of Mycobacterium tuberculosis: a systematic review. Emerg Infect Dis 8 (2002) 843-849
-
(2002)
Emerg Infect Dis
, vol.8
, pp. 843-849
-
-
Glynn, J.R.1
Whiteley, J.2
Bifani, P.J.3
Kremer, K.4
van Soolingen, D.5
-
17
-
-
18744372982
-
Improvement of differentiation and interpretability of spoligotyping for Mycobacterium tuberculosis complex isolates by introduction of new spacer oligonucleotides
-
van der Zanden A.G.M., Kremer K., Schouls L.M., Caimi K., Cataldi A., Hulleman A., Nagelkerke N.J.D., and van Soolingen D. Improvement of differentiation and interpretability of spoligotyping for Mycobacterium tuberculosis complex isolates by introduction of new spacer oligonucleotides. J Clin Microbiol 40 (2002) 4628-4639
-
(2002)
J Clin Microbiol
, vol.40
, pp. 4628-4639
-
-
van der Zanden, A.G.M.1
Kremer, K.2
Schouls, L.M.3
Caimi, K.4
Cataldi, A.5
Hulleman, A.6
Nagelkerke, N.J.D.7
van Soolingen, D.8
-
18
-
-
26444531050
-
Rational vaccine development - a new trend in tuberculosis control
-
Kaplan G. Rational vaccine development - a new trend in tuberculosis control. N Engl J Med 353 (2005) 1624-1625
-
(2005)
N Engl J Med
, vol.353
, pp. 1624-1625
-
-
Kaplan, G.1
-
19
-
-
0027462422
-
Immunity to intracellular bacteria
-
Kaufmann S.H. Immunity to intracellular bacteria. Annu Rev Immunol 11 (1993) 129-163
-
(1993)
Annu Rev Immunol
, vol.11
, pp. 129-163
-
-
Kaufmann, S.H.1
-
20
-
-
30444457915
-
Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis
-
+ T cells in vivo and induces protection against M. tuberculosis infection. These apoptotic vesicles display potent adjuvant activity by stimulating through Toll-like receptors.
-
+ T cells in vivo and induces protection against M. tuberculosis infection. These apoptotic vesicles display potent adjuvant activity by stimulating through Toll-like receptors.
-
(2006)
Immunity
, vol.24
, pp. 105-117
-
-
Winau, F.1
Weber, S.2
Sad, S.3
de Diego, J.4
Hoops, S.L.5
Breiden, B.6
Sandhoff, K.7
Brinkmann, V.8
Kaufmann, S.H.9
Schaible, U.E.10
-
21
-
-
0030070367
-
Listeria monocytogenes induces apoptosis of infected hepatocytes
-
Rogers H.W., Callery M.P., Deck B., and Unanue E.R. Listeria monocytogenes induces apoptosis of infected hepatocytes. J Immunol 156 (1996) 679-684
-
(1996)
J Immunol
, vol.156
, pp. 679-684
-
-
Rogers, H.W.1
Callery, M.P.2
Deck, B.3
Unanue, E.R.4
-
22
-
-
0034913656
-
TB vaccines: progress and problems
-
Andersen P. TB vaccines: progress and problems. Trends Immunol 22 (2001) 160-168
-
(2001)
Trends Immunol
, vol.22
, pp. 160-168
-
-
Andersen, P.1
-
23
-
-
0029148767
-
Characteristics of protective immunity engendered by vaccination of mice with purified culture filtrate protein antigens of Mycobacterium tuberculosis
-
Roberts A.D., Sonnenberg M.G., Ordway D.J., Furney S.K., Brennan P.J., Belisle J.T., and Orme I.M. Characteristics of protective immunity engendered by vaccination of mice with purified culture filtrate protein antigens of Mycobacterium tuberculosis. Immunology 85 (1995) 502-508
-
(1995)
Immunology
, vol.85
, pp. 502-508
-
-
Roberts, A.D.1
Sonnenberg, M.G.2
Ordway, D.J.3
Furney, S.K.4
Brennan, P.J.5
Belisle, J.T.6
Orme, I.M.7
-
24
-
-
15944388936
-
Boosting BCG with MVA85A: the first candidate subunit vaccine for tuberculosis in clinical trials
-
McShane H., Pathan A.A., Sander C.R., Goonetilleke N.P., Fletcher H.A., and Hill A.V. Boosting BCG with MVA85A: the first candidate subunit vaccine for tuberculosis in clinical trials. Tuberculosis (Edinb) 85 (2005) 47-52
-
(2005)
Tuberculosis (Edinb)
, vol.85
, pp. 47-52
-
-
McShane, H.1
Pathan, A.A.2
Sander, C.R.3
Goonetilleke, N.P.4
Fletcher, H.A.5
Hill, A.V.6
-
25
-
-
9144267735
-
Recombinant modified vaccinia virus ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans
-
McShane H., Pathan A.A., Sander C.R., Keating S.M., Gilbert S.C., Huygen K., Fletcher H.A., and Hill A.V. Recombinant modified vaccinia virus ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans. Nat Med 10 (2004) 1240-1244
-
(2004)
Nat Med
, vol.10
, pp. 1240-1244
-
-
McShane, H.1
Pathan, A.A.2
Sander, C.R.3
Keating, S.M.4
Gilbert, S.C.5
Huygen, K.6
Fletcher, H.A.7
Hill, A.V.8
-
26
-
-
0042346025
-
Enhanced immunogenicity and protective efficacy against Mycobacterium tuberculosis of bacille Calmette-Guerin vaccine using mucosal administration and boosting with a recombinant modified vaccinia virus ankara
-
Goonetilleke N.P., McShane H., Hannan C.M., Anderson R.J., Brookes R.H., and Hill A.V. Enhanced immunogenicity and protective efficacy against Mycobacterium tuberculosis of bacille Calmette-Guerin vaccine using mucosal administration and boosting with a recombinant modified vaccinia virus ankara. J Immunol 171 (2003) 1602-1609
-
(2003)
J Immunol
, vol.171
, pp. 1602-1609
-
-
Goonetilleke, N.P.1
McShane, H.2
Hannan, C.M.3
Anderson, R.J.4
Brookes, R.H.5
Hill, A.V.6
-
27
-
-
2942705762
-
Developing an improved vaccine against tuberculosis
-
