CD4+CD25+ cell depletion from the normal CD4 + T cell pool prevents tolerance toward the intestinal flora and leads to chronic colitis in immunodeficient mice

Inflammatory Bowel Diseases

Volumn 12, Issue 6, 2006, Pages 437-446

  Veltkamp, Claudia ^a   Ruhwald, Rebecca ^a   Giesem, Thomas ^a   Autschbach, Frank ^a   Kaden, Ines ^a   Veltkamp, Roland ^a   Sartor, R Balfour ^b   Stremmel, Wolfgang ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Colitogenic T cells; Cytokines; Inflammatory bowel disease; Regulatory CD4 +CD25+ cells; Tg 26 mice

Indexed keywords

BACTERIAL ANTIGEN; CYTOKINE; GAMMA INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CELL TRANSFER; CELLULAR IMMUNITY; CHRONIC DISEASE; COLITIS; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE SEVERITY; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; IMMUNOPATHOGENESIS; IMMUNOREACTIVITY; INTESTINE FLORA; KNOCKOUT MOUSE; LYMPHOCYTE FUNCTION; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TH1 CELL;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; COLITIS; DISEASE MODELS, ANIMAL; IMMUNE TOLERANCE; IMMUNOCOMPROMISED HOST; INTESTINES; LYMPH NODES; LYMPHOCYTE DEPLETION; MESENTERY; MICE; RECEPTORS, INTERLEUKIN-2; SPLEEN; T-LYMPHOCYTE SUBSETS;

EID: 33745255734     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/00054725-200606000-00002     Document Type: Article

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