McShane H. Developing an improved vaccine against tuberculosis. Expert Rev Vaccines 3 (2004) 299-306
-
(2004)
Expert Rev Vaccines
, vol.3
, pp. 299-306
-
-
McShane, H.1
-
28
-
-
23344440201
-
Enhancing the protective efficacy of Mycobacterium bovis BCG vaccination against tuberculosis by boosting with the Mycobacterium tuberculosis major secretory protein
-
Horwitz M.A., Harth G., Dillon B.J., and Maslesa-Galic S. Enhancing the protective efficacy of Mycobacterium bovis BCG vaccination against tuberculosis by boosting with the Mycobacterium tuberculosis major secretory protein. Infect Immun 73 (2005) 4676-4683
-
(2005)
Infect Immun
, vol.73
, pp. 4676-4683
-
-
Horwitz, M.A.1
Harth, G.2
Dillon, B.J.3
Maslesa-Galic, S.4
-
29
-
-
20144362100
-
Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6
-
Langermans J.A., Doherty T.M., Vervenne R.A., van der Laan T., Lyashchenko K., Greenwald R., Agger E.M., Aagaard C., Weiler H., van Soolingen D., et al. Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6. Vaccine 23 (2005) 2740-2750
-
(2005)
Vaccine
, vol.23
, pp. 2740-2750
-
-
Langermans, J.A.1
Doherty, T.M.2
Vervenne, R.A.3
van der Laan, T.4
Lyashchenko, K.5
Greenwald, R.6
Agger, E.M.7
Aagaard, C.8
Weiler, H.9
van Soolingen, D.10
-
30
-
-
4644235020
-
Protective effect of a tuberculosis subunit vaccine based on a fusion of antigen 85B and ESAT-6 in the aerosol guinea pig model
-
Olsen A.W., Williams A., Okkels L.M., Hatch G., and Andersen P. Protective effect of a tuberculosis subunit vaccine based on a fusion of antigen 85B and ESAT-6 in the aerosol guinea pig model. Infect Immun 72 (2004) 6148-6150
-
(2004)
Infect Immun
, vol.72
, pp. 6148-6150
-
-
Olsen, A.W.1
Williams, A.2
Okkels, L.M.3
Hatch, G.4
Andersen, P.5
-
31
-
-
10444225931
-
Comparative analysis of different vaccine constructs expressing defined antigens from Mycobacterium tuberculosis
-
Doherty T.M., Olsen A.W., Weischenfeldt J., Huygen K., D'Souza S., Kondratieva T.K., Yeremeev V.V., Apt A.S., Raupach B., Grode L., et al. Comparative analysis of different vaccine constructs expressing defined antigens from Mycobacterium tuberculosis. J Infect Dis 190 (2004) 2146-2153
-
(2004)
J Infect Dis
, vol.190
, pp. 2146-2153
-
-
Doherty, T.M.1
Olsen, A.W.2
Weischenfeldt, J.3
Huygen, K.4
D'Souza, S.5
Kondratieva, T.K.6
Yeremeev, V.V.7
Apt, A.S.8
Raupach, B.9
Grode, L.10
-
32
-
-
0037019865
-
Poly-L-arginine synergizes with oligodeoxynucleotides containing CpG-motifs (CpG-ODN) for enhanced and prolonged immune responses and prevents the CpG-ODN-induced systemic release of pro-inflammatory cytokines
-
Lingnau K., Egyed A., Schellack C., Mattner F., Buschle M., and Schmidt W. Poly-L-arginine synergizes with oligodeoxynucleotides containing CpG-motifs (CpG-ODN) for enhanced and prolonged immune responses and prevents the CpG-ODN-induced systemic release of pro-inflammatory cytokines. Vaccine 20 (2002) 3498-3508
-
(2002)
Vaccine
, vol.20
, pp. 3498-3508
-
-
Lingnau, K.1
Egyed, A.2
Schellack, C.3
Mattner, F.4
Buschle, M.5
Schmidt, W.6
-
33
-
-
0037992894
-
Mutants of the Escherichia coli heat-labile enterotoxin as safe and strong adjuvants for intranasal delivery of vaccines
-
Peppoloni S., Ruggiero P., Contorni M., Morandi M., Pizza M., Rappuoli R., Podda A., and Del Giudice G. Mutants of the Escherichia coli heat-labile enterotoxin as safe and strong adjuvants for intranasal delivery of vaccines. Expert Rev Vaccines 2 (2003) 285-293
-
(2003)
Expert Rev Vaccines
, vol.2
, pp. 285-293
-
-
Peppoloni, S.1
Ruggiero, P.2
Contorni, M.3
Morandi, M.4
Pizza, M.5
Rappuoli, R.6
Podda, A.7
Del Giudice, G.8
-
34
-
-
28344445877
-
Preclinical testing of new vaccines for tuberculosis: a comprehensive review
-
Orme I.M. Preclinical testing of new vaccines for tuberculosis: a comprehensive review. Vaccine 24 (2006) 2-19
-
(2006)
Vaccine
, vol.24
, pp. 2-19
-
-
Orme, I.M.1
-
35
-
-
7044235500
-
The protective effect of the Mycobacterium bovis BCG vaccine is increased by coadministration with the Mycobacterium tuberculosis 72-kilodalton fusion polyprotein Mtb72F in M. tuberculosis-infected guinea pigs
-
Brandt L., Skeiky Y.A., Alderson M.R., Lobet Y., Dalemans W., Turner O.C., Basaraba R.J., Izzo A.A., Lasco T.M., Chapman P.L., et al. The protective effect of the Mycobacterium bovis BCG vaccine is increased by coadministration with the Mycobacterium tuberculosis 72-kilodalton fusion polyprotein Mtb72F in M. tuberculosis-infected guinea pigs. Infect Immun 72 (2004) 6622-6632
-
(2004)
Infect Immun
, vol.72
, pp. 6622-6632
-
-
Brandt, L.1
Skeiky, Y.A.2
Alderson, M.R.3
Lobet, Y.4
Dalemans, W.5
Turner, O.C.6
Basaraba, R.J.7
Izzo, A.A.8
Lasco, T.M.9
Chapman, P.L.10
-
36
-
-
33645517291
-
Evaluation of the Mtb72F polyprotein vaccine in a rabbit model of tuberculous meningitis
-
Tsenova L., Harbacheuski R., Moreira A.L., Ellison E., Dalemans W., Alderson M.R., Mathema B., Reed S.G., Skeiky Y.A., and Kaplan G. Evaluation of the Mtb72F polyprotein vaccine in a rabbit model of tuberculous meningitis. Infect Immun 74 (2006) 2392-2401
-
(2006)
Infect Immun
, vol.74
, pp. 2392-2401
-
-
Tsenova, L.1
Harbacheuski, R.2
Moreira, A.L.3
Ellison, E.4
Dalemans, W.5
Alderson, M.R.6
Mathema, B.7
Reed, S.G.8
Skeiky, Y.A.9
Kaplan, G.10
-
37
-
-
0031020339
-
Adjuvant modulation of immune responses to tuberculosis subunit vaccines
-
Lindblad E.B., Elhay M.J., Silva R., Appelberg R., and Andersen P. Adjuvant modulation of immune responses to tuberculosis subunit vaccines. Infect Immun 65 (1997) 623-629
-
(1997)
Infect Immun
, vol.65
, pp. 623-629
-
-
Lindblad, E.B.1
Elhay, M.J.2
Silva, R.3
Appelberg, R.4
Andersen, P.5
-
38
-
-
0036494274
-
Vaccination with poly-L-arginine as immunostimulant for peptide vaccines: induction of potent and long-lasting T-cell responses against cancer antigens
-
Mattner F., Fleitmann J.K., Lingnau K., Schmidt W., Egyed A., Fritz J., Zauner W., Wittmann B., Gorny I., Berger M., et al. Vaccination with poly-L-arginine as immunostimulant for peptide vaccines: induction of potent and long-lasting T-cell responses against cancer antigens. Cancer Res 62 (2002) 1477-1480
-
(2002)
Cancer Res
, vol.62
, pp. 1477-1480
-
-
Mattner, F.1
Fleitmann, J.K.2
Lingnau, K.3
Schmidt, W.4
Egyed, A.5
Fritz, J.6
Zauner, W.7
Wittmann, B.8
Gorny, I.9
Berger, M.10
-
39
-
-
4043049496
-
The artificial antimicrobial peptide KLKLLLLLKLK induces predominantly a TH2-type immune response to co-injected antigens
-
Fritz J.H., Brunner S., Birnstiel M.L., Buschle M., Gabain A., Mattner F., and Zauner W. The artificial antimicrobial peptide KLKLLLLLKLK induces predominantly a TH2-type immune response to co-injected antigens. Vaccine 22 (2004) 3274-3284
-
(2004)
Vaccine
, vol.22
, pp. 3274-3284
-
-
Fritz, J.H.1
Brunner, S.2
Birnstiel, M.L.3
Buschle, M.4
Gabain, A.5
Mattner, F.6
Zauner, W.7
-
41
-
-
2942596008
-
Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein
-
Skeiky Y.A., Alderson M.R., Ovendale P.J., Guderian J.A., Brandt L., Dillon D.C., Campos-Neto A., Lobet Y., Dalemans W., Orme I.M., et al. Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein. J Immunol 172 (2004) 7618-7628
-
(2004)
J Immunol
, vol.172
, pp. 7618-7628
-
-
Skeiky, Y.A.1
Alderson, M.R.2
Ovendale, P.J.3
Guderian, J.A.4
Brandt, L.5
Dillon, D.C.6
Campos-Neto, A.7
Lobet, Y.8
Dalemans, W.9
Orme, I.M.10
-
42
-
-
20044385066
-
Novel recombinant BCG and DNA-vaccination against tuberculosis in a cynomolgus monkey model
-
Kita Y., Tanaka T., Yoshida S., Ohara N., Kaneda Y., Kuwayama S., Muraki Y., Kanamaru N., Hashimoto S., Takai H., et al. Novel recombinant BCG and DNA-vaccination against tuberculosis in a cynomolgus monkey model. Vaccine 23 (2005) 2132-2135
-
(2005)
Vaccine
, vol.23
, pp. 2132-2135
-
-
Kita, Y.1
Tanaka, T.2
Yoshida, S.3
Ohara, N.4
Kaneda, Y.5
Kuwayama, S.6
Muraki, Y.7
Kanamaru, N.8
Hashimoto, S.9
Takai, H.10
-
43
-
-
1342324771
-
Cutting edge: a new approach to modeling early lung immunity in murine tuberculosis
-
Bhatt K., Hickman S.P., and Salgame P. Cutting edge: a new approach to modeling early lung immunity in murine tuberculosis. J Immunol 172 (2004) 2748-2751
-
(2004)
J Immunol
, vol.172
, pp. 2748-2751
-
-
Bhatt, K.1
Hickman, S.P.2
Salgame, P.3
-
44
-
-
33645109281
-
A role for CD4CD25 T cells in regulation of the immune response during human tuberculosis
-
Ribeiro-Rodrigues R., Resende Co T., Rojas R., Toossi Z., Dietze R., Boom W.H., Maciel E., and Hirsch C.S. A role for CD4CD25 T cells in regulation of the immune response during human tuberculosis. Clin Exp Immunol 144 (2006) 25-34
-
(2006)
Clin Exp Immunol
, vol.144
, pp. 25-34
-
-
Ribeiro-Rodrigues, R.1
Resende Co, T.2
Rojas, R.3
Toossi, Z.4
Dietze, R.5
Boom, W.H.6
Maciel, E.7
Hirsch, C.S.8
-
45
-
-
2942720565
-
Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development
-
Smits H.H., van Beelen A.J., Hessle C., Westland R., de Jong E., Soeteman E., Wold A., Wierenga E.A., and Kapsenberg M.L. Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development. Eur J Immunol 34 (2004) 1371-1380
-
(2004)
Eur J Immunol
, vol.34
, pp. 1371-1380
-
-
Smits, H.H.1
van Beelen, A.J.2
Hessle, C.3
Westland, R.4
de Jong, E.5
Soeteman, E.6
Wold, A.7
Wierenga, E.A.8
Kapsenberg, M.L.9
-
46
-
-
23944489407
-
Selected toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
-
Napolitani G., Rinaldi A., Bertoni F., Sallusto F., and Lanzavecchia A. Selected toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat Immunol 6 (2005) 769-776
-
(2005)
Nat Immunol
, vol.6
, pp. 769-776
-
-
Napolitani, G.1
Rinaldi, A.2
Bertoni, F.3
Sallusto, F.4
Lanzavecchia, A.5
-
48
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
+ T cells into Th cells that produce IL-17 are examined, characterizing this unique Th lineage that regulates tissue inflammation and has been linked to autoimmune diseases. This cytokine could be involved in immunity to pulmonary tuberculosis.
-
+ T cells into Th cells that produce IL-17 are examined, characterizing this unique Th lineage that regulates tissue inflammation and has been linked to autoimmune diseases. This cytokine could be involved in immunity to pulmonary tuberculosis.
-
(2005)
Nat Immunol
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
-
49
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington L.E., Hatton R.D., Mangan P.R., Turner H., Murphy T.L., Murphy K.M., and Weaver C.T. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6 (2005) 1123-1132
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
50
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish C.L., Chen Y., Blumenschein W.M., Mattson J., Basham B., Sedgwick J.D., McClanahan T., Kastelein R.A., and Cua D.J. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 201 (2005) 233-240
-
(2005)
J Exp Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
51
-
-
0242350932
-
Early granuloma formation after aerosol Mycobacterium tuberculosis infection is regulated by neutrophils via CXCR3-signaling chemokines
-
Seiler P., Aichele P., Bandermann S., Hauser A.E., Lu B., Gerard N.P., Gerard C., Ehlers S., Mollenkopf H.J., and Kaufmann S.H. Early granuloma formation after aerosol Mycobacterium tuberculosis infection is regulated by neutrophils via CXCR3-signaling chemokines. Eur J Immunol 33 (2003) 2676-2686
-
(2003)
Eur J Immunol
, vol.33
, pp. 2676-2686
-
-
Seiler, P.1
Aichele, P.2
Bandermann, S.3
Hauser, A.E.4
Lu, B.5
Gerard, N.P.6
Gerard, C.7
Ehlers, S.8
Mollenkopf, H.J.9
Kaufmann, S.H.10
-
52
-
-
4544371275
-
Mycobacterium tuberculosis triggers apoptosis in peripheral neutrophils involving toll-like receptor 2 and p38 mitogen protein kinase in tuberculosis patients
-
Aleman M., Schierloh P., de la Barrera S.S., Musella R.M., Saab M.A., Baldini M., Abbate E., and Sasiain M.C. Mycobacterium tuberculosis triggers apoptosis in peripheral neutrophils involving toll-like receptor 2 and p38 mitogen protein kinase in tuberculosis patients. Infect Immun 72 (2004) 5150-5158
-
(2004)
Infect Immun
, vol.72
, pp. 5150-5158
-
-
Aleman, M.1
Schierloh, P.2
de la Barrera, S.S.3
Musella, R.M.4
Saab, M.A.5
Baldini, M.6
Abbate, E.7
Sasiain, M.C.8
-
53
-
-
0033958803
-
Neutrophils play a protective nonphagocytic role in systemic Mycobacterium tuberculosis infection of mice
-
Pedrosa J., Saunders B.M., Appelberg R., Orme I.M., Silva M.T., and Cooper A.M. Neutrophils play a protective nonphagocytic role in systemic Mycobacterium tuberculosis infection of mice. Infect Immun 68 (2000) 577-583
-
(2000)
Infect Immun
, vol.68
, pp. 577-583
-
-
Pedrosa, J.1
Saunders, B.M.2
Appelberg, R.3
Orme, I.M.4
Silva, M.T.5
Cooper, A.M.6
-
54
-
-
23944460617
-
Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs
-
Happel K.I., Lockhart E.A., Mason C.M., Porretta E., Keoshkerian E., Odden A.R., Nelson S., and Ramsay A.J. Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs. Infect Immun 73 (2005) 5782-5788
-
(2005)
Infect Immun
, vol.73
, pp. 5782-5788
-
-
Happel, K.I.1
Lockhart, E.A.2
Mason, C.M.3
Porretta, E.4
Keoshkerian, E.5
Odden, A.R.6
Nelson, S.7
Ramsay, A.J.8
-
55
-
-
29644444042
-
Plasmid interleukin-23 (IL-23), but not plasmid IL-27, enhances the protective efficacy of a DNA vaccine against Mycobacterium tuberculosis infection
-
Wozniak T.M., Ryan A.A., Triccas J.A., and Britton W.J. Plasmid interleukin-23 (IL-23), but not plasmid IL-27, enhances the protective efficacy of a DNA vaccine against Mycobacterium tuberculosis infection. Infect Immun 74 (2006) 557-565
-
(2006)
Infect Immun
, vol.74
, pp. 557-565
-
-
Wozniak, T.M.1
Ryan, A.A.2
Triccas, J.A.3
Britton, W.J.4
-
56
-
-
23244458100
-
IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available
-
Khader S.A., Pearl J.E., Sakamoto K., Gilmartin L., Bell G.K., Jelley-Gibbs D.M., Ghilardi N., deSauvage F., and Cooper A.M. IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available. J Immunol 175 (2005) 788-795
-
(2005)
J Immunol
, vol.175
, pp. 788-795
-
-
Khader, S.A.1
Pearl, J.E.2
Sakamoto, K.3
Gilmartin, L.4
Bell, G.K.5
Jelley-Gibbs, D.M.6
Ghilardi, N.7
deSauvage, F.8
Cooper, A.M.9
-
57
-
-
17644388063
-
Annulling a dangerous liaison: vaccination strategies against AIDS and tuberculosis
-
Kaufmann S.H.E., and McMichael A.J. Annulling a dangerous liaison: vaccination strategies against AIDS and tuberculosis. Nat Med 11 (2005) S33-S44
-
(2005)
Nat Med
, vol.11
-
-
Kaufmann, S.H.E.1
McMichael, A.J.2
-
58
-
-
23944440975
-
No life without death-apoptosis as prerequisite for T cell activation
-
Winau F., Hegasy G., Kaufmann S.H., and Schaible U.E. No life without death-apoptosis as prerequisite for T cell activation. Apoptosis 10 (2005) 707-715
-
(2005)
Apoptosis
, vol.10
, pp. 707-715
-
-
Winau, F.1
Hegasy, G.2
Kaufmann, S.H.3
Schaible, U.E.4
-
59
-
-
0041965927
-
Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis
-
Schaible U.E., Winau F., Sieling P.A., Fischer K., Collins H.L., Hagens K., Modlin R.L., Brinkmann V., and Kaufmann S.H. Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis. Nat Med 9 (2003) 1039-1046
-
(2003)
Nat Med
, vol.9
, pp. 1039-1046
-
-
Schaible, U.E.1
Winau, F.2
Sieling, P.A.3
Fischer, K.4
Collins, H.L.5
Hagens, K.6
Modlin, R.L.7
Brinkmann, V.8
Kaufmann, S.H.9
-
61
-
-
0037141105
-
+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo
-
+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo. J Exp Med 195 (2002) 1289-1302
-
(2002)
J Exp Med
, vol.195
, pp. 1289-1302
-
-
Iyoda, T.1
Shimoyama, S.2
Liu, K.3
Omatsu, Y.4
Akiyama, Y.5
Maeda, Y.6
Takahara, K.7
Steinman, R.M.8
Inaba, K.9
-
62
-
-
0035963379
-
Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction
-
Ochsenbein A.F., Sierro S., Odermatt B., Pericin M., Karrer U., Hermans J., Hemmi S., Hengartner H., and Zinkernagel R.M. Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction. Nature 411 (2001) 1058-1064
-
(2001)
Nature
, vol.411
, pp. 1058-1064
-
-
Ochsenbein, A.F.1
Sierro, S.2
Odermatt, B.3
Pericin, M.4
Karrer, U.5
Hermans, J.6
Hemmi, S.7
Hengartner, H.8
Zinkernagel, R.M.9
-
63
-
-
0344392246
-
Endogenous neosynthesis vs. cross-presentation of viral antigens for cytotoxic T cell priming
-
Freigang S., Egger D., Bienz K., Hengartner H., and Zinkernagel R.M. Endogenous neosynthesis vs. cross-presentation of viral antigens for cytotoxic T cell priming. Proc Natl Acad Sci USA 100 (2003) 13477-13482
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 13477-13482
-
-
Freigang, S.1
Egger, D.2
Bienz, K.3
Hengartner, H.4
Zinkernagel, R.M.5
-
64
-
-
0036737779
-
On cross-priming of MHC class I-specific CTL: rule or exception?
-
Zinkernagel R.M. On cross-priming of MHC class I-specific CTL: rule or exception?. Eur J Immunol 32 (2002) 2385-2392
-
(2002)
Eur J Immunol
, vol.32
, pp. 2385-2392
-
-
Zinkernagel, R.M.1
-
65
-
-
3543060047
-
Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients
-
Thomas A.M., Santarsiero L.M., Lutz E.R., Armstrong T.D., Chen Y.C., Huang L.Q., Laheru D.A., Goggins M., Hruban R.H., and Jaffee E.M. Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients. J Exp Med 200 (2004) 297-306
-
(2004)
J Exp Med
, vol.200
, pp. 297-306
-
-
Thomas, A.M.1
Santarsiero, L.M.2
Lutz, E.R.3
Armstrong, T.D.4
Chen, Y.C.5
Huang, L.Q.6
Laheru, D.A.7
Goggins, M.8
Hruban, R.H.9
Jaffee, E.M.10
-
66
-
-
2442550745
-
Loading of MHC class I and II presentation pathways by exogenous antigens: a quantitative in vivo comparison
-
Storni T., and Bachmann M.F. Loading of MHC class I and II presentation pathways by exogenous antigens: a quantitative in vivo comparison. J Immunol 172 (2004) 6129-6135
-
(2004)
J Immunol
, vol.172
, pp. 6129-6135
-
-
Storni, T.1
Bachmann, M.F.2
-
67
-
-
0242331619
-
Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens
-
Ackerman A.L., Kyritsis C., Tampe R., and Cresswell P. Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens. Proc Natl Acad Sci USA 100 (2003) 12889-12894
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12889-12894
-
-
Ackerman, A.L.1
Kyritsis, C.2
Tampe, R.3
Cresswell, P.4
-
68
-
-
6344225314
-
Cross-presentation of Listeria-derived CD8 T cell epitopes requires unstable bacterial translation products
-
Janda J., Schoneberger P., Skoberne M., Messerle M., Russmann H., and Geginat G. Cross-presentation of Listeria-derived CD8 T cell epitopes requires unstable bacterial translation products. J Immunol 173 (2004) 5644-5651
-
(2004)
J Immunol
, vol.173
, pp. 5644-5651
-
-
Janda, J.1
Schoneberger, P.2
Skoberne, M.3
Messerle, M.4
Russmann, H.5
Geginat, G.6
-
69
-
-
0032485487
-
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
-
Albert M.L., Sauter B., and Bhardwaj N. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392 (1998) 86-89
-
(1998)
Nature
, vol.392
, pp. 86-89
-
-
Albert, M.L.1
Sauter, B.2
Bhardwaj, N.3
-
70
-
-
0034695889
-
Salmonella-induced apoptosis of infected macrophages results in presentation of a bacteria-encoded antigen after uptake by bystander dendritic cells
-
Yrlid U., and Wick M.J. Salmonella-induced apoptosis of infected macrophages results in presentation of a bacteria-encoded antigen after uptake by bystander dendritic cells. J Exp Med 191 (2000) 613-624
-
(2000)
J Exp Med
, vol.191
, pp. 613-624
-
-
Yrlid, U.1
Wick, M.J.2
-
71
-
-
0032724044
-
The induction of apoptosis by bacterial pathogens
-
Weinrauch Y., and Zychlinsky A. The induction of apoptosis by bacterial pathogens. Annu Rev Microbiol 53 (1999) 155-187
-
(1999)
Annu Rev Microbiol
, vol.53
, pp. 155-187
-
-
Weinrauch, Y.1
Zychlinsky, A.2
-
72
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner M.O. The biochemistry of apoptosis. Nature 407 (2000) 770-776
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
73
-
-
0034614897
-
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
-
Sauter B., Albert M.L., Francisco L., Larsson M., Somersan S., and Bhardwaj N. Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med 191 (2000) 423-434
-
(2000)
J Exp Med
, vol.191
, pp. 423-434
-
-
Sauter, B.1
Albert, M.L.2
Francisco, L.3
Larsson, M.4
Somersan, S.5
Bhardwaj, N.6
-
74
-
-
22744441633
-
Apoptotic cells deliver processed antigen to dendritic cells for cross-presentation
-
Blachere N.E., Darnell R.B., and Albert M.L. Apoptotic cells deliver processed antigen to dendritic cells for cross-presentation. PLoS Biol 3 (2005) e185
-
(2005)
PLoS Biol
, vol.3
-
-
Blachere, N.E.1
Darnell, R.B.2
Albert, M.L.3
-
75
-
-
30144435317
-
Virulent clinical isolates of Mycobacterium tuberculosis grow rapidly and induce cellular necrosis but minimal apoptosis in murine macrophages
-
Park J.S., Tamayo M.H., Gonzalez-Juarrero M., Orme I.M., and Ordway D.J. Virulent clinical isolates of Mycobacterium tuberculosis grow rapidly and induce cellular necrosis but minimal apoptosis in murine macrophages. J Leukoc Biol 79 (2006) 80-86
-
(2006)
J Leukoc Biol
, vol.79
, pp. 80-86
-
-
Park, J.S.1
Tamayo, M.H.2
Gonzalez-Juarrero, M.3
Orme, I.M.4
Ordway, D.J.5
-
76
-
-
33646027045
-
Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway
-
Lee J., Remold H.G., Ieong M.H., and Kornfeld H. Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway. J Immunol 176 (2006) 4267-4274
-
(2006)
J Immunol
, vol.176
, pp. 4267-4274
-
-
Lee, J.1
Remold, H.G.2
Ieong, M.H.3
Kornfeld, H.4
-
77
-
-
17144415540
-
Role of mycobacteria-induced monocyte/macrophage apoptosis in the pathogenesis of human tuberculosis
-
Bocchino M., Galati D., Sanduzzi A., Colizzi V., Brunetti E., and Mancino G. Role of mycobacteria-induced monocyte/macrophage apoptosis in the pathogenesis of human tuberculosis. Int J Tuberc Lung Dis 9 (2005) 375-383
-
(2005)
Int J Tuberc Lung Dis
, vol.9
, pp. 375-383
-
-
Bocchino, M.1
Galati, D.2
Sanduzzi, A.3
Colizzi, V.4
Brunetti, E.5
Mancino, G.6
-
78
-
-
0033812475
-
Building better vaccines: how apoptotic cell death can induce inflammation and activate innate and adaptive immunity
-
Restifo N.P. Building better vaccines: how apoptotic cell death can induce inflammation and activate innate and adaptive immunity. Curr Opin Immunol 12 (2000) 597-603
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 597-603
-
-
Restifo, N.P.1
-
79
-
-
1642553419
-
Monoclonal antibody therapeutics and apoptosis
-
Ludwig D.L., Pereira D.S., Zhu Z., Hicklin D.J., and Bohlen P. Monoclonal antibody therapeutics and apoptosis. Oncogene 22 (2003) 9097-9106
-
(2003)
Oncogene
, vol.22
, pp. 9097-9106
-
-
Ludwig, D.L.1
Pereira, D.S.2
Zhu, Z.3
Hicklin, D.J.4
Bohlen, P.5
-
80
-
-
0034425778
-
Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered Fas-mediated apoptosis
-
Chattergoon M.A., Kim J.J., Yang J.S., Robinson T.M., Lee D.J., Dentchev T., Wilson D.M., Ayyavoo V., and Weiner D.B. Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered Fas-mediated apoptosis. Nat Biotechnol 18 (2000) 974-979
-
(2000)
Nat Biotechnol
, vol.18
, pp. 974-979
-
-
Chattergoon, M.A.1
Kim, J.J.2
Yang, J.S.3
Robinson, T.M.4
Lee, D.J.5
Dentchev, T.6
Wilson, D.M.7
Ayyavoo, V.8
Weiner, D.B.9
-
81
-
-
0036086077
-
Immunomodulation by apoptosis-inducing caspases for an influenza DNA vaccine delivered by gene gun
-
Sasaki S., Xin K.Q., Okudela K., Okuda K., and Ishii N. Immunomodulation by apoptosis-inducing caspases for an influenza DNA vaccine delivered by gene gun. Gene Ther 9 (2002) 828-831
-
(2002)
Gene Ther
, vol.9
, pp. 828-831
-
-
Sasaki, S.1
Xin, K.Q.2
Okudela, K.3
Okuda, K.4
Ishii, N.5
-
82
-
-
0035006080
-
Apoptosis-mediated enhancement of DNA-raised immune responses by mutant caspases
-
Sasaki S., Amara R.R., Oran A.E., Smith J.M., and Robinson H.L. Apoptosis-mediated enhancement of DNA-raised immune responses by mutant caspases. Nat Biotechnol 19 (2001) 543-547
-
(2001)
Nat Biotechnol
, vol.19
, pp. 543-547
-
-
Sasaki, S.1
Amara, R.R.2
Oran, A.E.3
Smith, J.M.4
Robinson, H.L.5
-
83
-
-
0029997423
-
Delivery of macromolecules into cytosol using liposomes containing hemolysin from Listeria monocytogenes
-
Lee K.D., Oh Y.K., Portnoy D.A., and Swanson J.A. Delivery of macromolecules into cytosol using liposomes containing hemolysin from Listeria monocytogenes. J Biol Chem 271 (1996) 7249-7252
-
(1996)
J Biol Chem
, vol.271
, pp. 7249-7252
-
-
Lee, K.D.1
Oh, Y.K.2
Portnoy, D.A.3
Swanson, J.A.4
-
84
-
-
4544298326
-
A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response
-
Reed M.B., Domenech P., Manca C., Su H., Barczak A.K., Kreiswirth B.N., Kaplan G., and Barry III C.E. A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response. Nature 431 (2004) 84-87
-
(2004)
Nature
, vol.431
, pp. 84-87
-
-
Reed, M.B.1
Domenech, P.2
Manca, C.3
Su, H.4
Barczak, A.K.5
Kreiswirth, B.N.6
Kaplan, G.7
Barry III, C.E.8
-
85
-
-
1842788227
-
Stable association between strains of Mycobacterium tuberculosis and their human host populations
-
Hirsh A.E., Tsolaki A.G., DeRiemer K., Feldman M.W., and Small P.M. Stable association between strains of Mycobacterium tuberculosis and their human host populations. Proc Natl Acad Sci USA 101 (2004) 4871-4876
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4871-4876
-
-
Hirsh, A.E.1
Tsolaki, A.G.2
DeRiemer, K.3
Feldman, M.W.4
Small, P.M.5
-
86
-
-
16844369607
-
Natural regulatory T cells in infectious disease
-
Belkaid Y., and Rouse B.T. Natural regulatory T cells in infectious disease. Nat Immunol 6 (2005) 353-360
-
(2005)
Nat Immunol
, vol.6
, pp. 353-360
-
-
Belkaid, Y.1
Rouse, B.T.2
-
87
-
-
1642364976
-
Mini-review: regulatory T cells and infection: suppression revisited
-
Mittrucker H.W., and Kaufmann S.H. Mini-review: regulatory T cells and infection: suppression revisited. Eur J Immunol 34 (2004) 306-312
-
(2004)
Eur J Immunol
, vol.34
, pp. 306-312
-
-
Mittrucker, H.W.1
Kaufmann, S.H.2
-
88
-
-
33645276814
-
Regulatory T cells are expanded in blood and disease sites in tuberculosis patients
-
Guyot-Revol V., Innes J.A., Hackforth S., Hinks T., and Lalvani A. Regulatory T cells are expanded in blood and disease sites in tuberculosis patients. Am J Respir Crit Care Med 173 (2006) 803-810
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 803-810
-
-
Guyot-Revol, V.1
Innes, J.A.2
Hackforth, S.3
Hinks, T.4
Lalvani, A.5
-
89
-
-
11144358194
-
Down-modulation of lung immune responses by interleukin-10 and transforming growth factor beta (TGF-beta) and analysis of TGF-beta receptors I and II in active tuberculosis
-
Bonecini-Almeida M.G., Ho J.L., Boechat N., Huard R.C., Chitale S., Doo H., Geng J., Rego L., Lazzarini L.C., Kritski A.L., et al. Down-modulation of lung immune responses by interleukin-10 and transforming growth factor beta (TGF-beta) and analysis of TGF-beta receptors I and II in active tuberculosis. Infect Immun 72 (2004) 2628-2634
-
(2004)
Infect Immun
, vol.72
, pp. 2628-2634
-
-
Bonecini-Almeida, M.G.1
Ho, J.L.2
Boechat, N.3
Huard, R.C.4
Chitale, S.5
Doo, H.6
Geng, J.7
Rego, L.8
Lazzarini, L.C.9
Kritski, A.L.10
-
90
-
-
1342302571
-
Effect of neutralizing transforming growth factor beta1 on the immune response against Mycobacterium tuberculosis in guinea pigs
-
Allen S.S., Cassone L., Lasco T.M., and McMurray D.N. Effect of neutralizing transforming growth factor beta1 on the immune response against Mycobacterium tuberculosis in guinea pigs. Infect Immun 72 (2004) 1358-1363
-
(2004)
Infect Immun
, vol.72
, pp. 1358-1363
-
-
Allen, S.S.1
Cassone, L.2
Lasco, T.M.3
McMurray, D.N.4
-
91
-
-
0035495579
-
How can immunology contribute to the control of tuberculosis?
-
Kaufmann S.H. How can immunology contribute to the control of tuberculosis?. Nat Rev Immunol 1 (2001) 20-30
-
(2001)
Nat Rev Immunol
, vol.1
, pp. 20-30
-
-
Kaufmann, S.H.1
-
92
-
-
0347511897
-
Stable T-cell population expressing an effector cell surface phenotype in the lungs of mice chronically infected with Mycobacterium tuberculosis
-
Junqueira-Kipnis A.P., Turner J., Gonzalez-Juarrero M., Turner O.C., and Orme I.M. Stable T-cell population expressing an effector cell surface phenotype in the lungs of mice chronically infected with Mycobacterium tuberculosis. Infect Immun 72 (2004) 570-575
-
(2004)
Infect Immun
, vol.72
, pp. 570-575
-
-
Junqueira-Kipnis, A.P.1
Turner, J.2
Gonzalez-Juarrero, M.3
Turner, O.C.4
Orme, I.M.5
-
93
-
-
0036604427
-
Multiple mechanisms compensate to enhance tumor-protective CD8(+) T cell response in the long-term despite poor CD8(+) T cell priming initially: comparison between an acute versus a chronic intracellular bacterium expressing a model antigen
-
Dudani R., Chapdelaine Y., Faassen H.H., Smith D.K., Shen H., Krishnan L., and Sad S. Multiple mechanisms compensate to enhance tumor-protective CD8(+) T cell response in the long-term despite poor CD8(+) T cell priming initially: comparison between an acute versus a chronic intracellular bacterium expressing a model antigen. J Immunol 168 (2002) 5737-5745
-
(2002)
J Immunol
, vol.168
, pp. 5737-5745
-
-
Dudani, R.1
Chapdelaine, Y.2
Faassen, H.H.3
Smith, D.K.4
Shen, H.5
Krishnan, L.6
Sad, S.7
-
94
-
-
22344448429
-
Properties and protective value of the secondary versus primary T helper type 1 response to airborne Mycobacterium tuberculosis infection in mice
-
Jung Y.J., Ryan L., LaCourse R., and North R.J. Properties and protective value of the secondary versus primary T helper type 1 response to airborne Mycobacterium tuberculosis infection in mice. J Exp Med 201 (2005) 1915-1924
-
(2005)
J Exp Med
, vol.201
, pp. 1915-1924
-
-
Jung, Y.J.1
Ryan, L.2
LaCourse, R.3
North, R.J.4
-
95
-
-
27944445029
-
Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung
-
de Bree G.J., van Leeuwen E.M., Out T.A., Jansen H.M., Jonkers R.E., and van Lier R.A. Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung. J Exp Med 202 (2005) 1433-1442
-
(2005)
J Exp Med
, vol.202
, pp. 1433-1442
-
-
de Bree, G.J.1
van Leeuwen, E.M.2
Out, T.A.3
Jansen, H.M.4
Jonkers, R.E.5
van Lier, R.A.6
-
96
-
-
17844395487
-
Reducing the stimulation of CD8+ T cells during infection with intracellular bacteria promotes differentiation primarily into a central (CD62LhighCD44high) subset
-
van Faassen H., Saldanha M., Gilbertson D., Dudani R., Krishnan L., and Sad S. Reducing the stimulation of CD8+ T cells during infection with intracellular bacteria promotes differentiation primarily into a central (CD62LhighCD44high) subset. J Immunol 174 (2005) 5341-5350
-
(2005)
J Immunol
, vol.174
, pp. 5341-5350
-
-
van Faassen, H.1
Saldanha, M.2
Gilbertson, D.3
Dudani, R.4
Krishnan, L.5
Sad, S.6
-
97
-
-
0042834294
-
Reactivation of latent tuberculosis infection in TNF-deficient mice
-
Botha T., and Ryffel B. Reactivation of latent tuberculosis infection in TNF-deficient mice. J Immunol 171 (2003) 3110-3118
-
(2003)
J Immunol
, vol.171
, pp. 3110-3118
-
-
Botha, T.1
Ryffel, B.2
-
98
-
-
0033972620
-
CD4(+) T-cell subsets that mediate immunological memory to Mycobacterium tuberculosis infection in mice
-
Andersen P., and Smedegaard B. CD4(+) T-cell subsets that mediate immunological memory to Mycobacterium tuberculosis infection in mice. Infect Immun 68 (2000) 621-629
-
(2000)
Infect Immun
, vol.68
, pp. 621-629
-
-
Andersen, P.1
Smedegaard, B.2
-
99
-
-
0037180806
-
Immunology: remembrance of things past
-
Bevan M.J. Immunology: remembrance of things past. Nature 420 (2002) 748-749
-
(2002)
Nature
, vol.420
, pp. 748-749
-
-
Bevan, M.J.1
-
100
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
+ T cells and T-cell exhaustion in mice chronically infected with lymphocytic choriomeningitis virus (LCMV). The identification of a specific mechanism of T-cell exhaustion defines a potentially effective immunological strategy for the treatment of chronic infections including tuberculosis.
-
+ T cells and T-cell exhaustion in mice chronically infected with lymphocytic choriomeningitis virus (LCMV). The identification of a specific mechanism of T-cell exhaustion defines a potentially effective immunological strategy for the treatment of chronic infections including tuberculosis.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
101
-
-
20244374636
-
Intracellular expression of interleukin-4 and interferon-gamma by a Mycobacterium tuberculosis antigen-stimulated CD4+ CD57+ T-cell subpopulation with memory phenotype in tuberculosis patients
-
Jimenez-Martinez M.C., Linares M., Baez R., Montano L.F., Martinez-Cairo S., Gorocica P., Chavez R., Zenteno E., and Lascurain R. Intracellular expression of interleukin-4 and interferon-gamma by a Mycobacterium tuberculosis antigen-stimulated CD4+ CD57+ T-cell subpopulation with memory phenotype in tuberculosis patients. Immunology 111 (2004) 100-106
-
(2004)
Immunology
, vol.111
, pp. 100-106
-
-
Jimenez-Martinez, M.C.1
Linares, M.2
Baez, R.3
Montano, L.F.4
Martinez-Cairo, S.5
Gorocica, P.6
Chavez, R.7
Zenteno, E.8
Lascurain, R.9
-
102
-
-
16844386089
-
Regulation of mature T cell homeostasis
-
Surh C.D., and Sprent J. Regulation of mature T cell homeostasis. Semin Immunol 17 (2005) 183-191
-
(2005)
Semin Immunol
, vol.17
, pp. 183-191
-
-
Surh, C.D.1
Sprent, J.2
-
103
-
-
0037124329
-
Multiple choices: regulation of memory CD8 T cell generation and homeostasis by interleukin (IL)-7 and IL-15
-
Prlic M., Lefrancois L., and Jameson S.C. Multiple choices: regulation of memory CD8 T cell generation and homeostasis by interleukin (IL)-7 and IL-15. J Exp Med 195 (2002) F49-F52
-
(2002)
J Exp Med
, vol.195
-
-
Prlic, M.1
Lefrancois, L.2
Jameson, S.C.3
-
104
-
-
17644378106
-
Induction of Mycobacterium tuberculosis-specific primary and secondary T-cell responses in interleukin-15-deficient mice
-
Lazarevic V., Yankura D.J., DiVito S.J., and Flynn J.L. Induction of Mycobacterium tuberculosis-specific primary and secondary T-cell responses in interleukin-15-deficient mice. Infect Immun 73 (2005) 2910-2922
-
(2005)
Infect Immun
, vol.73
, pp. 2910-2922
-
-
Lazarevic, V.1
Yankura, D.J.2
DiVito, S.J.3
Flynn, J.L.4
-
105
-
-
18244371047
-
Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool
-
+ T cell effector activities. These results show adjuvant activity of IL-15 and demonstrate that IL-7 also serves as potent vaccine adjuvant.
-
+ T cell effector activities. These results show adjuvant activity of IL-15 and demonstrate that IL-7 also serves as potent vaccine adjuvant.
-
(2005)
J Clin Invest
, vol.115
, pp. 1177-1187
-
-
Melchionda, F.1
Fry, T.J.2
Milliron, M.J.3
McKirdy, M.A.4
Tagaya, Y.5
Mackall, C.L.6
-
106
-
-
0141446040
-
Interleukin-15 as an immune adjuvant to increase the efficacy of Mycobacterium bovis bacillus calmette-guerin vaccination
-
Umemura M., Nishimura H., Saito K., Yajima T., Matsuzaki G., Mizuno S., Sugawara I., and Yoshikai Y. Interleukin-15 as an immune adjuvant to increase the efficacy of Mycobacterium bovis bacillus calmette-guerin vaccination. Infect Immun 71 (2003) 6045-6048
-
(2003)
Infect Immun
, vol.71
, pp. 6045-6048
-
-
Umemura, M.1
Nishimura, H.2
Saito, K.3
Yajima, T.4
Matsuzaki, G.5
Mizuno, S.6
Sugawara, I.7
Yoshikai, Y.8
-
107
-
-
0242410927
-
Increased CD8+ T cell memory to concurrent infection at the expense of increased erosion of pre-existing memory: the paradoxical role of IL-15
-
Chapdelaine Y., Smith D.K., Pedras-Vasconcelos J.A., Krishnan L., and Sad S. Increased CD8+ T cell memory to concurrent infection at the expense of increased erosion of pre-existing memory: the paradoxical role of IL-15. J Immunol 171 (2003) 5454-5460
-
(2003)
J Immunol
, vol.171
, pp. 5454-5460
-
-
Chapdelaine, Y.1
Smith, D.K.2
Pedras-Vasconcelos, J.A.3
Krishnan, L.4
Sad, S.5
-
108
-
-
0041381363
-
+ effector and memory T cell generation
-
+ effector and memory T cell generation. Nat Immunol 4 (2003) 835-842
-
(2003)
Nat Immunol
, vol.4
, pp. 835-842
-
-
Seder, R.A.1
Ahmed, R.2
-
110
-
-
23944464994
-
Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein
-
Irwin S.M., Izzo A.A., Dow S.W., Skeiky Y.A., Reed S.G., Alderson M.R., and Orme I.M. Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein. Infect Immun 73 (2005) 5809-5816
-
(2005)
Infect Immun
, vol.73
, pp. 5809-5816
-
-
Irwin, S.M.1
Izzo, A.A.2
Dow, S.W.3
Skeiky, Y.A.4
Reed, S.G.5
Alderson, M.R.6
Orme, I.M.7
|